Development Level

Tbio 230 | 11,651
Tchem 107 | 1,388
Tclin 57 | 612
Tdark 4 | 6,593

IMPC Phenotype

preweaning lethality, complete... 27 | 979
embryonic lethality prior to t... 15 | 278
preweaning lethality, incomple... 13 | 499
embryonic lethality prior to o... 11 | 239
decreased vertical activity 10 | 208
enlarged heart 9 | 210
abnormal behavior 7 | 298
abnormal embryo size 7 | 220
increased total body fat amoun... 7 | 134
abnormal heart morphology 6 | 162
decreased body weight 6 | 161
increased mean corpuscular vol... 6 | 92
increased neutrophil cell numb... 6 | 46
male infertility 6 | 123
abnormal lung morphology 5 | 26
abnormal seminal vesicle morph... 5 | 114
decreased bone mineral content 5 | 151
decreased circulating creatini... 5 | 39
decreased lean body mass 5 | 135
embryonic growth retardation 5 | 106
thrombocytopenia 5 | 56
abnormal retina morphology 4 | 71
abnormal sleep behavior 4 | 70
decreased bone mineral density 4 | 126
decreased lymphocyte cell numb... 4 | 83
hyperactivity 4 | 148
hypoactivity 4 | 132
increased circulating alkaline... 4 | 122
increased circulating calcium ... 4 | 34
increased lymphocyte cell numb... 4 | 32
increased mean corpuscular hem... 4 | 96
increased monocyte cell number 4 | 63
abnormal behavioral response t... 3 | 66
abnormal bone structure 3 | 187
abnormal eye morphology 3 | 68
abnormal gait 3 | 69
abnormal lens morphology 3 | 81
abnormal testis morphology 3 | 43
cataract 3 | 92
decreased blood urea nitrogen ... 3 | 51
decreased body length 3 | 101
decreased circulating serum al... 3 | 82
decreased circulating triglyce... 3 | 79
decreased erythrocyte cell num... 3 | 62
decreased fasted circulating g... 3 | 65
decreased heart weight 3 | 27
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
edema 3 | 59
female infertility 3 | 60
hydrometra 3 | 53
impaired righting response 3 | 26
increased bone mineral content 3 | 108
increased circulating HDL chol... 3 | 80
increased circulating potassiu... 3 | 29
increased startle reflex 3 | 112
limb grasping 3 | 41
small superior vagus ganglion 3 | 74
tremors 3 | 39
abnormal bone mineralization 2 | 38
abnormal coat- hair morphology 2 | 19
abnormal coat-hair pigmentatio... 2 | 64
abnormal epididymis morphology 2 | 42
abnormal femur morphology 2 | 14
abnormal pericardium morpholog... 2 | 26
abnormal retinal blood vessel ... 2 | 26
abnormal spleen morphology 2 | 55
decreased circulating alanine ... 2 | 47
decreased circulating bilirubi... 2 | 19
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating free fat... 2 | 31
decreased circulating glucose ... 2 | 126
decreased circulating insulin ... 2 | 76
decreased circulating phosphat... 2 | 27
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 31
decreased neutrophil cell numb... 2 | 42
decreased spleen weight 2 | 10
enlarged lymph nodes 2 | 37
enlarged uterus 2 | 11
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased circulating creatini... 2 | 38
increased circulating sodium l... 2 | 71
increased circulating total pr... 2 | 28
increased eosinophil cell numb... 2 | 11
increased erythrocyte cell num... 2 | 39
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 47
increased or absent threshold ... 2 | 101
microphthalmia 2 | 26
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
small seminal vesicle 2 | 10
small testis 2 | 58

