Development Level

Tbio 790 | 10,625
Tchem 420 | 1,890
Tclin 215 | 602
Tdark 17 | 7,003

Collection

Eligible Ion Channel Proteins 7 | 117
Eligible non-olfactory GPCR Proteins 7 | 143

IMPC Term

preweaning lethality, complete... 61 | 633
preweaning lethality, incomple... 38 | 260
abnormal behavior 33 | 226
decreased lean body mass 26 | 195
decreased bone mineral content 24 | 157
embryonic lethality prior to t... 24 | 187
decreased total body fat amoun... 22 | 186
increased circulating alkaline... 20 | 119
decreased body weight 19 | 174
decreased grip strength 19 | 123
hyperactivity 19 | 108
abnormal bone structure 18 | 131
abnormal embryo size 17 | 112
hypoactivity 16 | 89
increased grip strength 15 | 83
decreased bone mineral density 14 | 126
decreased circulating choleste... 14 | 85
embryonic lethality prior to o... 14 | 148
increased or absent threshold ... 14 | 128
decreased circulating HDL chol... 13 | 77
increased lean body mass 13 | 107
decreased fasted circulating g... 12 | 49
enlarged heart 12 | 111
improved glucose tolerance 12 | 56
increased circulating HDL chol... 12 | 63
increased mean corpuscular vol... 12 | 91
abnormal gait 11 | 51
decreased body length 10 | 108
decreased circulating LDL chol... 10 | 37
decreased circulating alanine ... 10 | 53
decreased circulating insulin ... 10 | 75
decreased circulating triglyce... 10 | 83
increased total body fat amoun... 10 | 57
male infertility 10 | 62
abnormal neural tube closure 9 | 37
abnormal retina morphology 9 | 100
abnormal sleep behavior 9 | 63
decreased heart weight 9 | 44
decreased mean corpuscular vol... 9 | 50
decreased prepulse inhibition 9 | 52
impaired glucose tolerance 9 | 52
increased circulating chloride... 9 | 43
increased circulating choleste... 9 | 53
short tibia 9 | 82
abnormal epididymis morphology 8 | 31
increased mean corpuscular hem... 8 | 93
tremors 8 | 34
abnormal bone mineralization 7 | 55
cataract 7 | 26
decreased circulating alkaline... 7 | 41
decreased circulating calcium ... 7 | 33
decreased circulating glucose ... 7 | 121
female infertility 7 | 34
increased blood urea nitrogen ... 7 | 44
increased body weight 7 | 42
increased bone mineral density 7 | 52
increased circulating sodium l... 7 | 71
increased fasted circulating g... 7 | 68
limb grasping 7 | 35
abnormal QRS complex 6 | 25
abnormal behavioral response t... 6 | 52
abnormal forebrain development 6 | 18
abnormal hindbrain development 6 | 24
abnormal lens morphology 6 | 73
abnormal retinal pigmentation 6 | 61
decreased circulating serum al... 6 | 79
decreased circulating total pr... 6 | 41
decreased rib number 6 | 59
decreased startle reflex 6 | 48
decreased vertical activity 6 | 22
enlarged epididymis 6 | 27
increased bone mineral content 6 | 92
increased circulating potassiu... 6 | 31
increased erythrocyte cell num... 6 | 26
increased startle reflex 6 | 38
thrombocytopenia 6 | 46
abnormal coat/hair pigmentatio... 5 | 54
abnormal heart morphology 5 | 51
abnormal midbrain development 5 | 22
abnormal testis morphology 5 | 30
cardiovascular system phenotyp... 5 | 35
decreased blood urea nitrogen ... 5 | 31
decreased circulating amylase ... 5 | 24
decreased circulating aspartat... 5 | 27
decreased leukocyte cell numbe... 5 | 54
decreased mean corpuscular hem... 5 | 34
increased circulating creatini... 5 | 29
increased circulating phosphat... 5 | 24
small testis 5 | 37
straub tail 5 | 26
abnormal locomotor activation 4 | 26
abnormal tooth morphology 4 | 24
corneal opacity 4 | 25
decreased T cell number 4 | 31
decreased hemoglobin content 4 | 53
decreased total retina thickne... 4 | 20
increased circulating calcium ... 4 | 32
increased circulating serum al... 4 | 25
increased heart weight 4 | 37
persistence of hyaloid vascula... 4 | 22

