Development Level

Tbio 21 | 11,445
Tdark 6 | 6,588
Tchem 3 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased fasted circulating g... 2 | 65
decreased hematocrit 2 | 46
enlarged heart 2 | 210
increased grip strength 2 | 41
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal placement of pupils 1 | 6
abnormal retinal vasculature m... 1 | 27
abnormal spleen morphology 1 | 55
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
cleft palate 1 | 8
decreased body length 1 | 101
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased urine creatinine lev... 1 | 3
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
hydrometra 1 | 53
hyperactivity 1 | 148
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
increased vertical activity 1 | 24
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 16 | 11,493
atypical teratoid / rhabdoid tumor 8 | 5,112
group 3 medulloblastoma 8 | 4,104
medulloblastoma, large-cell 8 | 6,241
psoriasis 8 | 6,694
Breast cancer 7 | 3,578
glioblastoma 7 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
osteosarcoma 7 | 7,950
Kidney cancer 6 | 2,613
ependymoma 6 | 4,679
Cancer 5 | 2,499
adult high grade glioma 5 | 3,801
malignant mesothelioma 5 | 3,232
ovarian cancer 5 | 8,520
pituitary cancer 5 | 1,972
Astrocytoma, Pilocytic 4 | 3,081
group 4 medulloblastoma 4 | 1,855
lung cancer 4 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
ulcerative colitis 4 | 1,819
3MC syndrome 3 | 6
Dull intelligence 3 | 645
Infertility 3 | 188
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Male infertility 3 | 206
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Orbital separation excessive 3 | 244
Pick disease 3 | 1,894
Poor school performance 3 | 645
Progressive relapsing multiple sclerosis 3 | 19
Sensorineural Hearing Loss (disorder) 3 | 284
astrocytic glioma 3 | 2,597
fibroadenoma 3 | 559
lung adenocarcinoma 3 | 2,716
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Anteverted nostril 2 | 191
Attention deficit hyperactivity disorder 2 | 278
Autosomal recessive predisposition 2 | 1,442
Blepharoptosis 2 | 231
Broad flat nasal bridge 2 | 236
Chagas disease 2 | 39
Chikungunya 2 | 16
Cleft Lip 2 | 141
Cleft Palate 2 | 271
Conductive hearing loss 2 | 123
Congenital deafness 2 | 185
Coronal craniosynostosis 2 | 14
Craniosynostosis 2 | 74
Curvature of spine 2 | 282
Deafness 2 | 198
Endometriosis 2 | 540
Glaucoma 2 | 239
Hearing Loss, Partial 2 | 185
Highly variable severity 2 | 157
Holoprosencephaly 2 | 56
Hypertensive disease 2 | 292
Increase in blood pressure 2 | 119
Kidney disease 2 | 430
Lordosis 2 | 54
Low Vision 2 | 174
Lymphogranuloma venereum 2 | 11
Nasal bridge wide 2 | 236
Ophthalmoplegia 2 | 106
Optic Atrophy 2 | 242
Periodontal disease 2 | 40
Schizophrenia 2 | 1,160
Skull malformation 2 | 38
Underdeveloped brows 2 | 38
Underdeveloped supraorbital ridges 2 | 38
Variable expressivity 2 | 157
Visual Impairment 2 | 174
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
hearing impairment 2 | 199
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
non-small cell lung cancer 2 | 2,890
non-small cell lung carcinoma 2 | 317
subependymal giant cell astrocytoma 2 | 2,287
Asymmetry of the posterior cranium 1 | 20
Coenurosis 1 | 6
Colitis, Ulcerative 1 | 59
DEAFNESS, NONSYNDROMIC SENSORINEURAL, MITOCHONDRIAL 1 | 4
Decreased amplitudes on flash visual electroretinogram 1 | 13
Decreased visual acuity, slowly progressive 1 | 13
Downturned corners of mouth 1 | 48
Facial asymmetry 1 | 32
Flattening of head 1 | 20
Opisthorchiasis 1 | 15
Peripheral Nervous System Diseases 1 | 52
Plagiocephaly 1 | 20
Plagiocephaly, Nonsynostotic 1 | 20
Rhomboid shaped head 1 | 20
Slow decrease in visual acuity 1 | 13

Tissue

Endocrine System 29 | 18,159
Blood and immune system 26 | 16,909
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Nervous System 26 | 16,725
Skin and soft tissues 26 | 17,230
Digestive Tract 25 | 17,369
Male tissues 25 | 17,142
Respiratory system 25 | 16,393
Urinary Tract 24 | 16,678
Cardiovascular System 23 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 11 | 4,145
Transcription Factor 4 | 1,400
GPCR 1 | 408
Kinase 1 | 634

Jensen-TM Tissue

Ascidian 30 | 30
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX6 TBX6 Tbio Transcription Factor -1.78720 63.0 315
Coiled-coil domain-containing protein 63 CCDC63 Tbio Non-IDG -0.89447 7.72 106
Radial spoke head 1 homolog RSPH1 Tbio Non-IDG -1.32379 19.1 52
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
Uncharacterized protein C4orf17 C4orf17 Tdark Non-IDG 0.70 0.15 34
Ovochymase-1 OVCH1 Tdark Enzyme -0.28473 2.27 57
Cytochrome c oxidase subunit 1 MT-CO1 Tchem Enzyme -3.69205 4610.4 141
Mannan-binding lectin serine protease 2 MASP2 Tbio Enzyme -2.24966 184.0 195
RPE-retinal G protein-coupled receptor RGR Tbio GPCR -1.35988 26.3 144
Dystrotelin DYTN Tdark Non-IDG -0.09691 0.91 64