Development Level

Tbio 625 | 11,445
Tchem 213 | 1,598
Tclin 167 | 613
Tdark 8 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 59 | 979
preweaning lethality, incomple... 33 | 499
embryonic lethality prior to t... 23 | 278
decreased vertical activity 18 | 208
decreased bone mineral content 17 | 151
abnormal behavior 15 | 298
abnormal embryo size 15 | 220
embryonic lethality prior to o... 15 | 239
increased total body fat amoun... 15 | 134
decreased lean body mass 14 | 135
abnormal bone structure 13 | 187
decreased bone mineral density 13 | 126
hypoactivity 13 | 132
decreased total body fat amoun... 11 | 207
enlarged heart 11 | 210
impaired glucose tolerance 11 | 75
increased circulating alkaline... 11 | 122
abnormal heart morphology 10 | 162
abnormal seminal vesicle morph... 10 | 114
decreased body weight 10 | 161
decreased circulating choleste... 10 | 93
improved glucose tolerance 9 | 79
increased startle reflex 9 | 112
decreased body length 8 | 101
decreased grip strength 8 | 116
edema 8 | 59
embryonic growth retardation 8 | 106
increased lean body mass 8 | 172
short tibia 8 | 97
small superior vagus ganglion 8 | 74
decreased circulating HDL chol... 7 | 68
decreased circulating LDL chol... 7 | 38
decreased mean corpuscular vol... 7 | 79
hyperactivity 7 | 148
increased bone mineral content 7 | 108
increased circulating HDL chol... 7 | 80
increased circulating sodium l... 7 | 71
increased monocyte cell number 7 | 63
male infertility 7 | 123
abnormal lens morphology 6 | 81
abnormal sleep behavior 6 | 70
abnormal testis morphology 6 | 43
cataract 6 | 92
decreased circulating creatini... 6 | 39
decreased circulating glucose ... 6 | 126
decreased erythrocyte cell num... 6 | 62
decreased heart weight 6 | 27
decreased lymphocyte cell numb... 6 | 83
increased lymphocyte cell numb... 6 | 32
increased mean corpuscular hem... 6 | 96
increased mean corpuscular vol... 6 | 92
prolonged ST segment 6 | 36
abnormal kidney morphology 5 | 65
decreased circulating alkaline... 5 | 46
decreased leukocyte cell numbe... 5 | 73
decreased neutrophil cell numb... 5 | 42
decreased prepulse inhibition 5 | 82
decreased startle reflex 5 | 75
female infertility 5 | 60
impaired righting response 5 | 26
increased circulating choleste... 5 | 66
increased circulating total pr... 5 | 28
increased heart weight 5 | 62
limb grasping 5 | 41
abnormal epididymis morphology 4 | 42
abnormal gait 4 | 69
abnormal retina morphology 4 | 71
decreased blood urea nitrogen ... 4 | 51
decreased circulating aspartat... 4 | 34
decreased circulating insulin ... 4 | 76
decreased circulating serum al... 4 | 82
decreased circulating triglyce... 4 | 79
decreased lactate dehydrogenas... 4 | 16
hydrometra 4 | 53
increased blood urea nitrogen ... 4 | 48
increased circulating chloride... 4 | 41
increased circulating triglyce... 4 | 42
increased fasted circulating g... 4 | 76
increased neutrophil cell numb... 4 | 46
increased or absent threshold ... 4 | 101
prolonged QT interval 4 | 38
small testis 4 | 58
tremors 4 | 39
abnormal coat-hair pigmentatio... 3 | 64
abnormal lung morphology 3 | 26
abnormal spleen morphology 3 | 55
abnormal vertebrae morphology 3 | 18
absent startle reflex 3 | 24
decreased circulating calcium ... 3 | 36
decreased eosinophil cell numb... 3 | 24
decreased fasted circulating g... 3 | 65
decreased hemoglobin content 3 | 68
decreased spleen weight 3 | 10
increased body weight 3 | 25
increased circulating iron lev... 3 | 30
increased circulating phosphat... 3 | 26
increased circulating serum al... 3 | 22
increased hemoglobin content 3 | 45
microphthalmia 3 | 26
prenatal lethality prior to he... 3 | 87

