Development Level

Tbio 945 | 10,625
Tdark 341 | 7,003
Tchem 155 | 1,890
Tclin 31 | 602

Collection

Eligible Kinase Proteins 7 | 134
Eligible Ion Channel Proteins 6 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 88 | 633
embryonic lethality prior to t... 26 | 187
preweaning lethality, incomple... 23 | 260
decreased total body fat amoun... 19 | 186
abnormal behavior 17 | 226
embryonic lethality prior to o... 17 | 148
decreased body weight 16 | 174
decreased lean body mass 16 | 195
abnormal embryo size 13 | 112
abnormal retina morphology 13 | 100
decreased bone mineral content 13 | 157
prenatal lethality prior to he... 13 | 64
increased bone mineral content 12 | 92
increased lean body mass 11 | 107
increased mean corpuscular vol... 11 | 91
abnormal coat/hair pigmentatio... 10 | 54
decreased body length 10 | 108
decreased bone mineral density 10 | 126
increased startle reflex 10 | 38
male infertility 10 | 62
abnormal bone structure 9 | 131
abnormal kidney morphology 9 | 30
decreased circulating glucose ... 9 | 121
decreased rib number 9 | 59
enlarged heart 9 | 111
increased circulating alkaline... 9 | 119
increased grip strength 9 | 83
abnormal retinal pigmentation 8 | 61
hypoactivity 8 | 89
short tibia 8 | 82
decreased circulating serum al... 7 | 79
decreased circulating triglyce... 7 | 83
decreased grip strength 7 | 123
decreased prepulse inhibition 7 | 52
increased fasted circulating g... 7 | 68
small testis 7 | 37
abnormal lens morphology 6 | 73
abnormal seminal vesicle morph... 6 | 47
decreased caudal vertebrae num... 6 | 49
decreased circulating insulin ... 6 | 75
embryonic growth retardation 6 | 28
hyperactivity 6 | 108
increased body weight 6 | 42
increased circulating chloride... 6 | 43
increased exploration in new e... 6 | 56
increased or absent threshold ... 6 | 128
abnormal heart morphology 5 | 51
abnormal neural tube closure 5 | 37
abnormal testis morphology 5 | 30
decreased circulating alanine ... 5 | 53
decreased lumbar vertebrae num... 5 | 62
decreased startle reflex 5 | 48
decreased threshold for audito... 5 | 32
increased circulating sodium l... 5 | 71
increased mean corpuscular hem... 5 | 93
increased monocyte cell number 5 | 27
increased rib number 5 | 41
increased sacral vertebrae num... 5 | 62
abnormal limb bud morphology 4 | 15
abnormal tail morphology 4 | 17
cardiovascular system phenotyp... 4 | 35
decreased CD4-positive, CD25-p... 4 | 24
decreased CD8-positive, alpha-... 4 | 26
decreased circulating aspartat... 4 | 27
decreased circulating chloride... 4 | 32
decreased circulating free fat... 4 | 39
decreased circulating fructosa... 4 | 31
decreased circulating potassiu... 4 | 17
decreased circulating sodium l... 4 | 18
decreased eosinophil cell numb... 4 | 41
decreased hemoglobin content 4 | 53
decreased leukocyte cell numbe... 4 | 54
decreased mean corpuscular vol... 4 | 50
enlarged lymph nodes 4 | 27
hydrops fetalis 4 | 22
increased B cell number 4 | 23
increased CD4-positive, alpha ... 4 | 15
increased bone mineral density 4 | 52
increased circulating triglyce... 4 | 24
increased gamma-delta T cell n... 4 | 16
increased leukocyte cell numbe... 4 | 37
thrombocytopenia 4 | 46
tremors 4 | 34
abnormal behavioral response t... 3 | 52
abnormal coat appearance 3 | 25
abnormal epididymis morphology 3 | 31
abnormal lung morphology 3 | 15
abnormal sleep behavior 3 | 63
abnormal vertebrae morphology 3 | 14
abnormal vibrissa morphology 3 | 17
anophthalmia 3 | 20
decreased T cell number 3 | 31
decreased circulating bilirubi... 3 | 14
decreased circulating glycerol... 3 | 19
decreased fasted circulating g... 3 | 49
decreased vertical activity 3 | 22
impaired glucose tolerance 3 | 52
increased circulating iron lev... 3 | 25
increased prepulse inhibition 3 | 21
increased total body fat amoun... 3 | 57

