Development Level

Tbio 180 | 11,178
Tchem 50 | 1,885
Tclin 36 | 612
Tdark 8 | 6,569

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 16 | 979
preweaning lethality, incomple... 11 | 499
abnormal behavior 5 | 298
decreased bone mineral content 5 | 151
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
abnormal gait 4 | 69
decreased circulating LDL chol... 4 | 38
decreased circulating glucose ... 4 | 126
decreased fasted circulating g... 4 | 65
decreased grip strength 4 | 116
decreased lean body mass 4 | 135
hyperactivity 4 | 148
hypoactivity 4 | 132
increased total body fat amoun... 4 | 134
decreased circulating alkaline... 3 | 46
decreased circulating aspartat... 3 | 34
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
embryonic lethality prior to t... 3 | 278
improved glucose tolerance 3 | 79
increased circulating sodium l... 3 | 71
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
tremors 3 | 39
abnormal craniofacial morpholo... 2 | 33
abnormal cranium morphology 2 | 36
abnormal digit morphology 2 | 10
abnormal facial morphology 2 | 17
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
convulsive seizures 2 | 13
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating serum al... 2 | 82
decreased lactate dehydrogenas... 2 | 16
decreased leukocyte cell numbe... 2 | 73
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
edema 2 | 59
embryonic lethality prior to o... 2 | 239
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased circulating LDL chol... 2 | 13
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
limb grasping 2 | 41
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal lung morphology 1 | 26
abnormal snout morphology 1 | 23
abnormal spine curvature 1 | 9
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased neutrophil cell numb... 1 | 42
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
hemorrhage 1 | 23
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
premature death 1 | 5
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

Carcinoma 165 | 11,192
psoriasis 120 | 6,514
Cancer 119 | 2,388
ovarian cancer 105 | 8,297
glioblastoma 104 | 5,635
ependymoma 97 | 4,559
osteosarcoma 95 | 7,766
lung cancer 92 | 4,607
Schizophrenia 88 | 1,136
diabetes mellitus 88 | 1,683
atypical teratoid / rhabdoid tumor 86 | 4,971
medulloblastoma, large-cell 80 | 6,086
Breast cancer 73 | 3,469
Astrocytoma, Pilocytic 72 | 3,006
oligodendroglioma 72 | 2,768
Obesity 71 | 655
adult high grade glioma 69 | 3,701
group 3 medulloblastoma 67 | 4,002
Alzheimer's disease 64 | 640
intraductal papillary-mucinous adenoma (IPMA) 64 | 2,872
Hypertension 63 | 372
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,204
Depressive disorder 62 | 401
malignant mesothelioma 61 | 3,135
Autosomal recessive predisposition 60 | 1,407
Cerebrovascular disease 60 | 223
astrocytic glioma 59 | 2,530
lung carcinoma 59 | 2,755
intraductal papillary-mucinous carcinoma (IPMC) 58 | 2,902
invasive ductal carcinoma 57 | 2,867
Bipolar Disorder 55 | 646
primitive neuroectodermal tumor 55 | 2,957
Neuropathy 54 | 254
Epilepsy 53 | 775
Heart disease 53 | 288
Kidney cancer 53 | 2,548
Mental Depression 50 | 325
lung adenocarcinoma 49 | 2,627
pancreatic cancer 48 | 2,322
Kidney disease 47 | 411
Toxic encephalopathy 47 | 139
pituitary cancer 47 | 1,915
Parkinson's disease 46 | 378
Myopathy 45 | 185
colon cancer 45 | 1,428
non-small cell lung cancer 45 | 2,799
ulcerative colitis 45 | 1,765
Seizures 44 | 584
interstitial cystitis 42 | 2,237
ductal carcinoma in situ 41 | 1,686
subependymal giant cell astrocytoma 41 | 2,230
breast carcinoma 39 | 1,589
Major Depressive Disorder 38 | 293
cystic fibrosis 38 | 1,629
Alcoholic Intoxication, Chronic 37 | 283
Atherosclerosis 37 | 276
Neurodegenerative disease 36 | 402
Brain disease 34 | 95
Hyperglycemia 33 | 134
Pick disease 33 | 1,856
Coronary artery disease 32 | 253
Mood Disorders 32 | 181
Unipolar Depression 32 | 244
Dementia 31 | 172
Liver disease 31 | 227
Asthma 30 | 370
Diarrhea 30 | 245
Hypertensive disease 30 | 278
Pain agnosia 30 | 99
adrenocortical carcinoma 30 | 1,385
Melanoma 29 | 689
Osteoporosis 29 | 348
acute quadriplegic myopathy 29 | 1,133
Down syndrome 28 | 480
Intellectual disability 28 | 998
tuberculosis 28 | 1,963
Autistic Disorder 27 | 358
Liver Cirrhosis, Experimental 27 | 733
Constipation 26 | 174
Duchenne muscular dystrophy 26 | 587
group 4 medulloblastoma 26 | 1,806
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,911
Adenoma 24 | 159
Arthritis 24 | 276
Cataract 24 | 290
Endometriosis 24 | 521
Hyperalgesia 24 | 80
Lung disease 24 | 135
Multiple Sclerosis 24 | 527
primary pancreatic ductal adenocarcinoma 24 | 1,071
Anemia 23 | 353
Heart failure 23 | 157
Hypothyroidism 23 | 115
Liver cancer 23 | 589
Nerve Degeneration 23 | 118
Pancreatitis 23 | 118
Amyotrophic lateral sclerosis 22 | 437
Infantile onset 22 | 236
Skin cancer 22 | 451
astrocytoma 22 | 1,113

Tissue

Endocrine System 261 | 18,159
Digestive Tract 256 | 17,369
Skin and soft tissues 255 | 17,230
Female tissues 248 | 17,400
Nervous System 246 | 16,725
Male tissues 245 | 17,142
Liver and Pancreas 241 | 16,750
Blood and immune system 239 | 16,909
Urinary Tract 238 | 16,678
Respiratory system 224 | 16,393
Cardiovascular System 206 | 15,192

Target Family

Non-IDG 177 | 12,091
Enzyme 49 | 4,145
Ion Channel 11 | 344
Transcription Factor 11 | 1,400
Transporter 10 | 473
Kinase 9 | 634
GPCR 6 | 408
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Fiber 274 | 274
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Appetite-regulating hormone GHRL Tchem Non-IDG -3.63688 5052.5 631
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Ryanodine receptor 1 RYR1 Tclin Ion Channel -3.00978 1018.9 103
Bone sialoprotein 2 IBSP Tbio Non-IDG -2.95483 756.8 261
Vinculin VCL Tbio Non-IDG -3.34872 2107.1 637
Plasminogen-like protein A PLGLA Tdark Non-IDG -3.96245 15129.1 0
BDNF/NT-3 growth factors receptor NTRK2 Tchem Kinase -3.14477 1170.3 947
2,4-dienoyl-CoA reductase, mitochondrial DECR1 Tbio Enzyme -4.22091 15887.9 151