Development Level

Tbio 81 | 11,651
Tchem 13 | 1,388
Tclin 2 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 17 | 979
abnormal embryo size 7 | 220
embryonic lethality prior to t... 7 | 278
abnormal retina morphology 3 | 71
abnormal retinal vasculature m... 3 | 27
cataract 3 | 92
embryonic lethality prior to o... 3 | 239
enlarged heart 3 | 210
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal body wall morphology 2 | 9
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal facial morphology 2 | 17
abnormal lens morphology 2 | 81
abnormal optic disc morphology 2 | 10
abnormal retinal blood vessel ... 2 | 26
abnormal tail morphology 2 | 25
cleft palate 2 | 8
corneal opacity 2 | 32
decreased body length 2 | 101
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased circulating serum al... 2 | 82
decreased hematocrit 2 | 46
decreased lean body mass 2 | 135
decreased prepulse inhibition 2 | 82
decreased spleen weight 2 | 10
impaired pupillary reflex 2 | 26
increased body weight 2 | 25
increased bone mineral density 2 | 72
increased monocyte cell number 2 | 63
limb grasping 2 | 41
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal cranium morphology 1 | 36
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal eyelid fusion 1 | 3
abnormal head morphology 1 | 10
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal neural tube closure 1 | 46
abnormal skin appearance 1 | 3
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
absent startle reflex 1 | 24
anophthalmia 1 | 33
cyanosis 1 | 7
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
fused cornea and lens 1 | 5
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased spleen weight 1 | 10
increased total retina thickne... 1 | 4
iris synechia 1 | 3
irregularly shaped pupil 1 | 7
male infertility 1 | 123
mammalian phenotype 1 | 17
microphthalmia 1 | 26
narrow eye opening 1 | 12
pale yolk sac 1 | 25
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polydactyly 1 | 7
prenatal lethality 1 | 28
protruding tongue 1 | 3
short tibia 1 | 97
small testis 1 | 58

Disease

Carcinoma 70 | 11,493
Cancer 49 | 2,499
ovarian cancer 49 | 8,520
psoriasis 43 | 6,694
lung cancer 41 | 4,740
osteosarcoma 41 | 7,950
medulloblastoma, large-cell 38 | 6,241
atypical teratoid / rhabdoid tumor 31 | 5,112
glioblastoma 28 | 5,792
Breast cancer 27 | 3,578
ependymoma 27 | 4,679
Cleft Palate 26 | 271
non-small cell lung cancer 23 | 2,890
Kidney cancer 21 | 2,613
adult high grade glioma 21 | 3,801
malignant mesothelioma 21 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
invasive ductal carcinoma 20 | 2,951
lung adenocarcinoma 20 | 2,716
Cleft Lip 19 | 141
Short stature 19 | 531
interstitial cystitis 19 | 2,312
Astrocytoma, Pilocytic 18 | 3,081
Breast Neoplasms 18 | 445
Craniofacial Abnormalities 17 | 151
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
lung carcinoma 17 | 2,843
oligodendroglioma 17 | 2,850
Hypoplastic mandible condyle 16 | 275
Mandibular hypoplasia 16 | 275
Micrognathism 16 | 275
group 3 medulloblastoma 16 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
Polydactyly 15 | 107
astrocytic glioma 15 | 2,597
breast carcinoma 15 | 1,638
group 4 medulloblastoma 15 | 1,855
pancreatic cancer 15 | 2,398
Brachydactyly 14 | 156
Mammary Neoplasms 14 | 425
Orbital separation excessive 14 | 244
ductal carcinoma in situ 14 | 1,745
spina bifida 14 | 1,074
Intellectual disability 13 | 1,016
Uranostaphyloschisis 13 | 167
colon cancer 13 | 1,478
subependymal giant cell astrocytoma 13 | 2,287
Concave bridge of nose 12 | 195
Depressed nasal bridge 12 | 195
Depressed nasal root/bridge 12 | 195
Osteoporosis 12 | 363
Syndactyly 12 | 88
Cognitive delay 11 | 608
Decreased projection of maxilla 11 | 66
Deficiency of upper jaw bones 11 | 66
Global developmental delay 11 | 608
Hypoplasia of the maxilla 11 | 66
Hypotrophic maxilla 11 | 66
Maxillary retrognathia 11 | 66
Mental and motor retardation 11 | 608
Retrusion of upper jaw bones 11 | 66
Schizophrenia 11 | 1,160
Stomach Neoplasms 11 | 300
primitive neuroectodermal tumor 11 | 3,035
Bilateral fifth finger clinodactyly 10 | 110
Broad flat nasal bridge 10 | 236
Cryptorchidism 10 | 296
Curvature of little finger 10 | 110
Dull intelligence 10 | 645
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Nasal bridge wide 10 | 236
Pick disease 10 | 1,894
Poor school performance 10 | 645
Seizures 10 | 596
diabetes mellitus 10 | 1,728
ulcerative colitis 10 | 1,819
Alzheimer's disease 9 | 658
Autosomal recessive predisposition 9 | 1,442
Big calvaria 9 | 147
Byzanthine arch palate 9 | 194
Downward slant of palpebral fissure 9 | 158
Epilepsy 9 | 792
Frontal bossing 9 | 157
Hypotrophic malar bone 9 | 129
Increased head circumference 9 | 147
Increased size of cranium 9 | 147
Increased size of skull 9 | 147
Malar flattening 9 | 129
Osteoarthritis 9 | 184
Sensorineural Hearing Loss (disorder) 9 | 284
Strabismus 9 | 270
Tooth agenesis 9 | 44
adrenocortical carcinoma 9 | 1,428
cutaneous lupus erythematosus 9 | 1,057
cystic fibrosis 9 | 1,696
pituitary cancer 9 | 1,972
Congenital hypoplasia of penis 8 | 176
Intrauterine retardation 8 | 176

Tissue

Digestive Tract 90 | 17,369
Female tissues 90 | 17,400
Skin and soft tissues 89 | 17,230
Endocrine System 88 | 18,159
Male tissues 88 | 17,142
Urinary Tract 82 | 16,678
Liver and Pancreas 79 | 16,750
Blood and immune system 76 | 16,909
Respiratory system 75 | 16,393
Nervous System 73 | 16,725
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 50 | 12,091
Transcription Factor 35 | 1,400
Enzyme 7 | 4,145
Kinase 3 | 634
Nuclear Receptor 1 | 48

Jensen-TM Tissue

Bud 96 | 96
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyrin domain-containing protein 1 PYDC1 Tbio Non-IDG -2.88567 750.0 115
T-box transcription factor TBX18 TBX18 Tbio Transcription Factor -1.73921 54.6 183
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
Homeobox protein Hox-D10 HOXD10 Tbio Transcription Factor -1.78620 51.3 214
Exocyst complex component 1 EXOC1 Tbio Non-IDG -1.85438 74.2 51
StAR-related lipid transfer protein 13 STARD13 Tbio Non-IDG -2.03717 75.4 82
RCC1 and BTB domain-containing protein 1 RCBTB1 Tbio Non-IDG -1.76204 47.7 188
Ubiquitin-conjugating enzyme E2 R1 CDC34 Tbio Non-IDG -2.08773 125.8 222
Dual specificity protein phosphatase CDC14A CDC14A Tbio Enzyme -2.31524 216.3 245
Collagen alpha-1(II) chain COL2A1 Tbio Non-IDG -2.89229 724.4 424