Development Level

Tbio 107 | 11,445
Tchem 87 | 1,598
Tclin 36 | 613
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 22 | 979
preweaning lethality, incomple... 12 | 499
embryonic lethality prior to o... 8 | 239
embryonic lethality prior to t... 8 | 278
abnormal behavior 6 | 298
increased total body fat amoun... 6 | 134
enlarged heart 5 | 210
increased mean corpuscular hem... 5 | 96
abnormal lens morphology 4 | 81
abnormal retina morphology 4 | 71
increased circulating alkaline... 4 | 122
increased mean corpuscular vol... 4 | 92
increased startle reflex 4 | 112
abnormal bone mineralization 3 | 38
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
abnormal sleep behavior 3 | 70
cataract 3 | 92
decreased circulating LDL chol... 3 | 38
decreased circulating insulin ... 3 | 76
decreased lean body mass 3 | 135
decreased total body fat amoun... 3 | 207
edema 3 | 59
impaired righting response 3 | 26
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased circulating triglyce... 3 | 42
male infertility 3 | 123
short tibia 3 | 97
abnormal bone structure 2 | 187
abnormal cranium morphology 2 | 36
abnormal femur morphology 2 | 14
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal lung morphology 2 | 26
abnormal urinary bladder morph... 2 | 11
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased neutrophil cell numb... 2 | 42
decreased vertical activity 2 | 208
female infertility 2 | 60
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased body weight 2 | 25
increased circulating LDL chol... 2 | 13
increased hemoglobin content 2 | 45
increased lean body mass 2 | 172
increased neutrophil cell numb... 2 | 46
increased or absent threshold ... 2 | 101
microphthalmia 2 | 26
small spleen 2 | 19
small superior vagus ganglion 2 | 74
thrombocytopenia 2 | 56
thrombocytosis 2 | 27
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating creatine... 1 | 4
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating creatine... 1 | 5
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased red blood cell distr... 1 | 34
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
premature death 1 | 5
small kidney 1 | 16
thin ventricular wall 1 | 24

Disease

Cancer 220 | 2,499
ovarian cancer 168 | 8,520
Carcinoma 167 | 11,493
psoriasis 133 | 6,694
lung cancer 131 | 4,740
glioblastoma 125 | 5,792
osteosarcoma 122 | 7,950
Breast cancer 106 | 3,578
medulloblastoma, large-cell 102 | 6,241
atypical teratoid / rhabdoid tumor 101 | 5,112
Breast Neoplasms 95 | 445
Mammary Neoplasms 94 | 425
malignant mesothelioma 94 | 3,232
ependymoma 89 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 87 | 3,291
non-small cell lung cancer 79 | 2,890
pancreatic cancer 79 | 2,398
invasive ductal carcinoma 76 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 75 | 2,989
lung adenocarcinoma 75 | 2,716
diabetes mellitus 72 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 68 | 2,955
Astrocytoma, Pilocytic 65 | 3,081
ulcerative colitis 65 | 1,819
breast carcinoma 63 | 1,638
Prostatic Neoplasms 62 | 495
adult high grade glioma 62 | 3,801
ductal carcinoma in situ 60 | 1,745
group 3 medulloblastoma 59 | 4,104
primitive neuroectodermal tumor 59 | 3,035
interstitial cystitis 58 | 2,312
lung carcinoma 57 | 2,843
Vascular disease 55 | 319
adrenocortical carcinoma 55 | 1,428
Schizophrenia 54 | 1,160
oligodendroglioma 54 | 2,850
Kidney cancer 53 | 2,613
subependymal giant cell astrocytoma 52 | 2,287
tuberculosis 52 | 2,010
Neoplasm Metastasis 51 | 168
Endometriosis 48 | 540
Stomach Neoplasms 48 | 300
pituitary cancer 48 | 1,972
Carcinoma, Hepatocellular 47 | 228
Kidney disease 47 | 430
Liver carcinoma 47 | 240
Neoplasm Invasiveness 47 | 161
Obesity 46 | 678
cystic fibrosis 46 | 1,696
colon cancer 44 | 1,478
Liver Cirrhosis, Experimental 43 | 769
pancreatic ductal adenocarcinoma liver metastasis 43 | 1,962
Heart disease 41 | 306
acute quadriplegic myopathy 40 | 1,158
Arthritis 39 | 290
astrocytoma 39 | 1,146
group 4 medulloblastoma 39 | 1,855
Rheumatoid arthritis 38 | 1,191
Alzheimer's disease 37 | 658
Multiple myeloma 37 | 1,332
astrocytic glioma 37 | 2,597
pediatric high grade glioma 37 | 1,064
Adenoma 36 | 167
Lung Neoplasms 36 | 232
juvenile dermatomyositis 36 | 1,187
Hypertension 35 | 396
Liver disease 35 | 237
primary pancreatic ductal adenocarcinoma 35 | 1,109
nasopharyngeal carcinoma 34 | 1,058
Adenocarcinoma 33 | 122
Atopic dermatitis 32 | 952
Autosomal recessive predisposition 32 | 1,442
Mammary Neoplasms, Experimental 32 | 154
Squamous cell carcinoma 32 | 129
Carcinoma, Squamous Cell 31 | 110
Cell Transformation, Neoplastic 31 | 97
Bipolar Disorder 30 | 666
Colorectal Neoplasms 29 | 243
Hypertensive disease 29 | 292
Neurodegenerative disease 29 | 414
Ovarian Neoplasms 29 | 102
Pancreatic Neoplasm 29 | 85
Pancreatic Neoplasms 29 | 85
esophageal adenocarcinoma 29 | 737
Anemia 28 | 365
Colonic Neoplasms 28 | 142
Lung disease 28 | 142
Melanoma 28 | 711
Osteoporosis 28 | 363
medulloblastoma 28 | 720
ovarian neoplasm 28 | 99
Neoplastic Cell Transformation 27 | 89
Pick disease 27 | 1,894
Asthma 26 | 385
Atherosclerosis 26 | 291
Short stature 26 | 531
fibroadenoma 26 | 559
Intellectual disability 24 | 1,016
cutaneous lupus erythematosus 24 | 1,057
dermatomyositis 24 | 966

Tissue

Digestive Tract 228 | 17,369
Endocrine System 228 | 18,159
Female tissues 227 | 17,400
Liver and Pancreas 227 | 16,750
Skin and soft tissues 227 | 17,230
Urinary Tract 227 | 16,678
Male tissues 226 | 17,142
Respiratory system 226 | 16,393
Blood and immune system 225 | 16,909
Nervous System 225 | 16,725
Cardiovascular System 217 | 15,192

Target Family

Non-IDG 103 | 12,091
Enzyme 43 | 4,145
Kinase 37 | 634
Transcription Factor 34 | 1,400
Nuclear Receptor 8 | 48
Epigenetic 6 | 242
GPCR 2 | 408
Transporter 2 | 473

Jensen-TM Tissue

Breast cancer cell 235 | 235
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Breast cancer metastasis-suppressor 1-like protein BRMS1L Tbio Non-IDG -1.71309 57.0 107
ETS-related transcription factor Elf-3 ELF3 Tbio Transcription Factor -2.42034 268.3 328
Epithelial cell adhesion molecule EPCAM Tbio Non-IDG -3.20358 1618.6 2244
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Keratin, type II cytoskeletal 8 KRT8 Tbio Non-IDG -2.87670 710.7 1827
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125
Gamma-synuclein SNCG Tbio Non-IDG -2.24895 187.3 294
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492