Development Level

Tbio 131 | 10,625
Tchem 42 | 1,890
Tclin 11 | 602
Tdark 2 | 7,003

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

abnormal behavior 4 | 226
preweaning lethality, complete... 4 | 633
decreased bone mineral content 3 | 157
decreased circulating insulin ... 3 | 75
increased grip strength 3 | 83
abnormal bone structure 2 | 131
abnormal femur morphology 2 | 14
abnormal lens morphology 2 | 73
abnormal tail morphology 2 | 17
cataract 2 | 26
decreased NK T cell number 2 | 28
decreased blood urea nitrogen ... 2 | 31
decreased body length 2 | 108
decreased heart weight 2 | 44
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
decreased mature B cell number 2 | 25
enlarged heart 2 | 111
increased NK cell number 2 | 19
increased circulating alkaline... 2 | 119
increased effector memory CD4-... 2 | 15
increased effector memory CD8-... 2 | 14
increased red blood cell distr... 2 | 21
male infertility 2 | 62
short tibia 2 | 82
abnormal body size 1 | 1
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 14
abnormal lip morphology 1 | 2
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal optic disc morphology 1 | 10
abnormal radius morphology 1 | 8
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
abnormal spleen morphology 1 | 36
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 14
abnormal vertebral arch morpho... 1 | 9
absent startle reflex 1 | 15
corneal opacity 1 | 25
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating iron lev... 1 | 25
decreased circulating phosphat... 1 | 15
decreased circulating potassiu... 1 | 17
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased kidney weight 1 | 7
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
herniated abdominal wall 1 | 4
hydrops fetalis 1 | 22
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
increased CD4-positive, alpha ... 1 | 15
increased Ly6C high monocyte n... 1 | 12
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating potassiu... 1 | 31
increased circulating total pr... 1 | 20
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased heart rate 1 | 17
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
irregularly shaped pupil 1 | 7
limb grasping 1 | 35
mydriasis 1 | 9
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
short tail 1 | 4
small testis 1 | 37
thick tail 1 | 1
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