Disease

Cancer 338 | 2,499
Carcinoma 259 | 11,493
ovarian cancer 236 | 8,520
glioblastoma 217 | 5,792
lung cancer 211 | 4,740
psoriasis 206 | 6,694
osteosarcoma 190 | 7,950
malignant mesothelioma 161 | 3,232
lung carcinoma 160 | 2,843
invasive ductal carcinoma 156 | 2,951
medulloblastoma, large-cell 154 | 6,241
Breast cancer 149 | 3,578
atypical teratoid / rhabdoid tumor 147 | 5,112
ependymoma 147 | 4,679
non-small cell lung cancer 147 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 144 | 3,291
Astrocytoma, Pilocytic 141 | 3,081
lung adenocarcinoma 141 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 136 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 133 | 2,955
adult high grade glioma 130 | 3,801
pancreatic cancer 128 | 2,398
diabetes mellitus 126 | 1,728
Vascular disease 122 | 319
interstitial cystitis 121 | 2,312
ulcerative colitis 114 | 1,819
tuberculosis 110 | 2,010
cystic fibrosis 102 | 1,696
group 3 medulloblastoma 97 | 4,104
breast carcinoma 95 | 1,638
ductal carcinoma in situ 94 | 1,745
Kidney disease 91 | 430
oligodendroglioma 90 | 2,850
Schizophrenia 86 | 1,160
pituitary cancer 83 | 1,972
primitive neuroectodermal tumor 83 | 3,035
subependymal giant cell astrocytoma 80 | 2,287
Hypertension 74 | 396
Kidney cancer 74 | 2,613
colon cancer 74 | 1,478
Arthritis 73 | 290
Breast Neoplasms 73 | 445
Liver Cirrhosis, Experimental 73 | 769
Mammary Neoplasms 72 | 425
Rheumatoid arthritis 70 | 1,191
cutaneous lupus erythematosus 70 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 70 | 1,962
Multiple Sclerosis 67 | 540
Atherosclerosis 66 | 291
Hypersensitivity reaction type II disease 66 | 253
group 4 medulloblastoma 66 | 1,855
adrenocortical carcinoma 65 | 1,428
Asthma 64 | 385
astrocytic glioma 62 | 2,597
juvenile dermatomyositis 61 | 1,187
Obesity 59 | 678
Anemia 58 | 365
primary pancreatic ductal adenocarcinoma 57 | 1,109
gastric carcinoma 56 | 807
Lung disease 55 | 142
Autosomal recessive predisposition 54 | 1,442
Coronary artery disease 54 | 268
astrocytoma 53 | 1,146
dermatomyositis 53 | 966
Liver disease 52 | 237
Inflammatory bowel disease 51 | 151
nasopharyngeal carcinoma 51 | 1,058
Cerebrovascular disease 48 | 238
Prostatic Neoplasms 48 | 495
acute quadriplegic myopathy 48 | 1,158
Alzheimer's disease 46 | 658
Duchenne muscular dystrophy 46 | 601
Thrombocytopenia 46 | 197
mucosa-associated lymphoid tissue lymphoma 45 | 484
Heart disease 44 | 306
Neoplasm Metastasis 44 | 168
Pick disease 44 | 1,894
Melanoma 43 | 711
Stomach Neoplasms 43 | 300
Liver carcinoma 42 | 240
esophageal adenocarcinoma 42 | 737
Atopic dermatitis 41 | 952
Carcinoma, Hepatocellular 41 | 228
Lung Neoplasms 41 | 232
Bipolar Disorder 40 | 666
Dermatitis 40 | 157
Hypertensive disease 40 | 292
Neoplasm Invasiveness 40 | 161
autosomal dominant Emery-Dreifuss muscular dystrophy 39 | 510
pediatric high grade glioma 39 | 1,064
Depressive disorder 38 | 409
Down syndrome 38 | 499
Malaria 38 | 160
Pneumonia 38 | 174
Multiple myeloma 37 | 1,332
active ulcerative colitis 37 | 764
fibroadenoma 37 | 559
Endometriosis 36 | 540
Myocardial Ischemia 36 | 169
primary Sjogren syndrome 35 | 735

Tissue

Digestive Tract 385 | 17,369
Female tissues 385 | 17,400
Endocrine System 384 | 18,159
Blood and immune system 383 | 16,909
Male tissues 383 | 17,142
Liver and Pancreas 382 | 16,750
Skin and soft tissues 381 | 17,230
Urinary Tract 378 | 16,678
Respiratory system 377 | 16,393
Nervous System 369 | 16,725
Cardiovascular System 351 | 15,192

Target Family

Non-IDG 231 | 12,091
Enzyme 72 | 4,145
Kinase 41 | 634
Transcription Factor 29 | 1,400
GPCR 17 | 408
Nuclear Receptor 4 | 48
Transporter 3 | 473
Epigenetic 1 | 242

Jensen-TM Tissue

Blood vessel 398 | 398
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Gap junction beta-6 protein GJB6 Tbio Non-IDG -2.99235 908.9 170
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297
Mitogen-activated protein kinase 7 MAPK7 Tbio Kinase -2.48754 340.0 422
Platelet-derived growth factor C PDGFC Tbio Non-IDG -2.03910 120.6 226
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610