Development Level

Tbio 559 | 10,625
Tchem 253 | 1,890
Tclin 154 | 602
Tdark 10 | 7,003

Collection

Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

preweaning lethality, complete... 36 | 633
decreased lean body mass 19 | 195
preweaning lethality, incomple... 19 | 260
decreased bone mineral content 17 | 157
abnormal behavior 16 | 226
embryonic lethality prior to t... 15 | 187
decreased body weight 14 | 174
decreased total body fat amoun... 13 | 186
hypoactivity 11 | 89
decreased bone mineral density 10 | 126
decreased grip strength 10 | 123
increased circulating alkaline... 10 | 119
increased lean body mass 10 | 107
decreased circulating choleste... 9 | 85
abnormal bone structure 8 | 131
embryonic lethality prior to o... 8 | 148
increased circulating HDL chol... 8 | 63
increased or absent threshold ... 8 | 128
abnormal embryo size 7 | 112
decreased circulating HDL chol... 7 | 77
decreased circulating alanine ... 7 | 53
decreased heart weight 7 | 44
increased circulating choleste... 7 | 53
increased mean corpuscular hem... 7 | 93
abnormal lens morphology 6 | 73
abnormal retina morphology 6 | 100
decreased body length 6 | 108
decreased circulating LDL chol... 6 | 37
decreased circulating glucose ... 6 | 121
improved glucose tolerance 6 | 56
increased grip strength 6 | 83
increased total body fat amoun... 6 | 57
male infertility 6 | 62
short tibia 6 | 82
tremors 6 | 34
abnormal gait 5 | 51
abnormal sleep behavior 5 | 63
abnormal tooth morphology 5 | 24
decreased circulating creatini... 5 | 31
decreased circulating insulin ... 5 | 75
decreased circulating triglyce... 5 | 83
decreased erythrocyte cell num... 5 | 43
decreased prepulse inhibition 5 | 52
enlarged heart 5 | 111
increased body weight 5 | 42
increased circulating sodium l... 5 | 71
increased circulating triglyce... 5 | 24
increased fasted circulating g... 5 | 68
increased mean corpuscular vol... 5 | 91
abnormal behavioral response t... 4 | 52
abnormal coat-hair pigmentatio... 4 | 54
abnormal epididymis morphology 4 | 31
abnormal snout morphology 4 | 18
decreased blood urea nitrogen ... 4 | 31
decreased circulating alkaline... 4 | 41
decreased lactate dehydrogenas... 4 | 14
female infertility 4 | 34
impaired glucose tolerance 4 | 52
impaired righting response 4 | 19
increased blood urea nitrogen ... 4 | 44
increased circulating potassiu... 4 | 31
limb grasping 4 | 35
abnormal femur morphology 3 | 14
abnormal forebrain development 3 | 18
abnormal hindbrain development 3 | 24
abnormal humerus morphology 3 | 11
abnormal midbrain development 3 | 22
abnormal neural tube closure 3 | 37
abnormal optic disc morphology 3 | 10
abnormal retinal pigmentation 3 | 61
abnormal retinal vasculature m... 3 | 15
abnormal seminal vesicle morph... 3 | 47
abnormal testis morphology 3 | 30
cardiovascular system phenotyp... 3 | 35
cataract 3 | 26
decreased circulating aspartat... 3 | 27
decreased circulating calcium ... 3 | 33
decreased circulating free fat... 3 | 39
decreased circulating phosphat... 3 | 15
decreased effector memory CD8-... 3 | 24
decreased monocyte cell number 3 | 28
decreased rib number 3 | 59
hydrops fetalis 3 | 22
hyperactivity 3 | 108
increased bone mineral content 3 | 92
increased circulating alanine ... 3 | 11
increased circulating serum al... 3 | 25
increased circulating total pr... 3 | 20
increased exploration in new e... 3 | 56
increased hematocrit 3 | 36
increased hemoglobin content 3 | 45
increased respiratory quotient 3 | 12
narrow eye opening 3 | 15
straub tail 3 | 26
thrombocytopenia 3 | 46
abnormal head morphology 2 | 10
decreased circulating iron lev... 2 | 25
increased circulating aspartat... 2 | 17
increased circulating chloride... 2 | 43
small testis 2 | 37

