Development Level

Tbio 27 | 11,445
Tchem 26 | 1,598
Tclin 13 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
hyperactivity 3 | 148
increased mean corpuscular hem... 3 | 96
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 36
increased startle reflex 2 | 112
male infertility 2 | 123
microphthalmia 2 | 26
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small testis 2 | 58
abnormal body wall morphology 1 | 9
abnormal bone mineralization 1 | 38
abnormal embryo development 1 | 7
abnormal epididymis morphology 1 | 42
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
absent testes 1 | 6
anophthalmia 1 | 33
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
mammalian phenotype 1 | 17
polydactyly 1 | 7
protruding tongue 1 | 3
short tibia 1 | 97
small seminal vesicle 1 | 10
small spleen 1 | 19
urinary bladder obstruction 1 | 4

Disease

Cancer 61 | 2,499
Carcinoma 53 | 11,493
ovarian cancer 51 | 8,520
glioblastoma 39 | 5,792
psoriasis 39 | 6,694
atypical teratoid / rhabdoid tumor 38 | 5,112
osteosarcoma 38 | 7,950
lung cancer 37 | 4,740
Breast cancer 32 | 3,578
Stomach Neoplasms 31 | 300
medulloblastoma, large-cell 31 | 6,241
ependymoma 30 | 4,679
Breast Neoplasms 28 | 445
breast carcinoma 28 | 1,638
Mammary Neoplasms 27 | 425
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
Kidney cancer 26 | 2,613
invasive ductal carcinoma 26 | 2,951
malignant mesothelioma 25 | 3,232
pancreatic cancer 25 | 2,398
Prostatic Neoplasms 24 | 495
adult high grade glioma 24 | 3,801
Adenoma 23 | 167
Colonic Neoplasms 22 | 142
diabetes mellitus 22 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
Colorectal Neoplasms 21 | 243
Vascular disease 21 | 319
lung adenocarcinoma 21 | 2,716
non-small cell lung cancer 21 | 2,890
oligodendroglioma 21 | 2,850
ulcerative colitis 21 | 1,819
Astrocytoma, Pilocytic 20 | 3,081
Neoplasm Metastasis 20 | 168
Schizophrenia 20 | 1,160
Carcinoma, Hepatocellular 19 | 228
Liver carcinoma 19 | 240
Lung Neoplasms 19 | 232
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
Squamous cell carcinoma 18 | 129
interstitial cystitis 18 | 2,312
Carcinoma, Squamous Cell 17 | 110
Kidney disease 17 | 430
Ovarian Neoplasms 17 | 102
ductal carcinoma in situ 17 | 1,745
lung carcinoma 17 | 2,843
nasopharyngeal carcinoma 17 | 1,058
primitive neuroectodermal tumor 17 | 3,035
Adenocarcinoma 16 | 122
adrenocortical carcinoma 16 | 1,428
astrocytic glioma 16 | 2,597
ovarian neoplasm 16 | 99
subependymal giant cell astrocytoma 16 | 2,287
Heart disease 15 | 306
Neoplasm Invasiveness 15 | 161
Obesity 15 | 678
Pancreatic Neoplasm 15 | 85
Pancreatic Neoplasms 15 | 85
tuberculosis 15 | 2,010
Autosomal recessive predisposition 14 | 1,442
Cell Transformation, Neoplastic 14 | 97
Familial adenomatous polyposis 14 | 32
Toxic encephalopathy 14 | 141
acute quadriplegic myopathy 14 | 1,158
group 3 medulloblastoma 14 | 4,104
juvenile dermatomyositis 14 | 1,187
Endometriosis 13 | 540
Intellectual disability 13 | 1,016
Liver disease 13 | 237
Neoplastic Cell Transformation 13 | 89
group 4 medulloblastoma 13 | 1,855
pituitary cancer 13 | 1,972
Arthritis 12 | 290
Depressive disorder 12 | 409
Epilepsy 12 | 792
Liver Neoplasms, Experimental 12 | 59
Seizures 12 | 596
Stomach cancer 12 | 30
cystic fibrosis 12 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Alzheimer's disease 11 | 658
Anemia 11 | 365
Asthma 11 | 385
Carcinoma, Non-Small-Cell Lung 11 | 107
Dull intelligence 11 | 645
Eye disease 11 | 62
Low intelligence 11 | 645
Lung disease 11 | 142
Mammary Neoplasms, Experimental 11 | 154
Melanoma 11 | 711
Mental Retardation 11 | 645
Mental deficiency 11 | 645
Poor school performance 11 | 645
Renal Cell Carcinoma 11 | 214
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
colon cancer 11 | 1,478
hepatocellular carcinoma 11 | 547
non-small cell lung carcinoma 11 | 317
Pick disease 10 | 1,894
Short stature 10 | 531

Tissue

Endocrine System 66 | 18,159
Digestive Tract 65 | 17,369
Female tissues 65 | 17,400
Male tissues 65 | 17,142
Nervous System 65 | 16,725
Skin and soft tissues 65 | 17,230
Blood and immune system 64 | 16,909
Liver and Pancreas 64 | 16,750
Urinary Tract 64 | 16,678
Respiratory system 63 | 16,393
Cardiovascular System 62 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 18 | 4,145
Kinase 12 | 634
Transcription Factor 9 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Colorectal cancer cell 68 | 68
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Epithelial cell adhesion molecule EPCAM Tbio Non-IDG -3.20358 1618.6 2244
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125
Prominin-1 PROM1 Tbio Non-IDG -3.30229 2035.0 351
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Heat-stable enterotoxin receptor GUCY2C Tclin Kinase -2.33494 214.5 228
Thymidylate synthase TYMS Tclin Enzyme -2.93426 732.0 733
TRAF2 and NCK-interacting protein kinase TNIK Tchem Kinase -1.33394 28.5 441
Cytochrome c CYCS Tbio Non-IDG -3.76637 4945.6 833