Development Level

Tbio 98 | 11,445
Tchem 46 | 1,598
Tclin 16 | 613
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased bone mineral content 3 | 151
increased total body fat amoun... 3 | 134
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral density 2 | 126
decreased circulating insulin ... 2 | 76
decreased fasted circulating g... 2 | 65
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased neutrophil cell numb... 2 | 42
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased red blood cell distr... 2 | 34
prenatal lethality prior to he... 2 | 87
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
small testis 2 | 58
abnormal behavior 1 | 298
abnormal coat- hair morphology 1 | 19
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
absent optic nerve 1 | 2
cataract 1 | 92
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased large unstained cell... 1 | 11
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased circulating unsatura... 1 | 1
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased startle reflex 1 | 112
limb grasping 1 | 41
male infertility 1 | 123
prolonged RR interval 1 | 8
scaly skin 1 | 4
thick skin 1 | 4
tremors 1 | 39

Disease

Carcinoma 103 | 11,493
diabetes mellitus 69 | 1,728
psoriasis 60 | 6,694
ovarian cancer 56 | 8,520
Obesity 53 | 678
osteosarcoma 53 | 7,950
Cancer 51 | 2,499
pancreatic ductal adenocarcinoma liver metastasis 50 | 1,962
lung cancer 45 | 4,740
Atherosclerosis 44 | 291
Autosomal recessive predisposition 44 | 1,442
Coronary artery disease 43 | 268
glioblastoma 43 | 5,792
medulloblastoma, large-cell 42 | 6,241
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
invasive ductal carcinoma 39 | 2,951
lung carcinoma 36 | 2,843
Lipid metabolism disorder 35 | 114
ependymoma 35 | 4,679
atypical teratoid / rhabdoid tumor 34 | 5,112
Hypertension 32 | 396
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
Kidney disease 31 | 430
adult high grade glioma 31 | 3,801
non-small cell lung cancer 31 | 2,890
Astrocytoma, Pilocytic 30 | 3,081
lung adenocarcinoma 29 | 2,716
ductal carcinoma in situ 28 | 1,745
malignant mesothelioma 28 | 3,232
Cerebrovascular disease 26 | 238
Liver disease 25 | 237
Breast cancer 24 | 3,578
Vascular disease 24 | 319
Schizophrenia 23 | 1,160
astrocytic glioma 23 | 2,597
oligodendroglioma 23 | 2,850
group 3 medulloblastoma 22 | 4,104
cystic fibrosis 21 | 1,696
pituitary cancer 21 | 1,972
primitive neuroectodermal tumor 21 | 3,035
Fatty liver disease 20 | 103
breast carcinoma 20 | 1,638
pancreatic cancer 20 | 2,398
tuberculosis 20 | 2,010
Hyperglycemia 19 | 137
adrenocortical carcinoma 19 | 1,428
Liver Cirrhosis, Experimental 18 | 769
interstitial cystitis 18 | 2,312
Diarrhea 17 | 253
Hypertensive disease 17 | 292
Kidney cancer 17 | 2,613
Rheumatoid arthritis 17 | 1,191
Thrombophilia 17 | 38
ulcerative colitis 17 | 1,819
Cardiovascular system disease 16 | 246
Hypoglycemia 16 | 152
Polycystic ovary syndrome 16 | 360
Atopic dermatitis 15 | 952
Chemical and Drug Induced Liver Injury 15 | 195
Cholestasis 15 | 155
Disseminated intravascular coagulation 15 | 38
Pancreatitis 15 | 123
Epilepsy 14 | 792
Heart disease 14 | 306
active ulcerative colitis 14 | 764
colon cancer 14 | 1,478
fibroadenoma 14 | 559
subependymal giant cell astrocytoma 14 | 2,287
Alzheimer's disease 13 | 658
Depressive disorder 13 | 409
Liver Cirrhosis 13 | 181
Venous Thrombosis 13 | 47
gastric carcinoma 13 | 807
group 4 medulloblastoma 13 | 1,855
nephrosclerosis 13 | 333
Prostatic Neoplasms 12 | 495
Pulmonary embolism 12 | 55
Seizures 12 | 596
Alcoholic Intoxication, Chronic 11 | 289
Anemia 11 | 365
Bipolar Disorder 11 | 666
Constipation 11 | 181
Cushing's syndrome 11 | 48
Duchenne muscular dystrophy 11 | 601
Heart failure 11 | 162
Hypercholesterolemia 11 | 44
Hypercholesterolemia, Familial 11 | 23
Lung Neoplasms 11 | 232
Melanoma 11 | 711
Mental Depression 11 | 333
Thrombosis 11 | 46
acute quadriplegic myopathy 11 | 1,158
cutaneous lupus erythematosus 11 | 1,057
Adenoma 10 | 167
Hyperinsulinism 10 | 133
Hypertriglyceridemia 10 | 17
Major Depressive Disorder 10 | 301
Thrombocytopenia 10 | 197
Pick disease 9 | 1,894

Tissue

Endocrine System 157 | 18,159
Digestive Tract 156 | 17,369
Liver and Pancreas 151 | 16,750
Female tissues 149 | 17,400
Skin and soft tissues 145 | 17,230
Male tissues 142 | 17,142
Urinary Tract 142 | 16,678
Blood and immune system 135 | 16,909
Nervous System 132 | 16,725
Respiratory system 127 | 16,393
Cardiovascular System 104 | 15,192

Target Family

Non-IDG 89 | 12,091
Enzyme 53 | 4,145
Transporter 9 | 473
Transcription Factor 5 | 1,400
GPCR 4 | 408
Kinase 2 | 634
Epigenetic 1 | 242

Jensen-TM Tissue

Blood plasma 163 | 163
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adrenocorticotropic hormone receptor MC2R Tclin GPCR -2.22640 172.4 223
Lipase maturation factor 1 LMF1 Tbio Enzyme -1.30021 24.5 35
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1 Tchem Enzyme -2.62147 370.7 267
UDP-glucuronosyltransferase 2B7 UGT2B7 Tchem Enzyme -2.31570 219.0 131
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 DDAH1 Tchem Enzyme -2.13636 144.4 205
Mitochondrial uncoupling protein 3 UCP3 Tbio Non-IDG -2.74050 585.4 181
Peptidyl-prolyl cis-trans isomerase G PPIG Tchem Enzyme -3.69407 4421.0 219
Conserved oligomeric Golgi complex subunit 1 COG1 Tbio Non-IDG -1.68066 45.6 91
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139
Coagulation factor V F5 Tbio Non-IDG -2.73955 525.3 198