Disease

Cancer 626 | 2,346
psoriasis 487 | 6,685
ovarian cancer 462 | 8,491
osteosarcoma 394 | 7,933
glioblastoma 385 | 5,572
diabetes mellitus 371 | 1,663
lung cancer 356 | 4,473
medulloblastoma, large-cell 355 | 6,234
atypical teratoid / rhabdoid tumor 260 | 4,369
pilocytic astrocytoma 254 | 3,086
lung carcinoma 253 | 2,844
invasive ductal carcinoma 245 | 2,950
malignant mesothelioma 242 | 3,163
Breast cancer 232 | 3,098
intraductal papillary-mucinous neoplasm (IPMN) 230 | 3,289
non-small cell lung cancer 226 | 2,798
lung adenocarcinoma 225 | 2,714
Kidney disease 219 | 397
intraductal papillary-mucinous adenoma (IPMA) 219 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 215 | 2,988
oligodendroglioma 213 | 2,849
pancreatic cancer 208 | 2,300
pediatric high grade glioma 204 | 2,712
ulcerative colitis 203 | 2,087
Carcinoma 200 | 2,147
interstitial cystitis 200 | 2,299
Obesity 183 | 616
primitive neuroectodermal tumor 182 | 3,031
pituitary cancer 175 | 1,972
Rheumatoid Arthritis 174 | 1,170
cystic fibrosis 168 | 1,670
tuberculosis 167 | 1,563
Arthritis 165 | 248
subependymal giant cell astrocytoma 161 | 2,287
breast carcinoma 160 | 1,614
Hypertension 157 | 293
ductal carcinoma in situ 157 | 1,745
Heart disease 153 | 279
Hypersensitivity reaction type II disease 150 | 235
Cerebrovascular disease 145 | 231
Liver disease 144 | 219
ependymoma 144 | 2,514
Alzheimer's disease 143 | 644
astrocytoma 136 | 1,493
colon cancer 136 | 1,475
Anemia 133 | 252
posterior fossa group A ependymoma 130 | 1,511
pancreatic ductal adenocarcinoma liver metastasis 129 | 1,795
adult high grade glioma 128 | 2,148
Atherosclerosis 123 | 275
astrocytic glioma 123 | 2,241
Mammary Neoplasms 122 | 410
Vascular disease 122 | 281
cutaneous lupus erythematosus 121 | 1,056
Multiple Sclerosis 120 | 498
Schizophrenia 120 | 503
adrenocortical carcinoma 119 | 1,427
Coronary artery disease 118 | 240
group 4 medulloblastoma 118 | 1,875
dermatomyositis 117 | 966
group 3 medulloblastoma 112 | 2,254
Asthma 108 | 349
sonic hedgehog group medulloblastoma 108 | 1,482
Prostatic Neoplasms 106 | 471
Lung disease 102 | 136
Parkinson's disease 102 | 364
primary pancreatic ductal adenocarcinoma 100 | 1,271
medulloblastoma 98 | 1,524
Pick disease 97 | 1,893
Acquired immunodeficiency syndrome 95 | 164
acute quadriplegic myopathy 94 | 1,157
Atopic dermatitis 92 | 944
Epilepsy 92 | 346
nasopharyngeal carcinoma 92 | 1,056
Toxic encephalopathy 91 | 131
Uveitis 91 | 103
juvenile dermatomyositis 91 | 1,189
gastric carcinoma 88 | 832
Neurodegenerative disease 86 | 383
atypical teratoid/rhabdoid tumor 86 | 1,095
Dermatitis 84 | 141
Endometriosis 84 | 535
Autistic Disorder 82 | 320
Down syndrome 82 | 548
Multiple myeloma 82 | 1,327
Hypertensive disease 80 | 193
Ankylosing spondylitis 79 | 138
Duchenne muscular dystrophy 79 | 602
Hyperglycemia 78 | 120
Inflammatory bowel disease 78 | 142
Metabolic syndrome X 78 | 155
Adenoma 77 | 165
posterior fossa group B ependymoma 77 | 1,530
Diarrhea 76 | 155
Osteoporosis 75 | 259
esophageal adenocarcinoma 75 | 737
Stomach Neoplasms 74 | 282
Neuropathy 72 | 210
Lung Neoplasms 71 | 171
Human immunodeficiency virus infectious disease 70 | 129

Tissue

Nervous System 915 | 18,560
Endocrine System 914 | 18,511
Female tissues 914 | 18,646
Digestive Tract 913 | 18,472
Urinary Tract 909 | 18,443
Liver and Pancreas 901 | 18,135
Skin and soft tissues 901 | 18,114
Cardiovascular System 896 | 17,957
Blood and immune system 893 | 17,994
Male tissues 886 | 17,968
Respiratory system 876 | 17,483

Target Family

Non-IDG 524 | 11,969
Enzyme 194 | 4,146
Transcription Factor 100 | 1,400
Kinase 51 | 634
GPCR 31 | 408
Transporter 29 | 473
Ion Channel 22 | 341
Nuclear Receptor 13 | 48
Epigenetic 11 | 242
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Adult 976 | 976
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box/WD repeat-containing protein 2 FBXW2 Tbio Non-IDG -1.99707 87.2 90
Huntingtin HTT Tchem Non-IDG -3.32908 2140.8 521
E-selectin SELE Tchem Non-IDG -3.43650 2598.8 820
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.25806 19000.3 3336
Proto-oncogene Wnt-1 WNT1 Tbio Non-IDG -2.73870 492.7 294
High affinity nerve growth factor receptor NTRK1 Tchem Kinase -3.03552 1003.4 1000
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.34747 2121.3 411
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.85874 681.4 264
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.36387 2061.0 806
Hemoglobin subunit zeta HBZ Tbio Non-IDG -2.36868 235.4 158