Development Level

Tbio 233 | 11,651
Tchem 149 | 1,388
Tclin 58 | 612
Tdark 10 | 6,593

IMPC Phenotype

preweaning lethality, complete... 29 | 979
preweaning lethality, incomple... 20 | 499
embryonic lethality prior to t... 14 | 278
abnormal behavior 11 | 298
embryonic lethality prior to o... 11 | 239
abnormal embryo size 8 | 220
decreased bone mineral content 7 | 151
hypoactivity 7 | 132
increased total body fat amoun... 7 | 134
abnormal lens morphology 6 | 81
decreased vertical activity 6 | 208
enlarged heart 6 | 210
increased mean corpuscular hem... 6 | 96
abnormal bone structure 5 | 187
abnormal heart morphology 5 | 162
abnormal lung morphology 5 | 26
cataract 5 | 92
decreased circulating glucose ... 5 | 126
hyperactivity 5 | 148
increased circulating alkaline... 5 | 122
abnormal retina morphology 4 | 71
abnormal sleep behavior 4 | 70
decreased body length 4 | 101
decreased bone mineral density 4 | 126
decreased circulating HDL chol... 4 | 68
decreased circulating calcium ... 4 | 36
decreased circulating choleste... 4 | 93
decreased lean body mass 4 | 135
decreased total body fat amoun... 4 | 207
increased circulating HDL chol... 4 | 80
increased circulating choleste... 4 | 66
increased lean body mass 4 | 172
increased mean corpuscular vol... 4 | 92
increased startle reflex 4 | 112
male infertility 4 | 123
short tibia 4 | 97
abnormal bone mineralization 3 | 38
abnormal cranium morphology 3 | 36
abnormal femur morphology 3 | 14
abnormal retinal blood vessel ... 3 | 26
decreased body weight 3 | 161
decreased circulating LDL chol... 3 | 38
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased circulating triglyce... 3 | 79
decreased neutrophil cell numb... 3 | 42
decreased prepulse inhibition 3 | 82
embryonic growth retardation 3 | 106
impaired glucose tolerance 3 | 75
impaired righting response 3 | 26
increased body length 3 | 32
increased bone mineral content 3 | 108
increased circulating triglyce... 3 | 42
increased hemoglobin content 3 | 45
increased neutrophil cell numb... 3 | 46
small spleen 3 | 19
small superior vagus ganglion 3 | 74
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal humerus morphology 2 | 11
abnormal retinal vasculature m... 2 | 27
abnormal seminal vesicle morph... 2 | 114
abnormal tail morphology 2 | 25
abnormal urinary bladder morph... 2 | 11
abnormal vertebrae morphology 2 | 18
decreased T cell number 2 | 15
decreased circulating bilirubi... 2 | 19
decreased circulating creatini... 2 | 39
decreased circulating fructosa... 2 | 30
decreased circulating phosphat... 2 | 27
decreased erythrocyte cell num... 2 | 62
decreased exploration in new e... 2 | 11
decreased grip strength 2 | 116
decreased mean corpuscular vol... 2 | 79
edema 2 | 59
enlarged lymph nodes 2 | 37
female infertility 2 | 60
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased circulating LDL chol... 2 | 13
increased circulating calcium ... 2 | 34
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 76
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
microphthalmia 2 | 26
prenatal lethality prior to he... 2 | 87
prolonged QRS complex duration 2 | 8
small heart 2 | 10
small kidney 2 | 16
small testis 2 | 58
thrombocytopenia 2 | 56
thrombocytosis 2 | 27
abnormal craniofacial morpholo... 1 | 33
abnormal retinal inner nuclear... 1 | 8
decreased circulating amylase ... 1 | 28
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
thin ventricular wall 1 | 24

