Development Level

Tbio 17 | 11,445
Tchem 16 | 1,598
Tclin 4 | 613

IMPC Phenotype

decreased basophil cell number 2 | 16
decreased blood urea nitrogen ... 2 | 51
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal hair texture 1 | 4
abnormal incisor morphology 1 | 4
abnormal limb morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal tail morphology 1 | 25
abnormal tooth morphology 1 | 24
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased lactate dehydrogenas... 1 | 16
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
hemorrhage 1 | 23
increased blood urea nitrogen ... 1 | 48
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
polycystic kidney 1 | 15
premature death 1 | 5
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2
unresponsive to tactile stimul... 1 | 8

Disease

Alzheimer's disease 35 | 658
Carcinoma 28 | 11,493
Dementia 22 | 175
osteosarcoma 22 | 7,950
ovarian cancer 22 | 8,520
medulloblastoma, large-cell 20 | 6,241
glioblastoma 19 | 5,792
Toxic encephalopathy 15 | 141
ependymoma 15 | 4,679
lung cancer 15 | 4,740
Astrocytoma, Pilocytic 14 | 3,081
atypical teratoid / rhabdoid tumor 14 | 5,112
group 3 medulloblastoma 14 | 4,104
psoriasis 14 | 6,694
Alzheimer Disease 13 | 83
Amyloidosis 13 | 67
Cancer 13 | 2,499
invasive ductal carcinoma 13 | 2,951
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
Neurodegenerative disease 12 | 414
Parkinson's disease 12 | 392
adult high grade glioma 12 | 3,801
Brain disease 11 | 96
Schizophrenia 11 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
oligodendroglioma 11 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
pancreatic cancer 10 | 2,398
subependymal giant cell astrocytoma 10 | 2,287
Amyotrophic lateral sclerosis 9 | 451
Pick disease 9 | 1,894
cutaneous lupus erythematosus 9 | 1,057
juvenile dermatomyositis 9 | 1,187
Breast cancer 8 | 3,578
Depressive disorder 8 | 409
astrocytic glioma 8 | 2,597
lung adenocarcinoma 8 | 2,716
Bipolar Disorder 7 | 666
Cerebrovascular disease 7 | 238
Down syndrome 7 | 499
Duchenne muscular dystrophy 7 | 601
Nerve Degeneration 7 | 121
Seizures 7 | 596
acute quadriplegic myopathy 7 | 1,158
cystic fibrosis 7 | 1,696
dermatomyositis 7 | 966
diabetes mellitus 7 | 1,728
ulcerative colitis 7 | 1,819
Deglutition Disorders 6 | 132
Disease Models, Animal 6 | 155
Frontotemporal dementia 6 | 51
Learning Disorders 6 | 29
Liver Cirrhosis, Experimental 6 | 769
Memory Disorders 6 | 40
Neurodegenerative Disorders 6 | 79
Neurofibrillary degeneration (morphologic abnormality) 6 | 9
Obesity 6 | 678
Parkinsonian Disorders 6 | 56
astrocytoma 6 | 1,146
interstitial cystitis 6 | 2,312
non-small cell lung cancer 6 | 2,890
primitive neuroectodermal tumor 6 | 3,035
progressive supranuclear palsy 6 | 676
tuberculosis 6 | 2,010
Anxiety 5 | 136
Anxiety disease 5 | 113
Aphasia 5 | 26
Breast Neoplasms 5 | 445
Cognition Disorders 5 | 32
Dysarthria 5 | 192
Epilepsy 5 | 792
Forgetful 5 | 40
Mammary Neoplasms 5 | 425
Memory Loss 5 | 40
Memory impairment 5 | 40
Multiple Sclerosis 5 | 540
Multiple myeloma 5 | 1,332
Myoclonus 5 | 74
Pick's disease 5 | 15
Prostatic Neoplasms 5 | 495
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Aggressive behavior 4 | 75
Aggressive reaction 4 | 75
Gliosis 4 | 56
Hypertension 4 | 396
Kidney cancer 4 | 2,613
Kidney disease 4 | 430
Muscle Spasticity 4 | 195
Neuroblastoma 4 | 80
Personality change 4 | 23
Physical aggression 4 | 76
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064

Tissue

Blood and immune system 36 | 16,909
Digestive Tract 36 | 17,369
Endocrine System 36 | 18,159
Female tissues 36 | 17,400
Liver and Pancreas 36 | 16,750
Nervous System 36 | 16,725
Skin and soft tissues 36 | 17,230
Urinary Tract 36 | 16,678
Cardiovascular System 35 | 15,192
Male tissues 35 | 17,142
Respiratory system 35 | 16,393

Target Family

Non-IDG 22 | 12,091
Enzyme 12 | 4,145
Transporter 2 | 473
Kinase 1 | 634

Jensen-TM Tissue

Amyloid plaque 37 | 37
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Alpha-1-antichymotrypsin SERPINA3 Tbio Non-IDG -2.94780 812.7 276
Insulin-degrading enzyme IDE Tchem Enzyme -2.57779 392.8 331
Gamma-secretase subunit PEN-2 PSENEN Tchem Enzyme -2.84761 677.3 204
Alternative prion protein PRNP Tbio Non-IDG -3.45326 5611.1 0
Amyloid-like protein 1 APLP1 Tbio Non-IDG -1.88769 62.6 162
Sodium- and chloride-dependent betaine transporter SLC6A12 Tchem Transporter -2.34582 212.0 104
Collagen alpha-1(XXV) chain COL25A1 Tbio Non-IDG -0.99093 10.6 119
Reticulon-3 RTN3 Tbio Non-IDG -1.53823 40.0 137