Development Level

Tbio 76 | 10,625
Tchem 11 | 1,890
Tclin 7 | 602
Tdark 5 | 7,003

Collection

GPCR: IDG Consortium (Complete/Control) 1 | 24

IMPC Phenotype

abnormal bone structure 3 | 131
increased CD4-positive, alpha ... 2 | 15
abnormal coat-hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal limb bud morphology 1 | 15
abnormal placenta morphology 1 | 4
abnormal seminal vesicle morph... 1 | 47
abnormal testis morphology 1 | 30
decreased B cell number 1 | 30
decreased CD4-positive, CD25-p... 1 | 24
decreased CD8-positive, naive ... 1 | 5
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased effector memory CD8-... 1 | 24
decreased gamma-delta T cell n... 1 | 18
decreased heart rate 1 | 10
decreased mature B cell number 1 | 25
embryonic lethality prior to t... 1 | 187
enlarged testis 1 | 1
female infertility 1 | 34
hemorrhage 1 | 12
increased KLRG1+ CD4 alpha bet... 1 | 5
increased KLRG1+ CD8 alpha bet... 1 | 2
increased KLRG1-positive CD4-n... 1 | 1
increased KLRG1-positive CD4-p... 1 | 3
increased KLRG1-positive NK ce... 1 | 9
increased KLRG1-positive T-hel... 1 | 2
increased KLRG1-positive gamma... 1 | 2
increased Ly6C low monocyte nu... 1 | 8
increased NK cell number 1 | 19
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating calcium ... 1 | 32
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
increased memory CD4-positive,... 1 | 3
increased memory-marker CD4-ne... 1 | 1
increased monocyte cell number 1 | 27
increased myeloid cell number 1 | 2
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
prenatal lethality prior to he... 1 | 64
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
prolonged RR interval 1 | 2
small testis 1 | 37