Disease

Cancer 409 | 2,499
Carcinoma 308 | 11,493
ovarian cancer 287 | 8,520
psoriasis 255 | 6,694
lung cancer 227 | 4,740
osteosarcoma 221 | 7,950
glioblastoma 220 | 5,792
Breast cancer 213 | 3,578
medulloblastoma, large-cell 179 | 6,241
atypical teratoid / rhabdoid tumor 172 | 5,112
malignant mesothelioma 168 | 3,232
ependymoma 160 | 4,679
Breast Neoplasms 155 | 445
Mammary Neoplasms 153 | 425
intraductal papillary-mucinous neoplasm (IPMN) 153 | 3,291
pancreatic cancer 152 | 2,398
non-small cell lung cancer 149 | 2,890
invasive ductal carcinoma 140 | 2,951
lung adenocarcinoma 138 | 2,716
diabetes mellitus 130 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 130 | 2,989
group 3 medulloblastoma 126 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 126 | 2,955
adult high grade glioma 118 | 3,801
breast carcinoma 118 | 1,638
Astrocytoma, Pilocytic 117 | 3,081
lung carcinoma 111 | 2,843
ductal carcinoma in situ 110 | 1,745
ulcerative colitis 107 | 1,819
interstitial cystitis 106 | 2,312
Schizophrenia 102 | 1,160
Prostatic Neoplasms 100 | 495
primitive neuroectodermal tumor 100 | 3,035
oligodendroglioma 95 | 2,850
Kidney cancer 94 | 2,613
tuberculosis 94 | 2,010
cystic fibrosis 93 | 1,696
subependymal giant cell astrocytoma 86 | 2,287
colon cancer 85 | 1,478
Kidney disease 84 | 430
adrenocortical carcinoma 84 | 1,428
pituitary cancer 83 | 1,972
Obesity 81 | 678
Stomach Neoplasms 80 | 300
Autosomal recessive predisposition 72 | 1,442
Heart disease 72 | 306
Vascular disease 72 | 319
astrocytic glioma 72 | 2,597
Endometriosis 71 | 540
Hypertension 71 | 396
Liver Cirrhosis, Experimental 71 | 769
Carcinoma, Hepatocellular 69 | 228
Liver carcinoma 69 | 240
Adenoma 68 | 167
nasopharyngeal carcinoma 68 | 1,058
Rheumatoid arthritis 66 | 1,191
pancreatic ductal adenocarcinoma liver metastasis 66 | 1,962
Alzheimer's disease 65 | 658
Neoplasm Metastasis 64 | 168
astrocytoma 64 | 1,146
Arthritis 62 | 290
Lung Neoplasms 62 | 232
Neoplasm Invasiveness 61 | 161
acute quadriplegic myopathy 61 | 1,158
primary pancreatic ductal adenocarcinoma 60 | 1,109
group 4 medulloblastoma 59 | 1,855
Liver disease 58 | 237
Atopic dermatitis 57 | 952
Atherosclerosis 55 | 291
Bipolar Disorder 55 | 666
Multiple myeloma 55 | 1,332
cutaneous lupus erythematosus 54 | 1,057
Anemia 53 | 365
Intellectual disability 52 | 1,016
Short stature 51 | 531
pediatric high grade glioma 51 | 1,064
Epilepsy 48 | 792
Osteoporosis 48 | 363
juvenile dermatomyositis 48 | 1,187
Asthma 47 | 385
Carcinoma, Squamous Cell 47 | 110
Coronary artery disease 47 | 268
Hypertensive disease 47 | 292
Pick disease 47 | 1,894
Squamous cell carcinoma 47 | 129
dermatomyositis 46 | 966
Cerebrovascular disease 45 | 238
Colorectal Neoplasms 45 | 243
Depressive disorder 45 | 409
Melanoma 45 | 711
esophageal adenocarcinoma 45 | 737
non-small cell lung carcinoma 45 | 317
Cell Transformation, Neoplastic 44 | 97
Ovarian Neoplasms 44 | 102
fibroadenoma 44 | 559
Dull intelligence 43 | 645
Low intelligence 43 | 645
Mental Retardation 43 | 645
Mental deficiency 43 | 645
Poor school performance 43 | 645

Tissue

Digestive Tract 433 | 17,369
Endocrine System 433 | 18,159
Skin and soft tissues 429 | 17,230
Female tissues 428 | 17,400
Male tissues 426 | 17,142
Blood and immune system 423 | 16,909
Liver and Pancreas 423 | 16,750
Urinary Tract 422 | 16,678
Respiratory system 421 | 16,393
Nervous System 413 | 16,725
Cardiovascular System 389 | 15,192

Target Family

Non-IDG 216 | 12,091
Enzyme 96 | 4,145
Kinase 54 | 634
Transcription Factor 51 | 1,400
Epigenetic 11 | 242
Nuclear Receptor 11 | 48
Transporter 6 | 473
GPCR 3 | 408
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Breast 450 | 450
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Putative uncharacterized protein encoded by MIR7-3HG MIR7-3HG Tdark Non-IDG -0.12740 2.08 0
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
C-C motif chemokine 27 CCL27 Tbio Non-IDG -2.72180 519.6 214
Secretoglobin family 1D member 2 SCGB1D2 Tbio Non-IDG -1.74277 56.9 116
Beta-casein CSN2 Tbio Enzyme -3.21413 1579.5 110
BRCA1-A complex subunit RAP80 UIMC1 Tbio Non-IDG -1.69622 52.7 176
Nuclear receptor coactivator 3 NCOA3 Tbio Epigenetic -2.64583 480.2 417