Disease

Carcinoma 672 | 11,493
Cancer 656 | 2,499
psoriasis 506 | 6,694
ovarian cancer 476 | 8,520
glioblastoma 416 | 5,792
osteosarcoma 412 | 7,950
diabetes mellitus 403 | 1,728
lung cancer 391 | 4,740
medulloblastoma, large-cell 372 | 6,241
atypical teratoid / rhabdoid tumor 327 | 5,112
ependymoma 313 | 4,679
Breast cancer 284 | 3,578
malignant mesothelioma 271 | 3,232
Schizophrenia 267 | 1,160
adult high grade glioma 265 | 3,801
Astrocytoma, Pilocytic 260 | 3,081
lung carcinoma 258 | 2,843
invasive ductal carcinoma 252 | 2,951
group 3 medulloblastoma 245 | 4,104
non-small cell lung cancer 236 | 2,890
lung adenocarcinoma 233 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 232 | 3,291
Kidney disease 227 | 430
pancreatic cancer 227 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 221 | 2,955
oligodendroglioma 220 | 2,850
intraductal papillary-mucinous carcinoma (IPMC) 218 | 2,989
Obesity 211 | 678
Autosomal recessive predisposition 209 | 1,442
tuberculosis 209 | 2,010
interstitial cystitis 205 | 2,312
Kidney cancer 204 | 2,613
Hypertension 198 | 396
primitive neuroectodermal tumor 186 | 3,035
pituitary cancer 181 | 1,972
Rheumatoid arthritis 180 | 1,191
ulcerative colitis 177 | 1,819
Arthritis 176 | 290
astrocytic glioma 175 | 2,597
subependymal giant cell astrocytoma 173 | 2,287
cystic fibrosis 171 | 1,696
breast carcinoma 170 | 1,638
Bipolar Disorder 167 | 666
Epilepsy 164 | 792
Heart disease 164 | 306
ductal carcinoma in situ 162 | 1,745
Depressive disorder 161 | 409
Anemia 158 | 365
Alzheimer's disease 156 | 658
Hypersensitivity reaction type II disease 156 | 253
Liver disease 154 | 237
Cerebrovascular disease 152 | 238
pancreatic ductal adenocarcinoma liver metastasis 149 | 1,962
colon cancer 140 | 1,478
Seizures 139 | 596
Coronary artery disease 134 | 268
Breast Neoplasms 133 | 445
Mammary Neoplasms 132 | 425
Liver Cirrhosis, Experimental 130 | 769
Multiple Sclerosis 130 | 540
Vascular disease 130 | 319
Atherosclerosis 128 | 291
Mental Depression 128 | 333
Intellectual disability 125 | 1,016
cutaneous lupus erythematosus 125 | 1,057
Hypertensive disease 119 | 292
Major Depressive Disorder 119 | 301
adrenocortical carcinoma 119 | 1,428
group 4 medulloblastoma 119 | 1,855
dermatomyositis 117 | 966
Prostatic Neoplasms 116 | 495
Short stature 114 | 531
Asthma 113 | 385
Parkinson's disease 110 | 392
Lung disease 103 | 142
astrocytoma 102 | 1,146
Toxic encephalopathy 101 | 141
Pick disease 100 | 1,894
Unipolar Depression 100 | 250
Diarrhea 99 | 253
Neurodegenerative disease 99 | 414
Atopic dermatitis 98 | 952
Acquired immunodeficiency syndrome 97 | 197
Osteoporosis 97 | 363
Dull intelligence 96 | 645
Low intelligence 96 | 645
Mental Retardation 96 | 645
Mental deficiency 96 | 645
Poor school performance 96 | 645
acute quadriplegic myopathy 96 | 1,158
Alcoholic Intoxication, Chronic 95 | 289
juvenile dermatomyositis 94 | 1,187
nasopharyngeal carcinoma 94 | 1,058
Melanoma 93 | 711
Cognitive delay 92 | 608
Global developmental delay 92 | 608
Mental and motor retardation 92 | 608
Autistic Disorder 90 | 364
Dermatitis 90 | 157
Neuropathy 89 | 261

Tissue

Endocrine System 921 | 18,159
Digestive Tract 905 | 17,369
Female tissues 898 | 17,400
Skin and soft tissues 890 | 17,230
Male tissues 874 | 17,142
Liver and Pancreas 871 | 16,750
Blood and immune system 869 | 16,909
Nervous System 865 | 16,725
Urinary Tract 860 | 16,678
Respiratory system 837 | 16,393
Cardiovascular System 751 | 15,192

Target Family

Non-IDG 532 | 12,091
Enzyme 210 | 4,145
Transcription Factor 106 | 1,400
Kinase 53 | 634
GPCR 32 | 408
Transporter 29 | 473
Ion Channel 26 | 344
Nuclear Receptor 13 | 48
Epigenetic 12 | 242

Jensen-TM Tissue

Adult 1,013 | 1,013
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Adipocyte 199 | 199
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
Doublesex- and mab-3-related transcription factor 1 DMRT1 Tbio Transcription Factor -2.31269 210.5 197
Dermatan-sulfate epimerase DSE Tbio Enzyme -2.57112 360.0 44
NUT family member 1 NUTM1 Tbio Non-IDG -2.63366 415.1 50
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.81752 661.7 128
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Neural retina-specific leucine zipper protein NRL Tbio Transcription Factor -2.46080 279.4 74
Gap junction delta-2 protein GJD2 Tbio Non-IDG -2.48933 326.9 192
Endoglin ENG Tbio Non-IDG -3.10482 1235.9 1622
Myocilin MYOC Tbio Non-IDG -2.65916 482.8 169