Development Level

Tbio 198 | 10,625
Tchem 170 | 1,890
Tclin 55 | 602
Tdark 6 | 7,003

IMPC Term

preweaning lethality, complete... 21 | 633
preweaning lethality, incomple... 14 | 260
embryonic lethality prior to t... 10 | 187
decreased lean body mass 9 | 195
abnormal behavior 6 | 226
abnormal embryo size 6 | 112
embryonic lethality prior to o... 6 | 148
increased mean corpuscular vol... 6 | 91
abnormal lens morphology 5 | 73
cataract 5 | 26
decreased bone mineral content 5 | 157
abnormal bone mineralization 4 | 55
decreased body length 4 | 108
decreased body weight 4 | 174
decreased bone mineral density 4 | 126
decreased circulating insulin ... 4 | 75
decreased grip strength 4 | 123
decreased total body fat amoun... 4 | 186
enlarged heart 4 | 111
increased circulating choleste... 4 | 53
increased lean body mass 4 | 107
increased mean corpuscular hem... 4 | 93
abnormal behavioral response t... 3 | 52
abnormal iris morphology 3 | 12
abnormal lung morphology 3 | 15
abnormal retina morphology 3 | 100
abnormal sleep behavior 3 | 63
decreased caudal vertebrae num... 3 | 49
decreased circulating LDL chol... 3 | 37
decreased circulating calcium ... 3 | 33
decreased rib number 3 | 59
hypoactivity 3 | 89
increased circulating HDL chol... 3 | 63
increased circulating triglyce... 3 | 24
increased grip strength 3 | 83
increased or absent threshold ... 3 | 128
increased respiratory quotient 3 | 12
increased total body fat amoun... 3 | 57
male infertility 3 | 62
abnormal QRS complex 2 | 25
abnormal bone structure 2 | 131
abnormal coat/hair pigmentatio... 2 | 54
abnormal epididymis morphology 2 | 31
abnormal femur morphology 2 | 14
abnormal forebrain development 2 | 18
abnormal head morphology 2 | 10
abnormal heart morphology 2 | 51
abnormal hindbrain development 2 | 24
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
abnormal respiratory quotient 2 | 9
abnormal retinal pigmentation 2 | 61
abnormal snout morphology 2 | 18
abnormal tooth morphology 2 | 24
decreased blood urea nitrogen ... 2 | 31
decreased circulating alkaline... 2 | 41
decreased circulating choleste... 2 | 85
decreased circulating fructosa... 2 | 31
decreased circulating glucose ... 2 | 121
decreased circulating serum al... 2 | 79
decreased heart weight 2 | 44
decreased lumbar vertebrae num... 2 | 62
decreased monocyte cell number 2 | 28
enlarged epididymis 2 | 27
enlarged lymph nodes 2 | 27
hyperactivity 2 | 108
increased circulating LDL chol... 2 | 15
increased circulating alkaline... 2 | 119
increased circulating sodium l... 2 | 71
increased sacral vertebrae num... 2 | 62
irregularly shaped pupil 2 | 7
short tibia 2 | 82
small testis 2 | 37
straub tail 2 | 26
thrombocytopenia 2 | 46
tremors 2 | 34
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal gait 1 | 51
abnormal heart left ventricle ... 1 | 20
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal retinal inner nuclear... 1 | 5
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
decreased T cell number 1 | 31
decreased circulating bilirubi... 1 | 14
decreased circulating triglyce... 1 | 83
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased pulmonary respirator... 1 | 4
decreased thoracic vertebrae n... 1 | 7
decreased total retina thickne... 1 | 20
enlarged spleen 1 | 26
female infertility 1 | 34
impaired righting response 1 | 19
increased body length 1 | 20
limb grasping 1 | 35
long tibia 1 | 13
persistence of hyaloid vascula... 1 | 22

