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Development Level

Tbio 922 | 11,651
Tchem 355 | 1,388
Tclin 228 | 612
Tdark 11 | 6,593

Collection

RFA-RM-18-021 8 | 328
GPCR: IDG Consortium (Targets) 6 | 126
Ion Channel: IDG Consortium (T... 5 | 99
GPCR: IDG Consortium (Complete... 4 | 25
Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 94 | 979
preweaning lethality, incomple... 63 | 499
abnormal behavior 44 | 298
embryonic lethality prior to t... 33 | 278
decreased total body fat amoun... 29 | 207
hyperactivity 29 | 148
decreased vertical activity 26 | 208
abnormal embryo size 25 | 220
decreased bone mineral content 25 | 151
embryonic lethality prior to o... 25 | 239
increased total body fat amoun... 25 | 134
enlarged heart 24 | 210
increased circulating alkaline... 24 | 122
increased lean body mass 24 | 172
abnormal bone structure 23 | 187
decreased lean body mass 22 | 135
hypoactivity 21 | 132
decreased body weight 20 | 161
improved glucose tolerance 17 | 79
abnormal gait 16 | 69
abnormal heart morphology 16 | 162
decreased grip strength 16 | 116
prolonged QT interval 16 | 38
prolonged ST segment 16 | 36
cataract 15 | 92
decreased circulating choleste... 15 | 93
embryonic growth retardation 15 | 106
increased mean corpuscular vol... 15 | 92
abnormal seminal vesicle morph... 14 | 114
decreased prepulse inhibition 14 | 82
increased bone mineral content 14 | 108
short tibia 14 | 97
abnormal retina morphology 13 | 71
abnormal lens morphology 12 | 81
decreased body length 12 | 101
decreased bone mineral density 12 | 126
decreased circulating HDL chol... 12 | 68
decreased fasted circulating g... 12 | 65
impaired glucose tolerance 12 | 75
increased circulating HDL chol... 12 | 80
increased circulating choleste... 12 | 66
increased fasted circulating g... 12 | 76
increased startle reflex 12 | 112
male infertility 12 | 123
abnormal sleep behavior 11 | 70
decreased circulating serum al... 11 | 82
decreased lymphocyte cell numb... 11 | 83
decreased mean corpuscular vol... 11 | 79
limb grasping 11 | 41
decreased circulating glucose ... 10 | 126
decreased startle reflex 10 | 75
increased circulating chloride... 10 | 41
small superior vagus ganglion 10 | 74
abnormal epididymis morphology 9 | 42
decreased circulating LDL chol... 9 | 38
decreased circulating alkaline... 9 | 46
decreased circulating triglyce... 9 | 79
increased circulating sodium l... 9 | 71
increased monocyte cell number 9 | 63
abnormal behavioral response t... 8 | 66
decreased circulating alanine ... 8 | 47
decreased circulating aspartat... 8 | 34
decreased circulating calcium ... 8 | 36
decreased circulating insulin ... 8 | 76
decreased circulating total pr... 8 | 49
decreased erythrocyte cell num... 8 | 62
decreased mean corpuscular hem... 8 | 50
increased circulating triglyce... 8 | 42
thrombocytopenia 8 | 56
abnormal locomotor behavior 7 | 24
abnormal testis morphology 7 | 43
cardiovascular system phenotyp... 7 | 36
decreased circulating amylase ... 7 | 28
decreased heart weight 7 | 27
decreased leukocyte cell numbe... 7 | 73
decreased neutrophil cell numb... 7 | 42
female infertility 7 | 60
increased circulating iron lev... 7 | 30
increased erythrocyte cell num... 7 | 39
increased grip strength 7 | 41
increased mean corpuscular hem... 7 | 96
increased neutrophil cell numb... 7 | 46
small testis 7 | 58
tremors 7 | 39
abnormal bone mineralization 6 | 38
abnormal cranium morphology 6 | 36
abnormal kidney morphology 6 | 65
abnormal lung morphology 6 | 26
corneal opacity 6 | 32
decreased blood urea nitrogen ... 6 | 51
decreased circulating phosphat... 6 | 27
decreased hemoglobin content 6 | 68
decreased red blood cell distr... 6 | 41
edema 6 | 59
increased bone mineral density 6 | 72
increased circulating phosphat... 6 | 26
increased circulating total pr... 6 | 28
increased heart weight 6 | 62
increased mean platelet volume 6 | 45
thin ventricular wall 6 | 24

