Development Level

Tbio 61 | 11,445
Tdark 10 | 6,588
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal gait 3 | 69
increased circulating alkaline... 3 | 122
abnormal behavior 2 | 298
abnormal optic disc morphology 2 | 10
corneal opacity 2 | 32
decreased body weight 2 | 161
decreased circulating glucose ... 2 | 126
decreased lean body mass 2 | 135
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
enlarged lymph nodes 2 | 37
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal QT variability 1 | 10
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal gallbladder morpholog... 1 | 1
abnormal humerus morphology 1 | 11
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal ovary morphology 1 | 7
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
cataract 1 | 92
cleft palate 1 | 8
cyanosis 1 | 7
decreased cardiac stroke volum... 1 | 6
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating free fat... 1 | 31
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased respiratory quotient 1 | 16
enlarged gallbladder 1 | 2
enlarged heart 1 | 210
enlarged ovary 1 | 2
fused cornea and lens 1 | 5
hemorrhage 1 | 23
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating glycerol... 1 | 9
increased circulating phosphat... 1 | 26
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
iris synechia 1 | 3
irregularly shaped pupil 1 | 7
limb grasping 1 | 41
long tibia 1 | 25
narrow eye opening 1 | 12
no spontaneous movement 1 | 1
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
shortened QT interval 1 | 4
small testis 1 | 58

Disease

Carcinoma 34 | 11,493
medulloblastoma, large-cell 27 | 6,241
Cleft Palate 25 | 271
psoriasis 25 | 6,694
lung cancer 23 | 4,740
osteosarcoma 22 | 7,950
Craniofacial Abnormalities 21 | 151
ovarian cancer 21 | 8,520
atypical teratoid / rhabdoid tumor 20 | 5,112
ependymoma 20 | 4,679
glioblastoma 18 | 5,792
Breast cancer 17 | 3,578
Cancer 16 | 2,499
Autosomal recessive predisposition 15 | 1,442
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
invasive ductal carcinoma 15 | 2,951
malignant mesothelioma 15 | 3,232
Astrocytoma, Pilocytic 14 | 3,081
Uranostaphyloschisis 14 | 167
group 3 medulloblastoma 14 | 4,104
Short stature 13 | 531
adult high grade glioma 13 | 3,801
oligodendroglioma 13 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Cleft Lip 11 | 141
Cognitive delay 11 | 608
Global developmental delay 11 | 608
Mental and motor retardation 11 | 608
pituitary cancer 11 | 1,972
Congenital heart disease 10 | 93
Hypoplastic mandible condyle 10 | 275
Mandibular hypoplasia 10 | 275
Micrognathism 10 | 275
Muscle hypotonia 10 | 571
Schizophrenia 10 | 1,160
cystic fibrosis 10 | 1,696
lung carcinoma 10 | 2,843
spina bifida 10 | 1,074
Congenital Heart Defects 9 | 58
Dull intelligence 9 | 645
Intellectual disability 9 | 1,016
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
Tooth agenesis 9 | 44
Velocardiofacial syndrome 9 | 46
astrocytic glioma 9 | 2,597
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
ulcerative colitis 9 | 1,819
Broad flat nasal bridge 8 | 236
DiGeorge syndrome 8 | 47
Heart Defects, Congenital 8 | 37
Low set ears 8 | 181
Nasal bridge wide 8 | 236
Polydactyly 8 | 107
Renal agenesis 8 | 29
colon cancer 8 | 1,478
ductal carcinoma in situ 8 | 1,745
group 4 medulloblastoma 8 | 1,855
interstitial cystitis 8 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Cryptorchidism 7 | 296
Epilepsy 7 | 792
Microphthalmia 7 | 76
Orbital separation excessive 7 | 244
Seizures 7 | 596
Sensorineural Hearing Loss (disorder) 7 | 284
Tetralogy of Fallot 7 | 63
breast carcinoma 7 | 1,638
lung adenocarcinoma 7 | 2,716
Concave bridge of nose 6 | 195
Conductive hearing loss 6 | 123
Congenital deafness 6 | 185
Deafness 6 | 198
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Downward slant of palpebral fissure 6 | 158
Hearing Loss, Partial 6 | 185
Highly variable severity 6 | 157
Holoprosencephaly 6 | 56
Hypospadias 6 | 53
Hypotrophic malar bone 6 | 129
Long face 6 | 71
Malar flattening 6 | 129
Obesity 6 | 678
Small head 6 | 374
Synostosis 6 | 15
Thin hypoplastic alae nasi 6 | 51
Variable expressivity 6 | 157
hearing impairment 6 | 199
primitive neuroectodermal tumor 6 | 3,035
Bipolar Disorder 5 | 666
Byzanthine arch palate 5 | 194
Curvature of spine 5 | 282
Kidney cancer 5 | 2,613
Pick disease 5 | 1,894
Ventricular Septal Defects 5 | 119

Tissue

Endocrine System 68 | 18,159
Digestive Tract 66 | 17,369
Skin and soft tissues 64 | 17,230
Female tissues 62 | 17,400
Male tissues 62 | 17,142
Blood and immune system 59 | 16,909
Urinary Tract 58 | 16,678
Liver and Pancreas 56 | 16,750
Nervous System 55 | 16,725
Respiratory system 54 | 16,393
Cardiovascular System 50 | 15,192

Target Family

Transcription Factor 45 | 1,400
Non-IDG 25 | 12,091
Enzyme 4 | 4,145
GPCR 1 | 408

Jensen-TM Tissue

Branchial arch 75 | 75
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein Nkx-2.6 NKX2-6 Tbio Transcription Factor -3.04651 1092.2 134
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Homeobox protein BarH-like 1 BARX1 Tbio Transcription Factor -1.51202 31.9 202
Cellular retinoic acid-binding protein 1 CRABP1 Tbio Non-IDG -2.48395 306.2 152
Zinc finger HIT domain-containing protein 2 ZNHIT2 Tdark Non-IDG -1.72886 50.7 46
Cryptic family protein 1B CFC1B Tdark Non-IDG 0.35 0.34 45
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Homeobox protein Hox-A2 HOXA2 Tbio Transcription Factor -2.29353 198.5 99
Homeobox protein Hox-A3 HOXA3 Tbio Transcription Factor -1.65690 45.4 164
Retinal dehydrogenase 2 ALDH1A2 Tbio Enzyme -2.25078 175.3 229