Development Level

Tbio 307 | 11,178
Tchem 128 | 1,885
Tclin 76 | 612
Tdark 2 | 6,569

IMPC Phenotype

preweaning lethality, complete... 23 | 979
preweaning lethality, incomple... 13 | 499
embryonic lethality prior to t... 10 | 278
abnormal seminal vesicle morph... 9 | 114
decreased vertical activity 9 | 208
enlarged heart 9 | 210
small superior vagus ganglion 7 | 74
abnormal embryo size 6 | 220
abnormal heart morphology 6 | 162
decreased body weight 6 | 161
decreased erythrocyte cell num... 6 | 62
decreased hemoglobin content 6 | 68
increased total body fat amoun... 6 | 134
embryonic lethality prior to o... 5 | 239
increased blood urea nitrogen ... 5 | 48
increased mean corpuscular vol... 5 | 92
increased monocyte cell number 5 | 63
limb grasping 5 | 41
abnormal gait 4 | 69
decreased bone mineral content 4 | 151
decreased hematocrit 4 | 46
decreased leukocyte cell numbe... 4 | 73
decreased lymphocyte cell numb... 4 | 83
embryonic growth retardation 4 | 106
hydrometra 4 | 53
impaired glucose tolerance 4 | 75
increased circulating HDL chol... 4 | 80
increased lymphocyte cell numb... 4 | 32
increased mean corpuscular hem... 4 | 96
increased neutrophil cell numb... 4 | 46
increased startle reflex 4 | 112
thrombocytopenia 4 | 56
abnormal lens morphology 3 | 81
abnormal spleen morphology 3 | 55
abnormal startle reflex 3 | 15
abnormal testis morphology 3 | 43
cataract 3 | 92
decreased bone mineral density 3 | 126
decreased circulating creatini... 3 | 39
decreased circulating glucose ... 3 | 126
decreased heart weight 3 | 27
decreased lean body mass 3 | 135
decreased mean corpuscular vol... 3 | 79
decreased prepulse inhibition 3 | 82
enlarged lymph nodes 3 | 37
increased bone mineral content 3 | 108
increased bone mineral density 3 | 72
increased circulating choleste... 3 | 66
increased circulating triglyce... 3 | 42
increased lean body mass 3 | 172
prenatal lethality prior to he... 3 | 87
short tibia 3 | 97
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal epididymis morphology 2 | 42
abnormal femur morphology 2 | 14
abnormal head morphology 2 | 10
abnormal humerus morphology 2 | 11
abnormal locomotor activation 2 | 16
abnormal lung morphology 2 | 26
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
abnormal tooth morphology 2 | 24
abnormal vertebrae morphology 2 | 18
corneal opacity 2 | 32
decreased body length 2 | 101
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased fasted circulating g... 2 | 65
decreased large unstained cell... 2 | 11
decreased neutrophil cell numb... 2 | 42
edema 2 | 59
enlarged spleen 2 | 41
enlarged uterus 2 | 11
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased circulating LDL chol... 2 | 13
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating iron lev... 2 | 30
increased eosinophil cell numb... 2 | 11
increased grip strength 2 | 41
increased leukocyte cell numbe... 2 | 47
increased spleen weight 2 | 10
small testis 2 | 58
tremors 2 | 39
abnormal cornea morphology 1 | 31
abnormal retina morphology 1 | 71
abnormal whole-body plethysmog... 1 | 4
decreased T cell number 1 | 15
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased mean corpuscular hem... 1 | 31
impaired pupillary reflex 1 | 26
increased blood uric acid leve... 1 | 5
increased cardiac muscle contr... 1 | 8
increased heart weight 1 | 62
microphthalmia 1 | 26