Disease

Carcinoma 1,052 | 11,493
ovarian cancer 762 | 8,520
glioblastoma 745 | 5,792
psoriasis 728 | 6,694
medulloblastoma, large-cell 720 | 6,241
Cancer 686 | 2,499
osteosarcoma 666 | 7,950
atypical teratoid / rhabdoid tumor 635 | 5,112
lung cancer 616 | 4,740
ependymoma 613 | 4,679
adult high grade glioma 510 | 3,801
Astrocytoma, Pilocytic 487 | 3,081
Schizophrenia 485 | 1,160
group 3 medulloblastoma 461 | 4,104
oligodendroglioma 453 | 2,850
malignant mesothelioma 416 | 3,232
Breast cancer 411 | 3,578
primitive neuroectodermal tumor 395 | 3,035
lung carcinoma 389 | 2,843
astrocytic glioma 375 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 357 | 3,291
invasive ductal carcinoma 354 | 2,951
diabetes mellitus 350 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 350 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 332 | 2,989
Kidney cancer 329 | 2,613
non-small cell lung cancer 323 | 2,890
lung adenocarcinoma 320 | 2,716
subependymal giant cell astrocytoma 320 | 2,287
Bipolar Disorder 301 | 666
pancreatic cancer 301 | 2,398
Epilepsy 296 | 792
interstitial cystitis 291 | 2,312
pituitary cancer 277 | 1,972
Depressive disorder 261 | 409
Alzheimer's disease 260 | 658
cystic fibrosis 247 | 1,696
ulcerative colitis 246 | 1,819
Autosomal recessive predisposition 243 | 1,442
Obesity 239 | 678
tuberculosis 238 | 2,010
Intellectual disability 235 | 1,016
Pick disease 235 | 1,894
breast carcinoma 229 | 1,638
Seizures 227 | 596
colon cancer 224 | 1,478
group 4 medulloblastoma 222 | 1,855
Hypertension 221 | 396
ductal carcinoma in situ 212 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 208 | 1,962
Mental Depression 194 | 333
Neurodegenerative disease 189 | 414
Kidney disease 188 | 430
adrenocortical carcinoma 186 | 1,428
Vascular disease 184 | 319
astrocytoma 182 | 1,146
Parkinson's disease 181 | 392
Autistic Disorder 178 | 364
Rheumatoid arthritis 170 | 1,191
Major Depressive Disorder 169 | 301
Heart disease 165 | 306
Dull intelligence 162 | 645
Low intelligence 162 | 645
Mental Retardation 162 | 645
Mental deficiency 162 | 645
Poor school performance 162 | 645
Alcoholic Intoxication, Chronic 160 | 289
cutaneous lupus erythematosus 159 | 1,057
Cerebrovascular disease 158 | 238
Liver Cirrhosis, Experimental 153 | 769
Breast Neoplasms 152 | 445
Multiple myeloma 149 | 1,332
Mammary Neoplasms 148 | 425
Cognitive delay 144 | 608
Global developmental delay 144 | 608
Mental and motor retardation 144 | 608
acute quadriplegic myopathy 141 | 1,158
Unipolar Depression 140 | 250
Melanoma 135 | 711
Prostatic Neoplasms 135 | 495
Multiple Sclerosis 134 | 540
Atherosclerosis 132 | 291
Down syndrome 132 | 499
Muscle hypotonia 132 | 571
Asthma 131 | 385
Dementia 130 | 175
juvenile dermatomyositis 130 | 1,187
primary pancreatic ductal adenocarcinoma 129 | 1,109
Mood Disorders 128 | 184
Toxic encephalopathy 128 | 141
Hypertensive disease 127 | 292
pediatric high grade glioma 124 | 1,064
dermatomyositis 123 | 966
Arthritis 119 | 290
Coronary artery disease 119 | 268
gastric carcinoma 115 | 807
Atopic dermatitis 114 | 952
Duchenne muscular dystrophy 109 | 601
Endometriosis 107 | 540
Short stature 106 | 531

Tissue

Endocrine System 1,467 | 18,159
Digestive Tract 1,426 | 17,369
Nervous System 1,419 | 16,725
Female tissues 1,418 | 17,400
Skin and soft tissues 1,409 | 17,230
Male tissues 1,378 | 17,142
Liver and Pancreas 1,364 | 16,750
Blood and immune system 1,359 | 16,909
Urinary Tract 1,356 | 16,678
Respiratory system 1,321 | 16,393
Cardiovascular System 1,225 | 15,192

Target Family

Non-IDG 683 | 12,091
Enzyme 319 | 4,145
Transcription Factor 124 | 1,400
GPCR 105 | 408
Kinase 94 | 634
Ion Channel 93 | 344
Transporter 60 | 473
Epigenetic 19 | 242
Nuclear Receptor 17 | 48
TF/Epigenetic 2 | 38

Jensen-TM Tissue

Brain 1,516 | 1,516
Blood 1,962 | 1,962
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Relaxin-3 RLN3 Tbio Non-IDG -1.88808 92.6 93
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275