Development Level

Tbio 1,275 | 11,651
Tchem 419 | 1,388
Tclin 246 | 612
Tdark 22 | 6,593

Collection

GPCR: IDG Consortium (Complete... 4 | 25

IMPC Phenotype

preweaning lethality, complete... 115 | 979
preweaning lethality, incomple... 62 | 499
enlarged heart 41 | 210
decreased vertical activity 40 | 208
embryonic lethality prior to t... 38 | 278
abnormal behavior 33 | 298
abnormal heart morphology 30 | 162
embryonic lethality prior to o... 30 | 239
abnormal embryo size 28 | 220
decreased total body fat amoun... 28 | 207
increased lean body mass 25 | 172
abnormal bone structure 24 | 187
abnormal seminal vesicle morph... 22 | 114
hypoactivity 21 | 132
increased total body fat amoun... 21 | 134
decreased body weight 19 | 161
decreased mean corpuscular vol... 18 | 79
increased circulating alkaline... 18 | 122
increased startle reflex 18 | 112
abnormal retina morphology 17 | 71
decreased bone mineral content 17 | 151
decreased lymphocyte cell numb... 17 | 83
decreased bone mineral density 15 | 126
decreased circulating triglyce... 15 | 79
short tibia 15 | 97
abnormal lens morphology 14 | 81
decreased circulating choleste... 14 | 93
decreased erythrocyte cell num... 14 | 62
embryonic growth retardation 14 | 106
hyperactivity 14 | 148
improved glucose tolerance 14 | 79
increased bone mineral content 14 | 108
increased circulating HDL chol... 14 | 80
increased neutrophil cell numb... 14 | 46
small superior vagus ganglion 14 | 74
thrombocytopenia 14 | 56
cataract 13 | 92
decreased circulating glucose ... 13 | 126
decreased grip strength 13 | 116
increased circulating choleste... 13 | 66
increased mean corpuscular hem... 13 | 96
male infertility 13 | 123
decreased hemoglobin content 12 | 68
decreased prepulse inhibition 12 | 82
increased mean corpuscular vol... 12 | 92
decreased circulating HDL chol... 11 | 68
decreased lean body mass 11 | 135
impaired glucose tolerance 11 | 75
increased monocyte cell number 11 | 63
abnormal skin morphology 10 | 50
abnormal sleep behavior 10 | 70
decreased body length 10 | 101
decreased circulating insulin ... 10 | 76
decreased leukocyte cell numbe... 10 | 73
increased heart weight 10 | 62
prolonged QT interval 10 | 38
prolonged ST segment 10 | 36
decreased circulating serum al... 9 | 82
decreased hematocrit 9 | 46
decreased startle reflex 9 | 75
increased blood urea nitrogen ... 9 | 48
increased circulating sodium l... 9 | 71
abnormal bone mineralization 8 | 38
abnormal gait 8 | 69
decreased circulating alanine ... 8 | 47
decreased circulating alkaline... 8 | 46
decreased heart weight 8 | 27
decreased mean corpuscular hem... 8 | 50
edema 8 | 59
enlarged lymph nodes 8 | 37
enlarged spleen 8 | 41
impaired righting response 8 | 26
increased fasted circulating g... 8 | 76
increased hemoglobin content 8 | 45
increased or absent threshold ... 8 | 101
abnormal eye morphology 7 | 68
cardiovascular system phenotyp... 7 | 36
decreased circulating amylase ... 7 | 28
decreased circulating creatini... 7 | 39
female infertility 7 | 60
hydrometra 7 | 53
increased bone mineral density 7 | 72
increased circulating calcium ... 7 | 34
increased grip strength 7 | 41
limb grasping 7 | 41
prenatal lethality prior to he... 7 | 87
abnormal behavioral response t... 6 | 66
abnormal lung morphology 6 | 26
abnormal retinal vasculature m... 6 | 27
abnormal testis morphology 6 | 43
decreased blood urea nitrogen ... 6 | 51
decreased fasted circulating g... 6 | 65
decreased lactate dehydrogenas... 6 | 16
decreased mean corpuscular hem... 6 | 31
decreased neutrophil cell numb... 6 | 42
increased circulating potassiu... 6 | 29
increased circulating triglyce... 6 | 42
microphthalmia 6 | 26
small testis 6 | 58
thin ventricular wall 6 | 24

