Development Level

Tbio 1,174 | 11,178
Tchem 521 | 1,885
Tclin 246 | 612
Tdark 21 | 6,569

Collection

GPCR: IDG Consortium (Complete... 4 | 25

IMPC Phenotype

preweaning lethality, complete... 115 | 979
preweaning lethality, incomple... 62 | 499
enlarged heart 41 | 210
decreased vertical activity 40 | 208
embryonic lethality prior to t... 38 | 278
abnormal behavior 33 | 298
abnormal heart morphology 30 | 162
embryonic lethality prior to o... 30 | 239
abnormal embryo size 28 | 220
decreased total body fat amoun... 28 | 207
increased lean body mass 25 | 172
abnormal bone structure 24 | 187
abnormal seminal vesicle morph... 22 | 114
hypoactivity 21 | 132
increased total body fat amoun... 21 | 134
decreased body weight 19 | 161
decreased mean corpuscular vol... 18 | 79
increased circulating alkaline... 18 | 122
increased startle reflex 18 | 112
abnormal retina morphology 17 | 71
decreased bone mineral content 17 | 151
decreased lymphocyte cell numb... 17 | 83
decreased bone mineral density 15 | 126
decreased circulating triglyce... 15 | 79
short tibia 15 | 97
abnormal lens morphology 14 | 81
decreased circulating choleste... 14 | 93
decreased erythrocyte cell num... 14 | 62
embryonic growth retardation 14 | 106
hyperactivity 14 | 148
improved glucose tolerance 14 | 79
increased bone mineral content 14 | 108
increased circulating HDL chol... 14 | 80
increased neutrophil cell numb... 14 | 46
small superior vagus ganglion 14 | 74
thrombocytopenia 14 | 56
cataract 13 | 92
decreased circulating glucose ... 13 | 126
decreased grip strength 13 | 116
increased circulating choleste... 13 | 66
increased mean corpuscular hem... 13 | 96
male infertility 13 | 123
decreased hemoglobin content 12 | 68
decreased prepulse inhibition 12 | 82
increased mean corpuscular vol... 12 | 92
decreased circulating HDL chol... 11 | 68
decreased lean body mass 11 | 135
impaired glucose tolerance 11 | 75
increased monocyte cell number 11 | 63
abnormal skin morphology 10 | 50
abnormal sleep behavior 10 | 70
decreased body length 10 | 101
decreased circulating insulin ... 10 | 76
decreased leukocyte cell numbe... 10 | 73
increased heart weight 10 | 62
prolonged QT interval 10 | 38
prolonged ST segment 10 | 36
decreased circulating serum al... 9 | 82
decreased hematocrit 9 | 46
decreased startle reflex 9 | 75
increased blood urea nitrogen ... 9 | 48
increased circulating sodium l... 9 | 71
abnormal bone mineralization 8 | 38
abnormal gait 8 | 69
decreased circulating alanine ... 8 | 47
decreased circulating alkaline... 8 | 46
decreased heart weight 8 | 27
decreased mean corpuscular hem... 8 | 50
edema 8 | 59
enlarged lymph nodes 8 | 37
enlarged spleen 8 | 41
impaired righting response 8 | 26
increased fasted circulating g... 8 | 76
increased hemoglobin content 8 | 45
increased or absent threshold ... 8 | 101
abnormal eye morphology 7 | 68
cardiovascular system phenotyp... 7 | 36
decreased circulating amylase ... 7 | 28
decreased circulating creatini... 7 | 39
female infertility 7 | 60
hydrometra 7 | 53
increased bone mineral density 7 | 72
increased circulating calcium ... 7 | 34
increased grip strength 7 | 41
limb grasping 7 | 41
prenatal lethality prior to he... 7 | 87
abnormal behavioral response t... 6 | 66
abnormal lung morphology 6 | 26
abnormal retinal vasculature m... 6 | 27
abnormal testis morphology 6 | 43
decreased blood urea nitrogen ... 6 | 51
decreased fasted circulating g... 6 | 65
decreased lactate dehydrogenas... 6 | 16
decreased mean corpuscular hem... 6 | 31
decreased neutrophil cell numb... 6 | 42
increased circulating potassiu... 6 | 29
increased circulating triglyce... 6 | 42
microphthalmia 6 | 26
small testis 6 | 58
thin ventricular wall 6 | 24

