Development Level

Tbio 116 | 11,651
Tchem 54 | 1,388
Tclin 24 | 612
Tdark 5 | 6,593

Collection

GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

preweaning lethality, incomple... 9 | 499
preweaning lethality, complete... 8 | 979
decreased vertical activity 7 | 208
increased total body fat amoun... 6 | 134
increased circulating choleste... 5 | 66
abnormal heart morphology 4 | 162
decreased body weight 4 | 161
enlarged heart 4 | 210
increased circulating alkaline... 4 | 122
abnormal behavior 3 | 298
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased bone mineral density 3 | 126
decreased circulating LDL chol... 3 | 38
decreased lymphocyte cell numb... 3 | 83
embryonic lethality prior to t... 3 | 278
increased circulating LDL chol... 3 | 13
increased lean body mass 3 | 172
increased red blood cell distr... 3 | 34
limb grasping 3 | 41
abnormal bone mineralization 2 | 38
abnormal brain morphology 2 | 13
abnormal gait 2 | 69
abnormal retina morphology 2 | 71
decreased bone mineral content 2 | 151
decreased circulating chloride... 2 | 30
decreased circulating creatini... 2 | 39
decreased circulating iron lev... 2 | 32
decreased circulating triglyce... 2 | 79
decreased heart weight 2 | 27
decreased leukocyte cell numbe... 2 | 73
embryonic lethality prior to o... 2 | 239
hydroencephaly 2 | 14
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating bilirubi... 2 | 16
increased circulating phosphat... 2 | 26
increased circulating serum al... 2 | 22
increased heart weight 2 | 62
increased hematocrit 2 | 46
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
thrombocytopenia 2 | 56
abnormal cecum morphology 1 | 7
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal locomotor behavior 1 | 24
abnormal neural tube morpholog... 1 | 12
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
decreased CD4-positive, alpha ... 1 | 7
decreased IgG1 level 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
edema 1 | 59
enlarged uterus 1 | 11
impaired righting response 1 | 26
increased B cell number 1 | 9
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
male infertility 1 | 123
pale yolk sac 1 | 25
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16

Disease

Obesity 133 | 678
Carcinoma 125 | 11,493
psoriasis 118 | 6,694
diabetes mellitus 116 | 1,728
Cancer 106 | 2,499
ovarian cancer 106 | 8,520
osteosarcoma 84 | 7,950
lung cancer 82 | 4,740
invasive ductal carcinoma 81 | 2,951
glioblastoma 76 | 5,792
ductal carcinoma in situ 68 | 1,745
medulloblastoma, large-cell 68 | 6,241
Breast cancer 61 | 3,578
breast carcinoma 61 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 61 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 60 | 3,291
ependymoma 59 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 59 | 2,955
lung adenocarcinoma 59 | 2,716
atypical teratoid / rhabdoid tumor 57 | 5,112
Hyperglycemia 55 | 137
malignant mesothelioma 55 | 3,232
non-small cell lung cancer 52 | 2,890
Hypertension 51 | 396
Astrocytoma, Pilocytic 50 | 3,081
lung carcinoma 49 | 2,843
interstitial cystitis 48 | 2,312
Fatty liver disease 46 | 103
Schizophrenia 46 | 1,160
ulcerative colitis 46 | 1,819
Atherosclerosis 45 | 291
pancreatic cancer 44 | 2,398
pituitary cancer 44 | 1,972
Kidney disease 43 | 430
group 3 medulloblastoma 42 | 4,104
Liver Cirrhosis, Experimental 41 | 769
Polycystic ovary syndrome 41 | 360
Autosomal recessive predisposition 40 | 1,442
Heart disease 40 | 306
tuberculosis 40 | 2,010
adrenocortical carcinoma 39 | 1,428
cystic fibrosis 38 | 1,696
Atopic dermatitis 37 | 952
fibroadenoma 36 | 559
Hyperinsulinism 35 | 133
Lipid metabolism disorder 35 | 114
Rheumatoid arthritis 35 | 1,191
Arthritis 34 | 290
Breast Neoplasms 34 | 445
Mammary Neoplasms 34 | 425
Alzheimer's disease 33 | 658
Coronary artery disease 33 | 268
Hypertensive disease 33 | 292
adult high grade glioma 33 | 3,801
Heart failure 32 | 162
Prostatic Neoplasms 32 | 495
oligodendroglioma 32 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 32 | 1,962
Liver disease 31 | 237
Vascular disease 31 | 319
Carcinoma, Hepatocellular 30 | 228
Liver carcinoma 30 | 240
acute quadriplegic myopathy 30 | 1,158
astrocytic glioma 30 | 2,597
primitive neuroectodermal tumor 29 | 3,035
Bipolar Disorder 28 | 666
Osteoporosis 28 | 363
Cerebrovascular disease 27 | 238
Depressive disorder 27 | 409
Diabetes Mellitus, Experimental 27 | 108
colon cancer 27 | 1,478
autosomal dominant Emery-Dreifuss muscular dystrophy 26 | 510
non primary Sjogren syndrome sicca 26 | 891
Insulin Resistance 25 | 72
Kidney cancer 25 | 2,613
gastric carcinoma 25 | 807
primary pancreatic ductal adenocarcinoma 25 | 1,109
Diabetes Mellitus, Non-Insulin-Dependent 24 | 145
pediatric high grade glioma 24 | 1,064
Asthma 23 | 385
Hypoglycemia 23 | 152
Mental Depression 23 | 333
group 4 medulloblastoma 23 | 1,855
juvenile dermatomyositis 23 | 1,187
subependymal giant cell astrocytoma 23 | 2,287
Anemia 22 | 365
Hypersensitivity reaction type II disease 22 | 253
Lung Neoplasms 22 | 232
Parkinson's disease 22 | 392
Stomach Neoplasms 22 | 300
dermatomyositis 22 | 966
Diabetes Mellitus, Type 2 21 | 142
Duchenne muscular dystrophy 21 | 601
Inflammatory bowel disease 21 | 151
Lung disease 21 | 142
Myocardial Ischemia 21 | 169
Pick disease 21 | 1,894
Seizures 21 | 596
cutaneous lupus erythematosus 21 | 1,057
Multiple Sclerosis 20 | 540

