Development Level

Tbio 24 | 11,445
Tdark 10 | 6,588
Tchem 4 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
decreased circulating alkaline... 2 | 46
decreased vertical activity 2 | 208
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
convulsive seizures 1 | 13
decreased basophil cell number 1 | 16
decreased cardiac output 1 | 3
decreased circulating alanine ... 1 | 47
decreased circulating creatini... 1 | 39
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased body length 1 | 32
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
thin ventricular wall 1 | 24

Disease

osteosarcoma 20 | 7,950
ovarian cancer 19 | 8,520
Carcinoma 17 | 11,493
medulloblastoma, large-cell 11 | 6,241
group 3 medulloblastoma 10 | 4,104
psoriasis 9 | 6,694
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
glioblastoma 7 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
invasive ductal carcinoma 7 | 2,951
primitive neuroectodermal tumor 7 | 3,035
Breast cancer 6 | 3,578
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
lung cancer 6 | 4,740
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
Astrocytoma, Pilocytic 4 | 3,081
ductal carcinoma in situ 4 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
Atopic dermatitis 3 | 952
Multiple myeloma 3 | 1,332
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
non-small cell lung cancer 3 | 2,890
posterior fossa group B ependymoma 3 | 416
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Allergic hypersensitivity disease 2 | 126
Allergic rhinitis 2 | 94
Asthma 2 | 385
Bipolar Disorder 2 | 666
Cerebellar Ataxia 2 | 304
Dementia 2 | 175
Depressive disorder 2 | 409
Dystonia 2 | 164
Hermansky-Pudlak syndrome 2 | 42
Kidney cancer 2 | 2,613
Lactic acidosis 2 | 51
Leigh disease 2 | 100
Male infertility 2 | 206
Mitochondrial Myopathies 2 | 21
Myopathy 2 | 185
Neuropathy 2 | 261
Nystagmus 2 | 317
Parkinson's disease 2 | 392
Peripheral Neuropathy 2 | 134
Polyneuropathy 2 | 64
Retinitis Pigmentosa 2 | 226
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
active ulcerative colitis 2 | 764
astrocytoma 2 | 1,146
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074
Abnormal color vision 1 | 31
Abnormality of thalamus morphology 1 | 2
Actinic keratosis 1 | 21
Aggressive systemic mastocytosis 1 | 20
Blindness, Cortical 1 | 24
Cervical Dystonia 1 | 26
Clonus 1 | 18
Color vision defect 1 | 33
Color vision defect, severe 1 | 31
Cortical visual impairment 1 | 24
Cytochrome-c Oxidase Deficiency 1 | 17
Episodic vomiting 1 | 10
Frequent vomiting 1 | 10
Hemiparesis 1 | 34
Iris disease 1 | 10
Leukemia, Megakaryoblastic, of Down Syndrome 1 | 8
Mitochondrial respiratory chain defects 1 | 15
Nystagmus, continuous pendular 1 | 14
Pendular Nystagmus 1 | 14
Plague 1 | 19
Reduced visual acuity 1 | 63
Riley-Day syndrome 1 | 11
Sensorineural hearing loss, bilateral 1 | 18
Spasmodic torticollis 1 | 17
Spinocerebellar ataxia type 13 1 | 5
Torticollis 1 | 18
cone-rod dystrophy 1 | 59
cytochrome-c oxidase deficiency disease 1 | 19

Tissue

Endocrine System 39 | 18,159
Digestive Tract 37 | 17,369
Male tissues 37 | 17,142
Skin and soft tissues 37 | 17,230
Blood and immune system 36 | 16,909
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Nervous System 36 | 16,725
Respiratory system 36 | 16,393
Urinary Tract 36 | 16,678
Cardiovascular System 35 | 15,192

Target Family

Non-IDG 22 | 12,091
Enzyme 11 | 4,145
GPCR 2 | 408
Transcription Factor 2 | 1,400
Nuclear Receptor 1 | 48
Transporter 1 | 473

Jensen-TM Tissue

Anther 39 | 39
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome c oxidase assembly protein COX11, mitochondrial COX11 Tbio Enzyme -1.42359 24.4 86
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.33263 208.9 148
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 AGAP3 Tdark Enzyme -0.29800 2.17 132
Translation machinery-associated protein 7 TMA7 Tdark Non-IDG -0.57787 4.42 13
SMC5-SMC6 complex localization factor protein 2 SLF2 Tbio Non-IDG -0.68501 3.77 14
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.55611 364.6 174
Glycerol-3-phosphate acyltransferase 3 GPAT3 Tbio Enzyme -1.54939 32.0 138
Sterile alpha motif domain-containing protein 5 SAMD5 Tdark Non-IDG -0.62960 4.04 3
Cytochrome c oxidase assembly protein COX19 COX19 Tdark Enzyme -0.95661 8.30 46
Cleavage stimulation factor subunit 3 CSTF3 Tbio Non-IDG -1.06216 10.1 160