Disease

Carcinoma 1,266 | 11,493
Cancer 1,192 | 2,499
psoriasis 1,014 | 6,694
ovarian cancer 1,010 | 8,520
osteosarcoma 918 | 7,950
lung cancer 850 | 4,740
glioblastoma 797 | 5,792
medulloblastoma, large-cell 667 | 6,241
lung carcinoma 551 | 2,843
diabetes mellitus 547 | 1,728
malignant mesothelioma 546 | 3,232
atypical teratoid / rhabdoid tumor 533 | 5,112
ependymoma 525 | 4,679
Breast cancer 514 | 3,578
non-small cell lung cancer 505 | 2,890
invasive ductal carcinoma 491 | 2,951
lung adenocarcinoma 484 | 2,716
adult high grade glioma 472 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 472 | 3,291
pancreatic cancer 469 | 2,398
interstitial cystitis 457 | 2,312
Astrocytoma, Pilocytic 456 | 3,081
tuberculosis 449 | 2,010
intraductal papillary-mucinous carcinoma (IPMC) 446 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 438 | 2,955
group 3 medulloblastoma 426 | 4,104
ulcerative colitis 408 | 1,819
subependymal giant cell astrocytoma 349 | 2,287
Autosomal recessive predisposition 346 | 1,442
cystic fibrosis 340 | 1,696
Schizophrenia 330 | 1,160
Rheumatoid arthritis 328 | 1,191
Kidney cancer 319 | 2,613
oligodendroglioma 318 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 308 | 1,962
cutaneous lupus erythematosus 304 | 1,057
breast carcinoma 301 | 1,638
primitive neuroectodermal tumor 300 | 3,035
pituitary cancer 288 | 1,972
ductal carcinoma in situ 284 | 1,745
Hypertension 277 | 396
Kidney disease 275 | 430
colon cancer 270 | 1,478
astrocytic glioma 261 | 2,597
Liver Cirrhosis, Experimental 250 | 769
Obesity 250 | 678
Arthritis 247 | 290
adrenocortical carcinoma 241 | 1,428
juvenile dermatomyositis 230 | 1,187
dermatomyositis 220 | 966
Asthma 218 | 385
Anemia 217 | 365
Multiple myeloma 213 | 1,332
Multiple Sclerosis 212 | 540
astrocytoma 211 | 1,146
group 4 medulloblastoma 211 | 1,855
primary pancreatic ductal adenocarcinoma 207 | 1,109
Breast Neoplasms 203 | 445
Hypersensitivity reaction type II disease 203 | 253
Mammary Neoplasms 199 | 425
Vascular disease 197 | 319
Atopic dermatitis 194 | 952
acute quadriplegic myopathy 192 | 1,158
Bipolar Disorder 190 | 666
Atherosclerosis 185 | 291
Prostatic Neoplasms 185 | 495
Alzheimer's disease 184 | 658
Epilepsy 181 | 792
Pick disease 179 | 1,894
primary Sjogren syndrome 179 | 735
Intellectual disability 178 | 1,016
nasopharyngeal carcinoma 175 | 1,058
Depressive disorder 174 | 409
esophageal adenocarcinoma 172 | 737
Liver disease 165 | 237
gastric carcinoma 163 | 807
Hypertensive disease 162 | 292
Seizures 162 | 596
Coronary artery disease 161 | 268
Cerebrovascular disease 157 | 238
active Crohn's disease 157 | 922
Heart disease 156 | 306
pediatric high grade glioma 148 | 1,064
Short stature 147 | 531
Melanoma 144 | 711
Duchenne muscular dystrophy 143 | 601
Dull intelligence 141 | 645
Low intelligence 141 | 645
Mental Retardation 141 | 645
Mental deficiency 141 | 645
Poor school performance 141 | 645
active ulcerative colitis 139 | 764
Waldenstrons macroglobulinemia 138 | 765
mucosa-associated lymphoid tissue lymphoma 137 | 484
Endometriosis 134 | 540
Osteoporosis 132 | 363
Diarrhea 131 | 253
Stomach Neoplasms 126 | 300
Inflammatory bowel disease 125 | 151
Liver carcinoma 125 | 240

Tissue

Endocrine System 1,830 | 18,159
Digestive Tract 1,822 | 17,369
Skin and soft tissues 1,807 | 17,230
Female tissues 1,806 | 17,400
Blood and immune system 1,795 | 16,909
Liver and Pancreas 1,793 | 16,750
Male tissues 1,782 | 17,142
Urinary Tract 1,781 | 16,678
Respiratory system 1,757 | 16,393
Nervous System 1,736 | 16,725
Cardiovascular System 1,620 | 15,192

Target Family

Non-IDG 1,043 | 12,091
Enzyme 475 | 4,145
Kinase 121 | 634
Transcription Factor 118 | 1,400
GPCR 81 | 408
Transporter 54 | 473
Epigenetic 25 | 242
Ion Channel 23 | 344
Nuclear Receptor 18 | 48
TF/Epigenetic 4 | 38

Jensen-TM Tissue

Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Paraneoplastic antigen Ma2 PNMA2 Tbio Non-IDG -2.92781 822.4 113
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
ATP-binding cassette sub-family A member 1 ABCA1 Tclin Transporter -3.15111 1451.8 388
Phosducin PDC Tbio Non-IDG -2.36871 242.5 78
Filaggrin FLG Tbio Non-IDG -3.03594 1055.2 253
Neuroendocrine secretory protein 55 GNAS Tbio Non-IDG -2.63356 1389.7 509