Tissue

Endocrine System 194 | 18,159
Digestive Tract 191 | 17,369
Female tissues 191 | 17,400
Liver and Pancreas 189 | 16,750
Skin and soft tissues 189 | 17,230
Blood and immune system 188 | 16,909
Male tissues 186 | 17,142
Nervous System 186 | 16,725
Urinary Tract 186 | 16,678
Respiratory system 183 | 16,393
Cardiovascular System 179 | 15,192

Target Family

Non-IDG 98 | 12,091
Enzyme 37 | 4,145
Transcription Factor 26 | 1,400
Kinase 16 | 634
GPCR 12 | 408
Nuclear Receptor 4 | 48
Transporter 4 | 473
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Adipocyte 199 | 199
Blood 1,962 | 1,962
Brain 1,516 | 1,516
Immune system 1,205 | 1,205
Muscle 1,170 | 1,170
Liver 1,045 | 1,045
Adult 1,013 | 1,013
Heart 914 | 914
Kidney 888 | 888
Neuron 779 | 779
Skin 763 | 763
Intestine 665 | 665
Lung 663 | 663
Spinal cord 549 | 549
Bone marrow 513 | 513
Breast 450 | 450
Finger 438 | 438
Blood vessel 398 | 398
Hematopoietic stem cell 379 | 379
Artery 356 | 356
Ovary 353 | 353
Ganglion 334 | 334
Retina 330 | 330
Urine 298 | 298
Nerve 290 | 290
Semen 285 | 285
Mesenchyme 275 | 275
Fiber 274 | 274
Germ cell 264 | 264
BTO:0000964 256 | 256
Pancreas 250 | 250
Breast cancer cell line 246 | 246
Breast cancer cell 235 | 235
Trophoblast 228 | 228
Embryonic stem cell 226 | 226
Adrenal gland 212 | 212
Lymph node 198 | 198
Thyroid gland 196 | 196
Stromal cell 195 | 195
Cornea 194 | 194
Stomach 185 | 185
Osteoblast 180 | 180
Marrow 169 | 169
Mesenchymal stem cell 167 | 167
Blood plasma 163 | 163
T-lymphocyte 161 | 161
Mast cell 159 | 159
Peripheral nerve 157 | 157
Cranium 149 | 149
Filament 144 | 144
Ectoderm 143 | 143
Root nodule 140 | 140
Spermatid 138 | 138
Neural crest 134 | 134
Blood vessel endothelium 133 | 133
Uterine cervix 132 | 132
Prostate cancer cell line 129 | 129
Spleen 129 | 129
HeLa cell 128 | 128
Hepatoma cell 126 | 126
Vasculature 123 | 123
Neural tube 122 | 122
Prostate gland cancer cell 121 | 121
Knee 120 | 120
Lung cancer cell 119 | 119
Seedling 119 | 119
Neural stem cell 117 | 117
HUVEC cell 115 | 115
Blastocyst 114 | 114
Fruit 113 | 113
Tendon 111 | 111
Bronchoalveolar lavage 108 | 108
Hip 108 | 108
NIH-3T3 cell 106 | 106
Myotube 105 | 105
Capillary 104 | 104
Salivary gland 104 | 104
Primordium 102 | 102
Somatic cell 102 | 102
Colonic cancer cell 101 | 101
Myoblast 101 | 101
Germ 99 | 99
B-lymphocyte 98 | 98
Vegetative cell 98 | 98
Bud 96 | 96
Peripheral blood 96 | 96
Endoderm 93 | 93
Hair cell 93 | 93
Vagina 93 | 93
Epididymis 92 | 92
Neonate 92 | 92
Spike 92 | 92
3T3-L1 cell 91 | 91
dr9 90 | 90
Ascites 88 | 88
Embryonic fibroblast 88 | 88
Parenchyma 88 | 88
Saliva 87 | 87
Synovial tissue 86 | 86
Cancer stem cell 84 | 84

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GDH/6PGL endoplasmic bifunctional protein H6PD Tbio Non-IDG -2.24806 169.7 207
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Glycerol kinase 3 GK3P Tdark Kinase -1.84692 109.0 0
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075