Development Level

Tbio 8 | 11,445

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal tooth morphology 2 | 24
embryonic lethality prior to o... 2 | 239
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal lung morphology 1 | 26
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
anophthalmia 1 | 33
corneal opacity 1 | 32
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased lean body mass 1 | 172
irregularly shaped pupil 1 | 7
microphthalmia 1 | 26
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

group 3 medulloblastoma 5 | 4,104
malignant mesothelioma 5 | 3,232
Carcinoma 4 | 11,493
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Breast cancer 3 | 3,578
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
medulloblastoma, large-cell 3 | 6,241
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Kidney cancer 2 | 2,613
astrocytoma 2 | 1,146
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
lung cancer 2 | 4,740
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 3 months 2 | 179
ulcerative colitis 2 | 1,819
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
Alagille syndrome 1 | 15
Amyotrophic lateral sclerosis 1 | 451
Aniridia 1 | 25
Arsenic Poisoning 1 | 62
Atrophic rhinitis 1 | 8
Axenfeld anomaly (disorder) 1 | 3
Axenfeld-Rieger syndrome 1 | 14
Brittle cornea syndrome 1 | 4
Cadasil 1 | 10
Ciliopathy 1 | 71
Clouding of corneal stroma 1 | 50
Cogan-Reese syndrome 1 | 3
Congenital Heart Defects 1 | 58
Congenital anomaly of face 1 | 56
Congenital deafness 1 | 185
Congenital heart disease 1 | 93
Congenital keratoglobus 1 | 14
Corneal Opacity 1 | 53
Corneal abnormalities 1 | 6
Corneal diameter increased 1 | 13
Corneal disease 1 | 31
Cornela disease 1 | 6
Craniofacial Abnormalities 1 | 151
Deafness 1 | 198
Decreased projection of maxilla 1 | 66
Decreased projection of midface 1 | 105
Deficiency of upper jaw bones 1 | 66
Dental abnormalities 1 | 60
Dermatologic disorders 1 | 93
Distortion of face 1 | 46
Dysmorphic facies 1 | 46
Embryotoxon 1 | 28
Everted lower lip vermilion 1 | 54
Funny looking face 1 | 46
Gaucher disease type 1 1 | 180
Hearing Loss, Partial 1 | 185
Heart Defects, Congenital 1 | 37
Highly variable severity 1 | 157
Hydrophthalmos 1 | 19
Hypodontia 1 | 81
Hypoplasia of iris 1 | 10
Hypoplasia of the maxilla 1 | 66
Hypotrophic maxilla 1 | 66
Hypotrophic midface 1 | 105
Irido-corneo-trabecular dysgenesis (disorder) 1 | 10
Iridogoniodysgenesis syndrome 1 | 9
Isolated somatotropin deficiency 1 | 30
Large intestine cancer 1 | 126
Major Depressive Disorder 1 | 301
Maxillary retrognathia 1 | 66
Midface retrusion 1 | 105
Pancreatic agenesis 1 | 17
Penile hypospadias 1 | 106
Persistent hyperplastic primary vitreous 1 | 20
Peters anomaly 1 | 16
Pigment dispersion syndrome 1 | 11
Pigmentary iris degeneration 1 | 20
Pineoblastoma 1 | 6
Pituitary hypoplasia 1 | 23
Posterior embryotoxon 1 | 28
Protruding lower lip 1 | 54
Retrusion of upper jaw bones 1 | 66
Septooptic dysplasia 1 | 19
Short philtrum 1 | 53
Skin Diseases 1 | 71
Small midface 1 | 105
Stricture of anus 1 | 13
Thin upper lip vermilion 1 | 67
Tooth Abnormalities 1 | 69
Tooth agenesis 1 | 44
Unipolar Depression 1 | 250
Variable expressivity 1 | 157
Visceral heterotaxy 1 | 14
cystic fibrosis and chronic rhinosinusitis 1 | 214
facial deformity 1 | 46
hearing impairment 1 | 199
interstitial lung disease 1 | 298

Tissue

Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Blood and immune system 7 | 16,909
Nervous System 7 | 16,725
Respiratory system 7 | 16,393

Target Family

Non-IDG 5 | 12,091
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

Jensen-TM Tissue

Blastodisc 8 | 8
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serrate RNA effector molecule homolog SRRT Tbio Non-IDG -2.09395 108.5 108
Pre-mRNA-splicing factor RBM22 RBM22 Tbio Non-IDG -0.84549 7.65 130
SEC14-like protein 2 SEC14L2 Tbio Non-IDG -1.94705 87.1 159
Chromodomain-helicase-DNA-binding protein 1 CHD1 Tbio Epigenetic -2.14472 148.3 122
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Pituitary homeobox 2 PITX2 Tbio Transcription Factor -2.67290 480.0 220
Transcription factor RFX3 RFX3 Tbio Transcription Factor -1.09434 10.9 170
Protein FAM3B FAM3B Tbio Non-IDG -1.94984 97.7 201