Development Level

Tbio 31 | 10,625
Tdark 4 | 7,003
Tchem 3 | 1,890
Tclin 3 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

increased or absent threshold ... 6 | 128
absent startle reflex 5 | 15
decreased prepulse inhibition 5 | 52
decreased startle reflex 5 | 48
abnormal behavior 3 | 226
absent pinna reflex 3 | 21
decreased circulating HDL chol... 3 | 77
decreased circulating amylase ... 3 | 24
decreased circulating choleste... 3 | 85
decreased circulating glucose ... 3 | 121
decreased circulating triglyce... 3 | 83
decreased grip strength 3 | 123
increased circulating chloride... 3 | 43
trunk curl 3 | 15
abnormal bone structure 2 | 131
abnormal ear morphology 2 | 5
abnormal locomotor activation 2 | 26
decreased body length 2 | 108
decreased body weight 2 | 174
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
hyperactivity 2 | 108
impaired righting response 2 | 19
increased blood urea nitrogen ... 2 | 44
increased circulating alkaline... 2 | 119
increased circulating sodium l... 2 | 71
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
limb grasping 2 | 35
stereotypic behavior 2 | 3
abnormal bone mineralization 1 | 55
abnormal coping response 1 | 12
abnormal digestive system phys... 1 | 1
abnormal gait 1 | 51
abnormal glucose homeostasis 1 | 5
abnormal heart left ventricle ... 1 | 20
abnormal posture 1 | 5
abnormal respiratory quotient 1 | 9
abnormal response to tactile s... 1 | 16
abnormal startle reflex 1 | 14
abnormal vibrissa morphology 1 | 17
circling 1 | 1
decreased B cell number 1 | 30
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating free fat... 1 | 39
decreased circulating glycerol... 1 | 19
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased spleen weight 1 | 13
decreased vertical activity 1 | 22
embryonic lethality prior to t... 1 | 187
head bobbing 1 | 3
hypoactivity 1 | 89
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased NK T cell number 1 | 11
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased rib number 1 | 41
increased thermal nociceptive ... 1 | 9
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
preweaning lethality, complete... 1 | 633
short tibia 1 | 82
straub tail 1 | 26
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