Disease

osteosarcoma 64 | 7,933
psoriasis 50 | 6,685
interstitial cystitis 42 | 2,299
Cancer 40 | 2,346
ovarian cancer 36 | 8,491
primary Sjogren syndrome 33 | 788
ulcerative colitis 32 | 2,087
cutaneous lupus erythematosus 27 | 1,056
lung cancer 27 | 4,473
lung carcinoma 22 | 2,844
medulloblastoma, large-cell 22 | 6,234
invasive ductal carcinoma 20 | 2,950
Rheumatoid Arthritis 19 | 1,170
nasopharyngeal carcinoma 19 | 1,056
Lymphoma 18 | 57
glioblastoma 18 | 5,572
tuberculosis 17 | 1,563
Breast cancer 16 | 3,098
Hypersensitivity reaction type II disease 16 | 235
adult high grade glioma 16 | 2,148
lung adenocarcinoma 15 | 2,714
malignant mesothelioma 15 | 3,163
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,956
ductal carcinoma in situ 13 | 1,745
group 4 medulloblastoma 13 | 1,875
oligodendroglioma 13 | 2,849
pancreatic cancer 13 | 2,300
Multiple Sclerosis 12 | 498
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
non-small cell lung cancer 12 | 2,798
subependymal giant cell astrocytoma 12 | 2,287
chronic lymphocytic leukemia 11 | 244
colon cancer 11 | 1,475
primitive neuroectodermal tumor 11 | 3,031
pilocytic astrocytoma 10 | 3,086
Asthma 9 | 349
Common variable immunodeficiency 9 | 98
Crohn's disease 9 | 304
diabetes mellitus 9 | 1,663
systemic lupus erythematosus 9 | 172
Leukemia 8 | 88
active Crohn's disease 8 | 918
atypical teratoid / rhabdoid tumor 8 | 4,369
cystic fibrosis 8 | 1,670
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
pediatric high grade glioma 8 | 2,712
Carcinoma 7 | 2,147
Celiac disease 7 | 112
Lupus Erythematosus, Systemic 7 | 73
Lupus erythematosus 7 | 80
Waldenstrons macroglobulinemia 7 | 764
astrocytoma 7 | 1,493
chronic lymphosyte leukemia 7 | 232
ependymoma 7 | 2,514
head and neck cancer and chronic obstructive pulmonary disease 7 | 237
periodontitis 7 | 269
pituitary cancer 7 | 1,972
Agammaglobulinemia 6 | 24
Amebiasis 6 | 22
IGA Glomerulonephritis 6 | 454
mucosa-associated lymphoid tissue lymphoma 6 | 480
pancreatic carcinoma 6 | 567
primary pancreatic ductal adenocarcinoma 6 | 1,271
sarcoidosis 6 | 368
spina bifida 6 | 1,064
tuberculosis and treatment for 3 months 6 | 327
Adult T-Cell Lymphoma/Leukemia 5 | 30
Allergic hypersensitivity disease 5 | 123
Atopic dermatitis 5 | 944
Inflammatory bowel disease 5 | 142
Pick disease 5 | 1,893
astrocytic glioma 5 | 2,241
breast carcinoma 5 | 1,614
group 3 medulloblastoma 5 | 2,254
juvenile dermatomyositis 5 | 1,189
non-small cell lung carcinoma 5 | 413
posterior fossa group B ependymoma 5 | 1,530
Dermatitis 4 | 141
Diarrhea 4 | 155
Hepatitis B 4 | 103
Human immunodeficiency virus infectious disease 4 | 129
Intellectual disability 4 | 573
Megaloblastic anemia 4 | 18
Obesity 4 | 616
Peripheral Neuropathy 4 | 303
Precursor Cell Lymphoblastic Leukemia Lymphoma 4 | 42
Primary biliary cirrhosis 4 | 45
Systemic scleroderma 4 | 66
acute myeloid leukemia 4 | 785
aldosterone-producing adenoma 4 | 664
atypical teratoid/rhabdoid tumor 4 | 1,095
chronic rhinosinusitis 4 | 512
gastric carcinoma 4 | 832
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
progressive supranuclear palsy 4 | 674
urothelial carcinoma 4 | 318
Juvenile arthritis 3 | 124
dermatomyositis 3 | 966
hepatocellular carcinoma 3 | 550
posterior fossa group A ependymoma 3 | 1,511

Tissue

Blood and immune system 93 | 17,994
Digestive Tract 93 | 18,472
Female tissues 93 | 18,646
Endocrine System 92 | 18,511
Urinary Tract 92 | 18,443
Liver and Pancreas 91 | 18,135
Nervous System 91 | 18,560
Skin and soft tissues 91 | 18,114
Male tissues 89 | 17,968
Cardiovascular System 88 | 17,957
Respiratory system 88 | 17,483

Target Family

Non-IDG 65 | 11,969
Transcription Factor 15 | 1,400
Enzyme 7 | 4,146
GPCR 5 | 408
Kinase 3 | 634
Transporter 2 | 473
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

Jensen-TM Tissue

B-lymphocyte 99 | 99
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium-dependent proline transporter SLC6A7 Tchem Transporter -2.09456 130.4 33
Sialic acid-binding Ig-like lectin 12 SIGLEC12 Tbio Non-IDG -2.35522 224.6 122
Serpin A9 SERPINA9 Tbio Non-IDG -1.93591 84.3 121
AT-rich interactive domain-containing protein 3A ARID3A Tbio Transcription Factor -2.07434 111.0 153
P2Y purinoceptor 8 P2RY8 Tbio GPCR -1.00631 7.92 122
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.84608 77.3 159
Interleukin-7 receptor subunit alpha IL7R Tbio Non-IDG -2.76199 528.6 688
Ig lambda-6 chain C region IGLC6 Tdark Non-IDG -1.81183 228.7 0
Protein artemis DCLRE1C Tbio Non-IDG -2.25361 45.4 225
Inducible T-cell costimulator ICOS Tbio Non-IDG -1.52153 31.7 495