Development Level

Tbio 1,115 | 10,625
Tchem 500 | 1,890
Tclin 225 | 602
Tdark 27 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 78 | 633
preweaning lethality, incomple... 33 | 260
embryonic lethality prior to t... 28 | 187
abnormal behavior 26 | 226
decreased lean body mass 23 | 195
decreased total body fat amoun... 23 | 186
decreased bone mineral content 21 | 157
decreased body weight 20 | 174
decreased bone mineral density 20 | 126
enlarged heart 20 | 111
embryonic lethality prior to o... 19 | 148
abnormal bone structure 18 | 131
abnormal retina morphology 18 | 100
increased circulating alkaline... 18 | 119
abnormal embryo size 17 | 112
decreased body length 17 | 108
decreased circulating triglyce... 15 | 83
hypoactivity 14 | 89
abnormal bone mineralization 13 | 55
increased lean body mass 13 | 107
increased mean corpuscular vol... 13 | 91
short tibia 13 | 82
decreased circulating glucose ... 12 | 121
decreased circulating insulin ... 12 | 75
decreased grip strength 12 | 123
increased grip strength 12 | 83
increased mean corpuscular hem... 12 | 93
abnormal lens morphology 11 | 73
decreased circulating alanine ... 11 | 53
decreased hemoglobin content 11 | 53
decreased erythrocyte cell num... 10 | 43
improved glucose tolerance 10 | 56
increased circulating HDL chol... 10 | 63
increased or absent threshold ... 10 | 128
thrombocytopenia 10 | 46
abnormal heart morphology 9 | 51
abnormal sleep behavior 9 | 63
decreased circulating HDL chol... 9 | 77
decreased heart weight 9 | 44
increased circulating choleste... 9 | 53
increased circulating sodium l... 9 | 71
abnormal gait 8 | 51
decreased circulating choleste... 8 | 85
decreased mean corpuscular vol... 8 | 50
decreased prepulse inhibition 8 | 52
increased blood urea nitrogen ... 8 | 44
increased body weight 8 | 42
increased fasted circulating g... 8 | 68
increased total body fat amoun... 8 | 57
male infertility 8 | 62
abnormal neural tube closure 7 | 37
abnormal skin morphology 7 | 23
cataract 7 | 26
decreased circulating alkaline... 7 | 41
decreased hematocrit 7 | 25
decreased leukocyte cell numbe... 7 | 54
hyperactivity 7 | 108
increased bone mineral content 7 | 92
increased circulating potassiu... 7 | 31
increased circulating triglyce... 7 | 24
increased heart weight 7 | 37
increased hemoglobin content 7 | 45
tremors 7 | 34
abnormal QRS complex 6 | 25
abnormal cranium morphology 6 | 32
abnormal epididymis morphology 6 | 31
decreased blood urea nitrogen ... 6 | 31
decreased caudal vertebrae num... 6 | 49
decreased rib number 6 | 59
impaired glucose tolerance 6 | 52
increased hematocrit 6 | 36
limb grasping 6 | 35
abnormal behavioral response t... 5 | 52
abnormal coat/hair pigmentatio... 5 | 54
abnormal coping response 5 | 12
abnormal hindbrain development 5 | 24
abnormal midbrain development 5 | 22
abnormal retinal pigmentation 5 | 61
abnormal seminal vesicle morph... 5 | 47
cardiovascular system phenotyp... 5 | 35
decreased CD4-positive, CD25-p... 5 | 24
decreased NK T cell number 5 | 28
decreased circulating amylase ... 5 | 24
decreased circulating aspartat... 5 | 27
decreased circulating calcium ... 5 | 33
decreased circulating creatini... 5 | 31
decreased circulating free fat... 5 | 39
decreased circulating serum al... 5 | 79
decreased lactate dehydrogenas... 5 | 14
decreased monocyte cell number 5 | 28
enlarged epididymis 5 | 27
enlarged lymph nodes 5 | 27
enlarged spleen 5 | 26
hydrops fetalis 5 | 22
increased bone mineral density 5 | 52
increased circulating calcium ... 5 | 32
increased circulating creatini... 5 | 29
increased exploration in new e... 5 | 56
increased leukocyte cell numbe... 5 | 37
small superior vagus ganglion 5 | 20