Nonsyndromic deafness 27 | 121
psoriasis 18 | 6,685
Sensorineural hearing loss 17 | 107
medulloblastoma, large-cell 15 | 6,234
osteosarcoma 14 | 7,933
ovarian cancer 12 | 8,484
Retinitis pigmentosa 11 | 153
Usher syndrome 11 | 34
atypical teratoid / rhabdoid tumor 11 | 4,369
glioblastoma 11 | 5,572
Carcinoma 10 | 2,147
pituitary cancer 10 | 1,972
Blindness 9 | 84
lung carcinoma 9 | 2,844
pilocytic astrocytoma 9 | 3,086
Breast cancer 7 | 3,094
Hodgkin's lymphoma, nodular sclerosis 7 | 24
group 3 medulloblastoma 7 | 2,254
medulloblastoma 7 | 1,524
oligodendroglioma 7 | 2,849
primitive neuroectodermal tumor 7 | 3,031
astrocytic glioma 6 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
invasive ductal carcinoma 6 | 2,950
lung adenocarcinoma 6 | 2,713
adult high grade glioma 5 | 2,148
breast carcinoma 5 | 1,614
cystic fibrosis 5 | 1,665
ependymoma 5 | 2,514
group 4 medulloblastoma 5 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
non-small cell lung cancer 5 | 2,798
pancreatic cancer 5 | 2,300
pediatric high grade glioma 5 | 2,712
sonic hedgehog group medulloblastoma 5 | 1,482
Epilepsy 4 | 346
Pick disease 4 | 1,893
Usher Syndrome, Type II 4 | 4
Usher syndrome type 2 4 | 4
acute quadriplegic myopathy 4 | 1,157
adrenocortical carcinoma 4 | 1,427
aldosterone-producing adenoma 4 | 664
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
malignant mesothelioma 4 | 3,162
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
posterior fossa group A ependymoma 4 | 1,511
spina bifida 4 | 1,064
tuberculosis 4 | 1,557
Deafness 3 | 18
Endometriosis 3 | 535
Osteoporosis 3 | 257
atypical teratoid/rhabdoid tumor 3 | 1,095
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
lung cancer 3 | 4,466
nasopharyngeal carcinoma 3 | 1,056
posterior fossa group B ependymoma 3 | 1,530
subependymal giant cell astrocytoma 3 | 2,287
Atopic dermatitis 2 | 944
Autistic Disorder 2 | 320
Deafness, Autosomal Recessive 12 2 | 2
Down syndrome 2 | 548
Epidermodysplasia verruciformis 2 | 21
Leber congenital amaurosis 2 | 72
Macular holes 2 | 9
Multiple Sclerosis 2 | 498
Multiple myeloma 2 | 1,327
Neurodegenerative disease 2 | 383
Neuropathy 2 | 210
Obesity 2 | 616
Parkinson's disease 2 | 364
Pneumoconiosis 2 | 14
Renal Cell Carcinoma 2 | 199
Schizophrenia 2 | 501
Status Epilepticus 2 | 85
USHER SYNDROME, TYPE ID 2 | 2
USHER SYNDROME, TYPE IIA 2 | 2
USHER SYNDROME, TYPE IIC, GPR98/PDZD7, DIGENIC 2 | 2
Usher Syndrome, Type III 2 | 2
Usher syndrome, type 1D 2 | 2
Vitreous detachment 2 | 9
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
colon cancer 2 | 1,475
hearing impairment 2 | 40
interstitial lung disease 2 | 291
non primary Sjogren syndrome sicca 2 | 840
pancreatic carcinoma 2 | 567
primary pancreatic ductal adenocarcinoma 2 | 1,271
sarcoidosis 2 | 358
ulcerative colitis 2 | 2,087
Age related macular degeneration 1 | 84
Amebiasis 1 | 22
Baraitser-Winter syndrome 1 | 8
Eaton-Lambert syndrome 1 | 40
Fundus dystrophy 1 | 77
Kidney cancer 1 | 118
Myositis 1 | 24
Partial Epilepsy Treatment Adjunct 1 | 16
USHER SYNDROME, TYPE IC 1 | 1

Tissue

Digestive Tract 41 | 18,473
Endocrine System 41 | 18,512
Female tissues 41 | 18,647
Urinary Tract 41 | 18,444
Liver and Pancreas 40 | 18,136
Nervous System 40 | 18,561
Skin and soft tissues 39 | 18,115
Blood and immune system 37 | 17,995
Cardiovascular System 36 | 17,958
Male tissues 36 | 17,969
Respiratory system 35 | 17,484

Target Family

Non-IDG 22 | 11,971
Enzyme 7 | 4,146
Ion Channel 6 | 341
Transcription Factor 4 | 1,400
GPCR 1 | 406
Transporter 1 | 473

Jensen-TM Tissue

Cochlear hair cell 41 | 41
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
BarH-like 1 homeobox protein BARHL1 Tbio Transcription Factor -1.06351 11.8 78
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.02060 88.8 104
Plasma membrane calcium-transporting ATPase 2 ATP2B2 Tbio Transporter -2.03165 116.3 74
Taperin TPRN Tbio Non-IDG -0.72520 6.12 29
Harmonin USH1C Tbio Non-IDG -2.04033 115.8 173
Histidine--tRNA ligase, cytoplasmic HARS Tchem Enzyme -1.84080 63.9 190
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.81361 673.1 221
Phosphatidylinositol phosphatase PTPRQ PTPRQ Tbio Enzyme -0.99722 10.5 0
Calcium-activated potassium channel subunit alpha-1 KCNMA1 Tclin Ion Channel -3.06072 1170.6 213