Development Level

Tbio 172 | 10,625
Tchem 50 | 1,890
Tclin 31 | 602
Tdark 10 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 13 | 633
abnormal behavior 7 | 226
decreased lean body mass 6 | 195
decreased grip strength 5 | 123
decreased total body fat amoun... 5 | 186
embryonic lethality prior to t... 5 | 187
preweaning lethality, incomple... 5 | 260
decreased bone mineral content 4 | 157
increased circulating alkaline... 4 | 119
increased or absent threshold ... 4 | 128
short tibia 4 | 82
tremors 4 | 34
abnormal bone structure 3 | 131
abnormal embryo size 3 | 112
abnormal gait 3 | 51
abnormal retina morphology 3 | 100
abnormal sleep behavior 3 | 63
decreased circulating alkaline... 3 | 41
decreased circulating glucose ... 3 | 121
decreased mean corpuscular vol... 3 | 50
improved glucose tolerance 3 | 56
increased hemoglobin content 3 | 45
increased lean body mass 3 | 107
abnormal craniofacial morpholo... 2 | 12
abnormal cranium morphology 2 | 32
abnormal facial morphology 2 | 9
abnormal skin morphology 2 | 23
abnormal tooth morphology 2 | 24
convulsive seizures 2 | 11
decreased body length 2 | 108
decreased body weight 2 | 174
decreased circulating LDL chol... 2 | 37
decreased circulating insulin ... 2 | 75
decreased fasted circulating g... 2 | 49
decreased heart weight 2 | 44
decreased vertical activity 2 | 22
embryonic lethality prior to o... 2 | 148
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased circulating LDL chol... 2 | 15
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 24
increased exploration in new e... 2 | 56
increased gamma-delta T cell n... 2 | 16
increased hematocrit 2 | 36
increased mean corpuscular hem... 2 | 93
increased startle reflex 2 | 38
limb grasping 2 | 35
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal eyelid morphology 1 | 6
abnormal head shape 1 | 4
abnormal head size 1 | 1
abnormal kidney morphology 1 | 30
abnormal lung morphology 1 | 15
abnormal neural tube closure 1 | 37
abnormal retinal blood vessel ... 1 | 18
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal thoracic vertebrae mo... 1 | 16
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
absent teeth 1 | 4
cleft palate 1 | 6
craniofacial phenotype 1 | 9
decreased alpha-beta T cell nu... 1 | 12
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 31
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased exploration in new e... 1 | 9
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased pulmonary respirator... 1 | 4
decreased threshold for audito... 1 | 32
decreased total retina thickne... 1 | 20
enlarged lymph nodes 1 | 27
facial cleft 1 | 3
hemorrhage 1 | 12
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating serum al... 1 | 25
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 25
increased rib number 1 | 41
mydriasis 1 | 9
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
small adrenal glands 1 | 15
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

Cancer 119 | 2,346
psoriasis 118 | 6,685
ovarian cancer 105 | 8,484
glioblastoma 97 | 5,572
osteosarcoma 95 | 7,933
lung cancer 93 | 4,466
diabetes mellitus 84 | 1,663
medulloblastoma, large-cell 77 | 6,234
pilocytic astrocytoma 71 | 3,086
oligodendroglioma 70 | 2,849
Obesity 66 | 616
atypical teratoid / rhabdoid tumor 64 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 64 | 2,956
malignant mesothelioma 64 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,289
lung carcinoma 60 | 2,844
Alzheimer's disease 59 | 644
invasive ductal carcinoma 58 | 2,950
Breast cancer 57 | 3,094
Cerebrovascular disease 57 | 231
intraductal papillary-mucinous carcinoma (IPMC) 57 | 2,988
pediatric high grade glioma 55 | 2,712
primitive neuroectodermal tumor 53 | 3,031
Hypertension 52 | 287
lung adenocarcinoma 52 | 2,713
Heart disease 51 | 279
Schizophrenia 51 | 501
Neuropathy 50 | 210
ulcerative colitis 50 | 2,087
pancreatic cancer 49 | 2,300
Carcinoma 47 | 2,147
Kidney disease 47 | 396
colon cancer 47 | 1,475
ependymoma 45 | 2,514
pituitary cancer 45 | 1,972
astrocytic glioma 44 | 2,241
ductal carcinoma in situ 44 | 1,745
Epilepsy 43 | 346
Myopathy 43 | 128
non-small cell lung cancer 43 | 2,798
cystic fibrosis 42 | 1,665
interstitial cystitis 42 | 2,299
subependymal giant cell astrocytoma 42 | 2,287
Toxic encephalopathy 41 | 131
Parkinson's disease 40 | 364
breast carcinoma 39 | 1,614
posterior fossa group A ependymoma 39 | 1,511
Neurodegenerative disease 37 | 383
Atherosclerosis 36 | 275
astrocytoma 36 | 1,493
sonic hedgehog group medulloblastoma 35 | 1,482
Asthma 32 | 349
Liver disease 32 | 219
acute quadriplegic myopathy 32 | 1,157
adrenocortical carcinoma 31 | 1,427
adult high grade glioma 31 | 2,148
group 3 medulloblastoma 31 | 2,254
Brain disease 30 | 83
Duchenne muscular dystrophy 30 | 602
Pain agnosia 30 | 99
Pick disease 30 | 1,893
group 4 medulloblastoma 30 | 1,875
primary pancreatic ductal adenocarcinoma 30 | 1,271
Dementia 29 | 129
Endometriosis 29 | 535
Hyperglycemia 29 | 120
Arthritis 28 | 248
Coronary artery disease 28 | 240
Diarrhea 28 | 155
Down syndrome 28 | 548
atypical teratoid/rhabdoid tumor 28 | 1,095
Osteoporosis 26 | 257
Seizures 26 | 95
posterior fossa group B ependymoma 26 | 1,530
tuberculosis 26 | 1,557
Lung disease 25 | 132
Multiple Sclerosis 25 | 498
Adenoma 24 | 165
Autistic Disorder 24 | 320
Hyperalgesia 24 | 71
Hypertensive disease 24 | 193
Metabolic syndrome X 24 | 155
Atopic dermatitis 23 | 944
Inflammation 23 | 109
Migraine 23 | 79
Pancreatitis 23 | 97
Bipolar Disorder 22 | 266
Rheumatoid Arthritis 22 | 1,160
nasopharyngeal carcinoma 22 | 1,056
Amyotrophic Lateral Sclerosis 21 | 431
Anemia 21 | 252
Hypothyroidism 21 | 89
Inflammatory bowel disease 21 | 142
Prostatic Neoplasms 21 | 471
gastric carcinoma 21 | 832
Hypoglycemia 20 | 81
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 499
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
Vascular disease 19 | 281
juvenile dermatomyositis 19 | 1,189

Tissue

Endocrine System 257 | 18,512
Nervous System 257 | 18,561
Female tissues 256 | 18,647
Digestive Tract 254 | 18,473
Skin and soft tissues 253 | 18,115
Liver and Pancreas 252 | 18,136
Urinary Tract 252 | 18,444
Cardiovascular System 250 | 17,958
Blood and immune system 247 | 17,995
Male tissues 245 | 17,969
Respiratory system 237 | 17,484

Target Family

Non-IDG 171 | 11,971
Enzyme 44 | 4,146
Ion Channel 11 | 341
Transcription Factor 11 | 1,400
Transporter 10 | 473
Kinase 9 | 634
GPCR 5 | 406
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Fiber 263 | 263
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474