Development Level

Tbio 154 | 10,625
Tchem 48 | 1,890
Tclin 10 | 602
Tdark 6 | 7,003

IMPC Phenotype

preweaning lethality, complete... 17 | 633
embryonic lethality prior to t... 7 | 187
decreased lean body mass 6 | 195
abnormal embryo size 4 | 112
decreased bone mineral content 4 | 157
embryonic lethality prior to o... 4 | 148
preweaning lethality, incomple... 4 | 260
abnormal retina morphology 3 | 100
decreased body weight 3 | 174
increased grip strength 3 | 83
increased total body fat amoun... 3 | 57
abnormal behavioral response t... 2 | 52
abnormal bone structure 2 | 131
abnormal hindbrain development 2 | 24
abnormal neural tube closure 2 | 37
abnormal sleep behavior 2 | 63
anophthalmia 2 | 20
decreased bone mineral density 2 | 126
decreased effector memory CD8-... 2 | 24
female infertility 2 | 34
hyperactivity 2 | 108
impaired glucose tolerance 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating alkaline... 2 | 119
increased heart rate 2 | 17
increased or absent threshold ... 2 | 128
increased respiratory quotient 2 | 12
limb grasping 2 | 35
male infertility 2 | 62
abnormal allantois morphology 1 | 3
abnormal brain morphology 1 | 6
abnormal coat- hair morphology 1 | 18
abnormal embryo development 1 | 2
abnormal embryo turning 1 | 15
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal eyelid aperture 1 | 3
abnormal facial morphology 1 | 9
abnormal forebrain development 1 | 18
abnormal head morphology 1 | 10
abnormal heart looping 1 | 2
abnormal heart morphology 1 | 51
abnormal maxilla morphology 1 | 16
abnormal midbrain development 1 | 22
abnormal neural tube morpholog... 1 | 8
abnormal ovary morphology 1 | 3
abnormal pericardium morpholog... 1 | 11
abnormal pharyngeal arch morph... 1 | 2
abnormal retinal outer nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal social-conspecific in... 1 | 3
abnormal startle reflex 1 | 14
abnormal tail bud morphology 1 | 6
abnormal tooth morphology 1 | 24
cleft palate 1 | 6
cyanosis 1 | 6
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating triglyce... 1 | 83
decreased exploration in new e... 1 | 9
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
decreased vertical activity 1 | 22
embryonic growth retardation 1 | 28
hydrops fetalis 1 | 22
hypoactivity 1 | 89
impaired righting response 1 | 19
increased B cell number 1 | 23
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating phosphat... 1 | 24
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased coping response 1 | 3
increased exploration in new e... 1 | 56
increased prepulse inhibition 1 | 21
increased sacral vertebrae num... 1 | 62
microphthalmia 1 | 15
pale yolk sac 1 | 12
persistence of hyaloid vascula... 1 | 22
short tibia 1 | 82
shortened ST segment 1 | 9
small adrenal glands 1 | 15
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small superior vagus ganglion 1 | 20
small testis 1 | 37