Disease

Cancer 388 | 2,346
ovarian cancer 266 | 8,484
psoriasis 242 | 6,685
lung cancer 212 | 4,466
osteosarcoma 207 | 7,933
glioblastoma 198 | 5,572
Breast cancer 180 | 3,094
medulloblastoma, large-cell 169 | 6,234
malignant mesothelioma 154 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 148 | 3,289
pancreatic cancer 147 | 2,300
Mammary Neoplasms 145 | 410
non-small cell lung cancer 143 | 2,798
invasive ductal carcinoma 134 | 2,950
lung adenocarcinoma 134 | 2,713
atypical teratoid / rhabdoid tumor 132 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 128 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 122 | 2,956
diabetes mellitus 121 | 1,663
pediatric high grade glioma 120 | 2,712
ulcerative colitis 120 | 2,087
pilocytic astrocytoma 113 | 3,086
ductal carcinoma in situ 111 | 1,745
lung carcinoma 110 | 2,844
interstitial cystitis 105 | 2,299
breast carcinoma 100 | 1,614
Prostatic Neoplasms 97 | 471
Carcinoma 96 | 2,147
primitive neuroectodermal tumor 96 | 3,031
cystic fibrosis 90 | 1,665
oligodendroglioma 90 | 2,849
colon cancer 87 | 1,475
subependymal giant cell astrocytoma 86 | 2,287
posterior fossa group A ependymoma 84 | 1,511
pituitary cancer 82 | 1,972
tuberculosis 82 | 1,557
adrenocortical carcinoma 80 | 1,427
ependymoma 78 | 2,514
Kidney disease 77 | 396
Endometriosis 74 | 535
astrocytoma 73 | 1,493
Obesity 72 | 616
Stomach Neoplasms 72 | 282
Heart disease 66 | 279
primary pancreatic ductal adenocarcinoma 66 | 1,271
Vascular disease 65 | 281
nasopharyngeal carcinoma 64 | 1,056
Liver carcinoma 63 | 217
Rheumatoid Arthritis 63 | 1,160
acute quadriplegic myopathy 63 | 1,157
group 3 medulloblastoma 61 | 2,254
Adenoma 60 | 165
group 4 medulloblastoma 60 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 60 | 1,795
Alzheimer's disease 57 | 644
Lung Neoplasms 57 | 171
astrocytic glioma 56 | 2,241
sonic hedgehog group medulloblastoma 55 | 1,482
Arthritis 54 | 248
Atopic dermatitis 54 | 944
Hypertension 54 | 287
Multiple myeloma 54 | 1,327
cutaneous lupus erythematosus 53 | 1,056
Liver disease 52 | 219
Neoplasm Invasiveness 52 | 127
Atherosclerosis 51 | 275
Neoplasm Metastasis 51 | 138
non-small cell lung carcinoma 51 | 413
Asthma 47 | 349
juvenile dermatomyositis 47 | 1,189
medulloblastoma 46 | 1,524
Pick disease 44 | 1,893
adult high grade glioma 44 | 2,148
dermatomyositis 44 | 933
esophageal adenocarcinoma 44 | 737
gastric carcinoma 44 | 832
ovarian neoplasm 44 | 97
Coronary artery disease 43 | 240
fibroadenoma 43 | 557
atypical teratoid/rhabdoid tumor 42 | 1,095
Anemia 41 | 252
Cerebrovascular disease 41 | 231
Colorectal Neoplasms 41 | 217
Lung disease 41 | 132
Adenocarcinoma 39 | 115
Mammary Neoplasms, Experimental 38 | 150
autosomal dominant Emery-Dreifuss muscular dystrophy 38 | 499
Neoplastic Cell Transformation 37 | 81
Squamous cell carcinoma 37 | 94
Colonic Neoplasms 36 | 126
Osteoporosis 36 | 257
Pancreatic Neoplasm 36 | 79
Schizophrenia 36 | 501
Diarrhea 35 | 155
IGA Glomerulonephritis 35 | 454
Bladder Neoplasm 34 | 109
Duchenne muscular dystrophy 34 | 602
Liver Cirrhosis, Experimental 34 | 108
Peripheral Neuropathy 34 | 303
Polycystic Ovary Syndrome 34 | 332

Tissue

Endocrine System 422 | 18,512
Female tissues 421 | 18,647
Nervous System 421 | 18,561
Blood and immune system 420 | 17,995
Digestive Tract 420 | 18,473
Urinary Tract 420 | 18,444
Cardiovascular System 418 | 17,958
Skin and soft tissues 418 | 18,115
Liver and Pancreas 416 | 18,136
Male tissues 415 | 17,969
Respiratory system 415 | 17,484

Target Family

Non-IDG 207 | 11,971
Enzyme 90 | 4,146
Kinase 50 | 634
Transcription Factor 47 | 1,400
Epigenetic 11 | 242
Nuclear Receptor 11 | 48
Transporter 8 | 473
GPCR 3 | 406
Ion Channel 1 | 341
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Breast 429 | 429
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
HEAT repeat-containing protein 6 HEATR6 Tdark Non-IDG -1.48236 11.6 38
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Teratocarcinoma-derived growth factor 1 TDGF1 Tbio Non-IDG 156.3 371
E3 ubiquitin-protein ligase Mdm2 MDM2 Tchem Enzyme -3.38438 2174.7 1062