Disease

ovarian cancer 890 | 8,484
osteosarcoma 732 | 7,933
psoriasis 556 | 6,685
medulloblastoma, large-cell 543 | 6,234
glioblastoma 506 | 5,572
lung cancer 453 | 4,466
atypical teratoid / rhabdoid tumor 373 | 4,369
malignant mesothelioma 336 | 3,162
intraductal papillary-mucinous neoplasm (IPMN) 307 | 3,289
Breast cancer 297 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 283 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 273 | 2,956
invasive ductal carcinoma 266 | 2,950
primitive neuroectodermal tumor 260 | 3,031
lung adenocarcinoma 244 | 2,713
pediatric high grade glioma 241 | 2,712
ependymoma 236 | 2,514
non-small cell lung cancer 236 | 2,798
oligodendroglioma 234 | 2,849
pilocytic astrocytoma 224 | 3,086
pancreatic cancer 221 | 2,300
group 3 medulloblastoma 203 | 2,254
lung carcinoma 203 | 2,844
Cancer 196 | 2,346
subependymal giant cell astrocytoma 195 | 2,287
astrocytic glioma 192 | 2,241
Pick disease 182 | 1,893
group 4 medulloblastoma 177 | 1,875
Multiple myeloma 169 | 1,327
breast carcinoma 167 | 1,614
pancreatic ductal adenocarcinoma liver metastasis 165 | 1,795
adult high grade glioma 162 | 2,148
ulcerative colitis 160 | 2,087
astrocytoma 155 | 1,493
interstitial cystitis 151 | 2,299
pituitary cancer 151 | 1,972
primary pancreatic ductal adenocarcinoma 151 | 1,271
Carcinoma 150 | 2,147
sonic hedgehog group medulloblastoma 148 | 1,482
colon cancer 142 | 1,475
tuberculosis 137 | 1,557
adrenocortical carcinoma 135 | 1,427
ductal carcinoma in situ 135 | 1,745
cystic fibrosis 134 | 1,665
juvenile dermatomyositis 133 | 1,189
dermatomyositis 127 | 933
acute quadriplegic myopathy 126 | 1,157
diabetes mellitus 126 | 1,663
posterior fossa group A ependymoma 121 | 1,511
medulloblastoma 120 | 1,524
posterior fossa group B ependymoma 111 | 1,530
spina bifida 99 | 1,064
Rheumatoid Arthritis 96 | 1,160
atypical teratoid/rhabdoid tumor 93 | 1,095
Waldenstrons macroglobulinemia 87 | 765
active Crohn's disease 80 | 918
acute myeloid leukemia 80 | 780
tuberculosis and treatment for 6 months 79 | 686
non primary Sjogren syndrome sicca 76 | 840
Duchenne muscular dystrophy 72 | 602
hepatocellular carcinoma 72 | 532
nasopharyngeal carcinoma 70 | 1,056
Atopic dermatitis 69 | 944
primary Sjogren syndrome 69 | 789
progressive supranuclear palsy 65 | 674
gastric carcinoma 64 | 832
cutaneous lupus erythematosus 63 | 1,056
aldosterone-producing adenoma 60 | 664
esophageal adenocarcinoma 56 | 737
pancreatic carcinoma 56 | 567
autosomal dominant Emery-Dreifuss muscular dystrophy 54 | 499
fibroadenoma 53 | 557
gastric cancer 53 | 430
Down syndrome 49 | 548
Intellectual disability 49 | 573
Alzheimer's disease 48 | 644
Endometriosis 46 | 535
Prostatic Neoplasms 41 | 471
Mammary Neoplasms 40 | 410
glioblastoma multiforme 40 | 347
inflammatory breast cancer 40 | 404
Obesity 39 | 616
chronic rhinosinusitis 39 | 512
hereditary spastic paraplegia 39 | 313
Amyotrophic Lateral Sclerosis 38 | 431
Neurodegenerative disease 37 | 383
Multiple Sclerosis 34 | 498
Schizophrenia 34 | 501
IGA Glomerulonephritis 33 | 454
mucosa-associated lymphoid tissue lymphoma 31 | 480
non-small cell lung carcinoma 30 | 413
sarcoidosis 30 | 358
interstitial lung disease 26 | 291
Parkinson's disease 25 | 364
Acquired metabolic disease 24 | 267
Chronic Lymphocytic Leukemia 24 | 242
tuberculosis and treatment for 3 months 24 | 327
urothelial carcinoma 24 | 318
Kidney disease 23 | 396
Polycystic Ovary Syndrome 23 | 332

Tissue

Nervous System 1,453 | 18,561
Female tissues 1,451 | 18,647
Blood and immune system 1,449 | 17,995
Digestive Tract 1,449 | 18,473
Liver and Pancreas 1,449 | 18,136
Male tissues 1,448 | 17,969
Endocrine System 1,447 | 18,512
Cardiovascular System 1,444 | 17,958
Urinary Tract 1,444 | 18,444
Skin and soft tissues 1,440 | 18,115
Respiratory system 1,436 | 17,484

Target Family

Non-IDG 872 | 11,971
Enzyme 336 | 4,146
Transcription Factor 126 | 1,400
Kinase 50 | 634
Epigenetic 35 | 242
Transporter 18 | 473
Ion Channel 14 | 341
GPCR 11 | 406
Nuclear Receptor 5 | 48
TF/Epigenetic 4 | 38
oGPCR 1 | 421

Jensen-KB Tissue

Uterus 1,472 | 1,472
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinaldehyde-binding protein 1 RLBP1 Tbio Non-IDG -2.12314 137.8 95
Interferon regulatory factor 2-binding protein 1 IRF2BP1 Tdark Non-IDG -0.29200 1.63 121
Sex comb on midleg-like protein 2 SCML2 Tbio Epigenetic -1.13986 13.7 93
mRNA decay activator protein ZFP36 ZFP36 Tbio Non-IDG -2.38153 220.3 0
Ubiquitin carboxyl-terminal hydrolase 22 USP22 Tbio Enzyme -1.59877 51.0 199
NHL repeat-containing protein 2 NHLRC2 Tdark Non-IDG 0.78 1.17 50
Equilibrative nucleoside transporter 3 SLC29A3 Tbio Transporter -2.36515 247.3 58
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial PGS1 Tdark Enzyme -0.35218 2.20 100
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
Nucleolar GTP-binding protein 1 GTPBP4 Tbio Non-IDG -3.21425 1443.3 95