Development Level

Tbio 34 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased body weight 3 | 161
decreased circulating alanine ... 2 | 47
decreased circulating choleste... 2 | 93
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
abnormal coat- hair morphology 1 | 19
abnormal hair texture 1 | 4
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased food intake 1 | 13
embryonic lethality prior to o... 1 | 239
hypoactivity 1 | 132
increased CD4-positive, alpha ... 1 | 4
increased circulating bilirubi... 1 | 16
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
tremors 1 | 39

Disease

Carcinoma 27 | 11,493
osteosarcoma 24 | 7,950
ovarian cancer 22 | 8,520
medulloblastoma, large-cell 20 | 6,241
psoriasis 19 | 6,694
group 3 medulloblastoma 18 | 4,104
glioblastoma 16 | 5,792
lung cancer 16 | 4,740
Cancer 15 | 2,499
atypical teratoid / rhabdoid tumor 14 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
Breast cancer 13 | 3,578
non-small cell lung cancer 13 | 2,890
ependymoma 12 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
primitive neuroectodermal tumor 12 | 3,035
malignant mesothelioma 11 | 3,232
lung adenocarcinoma 10 | 2,716
adult high grade glioma 9 | 3,801
invasive ductal carcinoma 9 | 2,951
Intellectual disability 7 | 1,016
Kidney cancer 7 | 2,613
adrenocortical carcinoma 7 | 1,428
oligodendroglioma 7 | 2,850
Endometriosis 6 | 540
Pick disease 6 | 1,894
Short stature 6 | 531
breast carcinoma 6 | 1,638
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
Dull intelligence 5 | 645
Fanconi anemia 5 | 56
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Small head 5 | 374
Waldenstrons macroglobulinemia 5 | 765
astrocytic glioma 5 | 2,597
diabetes mellitus 5 | 1,728
nasopharyngeal carcinoma 5 | 1,058
pancreatic cancer 5 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary Sjogren syndrome 5 | 735
Astrocytoma, Pilocytic 4 | 3,081
Atopic dermatitis 4 | 952
Bloom syndrome 4 | 29
Breast Neoplasms 4 | 445
Chromosome Breakage 4 | 36
Cognitive delay 4 | 608
Decreased platelet count 4 | 111
Global developmental delay 4 | 608
Mammary Neoplasms 4 | 425
Mental and motor retardation 4 | 608
Multiple myeloma 4 | 1,332
Thrombocytopenia 4 | 197
Werner syndrome 4 | 29
Xeroderma pigmentosum 4 | 43
interstitial cystitis 4 | 2,312
lung carcinoma 4 | 2,843
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Acquired scoliosis 3 | 281
Almond-shaped eyes 3 | 23
Anemia 3 | 365
Autosomal recessive predisposition 3 | 1,442
Curvature of spine 3 | 282
Delayed bone age 3 | 136
Increased chromosomal breakage 3 | 27
Irregular hyperpigmentation 3 | 33
Leukopenia 3 | 72
Neutrophil count decreased 3 | 47
Nijmegen breakage syndrome 3 | 24
Pyridoxine-responsive sideroblastic anemia 3 | 17
Radial aplasia/hypoplasia 3 | 29
Short palpebral fissure 3 | 38
Xeroderma pigmentosum group F 3 | 22
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
group 4 medulloblastoma 3 | 1,855
hypopigmented skin patch 3 | 59
subependymal giant cell astrocytoma 3 | 2,287
Blepharoptosis 2 | 231
Congenital clubfoot 2 | 109
Epilepsy 2 | 792
Glaucoma 2 | 239
Hemoglobin low 2 | 124
Liver cancer 2 | 604
Low Birth Weights 2 | 69
Narrow forehead 2 | 34
Pancytopenia 2 | 45
Small for gestational age (disorder) 2 | 69
Strabismus 2 | 270
acute quadriplegic myopathy 2 | 1,158
cutaneous lupus erythematosus 2 | 1,057
medulloblastoma 2 | 720
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 38 | 16,909
Cardiovascular System 38 | 15,192
Digestive Tract 38 | 17,369
Endocrine System 38 | 18,159
Female tissues 38 | 17,400
Liver and Pancreas 38 | 16,750
Male tissues 38 | 17,142
Nervous System 38 | 16,725
Respiratory system 38 | 16,393
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678

Target Family

Non-IDG 24 | 12,091
Enzyme 11 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634
Transporter 1 | 473

Jensen-TM Tissue

DT-40 cell 38 | 38
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
N-acetyltransferase ESCO1 ESCO1 Tbio Enzyme -1.65145 44.6 49
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.17933 148.4 308
Exosome complex exonuclease RRP44 DIS3 Tbio Enzyme -1.80730 64.2 141
DNA repair protein XRCC3 XRCC3 Tbio Non-IDG -2.50791 314.0 414
Structural maintenance of chromosomes protein 6 SMC6 Tbio Non-IDG -1.42371 20.0 115
Fanconi anemia group D2 protein FANCD2 Tbio Non-IDG -2.59123 391.6 404
DNA repair protein REV1 REV1 Tbio Non-IDG -2.43956 286.1 101
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 SSU72 Tbio Enzyme -1.45153 34.4 60
Single-stranded DNA cytosine deaminase AICDA Tbio Enzyme -2.85153 635.3 302
DIS3-like exonuclease 1 DIS3L Tdark Enzyme -0.68418 3.89 94