Cancer 117 | 2,346
psoriasis 99 | 6,685
ovarian cancer 88 | 8,491
lung cancer 77 | 4,473
diabetes mellitus 74 | 1,663
osteosarcoma 73 | 7,933
glioblastoma 68 | 5,572
Kidney disease 66 | 397
malignant mesothelioma 62 | 3,163
invasive ductal carcinoma 59 | 2,950
pancreatic cancer 58 | 2,300
cystic fibrosis 57 | 1,670
interstitial cystitis 57 | 2,299
ulcerative colitis 57 | 2,087
pilocytic astrocytoma 56 | 3,086
Arthritis 55 | 248
intraductal papillary-mucinous neoplasm (IPMN) 55 | 3,289
lung carcinoma 54 | 2,844
Breast cancer 53 | 3,098
non-small cell lung cancer 52 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 51 | 2,956
lung adenocarcinoma 50 | 2,714
Liver disease 47 | 219
intraductal papillary-mucinous carcinoma (IPMC) 47 | 2,988
medulloblastoma, large-cell 47 | 6,234
Hypersensitivity reaction type II disease 46 | 235
Multiple Sclerosis 46 | 498
atypical teratoid / rhabdoid tumor 45 | 4,369
Carcinoma 42 | 2,147
ductal carcinoma in situ 42 | 1,745
tuberculosis 42 | 1,563
pituitary cancer 39 | 1,972
posterior fossa group A ependymoma 37 | 1,511
Anemia 35 | 252
Heart disease 35 | 279
breast carcinoma 35 | 1,614
primary pancreatic ductal adenocarcinoma 35 | 1,271
Uveitis 33 | 103
pediatric high grade glioma 33 | 2,712
Hepatitis B 31 | 103
Inflammatory bowel disease 31 | 142
Lung disease 31 | 136
gastric carcinoma 30 | 832
nasopharyngeal carcinoma 30 | 1,056
Acquired immunodeficiency syndrome 29 | 164
Asthma 29 | 349
Leprosy 29 | 77
Vascular disease 29 | 281
primitive neuroectodermal tumor 29 | 3,031
Ankylosing spondylitis 28 | 138
Endometriosis 28 | 535
Glaucoma 28 | 135
oligodendroglioma 27 | 2,849
Hypertension 26 | 293
Primary immunodeficiency disease 26 | 52
Skin disease 26 | 65
colon cancer 26 | 1,475
subependymal giant cell astrocytoma 26 | 2,287
Atherosclerosis 25 | 275
Cerebrovascular disease 24 | 231
Dermatitis 24 | 141
Duchenne muscular dystrophy 24 | 602
Juvenile rheumatoid arthritis 24 | 105
adult high grade glioma 24 | 2,148
cutaneous lupus erythematosus 24 | 1,056
sonic hedgehog group medulloblastoma 24 | 1,482
Keratitis 23 | 42
Mammary Neoplasms 23 | 410
adrenocortical carcinoma 23 | 1,427
esophageal adenocarcinoma 23 | 737
Hemochromatosis 22 | 55
Inflammation 22 | 109
Keratoconus 22 | 49
Myopia 22 | 99
autosomal dominant Emery-Dreifuss muscular dystrophy 22 | 499
Alzheimer's disease 21 | 644
Behcet's disease 21 | 74
Birdshot chorioretinopathy 21 | 23
Neoplasm Invasiveness 21 | 127
Obesity 21 | 616
ependymoma 21 | 2,514
Coronary artery disease 20 | 240
Prostatic Neoplasms 20 | 471
Reperfusion Injury 20 | 84
astrocytoma 20 | 1,493
Allergic hypersensitivity disease 19 | 123
Atopic dermatitis 19 | 944
Neoplasm Metastasis 19 | 138
Neuropathy 19 | 210
Pulmonary Fibrosis 19 | 66
group 3 medulloblastoma 19 | 2,254
juvenile dermatomyositis 19 | 1,189
Diabetic Retinopathy 18 | 53
Eye disease 18 | 55
astrocytic glioma 18 | 2,241
group 4 medulloblastoma 18 | 1,875
periodontitis 18 | 269
posterior fossa group B ependymoma 18 | 1,530
Pneumonia 17 | 133
Rheumatoid Arthritis 17 | 1,170

Tissue

Digestive Tract 166 | 18,472
Nervous System 166 | 18,560
Urinary Tract 166 | 18,443
Endocrine System 165 | 18,511
Female tissues 165 | 18,646
Skin and soft tissues 164 | 18,114
Male tissues 163 | 17,968
Respiratory system 163 | 17,483
Cardiovascular System 162 | 17,957
Liver and Pancreas 162 | 18,135
Blood and immune system 161 | 17,994

Target Family

Non-IDG 129 | 11,969
Enzyme 32 | 4,146
Transcription Factor 10 | 1,400
Kinase 8 | 634
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 1 | 408
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Cornea 186 | 186
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interferon-induced transmembrane protein 2 IFITM2 Tbio Non-IDG -2.21851 158.1 111
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.36387 2061.0 806
Aquaporin-1 AQP1 Tbio Non-IDG -3.06090 1040.5 321
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.70375 8561.3 896
Metalloproteinase inhibitor 1 TIMP1 Tbio Enzyme -3.55219 3513.4 673
Collagen alpha-1(VIII) chain COL8A1 Tbio Non-IDG -1.25305 16.3 98
Alpha-crystallin A chain CRYAA Tbio Non-IDG -2.83468 658.4 164
Pro-epidermal growth factor EGF Tbio Non-IDG -3.74596 4837.7 851
Hepatocyte growth factor HGF Tchem Enzyme -3.29371 2317.3 573
Mucin-5AC MUC5AC Tchem Non-IDG -3.19883 932.0 284