Development Level

Tbio 99 | 10,625
Tchem 67 | 1,890
Tclin 23 | 602
Tdark 5 | 7,003

Collection

Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

decreased body weight 5 | 174
increased circulating choleste... 5 | 53
increased circulating alkaline... 4 | 119
preweaning lethality, complete... 4 | 633
preweaning lethality, incomple... 4 | 260
decreased bone mineral density 3 | 126
decreased circulating LDL chol... 3 | 37
decreased circulating chloride... 3 | 32
increased circulating HDL chol... 3 | 63
increased circulating LDL chol... 3 | 15
increased mean corpuscular hem... 3 | 93
abnormal bone mineralization 2 | 55
abnormal gait 2 | 51
abnormal heart morphology 2 | 51
abnormal lens morphology 2 | 73
abnormal maxilla morphology 2 | 16
abnormal respiratory quotient 2 | 9
abnormal retina morphology 2 | 100
abnormal tooth morphology 2 | 24
cataract 2 | 26
decreased caudal vertebrae num... 2 | 49
decreased circulating creatini... 2 | 31
decreased circulating iron lev... 2 | 25
decreased granulocyte number 2 | 8
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
decreased monocyte cell number 2 | 28
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
increased B cell number 2 | 23
increased circulating phosphat... 2 | 24
increased circulating potassiu... 2 | 31
increased circulating serum al... 2 | 25
increased erythrocyte cell num... 2 | 26
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
increased total body fat amoun... 2 | 57
limb grasping 2 | 35
thrombocytopenia 2 | 46
abnormal brain morphology 1 | 6
abnormal embryo size 1 | 112
abnormal glucose homeostasis 1 | 5
abnormal head morphology 1 | 10
abnormal iris morphology 1 | 12
abnormal neural tube morpholog... 1 | 8
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal startle reflex 1 | 14
absent optic nerve 1 | 1
decreased CD4-positive, alpha ... 1 | 19
decreased IgG1 level 1 | 4
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased circulating calcium ... 1 | 33
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased effector memory CD8-... 1 | 24
decreased gamma-delta T cell n... 1 | 18
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
embryonic lethality prior to o... 1 | 148
hydroencephaly 1 | 6
hypoactivity 1 | 89
increased T cell number 1 | 15
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating amylase ... 1 | 13
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 25
increased red blood cell distr... 1 | 21
increased vertical activity 1 | 18
irregularly shaped pupil 1 | 7
lethargy 1 | 5
narrow eye opening 1 | 15
pale yolk sac 1 | 12
small seminal vesicle 1 | 6
straub tail 1 | 26
thrombocytosis 1 | 23
tremors 1 | 34

Disease

Obesity 125 | 616
psoriasis 117 | 6,685
diabetes mellitus 111 | 1,663
Cancer 103 | 2,346
ovarian cancer 102 | 8,484
osteosarcoma 83 | 7,933
invasive ductal carcinoma 78 | 2,950
lung cancer 75 | 4,466
glioblastoma 70 | 5,572
Metabolic syndrome X 66 | 155
ductal carcinoma in situ 65 | 1,745
medulloblastoma, large-cell 65 | 6,234
intraductal papillary-mucinous carcinoma (IPMC) 59 | 2,988
lung adenocarcinoma 58 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 57 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 57 | 3,289
breast carcinoma 56 | 1,614
ulcerative colitis 54 | 2,087
malignant mesothelioma 52 | 3,162
Breast cancer 51 | 3,094
Hyperglycemia 50 | 120
lung carcinoma 49 | 2,844
pilocytic astrocytoma 49 | 3,086
atypical teratoid / rhabdoid tumor 47 | 4,369
non-small cell lung cancer 47 | 2,798
interstitial cystitis 45 | 2,299
pancreatic cancer 44 | 2,300
Atherosclerosis 43 | 275
Fatty liver disease 42 | 84
pituitary cancer 42 | 1,972
Heart disease 41 | 279
Kidney disease 41 | 396
Hypertension 39 | 287
cystic fibrosis 39 | 1,665
pediatric high grade glioma 38 | 2,712
Atopic dermatitis 37 | 944
adrenocortical carcinoma 37 | 1,427
group 4 medulloblastoma 36 | 1,875
fibroadenoma 35 | 557
tuberculosis 35 | 1,557
Lipid metabolism disorder 33 | 102
Rheumatoid Arthritis 33 | 1,160
Arthritis 32 | 248
Coronary artery disease 32 | 240
Mammary Neoplasms 32 | 410
Liver disease 31 | 219
Polycystic Ovary Syndrome 31 | 332
ependymoma 31 | 2,514
oligodendroglioma 31 | 2,849
Alzheimer's disease 30 | 644
Prostatic Neoplasms 30 | 471
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,795
Hyperinsulinism 29 | 63
Liver carcinoma 29 | 217
acute quadriplegic myopathy 29 | 1,157
Hypertensive disease 28 | 193
primary pancreatic ductal adenocarcinoma 28 | 1,271
primitive neuroectodermal tumor 28 | 3,031
Osteoporosis 27 | 257
Vascular disease 27 | 281
colon cancer 27 | 1,475
gastric carcinoma 27 | 832
Diabetes Mellitus, Experimental 26 | 106
astrocytoma 26 | 1,493
Cerebrovascular disease 25 | 231
Carcinoma 24 | 2,147
Diabetes Mellitus, Non-Insulin-Dependent 24 | 157
autosomal dominant Emery-Dreifuss muscular dystrophy 24 | 499
non primary Sjogren syndrome sicca 24 | 840
posterior fossa group A ependymoma 24 | 1,511
astrocytic glioma 23 | 2,241
Lung Neoplasms 22 | 171
dermatomyositis 22 | 933
juvenile dermatomyositis 22 | 1,189
subependymal giant cell astrocytoma 22 | 2,287
Asthma 21 | 349
Inflammatory bowel disease 21 | 142
Multiple Sclerosis 21 | 498
Myocardial Ischemia 21 | 169
Pick disease 21 | 1,893
cutaneous lupus erythematosus 21 | 1,056
Duchenne muscular dystrophy 20 | 602
Heart failure 20 | 80
Hypersensitivity reaction type II disease 20 | 235
Lung disease 20 | 132
Stomach Neoplasms 20 | 282
Parkinson's disease 19 | 364
adult high grade glioma 19 | 2,148
Anemia 18 | 252
Inflammation 18 | 109
Mammary Neoplasms, Experimental 18 | 150
Schizophrenia 18 | 501
esophageal adenocarcinoma 18 | 737
Adenoma 17 | 165
Endometriosis 17 | 535
Hypoglycemia 17 | 81
Myopathy 17 | 128
Reperfusion Injury 17 | 84
posterior fossa group B ependymoma 17 | 1,530
Peripheral Neuropathy 16 | 303

