Development Level

Tbio 95 | 10,625
Tchem 67 | 1,890
Tclin 42 | 602
Tdark 3 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 11 | 633
abnormal bone structure 8 | 131
preweaning lethality, incomple... 7 | 260
abnormal bone mineralization 6 | 55
decreased bone mineral content 6 | 157
decreased lean body mass 6 | 195
abnormal behavior 5 | 226
decreased circulating LDL chol... 4 | 37
decreased grip strength 4 | 123
increased circulating alkaline... 4 | 119
increased circulating choleste... 4 | 53
increased heart weight 4 | 37
abnormal gait 3 | 51
abnormal retina morphology 3 | 100
decreased circulating serum al... 3 | 79
embryonic lethality prior to o... 3 | 148
embryonic lethality prior to t... 3 | 187
enlarged heart 3 | 111
hypoactivity 3 | 89
impaired glucose tolerance 3 | 52
improved glucose tolerance 3 | 56
increased circulating HDL chol... 3 | 63
increased circulating triglyce... 3 | 24
increased erythrocyte cell num... 3 | 26
increased total body fat amoun... 3 | 57
abnormal QRS complex 2 | 25
abnormal epididymis morphology 2 | 31
abnormal lens morphology 2 | 73
cataract 2 | 26
decreased NK cell number 2 | 16
decreased body weight 2 | 174
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating alkaline... 2 | 41
decreased circulating calcium ... 2 | 33
decreased fasted circulating g... 2 | 49
decreased monocyte cell number 2 | 28
decreased prepulse inhibition 2 | 52
decreased vertical activity 2 | 22
enlarged epididymis 2 | 27
hyperactivity 2 | 108
immune system phenotype 2 | 17
increased blood urea nitrogen ... 2 | 44
increased body weight 2 | 42
increased circulating LDL chol... 2 | 15
increased circulating amylase ... 2 | 13
increased circulating calcium ... 2 | 32
increased circulating creatini... 2 | 29
increased circulating free fat... 2 | 17
increased circulating serum al... 2 | 25
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 68
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
limb grasping 2 | 35
male infertility 2 | 62
short tibia 2 | 82
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal coping response 1 | 12
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal respiratory quotient 1 | 9
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal startle reflex 1 | 14
abnormal tooth morphology 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased Ly6C high monocyte n... 1 | 18
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 5
decreased circulating bilirubi... 1 | 14
decreased circulating sodium l... 1 | 18
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased neutrophil cell numb... 1 | 37
decreased pulmonary respirator... 1 | 4
enlarged spleen 1 | 26
female infertility 1 | 34
impaired righting response 1 | 19
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating magnesiu... 1 | 10
increased grip strength 1 | 83
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
premature death 1 | 5
straub tail 1 | 26