Disease

ovarian cancer 721 | 8,484
psoriasis 692 | 6,685
medulloblastoma, large-cell 678 | 6,234
glioblastoma 676 | 5,572
Cancer 631 | 2,346
osteosarcoma 629 | 7,933
lung cancer 550 | 4,466
atypical teratoid / rhabdoid tumor 497 | 4,369
pilocytic astrocytoma 468 | 3,086
oligodendroglioma 435 | 2,849
malignant mesothelioma 377 | 3,162
lung carcinoma 375 | 2,844
primitive neuroectodermal tumor 375 | 3,031
pediatric high grade glioma 366 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 337 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 328 | 2,956
invasive ductal carcinoma 328 | 2,950
Breast cancer 320 | 3,094
diabetes mellitus 316 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 313 | 2,988
subependymal giant cell astrocytoma 307 | 2,287
ependymoma 303 | 2,514
Carcinoma 300 | 2,147
lung adenocarcinoma 290 | 2,713
non-small cell lung cancer 289 | 2,798
interstitial cystitis 276 | 2,299
astrocytic glioma 271 | 2,241
pancreatic cancer 271 | 2,300
ulcerative colitis 271 | 2,087
pituitary cancer 259 | 1,972
astrocytoma 251 | 1,493
Alzheimer's disease 242 | 644
adult high grade glioma 239 | 2,148
cystic fibrosis 232 | 1,665
Pick disease 225 | 1,893
group 4 medulloblastoma 219 | 1,875
Schizophrenia 214 | 501
medulloblastoma 213 | 1,524
colon cancer 208 | 1,475
Obesity 206 | 616
breast carcinoma 206 | 1,614
posterior fossa group A ependymoma 205 | 1,511
ductal carcinoma in situ 199 | 1,745
tuberculosis 191 | 1,557
group 3 medulloblastoma 188 | 2,254
Epilepsy 185 | 346
adrenocortical carcinoma 174 | 1,427
Kidney disease 173 | 396
Neurodegenerative disease 173 | 383
pancreatic ductal adenocarcinoma liver metastasis 173 | 1,795
Parkinson's disease 169 | 364
sonic hedgehog group medulloblastoma 166 | 1,482
Vascular disease 163 | 281
Rheumatoid Arthritis 162 | 1,160
Autistic Disorder 159 | 320
Hypertension 159 | 287
atypical teratoid/rhabdoid tumor 157 | 1,095
posterior fossa group B ependymoma 157 | 1,530
Cerebrovascular disease 153 | 231
cutaneous lupus erythematosus 151 | 1,056
primary pancreatic ductal adenocarcinoma 149 | 1,271
Heart disease 146 | 279
Intellectual disability 144 | 573
Multiple myeloma 138 | 1,327
Mammary Neoplasms 137 | 410
acute quadriplegic myopathy 133 | 1,157
juvenile dermatomyositis 127 | 1,189
Prostatic Neoplasms 126 | 471
Down syndrome 124 | 548
Asthma 121 | 349
Atherosclerosis 121 | 275
Multiple Sclerosis 121 | 498
Toxic encephalopathy 118 | 131
gastric carcinoma 117 | 832
dermatomyositis 115 | 933
Coronary artery disease 109 | 240
Bipolar Disorder 108 | 266
Arthritis 106 | 248
Atopic dermatitis 106 | 944
Dementia 105 | 129
Duchenne muscular dystrophy 104 | 602
Endometriosis 103 | 535
Waldenstrons macroglobulinemia 98 | 765
nasopharyngeal carcinoma 94 | 1,056
Hypertensive disease 92 | 193
Amyotrophic Lateral Sclerosis 86 | 431
Liver disease 86 | 219
spina bifida 86 | 1,064
Lung disease 85 | 132
aldosterone-producing adenoma 85 | 664
Liver carcinoma 84 | 217
Neuropathy 84 | 210
esophageal adenocarcinoma 84 | 737
Stomach Neoplasms 82 | 282
active Crohn's disease 82 | 918
fibroadenoma 78 | 557
Adenoma 77 | 165
autosomal dominant Emery-Dreifuss muscular dystrophy 77 | 499
non primary Sjogren syndrome sicca 77 | 840
Hypersensitivity reaction type II disease 76 | 235

Tissue

Nervous System 1,429 | 18,561
Endocrine System 1,426 | 18,512
Female tissues 1,424 | 18,647
Digestive Tract 1,422 | 18,473
Urinary Tract 1,416 | 18,444
Skin and soft tissues 1,407 | 18,115
Liver and Pancreas 1,406 | 18,136
Cardiovascular System 1,401 | 17,958
Blood and immune system 1,390 | 17,995
Male tissues 1,387 | 17,969
Respiratory system 1,366 | 17,484

Target Family

Non-IDG 644 | 11,971
Enzyme 310 | 4,146
Transcription Factor 115 | 1,400
GPCR 103 | 406
Ion Channel 90 | 341
Kinase 89 | 634
Transporter 57 | 473
Epigenetic 16 | 242
Nuclear Receptor 16 | 48
TF/Epigenetic 2 | 38

Jensen-TM Tissue

Brain 1,442 | 1,442
Blood 1,867 | 1,867
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.31593 2169.0 108
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Retinaldehyde-binding protein 1 RLBP1 Tbio Non-IDG -2.12314 137.8 95
Achaete-scute homolog 1 ASCL1 Tbio Transcription Factor -2.39907 258.0 359
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628