Development Level

Tbio 37 | 11,445
Tdark 3 | 6,588
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

increased or absent threshold ... 6 | 101
absent startle reflex 5 | 24
decreased body weight 4 | 161
decreased prepulse inhibition 4 | 82
decreased startle reflex 4 | 75
abnormal behavior 3 | 298
absent pinna reflex 3 | 23
decreased circulating amylase ... 3 | 28
decreased circulating triglyce... 3 | 79
increased lean body mass 3 | 172
tremors 3 | 39
trunk curl 3 | 16
abnormal bone structure 2 | 187
abnormal ear morphology 2 | 9
abnormal locomotor activation 2 | 16
abnormal locomotor behavior 2 | 24
decreased circulating glucose ... 2 | 126
decreased grip strength 2 | 116
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
impaired righting response 2 | 26
increased blood urea nitrogen ... 2 | 48
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased thermal nociceptive ... 2 | 9
increased vertical activity 2 | 24
limb grasping 2 | 41
stereotypic behavior 2 | 3
abnormal bone mineralization 1 | 38
abnormal coping response 1 | 1
abnormal digestive system phys... 1 | 1
abnormal gait 1 | 69
abnormal response to tactile s... 1 | 17
abnormal startle reflex 1 | 15
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
head bobbing 1 | 5
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
prolonged PR interval 1 | 15
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
thrombocytopenia 1 | 56

Disease

Carcinoma 33 | 11,493
Nonsyndromic deafness 28 | 142
Sensorineural hearing loss 17 | 106
psoriasis 16 | 6,694
medulloblastoma, large-cell 15 | 6,241
group 3 medulloblastoma 14 | 4,104
osteosarcoma 14 | 7,950
ovarian cancer 14 | 8,520
Autosomal recessive predisposition 13 | 1,442
Usher syndrome 12 | 32
atypical teratoid / rhabdoid tumor 12 | 5,112
Breast cancer 11 | 3,578
glioblastoma 11 | 5,792
Kidney cancer 10 | 2,613
Retinitis Pigmentosa 10 | 226
Blindness 9 | 88
adult high grade glioma 9 | 3,801
pituitary cancer 9 | 1,972
ependymoma 8 | 4,679
invasive ductal carcinoma 8 | 2,951
lung cancer 8 | 4,740
lung carcinoma 8 | 2,843
Astrocytoma, Pilocytic 7 | 3,081
Deafness 7 | 198
Intellectual disability 7 | 1,016
Melanoma 7 | 711
hearing impairment 7 | 199
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
Abnormal vision 6 | 52
Cataract 6 | 297
Difficulties with night vision 6 | 87
Dull intelligence 6 | 645
Electroretinogram abnormal 6 | 95
Hemianopsia 6 | 15
Hodgkin's lymphoma, nodular sclerosis 6 | 22
Lens Opacities 6 | 231
Liver cancer 6 | 604
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Night Blindness 6 | 101
Pigmentary iris degeneration 6 | 20
Poor school performance 6 | 645
Retinal blind spot 6 | 11
Scotoma 6 | 22
Sensorineural Hearing Loss (disorder) 6 | 284
Skin cancer 6 | 469
Usher Syndrome, Type 1 6 | 7
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
Cognitive delay 5 | 608
Congenital deafness 5 | 185
Global developmental delay 5 | 608
Hearing Loss, Partial 5 | 185
Mental and motor retardation 5 | 608
Pick disease 5 | 1,894
Schizophrenia 5 | 1,160
Usher Syndrome, Type I 5 | 6
Usher Syndrome, Type II 5 | 5
Usher syndrome type 2 5 | 5
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
group 4 medulloblastoma 5 | 1,855
non-small cell lung cancer 5 | 2,890
tuberculosis 5 | 2,010
Abnormality of cochlea 4 | 6
Cancer 4 | 2,499
Cerebellar Ataxia 4 | 304
Endometrial cancer 4 | 311
Epilepsy 4 | 792
High-grade hypermetropia 4 | 24
Prenatal onset 4 | 139
Vestibular hypofunction 4 | 7
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
malignant mesothelioma 4 | 3,232
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
Bipolar Disorder 3 | 666
Cerebellar hypoplasia and atrophy 3 | 41
Congenital hypoplasia of penis 3 | 176
Down syndrome 3 | 499
Motor delay 3 | 147
Myopia 3 | 176
No development of motor milestones 3 | 147
Perrault syndrome 3 | 19
Sensorineural hearing loss, bilateral 3 | 18
acute quadriplegic myopathy 3 | 1,158
medulloblastoma 3 | 720
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Endometriosis 2 | 540
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
nasopharyngeal carcinoma 2 | 1,058

Tissue

Endocrine System 39 | 18,159
Digestive Tract 37 | 17,369
Female tissues 37 | 17,400
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Skin and soft tissues 37 | 17,230
Urinary Tract 36 | 16,678
Liver and Pancreas 35 | 16,750
Respiratory system 33 | 16,393
Blood and immune system 32 | 16,909
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 25 | 12,091
Enzyme 5 | 4,145
Ion Channel 5 | 344
Transcription Factor 5 | 1,400
GPCR 1 | 408
Transporter 1 | 473

Jensen-TM Tissue

Cochlear hair cell 42 | 42
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
G-protein coupled receptor 98 ADGRV1 Tbio GPCR -2.51228 316.6 64
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Zinc finger protein Gfi-1 GFI1 Tbio Transcription Factor -2.20783 172.7 176
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
BarH-like 1 homeobox protein BARHL1 Tbio Transcription Factor -1.14434 12.3 108