Development Level

Tbio 192 | 11,651
Tchem 38 | 1,388
Tclin 36 | 612
Tdark 8 | 6,593

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 16 | 979
preweaning lethality, incomple... 11 | 499
abnormal behavior 5 | 298
decreased bone mineral content 5 | 151
abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
abnormal gait 4 | 69
decreased circulating LDL chol... 4 | 38
decreased circulating glucose ... 4 | 126
decreased fasted circulating g... 4 | 65
decreased grip strength 4 | 116
decreased lean body mass 4 | 135
hyperactivity 4 | 148
hypoactivity 4 | 132
increased total body fat amoun... 4 | 134
decreased circulating alkaline... 3 | 46
decreased circulating aspartat... 3 | 34
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
embryonic lethality prior to t... 3 | 278
improved glucose tolerance 3 | 79
increased circulating sodium l... 3 | 71
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
tremors 3 | 39
abnormal craniofacial morpholo... 2 | 33
abnormal cranium morphology 2 | 36
abnormal digit morphology 2 | 10
abnormal facial morphology 2 | 17
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
cardiovascular system phenotyp... 2 | 36
convulsive seizures 2 | 13
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating serum al... 2 | 82
decreased lactate dehydrogenas... 2 | 16
decreased leukocyte cell numbe... 2 | 73
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
edema 2 | 59
embryonic lethality prior to o... 2 | 239
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased body length 2 | 32
increased circulating LDL chol... 2 | 13
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
limb grasping 2 | 41
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal lung morphology 1 | 26
abnormal snout morphology 1 | 23
abnormal spine curvature 1 | 9
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased neutrophil cell numb... 1 | 42
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
hemorrhage 1 | 23
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
premature death 1 | 5
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

Carcinoma 170 | 11,493
Cancer 126 | 2,499
psoriasis 126 | 6,694
ovarian cancer 110 | 8,520
glioblastoma 108 | 5,792
ependymoma 100 | 4,679
osteosarcoma 98 | 7,950
lung cancer 97 | 4,740
diabetes mellitus 93 | 1,728
Schizophrenia 91 | 1,160
atypical teratoid / rhabdoid tumor 89 | 5,112
medulloblastoma, large-cell 81 | 6,241
Breast cancer 77 | 3,578
Astrocytoma, Pilocytic 74 | 3,081
Obesity 74 | 678
oligodendroglioma 74 | 2,850
adult high grade glioma 71 | 3,801
Hypertension 69 | 396
group 3 medulloblastoma 68 | 4,104
Alzheimer's disease 67 | 658
malignant mesothelioma 66 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 65 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 65 | 3,291
Cerebrovascular disease 64 | 238
Depressive disorder 64 | 409
Autosomal recessive predisposition 62 | 1,442
lung carcinoma 62 | 2,843
astrocytic glioma 61 | 2,597
invasive ductal carcinoma 60 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 59 | 2,989
Heart disease 58 | 306
Bipolar Disorder 57 | 666
primitive neuroectodermal tumor 56 | 3,035
Epilepsy 55 | 792
Kidney cancer 55 | 2,613
Neuropathy 55 | 261
lung adenocarcinoma 53 | 2,716
Kidney disease 52 | 430
Mental Depression 52 | 333
pancreatic cancer 52 | 2,398
Toxic encephalopathy 49 | 141
ulcerative colitis 49 | 1,819
Parkinson's disease 48 | 392
colon cancer 48 | 1,478
non-small cell lung cancer 48 | 2,890
pituitary cancer 48 | 1,972
Seizures 46 | 596
Myopathy 45 | 185
interstitial cystitis 45 | 2,312
ductal carcinoma in situ 44 | 1,745
subependymal giant cell astrocytoma 43 | 2,287
breast carcinoma 42 | 1,638
Atherosclerosis 41 | 291
cystic fibrosis 41 | 1,696
Alcoholic Intoxication, Chronic 39 | 289
Major Depressive Disorder 39 | 301
Neurodegenerative disease 37 | 414
Brain disease 35 | 96
Coronary artery disease 35 | 268
Hypertensive disease 35 | 292
Liver Cirrhosis, Experimental 34 | 769
Liver disease 34 | 237
Pick disease 34 | 1,894
Asthma 33 | 385
Hyperglycemia 33 | 137
Osteoporosis 33 | 363
Unipolar Depression 33 | 250
Dementia 32 | 175
Mood Disorders 32 | 184
Pain agnosia 32 | 104
adrenocortical carcinoma 32 | 1,428
tuberculosis 31 | 2,010
Arthritis 30 | 290
Diarrhea 30 | 253
Down syndrome 30 | 499
Intellectual disability 30 | 1,016
acute quadriplegic myopathy 30 | 1,158
Melanoma 29 | 711
Duchenne muscular dystrophy 28 | 601
Endometriosis 28 | 540
Autistic Disorder 27 | 364
Constipation 27 | 181
Lung disease 27 | 142
Multiple Sclerosis 27 | 540
group 4 medulloblastoma 27 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,962
primary pancreatic ductal adenocarcinoma 27 | 1,109
Hyperalgesia 26 | 83
Adenoma 24 | 167
Cataract 24 | 297
Inflammation 24 | 120
Nerve Degeneration 24 | 121
Pancreatitis 24 | 123
Rheumatoid arthritis 24 | 1,191
astrocytoma 24 | 1,146
Amyotrophic lateral sclerosis 23 | 451
Anemia 23 | 365
Hypothyroidism 23 | 122
Infantile onset 23 | 238
Liver cancer 23 | 604

Tissue

Endocrine System 261 | 18,159
Digestive Tract 256 | 17,369
Skin and soft tissues 255 | 17,230
Female tissues 248 | 17,400
Nervous System 246 | 16,725
Male tissues 245 | 17,142
Liver and Pancreas 241 | 16,750
Blood and immune system 239 | 16,909
Urinary Tract 238 | 16,678
Respiratory system 224 | 16,393
Cardiovascular System 206 | 15,192

Target Family

Non-IDG 177 | 12,091
Enzyme 49 | 4,145
Ion Channel 11 | 344
Transcription Factor 11 | 1,400
Transporter 10 | 473
Kinase 9 | 634
GPCR 6 | 408
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Fiber 274 | 274
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Suppressor of SWI4 1 homolog PPAN-P2RY11 Tbio Non-IDG -2.66392 881.0 97
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
Nucleolysin TIA-1 isoform p40 TIA1 Tbio Non-IDG -2.86461 714.2 314
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075