Disease

Cancer 444 | 2,388
Carcinoma 301 | 11,192
psoriasis 278 | 6,514
osteosarcoma 238 | 7,766
ovarian cancer 219 | 8,297
lung cancer 213 | 4,607
diabetes mellitus 195 | 1,683
glioblastoma 194 | 5,635
Arthritis 172 | 276
tuberculosis 167 | 1,963
Hypersensitivity reaction type II disease 164 | 245
medulloblastoma, large-cell 156 | 6,086
interstitial cystitis 152 | 2,237
Breast cancer 146 | 3,469
Rheumatoid arthritis 144 | 1,156
lung carcinoma 143 | 2,755
malignant mesothelioma 142 | 3,135
invasive ductal carcinoma 137 | 2,867
Anemia 128 | 353
ulcerative colitis 128 | 1,765
lung adenocarcinoma 127 | 2,627
non-small cell lung cancer 127 | 2,799
Kidney disease 126 | 411
adult high grade glioma 123 | 3,701
Astrocytoma, Pilocytic 120 | 3,006
Multiple Sclerosis 118 | 527
atypical teratoid / rhabdoid tumor 114 | 4,971
intraductal papillary-mucinous adenoma (IPMA) 114 | 2,872
ependymoma 113 | 4,559
pancreatic cancer 113 | 2,322
intraductal papillary-mucinous carcinoma (IPMC) 111 | 2,902
intraductal papillary-mucinous neoplasm (IPMN) 111 | 3,204
Human immunodeficiency virus infectious disease 103 | 136
Liver disease 98 | 227
cutaneous lupus erythematosus 96 | 1,016
Asthma 91 | 370
Ankylosing spondylitis 90 | 134
Schizophrenia 90 | 1,136
Acquired immunodeficiency syndrome 89 | 192
Dermatitis 88 | 154
breast carcinoma 87 | 1,589
group 3 medulloblastoma 85 | 4,002
subependymal giant cell astrocytoma 84 | 2,230
ductal carcinoma in situ 82 | 1,686
cystic fibrosis 81 | 1,629
Kidney cancer 79 | 2,548
dermatomyositis 79 | 941
Autosomal recessive predisposition 78 | 1,407
Inflammatory bowel disease 77 | 148
Uveitis 77 | 102
Liver Cirrhosis, Experimental 75 | 733
oligodendroglioma 75 | 2,768
Atherosclerosis 73 | 276
Lung disease 73 | 135
Breast Neoplasms 72 | 423
Vascular disease 72 | 294
pituitary cancer 72 | 1,915
Behcet's disease 71 | 87
Mammary Neoplasms 71 | 403
Juvenile rheumatoid arthritis 70 | 110
Thrombocytopenia 69 | 193
astrocytic glioma 69 | 2,530
primitive neuroectodermal tumor 69 | 2,957
Heart disease 67 | 288
Herpes zoster 63 | 68
Obesity 63 | 655
group 4 medulloblastoma 63 | 1,806
Coronary artery disease 62 | 253
primary Sjogren syndrome 62 | 710
Psoriatic arthritis 61 | 84
colon cancer 60 | 1,428
Hypertension 59 | 372
Stevens-Johnson syndrome 59 | 92
nasopharyngeal carcinoma 59 | 1,024
Pneumonia 58 | 169
Melanoma 57 | 689
Osteoporosis 57 | 348
Diarrhea 56 | 245
Hepatitis B 56 | 105
Synovitis 56 | 75
periodontitis 56 | 280
Multiple myeloma 55 | 1,296
juvenile dermatomyositis 55 | 1,147
sarcoidosis 54 | 357
Alzheimer's disease 53 | 640
Cerebrovascular disease 53 | 223
Allergic hypersensitivity disease 52 | 124
Prostatic Neoplasms 52 | 472
Short stature 52 | 514
pancreatic ductal adenocarcinoma liver metastasis 51 | 1,911
primary pancreatic ductal adenocarcinoma 51 | 1,071
Splenomegaly 50 | 186
Atopic dermatitis 49 | 915
Inflammation 49 | 116
Lung Neoplasms 48 | 217
Malaria 47 | 155
Stomach Neoplasms 46 | 287
adrenocortical carcinoma 46 | 1,385
astrocytoma 46 | 1,113
Hypertensive disease 45 | 278

Tissue

Endocrine System 425 | 18,159
Blood and immune system 422 | 16,909
Digestive Tract 422 | 17,369
Skin and soft tissues 420 | 17,230
Female tissues 419 | 17,400
Liver and Pancreas 417 | 16,750
Male tissues 417 | 17,142
Urinary Tract 416 | 16,678
Respiratory system 412 | 16,393
Nervous System 404 | 16,725
Cardiovascular System 380 | 15,192

Target Family

Non-IDG 336 | 12,091
Enzyme 65 | 4,145
Transcription Factor 50 | 1,400
Kinase 33 | 634
GPCR 16 | 408
Epigenetic 6 | 242
Nuclear Receptor 3 | 48
Transporter 2 | 473
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Bone marrow 513 | 513
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Histone H2B type 2-E HIST2H2BE Tbio Non-IDG -3.48425 2920.0 135
T-lymphocyte activation antigen CD80 CD80 Tclin Non-IDG -3.39216 2405.6 1323
Bone sialoprotein 2 IBSP Tbio Non-IDG -2.95483 756.8 261
HLA class I histocompatibility antigen, B-67 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 362
Tumor necrosis factor receptor superfamily member 1B TNFRSF1B Tchem Non-IDG -3.67481 4484.7 712
Wilms tumor protein WT1 Tbio Transcription Factor -3.48344 3138.9 571
Histone-lysine N-methyltransferase 2A KMT2A Tchem Epigenetic -2.88228 736.0 334
Macrophage colony-stimulating factor 1 receptor CSF1R Tclin Kinase -3.19109 1432.9 1169
Homeobox protein NANOG NANOG Tchem Transcription Factor -2.94914 1130.5 958