Disease

Cancer 1,122 | 2,346
psoriasis 969 | 6,685
ovarian cancer 951 | 8,484
osteosarcoma 868 | 7,933
lung cancer 769 | 4,466
glioblastoma 730 | 5,572
medulloblastoma, large-cell 635 | 6,234
lung carcinoma 525 | 2,844
diabetes mellitus 492 | 1,663
malignant mesothelioma 487 | 3,162
invasive ductal carcinoma 470 | 2,950
non-small cell lung cancer 470 | 2,798
lung adenocarcinoma 458 | 2,713
intraductal papillary-mucinous neoplasm (IPMN) 453 | 3,289
ulcerative colitis 450 | 2,087
pilocytic astrocytoma 439 | 3,086
pancreatic cancer 436 | 2,300
interstitial cystitis 435 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 430 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 422 | 2,956
atypical teratoid / rhabdoid tumor 419 | 4,369
Breast cancer 401 | 3,094
tuberculosis 366 | 1,557
pediatric high grade glioma 351 | 2,712
subependymal giant cell astrocytoma 335 | 2,287
Rheumatoid Arthritis 321 | 1,160
cystic fibrosis 317 | 1,665
oligodendroglioma 297 | 2,849
cutaneous lupus erythematosus 291 | 1,056
primitive neuroectodermal tumor 282 | 3,031
Carcinoma 277 | 2,147
ductal carcinoma in situ 275 | 1,745
breast carcinoma 274 | 1,614
pituitary cancer 271 | 1,972
Kidney disease 259 | 396
colon cancer 257 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 254 | 1,795
astrocytoma 250 | 1,493
adult high grade glioma 246 | 2,148
posterior fossa group A ependymoma 246 | 1,511
ependymoma 243 | 2,514
adrenocortical carcinoma 234 | 1,427
primary pancreatic ductal adenocarcinoma 232 | 1,271
group 3 medulloblastoma 224 | 2,254
Obesity 223 | 616
juvenile dermatomyositis 223 | 1,189
Arthritis 220 | 248
group 4 medulloblastoma 208 | 1,875
Hypertension 205 | 287
Asthma 204 | 349
Multiple myeloma 201 | 1,327
Multiple Sclerosis 200 | 498
Mammary Neoplasms 194 | 410
astrocytic glioma 194 | 2,241
Hypersensitivity reaction type II disease 192 | 235
acute quadriplegic myopathy 191 | 1,157
primary Sjogren syndrome 190 | 789
Atopic dermatitis 185 | 944
dermatomyositis 182 | 933
Vascular disease 177 | 281
Prostatic Neoplasms 175 | 471
gastric carcinoma 175 | 832
Alzheimer's disease 172 | 644
Anemia 171 | 252
Atherosclerosis 171 | 275
nasopharyngeal carcinoma 169 | 1,056
Pick disease 165 | 1,893
esophageal adenocarcinoma 162 | 737
sonic hedgehog group medulloblastoma 153 | 1,482
Liver disease 151 | 219
active Crohn's disease 147 | 918
Cerebrovascular disease 143 | 231
medulloblastoma 142 | 1,524
Coronary artery disease 139 | 240
Heart disease 139 | 279
Duchenne muscular dystrophy 137 | 602
mucosa-associated lymphoid tissue lymphoma 134 | 480
Waldenstrons macroglobulinemia 133 | 765
Endometriosis 127 | 535
Down syndrome 124 | 548
atypical teratoid/rhabdoid tumor 123 | 1,095
posterior fossa group B ependymoma 118 | 1,530
Stomach Neoplasms 117 | 282
Inflammatory bowel disease 116 | 142
Schizophrenia 114 | 501
Lung disease 113 | 132
non-small cell lung carcinoma 113 | 413
Acquired immunodeficiency syndrome 112 | 164
acute myeloid leukemia 108 | 780
Ankylosing spondylitis 107 | 138
IGA Glomerulonephritis 107 | 454
Liver carcinoma 107 | 217
Peripheral Neuropathy 106 | 303
sarcoidosis 106 | 358
spina bifida 106 | 1,064
Hypertensive disease 105 | 193
hepatocellular carcinoma 101 | 532
non primary Sjogren syndrome sicca 101 | 840
Lung Neoplasms 100 | 171
pancreatic carcinoma 100 | 567

Tissue

Female tissues 1,772 | 18,647
Digestive Tract 1,771 | 18,473
Nervous System 1,769 | 18,561
Endocrine System 1,764 | 18,512
Urinary Tract 1,762 | 18,444
Liver and Pancreas 1,756 | 18,136
Blood and immune system 1,754 | 17,995
Cardiovascular System 1,743 | 17,958
Skin and soft tissues 1,736 | 18,115
Male tissues 1,735 | 17,969
Respiratory system 1,728 | 17,484

Target Family

Non-IDG 997 | 11,971
Enzyme 450 | 4,146
Transcription Factor 115 | 1,400
Kinase 111 | 634
GPCR 81 | 406
Transporter 51 | 473
Epigenetic 23 | 242
Ion Channel 19 | 341
Nuclear Receptor 16 | 48
TF/Epigenetic 4 | 38

Jensen-TM Tissue

Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.31593 2169.0 108
Chitinase-3-like protein 1 CHI3L1 Tbio Enzyme -2.73776 668.3 248
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628