Disease

Carcinoma 1,218 | 11,192
Cancer 1,146 | 2,388
psoriasis 979 | 6,514
ovarian cancer 972 | 8,297
osteosarcoma 889 | 7,766
lung cancer 817 | 4,607
glioblastoma 766 | 5,635
medulloblastoma, large-cell 647 | 6,086
lung carcinoma 530 | 2,755
diabetes mellitus 529 | 1,683
malignant mesothelioma 523 | 3,135
atypical teratoid / rhabdoid tumor 513 | 4,971
ependymoma 501 | 4,559
Breast cancer 487 | 3,469
non-small cell lung cancer 481 | 2,799
invasive ductal carcinoma 469 | 2,867
lung adenocarcinoma 462 | 2,627
adult high grade glioma 457 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 456 | 3,204
pancreatic cancer 444 | 2,322
interstitial cystitis 442 | 2,237
Astrocytoma, Pilocytic 440 | 3,006
tuberculosis 438 | 1,963
intraductal papillary-mucinous carcinoma (IPMC) 427 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 420 | 2,872
group 3 medulloblastoma 412 | 4,002
ulcerative colitis 390 | 1,765
subependymal giant cell astrocytoma 335 | 2,230
Autosomal recessive predisposition 332 | 1,407
Schizophrenia 320 | 1,136
Rheumatoid arthritis 319 | 1,156
cystic fibrosis 317 | 1,629
oligodendroglioma 307 | 2,768
Kidney cancer 305 | 2,548
pancreatic ductal adenocarcinoma liver metastasis 298 | 1,911
cutaneous lupus erythematosus 292 | 1,016
primitive neuroectodermal tumor 289 | 2,957
breast carcinoma 286 | 1,589
pituitary cancer 278 | 1,915
ductal carcinoma in situ 265 | 1,686
Kidney disease 260 | 411
Hypertension 258 | 372
colon cancer 257 | 1,428
astrocytic glioma 252 | 2,530
Obesity 237 | 655
Arthritis 233 | 276
adrenocortical carcinoma 232 | 1,385
Liver Cirrhosis, Experimental 225 | 733
juvenile dermatomyositis 221 | 1,147
dermatomyositis 212 | 941
Asthma 209 | 370
Anemia 208 | 353
Multiple Sclerosis 207 | 527
Multiple myeloma 206 | 1,296
group 4 medulloblastoma 201 | 1,806
astrocytoma 200 | 1,113
Hypersensitivity reaction type II disease 199 | 245
primary pancreatic ductal adenocarcinoma 196 | 1,071
Breast Neoplasms 193 | 423
Mammary Neoplasms 189 | 403
acute quadriplegic myopathy 187 | 1,133
Vascular disease 185 | 294
Atopic dermatitis 184 | 915
Bipolar Disorder 182 | 646
Alzheimer's disease 176 | 640
Epilepsy 176 | 775
Atherosclerosis 175 | 276
Intellectual disability 174 | 998
Pick disease 174 | 1,856
Prostatic Neoplasms 174 | 472
primary Sjogren syndrome 170 | 710
Depressive disorder 167 | 401
nasopharyngeal carcinoma 167 | 1,024
Seizures 159 | 584
esophageal adenocarcinoma 158 | 696
Liver disease 157 | 227
gastric carcinoma 154 | 781
Hypertensive disease 152 | 278
Coronary artery disease 151 | 253
active Crohn's disease 148 | 882
Cerebrovascular disease 147 | 223
Heart disease 146 | 288
Melanoma 141 | 689
pediatric high grade glioma 140 | 1,035
Short stature 139 | 514
Dull intelligence 137 | 634
Low intelligence 137 | 634
Mental Retardation 137 | 634
Mental deficiency 137 | 634
Poor school performance 137 | 634
Duchenne muscular dystrophy 135 | 587
Waldenstrons macroglobulinemia 134 | 742
mucosa-associated lymphoid tissue lymphoma 132 | 473
active ulcerative colitis 131 | 736
Diarrhea 129 | 245
Endometriosis 124 | 521
Osteoporosis 123 | 348
Inflammatory bowel disease 122 | 148
Stomach Neoplasms 120 | 287
spina bifida 120 | 1,053

Tissue

Endocrine System 1,830 | 18,159
Digestive Tract 1,822 | 17,369
Skin and soft tissues 1,807 | 17,230
Female tissues 1,806 | 17,400
Blood and immune system 1,795 | 16,909
Liver and Pancreas 1,793 | 16,750
Male tissues 1,782 | 17,142
Urinary Tract 1,781 | 16,678
Respiratory system 1,757 | 16,393
Nervous System 1,736 | 16,725
Cardiovascular System 1,620 | 15,192

Target Family

Non-IDG 1,043 | 12,091
Enzyme 475 | 4,145
Kinase 121 | 634
Transcription Factor 118 | 1,400
GPCR 81 | 408
Transporter 54 | 473
Epigenetic 25 | 242
Ion Channel 23 | 344
Nuclear Receptor 18 | 48
TF/Epigenetic 4 | 38

Jensen-TM Tissue

Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 2-A HIST2H2AA3 Tbio Non-IDG -3.04065 999.3 88
Potassium voltage-gated channel subfamily H member 1 KCNH1 Tclin Ion Channel -2.86111 714.2 150
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
Histone H2A type 2-C HIST2H2AC Tbio Non-IDG -3.03938 994.7 101
Histone H2B type 2-E HIST2H2BE Tbio Non-IDG -3.48425 2920.0 135
Cannabinoid receptor 2 CNR2 Tchem GPCR -2.45761 269.7 345
MyoD family inhibitor domain-containing protein MDFIC Tbio Non-IDG -2.90969 749.0 122
T-lymphocyte activation antigen CD80 CD80 Tclin Non-IDG -3.39216 2405.6 1323
Cathepsin D CTSD Tchem Enzyme -3.47061 2866.8 779
HLA class I histocompatibility antigen, B-67 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 362