Tissue

Digestive Tract 190 | 18,473
Female tissues 190 | 18,647
Blood and immune system 189 | 17,995
Endocrine System 189 | 18,512
Liver and Pancreas 189 | 18,136
Nervous System 188 | 18,561
Skin and soft tissues 188 | 18,115
Urinary Tract 188 | 18,444
Male tissues 186 | 17,969
Cardiovascular System 185 | 17,958
Respiratory system 183 | 17,484

Target Family

Non-IDG 98 | 11,971
Enzyme 36 | 4,146
Transcription Factor 23 | 1,400
Kinase 16 | 634
GPCR 11 | 406
Nuclear Receptor 4 | 48
Transporter 4 | 473
Epigenetic 1 | 242
TF/Epigenetic 1 | 38

Jensen-TM Tissue

Adipocyte 194 | 194
Blood 1,867 | 1,867
Brain 1,442 | 1,442
Immune system 1,150 | 1,150
Muscle 1,110 | 1,110
Liver 1,001 | 1,001
Adult 976 | 976
Heart 881 | 881
Kidney 840 | 840
Neuron 744 | 744
Skin 735 | 735
Intestine 626 | 626
Lung 623 | 623
Spinal cord 526 | 526
Bone marrow 494 | 494
Finger 432 | 432
Breast 429 | 429
Blood vessel 387 | 387
Hematopoietic stem cell 370 | 370
Ovary 342 | 342
Artery 327 | 327
Ganglion 322 | 322
Retina 301 | 301
Nerve 290 | 290
Urine 281 | 281
Semen 266 | 266
Fiber 263 | 263
Mesenchyme 261 | 261
Germ cell 244 | 244
BTO:0000964 243 | 243
Pancreas 239 | 239
Breast cancer cell line 228 | 228
Trophoblast 225 | 225
Breast cancer cell 222 | 222
Embryonic stem cell 218 | 218
Adrenal gland 207 | 207
Lymph node 206 | 206
Thyroid gland 190 | 190
Cornea 186 | 186
Stromal cell 183 | 183
Stomach 179 | 179
Osteoblast 175 | 175
Marrow 169 | 169
Blood plasma 165 | 165
Mesenchymal stem cell 159 | 159
T-lymphocyte 158 | 158
Mast cell 155 | 155
Peripheral nerve 155 | 155
Cranium 141 | 141
Ectoderm 141 | 141
Filament 139 | 139
Root nodule 135 | 135
Spermatid 135 | 135
Neural crest 134 | 134
Spleen 130 | 130
Uterine cervix 124 | 124
Blood vessel endothelium 122 | 122
Prostate cancer cell line 121 | 121
Prostate gland cancer cell 121 | 121
HeLa cell 120 | 120
Neural tube 120 | 120
Vasculature 119 | 119
Blastocyst 117 | 117
HUVEC cell 116 | 116
Hepatoma cell 113 | 113
Fruit 112 | 112
Knee 112 | 112
Neural stem cell 112 | 112
NIH-3T3 cell 109 | 109
Seedling 109 | 109
Tendon 108 | 108
Lung cancer cell 107 | 107
Hip 106 | 106
Bronchoalveolar lavage 105 | 105
Primordium 104 | 104
Bud 103 | 103
Capillary 101 | 101
Myotube 101 | 101
B-lymphocyte 99 | 99
Myoblast 99 | 99
Colonic cancer cell 98 | 98
Peripheral blood 96 | 96
Vegetative cell 96 | 96
Germ 95 | 95
Somatic cell 92 | 92
Endoderm 91 | 91
Embryonic fibroblast 90 | 90
Salivary gland 90 | 90
3T3-L1 cell 88 | 88
Epididymis 88 | 88
Neonate 88 | 88
Mesoderm 87 | 87
Vagina 87 | 87
Hair cell 86 | 86
Ascites 85 | 85
Parenchyma 85 | 85
Saliva 84 | 84
Synovial tissue 83 | 83
Carcass 82 | 82
Spike 80 | 80

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Glypican-3 GPC3 Tbio Non-IDG -2.85848 794.8 523
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474
Zinc-alpha-2-glycoprotein AZGP1 Tbio Non-IDG -2.14317 164.1 198
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
Fatty acid synthase FASN Tchem Enzyme -2.49948 348.5 388
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549