Development Level

Tbio 127 | 11,445
Tchem 68 | 1,598
Tclin 51 | 613
Tdark 10 | 6,588

Collection

Ion Channel: IDG Consortium (T... 4 | 99
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 14 | 979
abnormal behavior 9 | 298
abnormal bone structure 7 | 187
embryonic lethality prior to t... 7 | 278
preweaning lethality, incomple... 7 | 499
abnormal embryo size 6 | 220
embryonic lethality prior to o... 5 | 239
increased mean corpuscular vol... 5 | 92
abnormal retina morphology 4 | 71
decreased total body fat amoun... 4 | 207
embryonic growth retardation 4 | 106
hyperactivity 4 | 148
impaired glucose tolerance 4 | 75
increased circulating HDL chol... 4 | 80
increased mean corpuscular hem... 4 | 96
decreased body weight 3 | 161
decreased erythrocyte cell num... 3 | 62
decreased mean corpuscular hem... 3 | 50
hypoactivity 3 | 132
increased bone mineral content 3 | 108
increased circulating creatini... 3 | 38
small testis 3 | 58
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal kidney morphology 2 | 65
abnormal seminal vesicle morph... 2 | 114
abnormal urinary bladder morph... 2 | 11
cardiovascular system phenotyp... 2 | 36
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating alkaline... 2 | 46
decreased circulating chloride... 2 | 30
decreased circulating creatini... 2 | 39
decreased circulating iron lev... 2 | 32
decreased heart weight 2 | 27
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 31
decreased mean platelet volume 2 | 25
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
enlarged epididymis 2 | 31
female infertility 2 | 60
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
increased circulating total pr... 2 | 28
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
small kidney 2 | 16
thrombocytopenia 2 | 56
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
absent startle reflex 1 | 24
cystolithiasis 1 | 3
decreased circulating aspartat... 1 | 34
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased lactate dehydrogenas... 1 | 16
decreased vertical activity 1 | 208
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
increased body length 1 | 32
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
limb grasping 1 | 41
male infertility 1 | 123
pallor 1 | 34
prenatal lethality 1 | 28
small spleen 1 | 19
tremors 1 | 39
urinary bladder obstruction 1 | 4

Disease

Carcinoma 201 | 11,493
psoriasis 112 | 6,694
medulloblastoma, large-cell 111 | 6,241
ovarian cancer 111 | 8,520
glioblastoma 96 | 5,792
atypical teratoid / rhabdoid tumor 94 | 5,112
osteosarcoma 91 | 7,950
lung cancer 80 | 4,740
ependymoma 79 | 4,679
adult high grade glioma 75 | 3,801
group 3 medulloblastoma 75 | 4,104
primitive neuroectodermal tumor 69 | 3,035
Cancer 65 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 65 | 3,291
Kidney cancer 63 | 2,613
malignant mesothelioma 60 | 3,232
Astrocytoma, Pilocytic 58 | 3,081
Breast cancer 58 | 3,578
lung adenocarcinoma 56 | 2,716
lung carcinoma 55 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 54 | 2,989
oligodendroglioma 54 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 51 | 2,955
invasive ductal carcinoma 50 | 2,951
non-small cell lung cancer 48 | 2,890
subependymal giant cell astrocytoma 48 | 2,287
Epilepsy 47 | 792
astrocytic glioma 46 | 2,597
pancreatic cancer 46 | 2,398
interstitial cystitis 42 | 2,312
Autosomal recessive predisposition 41 | 1,442
Schizophrenia 40 | 1,160
pituitary cancer 37 | 1,972
ductal carcinoma in situ 36 | 1,745
cystic fibrosis 34 | 1,696
Hypertension 32 | 396
Intellectual disability 32 | 1,016
adrenocortical carcinoma 32 | 1,428
colon cancer 31 | 1,478
diabetes mellitus 31 | 1,728
breast carcinoma 29 | 1,638
Pick disease 28 | 1,894
tuberculosis 28 | 2,010
Multiple Sclerosis 27 | 540
ulcerative colitis 27 | 1,819
Alzheimer's disease 26 | 658
Kidney disease 26 | 430
Seizures 26 | 596
Bipolar Disorder 25 | 666
Dull intelligence 25 | 645
Endometriosis 25 | 540
Low intelligence 25 | 645
Mental Retardation 25 | 645
Mental deficiency 25 | 645
Poor school performance 25 | 645
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,962
Infertility 24 | 188
Autistic Disorder 21 | 364
Cognitive delay 21 | 608
Global developmental delay 21 | 608
Mental and motor retardation 21 | 608
group 4 medulloblastoma 21 | 1,855
Atopic dermatitis 20 | 952
Depressive disorder 20 | 409
Melanoma 20 | 711
Obesity 20 | 678
Heart disease 19 | 306
Hypertensive disease 19 | 292
Rheumatoid arthritis 19 | 1,191
Hypokalemia 18 | 52
nasopharyngeal carcinoma 18 | 1,058
primary pancreatic ductal adenocarcinoma 18 | 1,109
Atrial Fibrillation 17 | 124
Eaton-Lambert syndrome 17 | 40
Liver Cirrhosis, Experimental 17 | 769
Long QT syndrome 17 | 39
Parkinson's disease 17 | 392
Vascular disease 17 | 319
non primary Sjogren syndrome sicca 17 | 891
Alcoholic Intoxication, Chronic 16 | 289
Breast Neoplasms 16 | 445
Diarrhea 16 | 253
Failure to gain weight 16 | 365
Mammary Neoplasms 16 | 425
Mental Depression 16 | 333
Pediatric failure to thrive 16 | 365
Short stature 16 | 531
Skin cancer 16 | 469
cutaneous lupus erythematosus 16 | 1,057
pediatric high grade glioma 16 | 1,064
Toxic encephalopathy 15 | 141
active Crohn's disease 15 | 922
gastric carcinoma 15 | 807
Metabolic acidosis 14 | 90
Muscle hypotonia 14 | 571
Small head 14 | 374
astrocytoma 14 | 1,146
nephrosclerosis 14 | 333
progressive supranuclear palsy 14 | 676
spina bifida 14 | 1,074

Tissue

Endocrine System 246 | 18,159
Digestive Tract 236 | 17,369
Female tissues 229 | 17,400
Nervous System 229 | 16,725
Skin and soft tissues 227 | 17,230
Urinary Tract 224 | 16,678
Male tissues 223 | 17,142
Liver and Pancreas 221 | 16,750
Blood and immune system 213 | 16,909
Respiratory system 202 | 16,393
Cardiovascular System 179 | 15,192

Target Family

Non-IDG 80 | 12,091
Ion Channel 69 | 344
Transporter 49 | 473
Kinase 26 | 634
Enzyme 21 | 4,145
Transcription Factor 7 | 1,400
GPCR 4 | 408

Jensen-TM Tissue

BTO:0000964 256 | 256
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Electrogenic sodium bicarbonate cotransporter 1 SLC4A4 Tbio Transporter -2.63743 436.2 124
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
Solute carrier family 12 member 7 SLC12A7 Tbio Transporter -1.46102 28.2 156
Tetraspanin-16 TSPAN16 Tdark Non-IDG -1.99505 87.0 42
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Gap junction alpha-3 protein GJA3 Tbio Non-IDG -2.14059 135.1 171
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Solute carrier family 12 member 1 SLC12A1 Tclin Transporter -2.37125 226.3 178
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.73498 53.1 39
Serine/threonine-protein kinase 24 STK24 Tchem Kinase -2.24110 132.9 243