Disease

Cancer 103 | 2,346
psoriasis 103 | 6,685
ovarian cancer 84 | 8,484
glioblastoma 78 | 5,572
medulloblastoma, large-cell 74 | 6,234
Obesity 71 | 616
osteosarcoma 71 | 7,933
lung cancer 69 | 4,466
diabetes mellitus 67 | 1,663
Alzheimer's disease 62 | 644
atypical teratoid / rhabdoid tumor 60 | 4,369
Hypertension 59 | 287
pilocytic astrocytoma 55 | 3,086
Adenoma 53 | 165
Kidney disease 52 | 396
oligodendroglioma 51 | 2,849
Parkinson's disease 49 | 364
pediatric high grade glioma 49 | 2,712
malignant mesothelioma 48 | 3,162
lung carcinoma 47 | 2,844
Schizophrenia 46 | 501
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,956
Heart disease 44 | 279
Toxic encephalopathy 44 | 131
Cerebrovascular disease 42 | 231
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,988
pituitary cancer 41 | 1,972
Breast cancer 40 | 3,094
invasive ductal carcinoma 40 | 2,950
primitive neuroectodermal tumor 40 | 3,031
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,289
adrenocortical carcinoma 38 | 1,427
ependymoma 38 | 2,514
Hypertensive disease 37 | 193
Pick disease 37 | 1,893
lung adenocarcinoma 37 | 2,713
ulcerative colitis 37 | 2,087
non-small cell lung cancer 36 | 2,798
Cushing's syndrome 35 | 47
astrocytic glioma 33 | 2,241
astrocytoma 33 | 1,493
interstitial cystitis 33 | 2,299
pancreatic cancer 32 | 2,300
Dementia 31 | 129
Prostatic Neoplasms 31 | 471
colon cancer 30 | 1,475
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,795
subependymal giant cell astrocytoma 30 | 2,287
Atherosclerosis 29 | 275
Hyperglycemia 29 | 120
Autistic Disorder 28 | 320
Brain disease 28 | 83
Endometriosis 28 | 535
breast carcinoma 28 | 1,614
sonic hedgehog group medulloblastoma 28 | 1,482
Bipolar Disorder 27 | 266
Coronary artery disease 27 | 240
Metabolic syndrome X 27 | 155
Osteoporosis 27 | 257
cystic fibrosis 27 | 1,665
ductal carcinoma in situ 27 | 1,745
posterior fossa group B ependymoma 27 | 1,530
Asthma 26 | 349
Carcinoma 26 | 2,147
Cocaine-Related Disorders 26 | 88
Polycystic Ovary Syndrome 26 | 332
Arthritis 25 | 248
Diarrhea 25 | 155
Hypoglycemia 25 | 81
Major Depressive Disorder 25 | 106
Seizures 25 | 95
Hypotension 24 | 53
Liver disease 24 | 219
Mammary Neoplasms 24 | 410
Pain agnosia 24 | 99
Vascular disease 24 | 281
adult high grade glioma 24 | 2,148
medulloblastoma 24 | 1,524
Congenital adrenal hyperplasia 23 | 74
Epilepsy 23 | 346
Hypothyroidism 23 | 89
group 4 medulloblastoma 23 | 1,875
posterior fossa group A ependymoma 23 | 1,511
Down syndrome 22 | 548
Hyperinsulinism 22 | 63
Lung disease 22 | 132
Rheumatoid Arthritis 22 | 1,160
tuberculosis 22 | 1,557
Infertility 21 | 163
Inflammation 21 | 109
Pain 21 | 70
Pancreatitis 21 | 97
aldosterone-producing adenoma 21 | 664
Alcohol dependence 20 | 107
Heart failure 20 | 80
Hyperthyroidism 20 | 50
Hypogonadism 20 | 70
Neuropathy 20 | 210
Pituitary adenoma 20 | 35
Atopic dermatitis 19 | 944

Tissue

Female tissues 205 | 18,647
Endocrine System 204 | 18,512
Nervous System 204 | 18,561
Digestive Tract 203 | 18,473
Urinary Tract 202 | 18,444
Cardiovascular System 199 | 17,958
Liver and Pancreas 198 | 18,136
Skin and soft tissues 198 | 18,115
Blood and immune system 195 | 17,995
Male tissues 191 | 17,969
Respiratory system 190 | 17,484

Target Family

Non-IDG 106 | 11,971
Enzyme 50 | 4,146
GPCR 12 | 406
Kinase 10 | 634
Transporter 9 | 473
Nuclear Receptor 8 | 48
Transcription Factor 6 | 1,400
Ion Channel 4 | 341
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Adrenal gland 207 | 207
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Lymph node 206 | 206
Adipocyte 194 | 194
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glial cell line-derived neurotrophic factor GDNF Tbio Non-IDG -3.30206 2301.5 303
Nucleolar GTP-binding protein 1 GTPBP4 Tbio Non-IDG -3.21425 1443.3 95
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Cytochrome b561 CYB561 Tbio Non-IDG -1.41910 20.4 45
Cytochrome b5 CYB5A Tchem Non-IDG -3.24788 1711.2 249
Stathmin-2 STMN2 Tbio Non-IDG -1.95188 90.0 305