Disease

Cancer 135 | 2,346
psoriasis 101 | 6,685
ovarian cancer 97 | 8,491
osteosarcoma 91 | 7,933
medulloblastoma, large-cell 81 | 6,234
glioblastoma 79 | 5,572
lung cancer 78 | 4,473
malignant mesothelioma 65 | 3,163
Breast cancer 53 | 3,098
intraductal papillary-mucinous neoplasm (IPMN) 52 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 51 | 2,956
invasive ductal carcinoma 51 | 2,950
atypical teratoid / rhabdoid tumor 49 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 48 | 2,988
lung adenocarcinoma 48 | 2,714
primitive neuroectodermal tumor 46 | 3,031
diabetes mellitus 44 | 1,663
pediatric high grade glioma 42 | 2,712
pilocytic astrocytoma 42 | 3,086
ulcerative colitis 42 | 2,087
non-small cell lung cancer 41 | 2,798
pancreatic cancer 41 | 2,300
oligodendroglioma 39 | 2,849
group 4 medulloblastoma 37 | 1,875
cystic fibrosis 36 | 1,670
interstitial cystitis 36 | 2,299
ductal carcinoma in situ 34 | 1,745
pituitary cancer 34 | 1,972
Carcinoma 33 | 2,147
breast carcinoma 32 | 1,614
group 3 medulloblastoma 30 | 2,254
lung carcinoma 30 | 2,844
subependymal giant cell astrocytoma 29 | 2,287
ependymoma 28 | 2,514
astrocytoma 27 | 1,493
Mammary Neoplasms 26 | 410
astrocytic glioma 26 | 2,241
tuberculosis 26 | 1,563
Heart disease 25 | 279
posterior fossa group A ependymoma 25 | 1,511
primary pancreatic ductal adenocarcinoma 25 | 1,271
Rheumatoid Arthritis 24 | 1,170
Kidney disease 23 | 397
Prostatic Neoplasms 23 | 471
dermatomyositis 23 | 966
adrenocortical carcinoma 22 | 1,427
adult high grade glioma 22 | 2,148
atypical teratoid/rhabdoid tumor 22 | 1,095
juvenile dermatomyositis 22 | 1,189
sonic hedgehog group medulloblastoma 22 | 1,482
acute quadriplegic myopathy 20 | 1,157
colon cancer 20 | 1,475
Multiple myeloma 19 | 1,327
medulloblastoma 19 | 1,524
Adenoma 18 | 165
Down syndrome 18 | 548
Parkinson's disease 18 | 364
Waldenstrons macroglobulinemia 18 | 764
nasopharyngeal carcinoma 18 | 1,056
Osteoporosis 17 | 259
Pick disease 17 | 1,893
Stomach Neoplasms 17 | 282
Vascular disease 17 | 281
gastric carcinoma 17 | 832
Alzheimer's disease 16 | 644
Cleft palate 16 | 125
cutaneous lupus erythematosus 16 | 1,056
esophageal adenocarcinoma 16 | 737
Anemia 15 | 252
Colorectal Neoplasms 15 | 217
Liver disease 15 | 219
posterior fossa group B ependymoma 15 | 1,530
spina bifida 15 | 1,064
Arthritis 14 | 248
Hypertension 14 | 293
Intellectual disability 14 | 573
Lung Neoplasms 14 | 171
Cerebrovascular disease 13 | 231
Coronary artery disease 13 | 240
Craniofacial Abnormalities 13 | 147
Duchenne muscular dystrophy 13 | 602
Neoplasm Metastasis 13 | 138
Neoplastic Cell Transformation 13 | 81
Pancreatic Neoplasm 13 | 79
non-small cell lung carcinoma 13 | 413
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
Endometriosis 12 | 535
Liver carcinoma 12 | 217
Multiple Sclerosis 12 | 498
Obesity 12 | 616
Atherosclerosis 11 | 275
Infertility 11 | 163
Melanoma 11 | 261
Microphthalmia 11 | 79
Schizophrenia 11 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 499
chronic rhinosinusitis 11 | 512
interstitial lung disease 11 | 292
primary Sjogren syndrome 11 | 788
acute myeloid leukemia 10 | 785

Tissue

Endocrine System 215 | 18,511
Female tissues 214 | 18,646
Nervous System 214 | 18,560
Urinary Tract 213 | 18,443
Digestive Tract 212 | 18,472
Skin and soft tissues 211 | 18,114
Cardiovascular System 208 | 17,957
Liver and Pancreas 208 | 18,135
Male tissues 206 | 17,968
Blood and immune system 205 | 17,994
Respiratory system 197 | 17,483

Target Family

Non-IDG 81 | 11,969
Transcription Factor 80 | 1,400
Enzyme 24 | 4,146
Epigenetic 16 | 242
Nuclear Receptor 6 | 48
TF/Epigenetic 5 | 38
Kinase 4 | 634
GPCR 2 | 408

Jensen-TM Tissue

Embryonic stem cell 218 | 218
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.73870 492.7 294
E3 ubiquitin-protein ligase RLIM RLIM Tbio Enzyme -1.57212 36.3 141
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.03044 1092.0 356
Methylcytosine dioxygenase TET3 TET3 Tbio Enzyme -1.88050 66.7 105
Prominin-1 PROM1 Tbio Non-IDG -3.27144 1922.5 226
Histone-lysine N-methyltransferase SUV39H1 SUV39H1 Tchem Epigenetic -2.21810 149.4 267
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.75815 5706.6 1539
Pro-epidermal growth factor EGF Tbio Non-IDG -3.74596 4837.7 851
Paired amphipathic helix protein Sin3a SIN3A Tbio Non-IDG -1.89468 62.9 159
POU domain, class 5, transcription factor 1 POU5F1 Tbio Transcription Factor -3.28009 1980.8 817