Development Level

Tbio 84 | 10,625
Tchem 15 | 1,890
Tclin 3 | 602
Tdark 1 | 7,003

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 14 | 633
abnormal embryo size 6 | 112
embryonic lethality prior to t... 6 | 187
abnormal behavior 2 | 226
abnormal cornea morphology 2 | 24
abnormal forebrain development 2 | 18
abnormal hindbrain development 2 | 24
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
abnormal retina morphology 2 | 100
abnormal tail morphology 2 | 17
cleft palate 2 | 6
corneal opacity 2 | 25
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased kidney weight 2 | 7
decreased lean body mass 2 | 195
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
immune system phenotype 2 | 17
impaired pupillary reflex 2 | 14
increased bone mineral density 2 | 52
increased fasted circulating g... 2 | 68
increased mean corpuscular vol... 2 | 91
limb grasping 2 | 35
abnormal QRS complex 1 | 25
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat/ hair morphology 1 | 18
abnormal embryo turning 1 | 15
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal facial morphology 1 | 9
abnormal head morphology 1 | 10
abnormal kidney morphology 1 | 30
abnormal motor learning 1 | 4
abnormal optic disc morphology 1 | 10
abnormal retinal vasculature m... 1 | 15
abnormal skin coloration 1 | 18
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal tooth morphology 1 | 24
absent heartbeat 1 | 6
absent startle reflex 1 | 15
cataract 1 | 26
cyanosis 1 | 6
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased hematocrit 1 | 25
decreased spleen weight 1 | 13
decreased total body fat amoun... 1 | 186
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased circulating fructosa... 1 | 11
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 93
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
irregularly shaped pupil 1 | 7
mydriasis 1 | 9
narrow eye opening 1 | 15
no spontaneous movement 1 | 1
pale yolk sac 1 | 12
prenatal lethality 1 | 16
preweaning lethality, incomple... 1 | 260
small testis 1 | 37
thrombocytosis 1 | 23

Disease

ovarian cancer 52 | 8,484
Cancer 46 | 2,346
osteosarcoma 45 | 7,933
lung cancer 42 | 4,466
psoriasis 41 | 6,685
medulloblastoma, large-cell 40 | 6,234
atypical teratoid / rhabdoid tumor 30 | 4,369
glioblastoma 27 | 5,572
non-small cell lung cancer 24 | 2,798
invasive ductal carcinoma 23 | 2,950
lung adenocarcinoma 23 | 2,713
Breast cancer 21 | 3,094
Cleft palate 21 | 125
malignant mesothelioma 21 | 3,162
pilocytic astrocytoma 21 | 3,086
interstitial cystitis 20 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
lung carcinoma 18 | 2,844
oligodendroglioma 18 | 2,849
Craniofacial Abnormalities 17 | 147
ductal carcinoma in situ 17 | 1,745
Carcinoma 16 | 2,147
ependymoma 16 | 2,514
Cleft Lip 15 | 91
group 4 medulloblastoma 15 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
pediatric high grade glioma 15 | 2,712
Polydactyly 14 | 93
colon cancer 14 | 1,475
pancreatic cancer 14 | 2,300
subependymal giant cell astrocytoma 14 | 2,287
Mammary Neoplasms 13 | 410
breast carcinoma 13 | 1,614
adult high grade glioma 12 | 2,148
ulcerative colitis 12 | 2,087
Alzheimer's disease 11 | 644
Osteoporosis 11 | 257
cystic fibrosis 11 | 1,665
diabetes mellitus 11 | 1,663
group 3 medulloblastoma 11 | 2,254
primitive neuroectodermal tumor 11 | 3,031
sonic hedgehog group medulloblastoma 11 | 1,482
spina bifida 11 | 1,064
Endometriosis 10 | 535
Hypospadias 10 | 65
Pick disease 10 | 1,893
Syndactyly 10 | 56
astrocytic glioma 10 | 2,241
medulloblastoma 10 | 1,524
Kidney disease 9 | 396
Synostosis 9 | 18
adrenocortical carcinoma 9 | 1,427
astrocytoma 9 | 1,493
cutaneous lupus erythematosus 9 | 1,056
gastric carcinoma 9 | 832
pituitary cancer 9 | 1,972
posterior fossa group B ependymoma 9 | 1,530
primary pancreatic ductal adenocarcinoma 9 | 1,271
Craniosynostosis 8 | 47
Stomach Neoplasms 8 | 282
Adenoma 7 | 165
Colorectal Neoplasms 7 | 217
Holoprosencephaly 7 | 52
Intellectual disability 7 | 573
Multiple myeloma 7 | 1,327
Osteoarthritis 7 | 96
Prostatic Neoplasms 7 | 471
Rheumatoid Arthritis 7 | 1,160
Tooth agenesis 7 | 36
non primary Sjogren syndrome sicca 7 | 840
Achondroplasia 6 | 20
Acrocephalosyndactylia 6 | 15
Ankylosis 6 | 25
Atopic dermatitis 6 | 944
Limb Deformities, Congenital 6 | 16
Lung Neoplasms 6 | 171
active ulcerative colitis 6 | 477
chronic rhinosinusitis 6 | 512
esophageal adenocarcinoma 6 | 737
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
posterior fossa group A ependymoma 6 | 1,511
tuberculosis 6 | 1,557
Clubfoot 5 | 35
Colonic Neoplasms 5 | 126
Colorectal Cancer 5 | 47
Down syndrome 5 | 548
Esophageal atresia 5 | 25
Female Urogenital Diseases 5 | 18
Liver Cirrhosis 5 | 101
Lung disease 5 | 132
Melanoma 5 | 261
Pancreatic Neoplasm 5 | 79
Parkinson's disease 5 | 364
Prostate cancer 5 | 172
Pulmonary Fibrosis 5 | 66
Renal agenesis 5 | 25
acute quadriplegic myopathy 5 | 1,157
juvenile dermatomyositis 5 | 1,189
sarcoidosis 5 | 358

Tissue

Endocrine System 103 | 18,512
Female tissues 103 | 18,647
Nervous System 103 | 18,561
Skin and soft tissues 103 | 18,115
Digestive Tract 102 | 18,473
Urinary Tract 101 | 18,444
Cardiovascular System 99 | 17,958
Male tissues 99 | 17,969
Blood and immune system 96 | 17,995
Liver and Pancreas 96 | 18,136
Respiratory system 92 | 17,484

Target Family

Non-IDG 53 | 11,971
Transcription Factor 34 | 1,400
Enzyme 11 | 4,146
Kinase 4 | 634
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Bud 103 | 103
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pancreas transcription factor 1 subunit alpha PTF1A Tbio Transcription Factor -2.56282 377.5 283
Ubiquitin-conjugating enzyme E2 R1 CDC34 Tbio Non-IDG -2.08055 124.6 194
RCC1 and BTB domain-containing protein 1 RCBTB1 Tbio Non-IDG -1.74139 45.5 174
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.51373 345.1 271
Bone morphogenetic protein 2 BMP2 Tbio Non-IDG -3.59556 4267.5 575
Bone morphogenetic protein 4 BMP4 Tchem Non-IDG -3.16723 1539.5 438
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.07424 1194.2 1600
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -3.97848 10115.4 658
Short stature homeobox protein SHOX Tbio Transcription Factor -2.37649 268.5 76
Ras-related protein Rab-1A RAB1A Tbio Enzyme -2.35747 242.5 102