Development Level

Tbio 79 | 11,445
Tdark 29 | 6,588
Tchem 11 | 1,598
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavior 4 | 298
decreased lean body mass 4 | 135
hyperactivity 4 | 148
preweaning lethality, incomple... 4 | 499
decreased total body fat amoun... 3 | 207
hypoactivity 3 | 132
increased total body fat amoun... 3 | 134
abnormal behavioral response t... 2 | 66
abnormal heart morphology 2 | 162
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased circulating choleste... 2 | 93
decreased grip strength 2 | 116
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular vol... 2 | 79
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
enlarged spleen 2 | 41
increased body length 2 | 32
increased circulating alkaline... 2 | 122
increased heart weight 2 | 62
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal spleen morphology 1 | 55
absent adrenal gland 1 | 2
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased basophil cell number 1 | 7
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased coping response 1 | 4
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
limb grasping 1 | 41
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
thin ventricular wall 1 | 24

Disease

Carcinoma 96 | 11,493
osteosarcoma 71 | 7,950
ovarian cancer 71 | 8,520
glioblastoma 54 | 5,792
medulloblastoma, large-cell 53 | 6,241
atypical teratoid / rhabdoid tumor 49 | 5,112
lung cancer 42 | 4,740
adult high grade glioma 39 | 3,801
psoriasis 39 | 6,694
ependymoma 36 | 4,679
group 3 medulloblastoma 33 | 4,104
Breast cancer 32 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
Kidney cancer 31 | 2,613
Astrocytoma, Pilocytic 29 | 3,081
astrocytic glioma 29 | 2,597
primitive neuroectodermal tumor 28 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
invasive ductal carcinoma 26 | 2,951
pancreatic cancer 26 | 2,398
malignant mesothelioma 25 | 3,232
oligodendroglioma 24 | 2,850
Cancer 23 | 2,499
lung carcinoma 23 | 2,843
juvenile dermatomyositis 22 | 1,187
ulcerative colitis 21 | 1,819
subependymal giant cell astrocytoma 19 | 2,287
group 4 medulloblastoma 18 | 1,855
primary pancreatic ductal adenocarcinoma 18 | 1,109
Pick disease 17 | 1,894
breast carcinoma 16 | 1,638
interstitial cystitis 16 | 2,312
tuberculosis 16 | 2,010
adrenocortical carcinoma 15 | 1,428
diabetes mellitus 14 | 1,728
non-small cell lung cancer 14 | 2,890
pituitary cancer 14 | 1,972
cystic fibrosis 13 | 1,696
dermatomyositis 13 | 966
gastric carcinoma 13 | 807
lung adenocarcinoma 13 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
acute quadriplegic myopathy 12 | 1,158
Autosomal recessive predisposition 11 | 1,442
Rheumatoid arthritis 11 | 1,191
astrocytoma 11 | 1,146
colon cancer 11 | 1,478
ductal carcinoma in situ 11 | 1,745
spina bifida 11 | 1,074
Duchenne muscular dystrophy 10 | 601
sarcoidosis 10 | 370
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
medulloblastoma 9 | 720
Atopic dermatitis 8 | 952
Breast Neoplasms 8 | 445
Intellectual disability 8 | 1,016
Liver Cirrhosis, Experimental 8 | 769
Multiple Sclerosis 8 | 540
Neurodegenerative disease 8 | 414
Schizophrenia 8 | 1,160
active Crohn's disease 8 | 922
gastric cancer 8 | 459
nasopharyngeal carcinoma 8 | 1,058
Endometriosis 7 | 540
Mammary Neoplasms 7 | 425
Multiple myeloma 7 | 1,332
Systemic lupus erythematosus 7 | 194
pediatric high grade glioma 7 | 1,064
primary Sjogren syndrome 7 | 735
Alzheimer's disease 6 | 658
Down syndrome 6 | 499
Liver cancer 6 | 604
Osteoporosis 6 | 363
cutaneous lupus erythematosus 6 | 1,057
pancreatic carcinoma 6 | 562
Acquired scoliosis 5 | 281
Amyotrophic lateral sclerosis 5 | 451
Congenital pes cavus 5 | 88
Curvature of spine 5 | 282
Distal amyotrophy 5 | 51
Epilepsy 5 | 792
Prostatic Neoplasms 5 | 495
active ulcerative colitis 5 | 764
aldosterone-producing adenoma 5 | 665
hereditary spastic paraplegia 5 | 318
progressive supranuclear palsy 5 | 676
sonic hedgehog group medulloblastoma 5 | 467
tuberculosis and treatment for 6 months 5 | 409
Becker muscular dystrophy 4 | 191
Bipolar Disorder 4 | 666
Chronic obstructive pulmonary disease 4 | 184
Mental Depression 4 | 333
Polycystic ovary syndrome 4 | 360
Seizures 4 | 596
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 783
hepatocellular carcinoma 4 | 547
limb girdle muscular dystrophy 2A 4 | 213
non diabetic and post-ischemic heart failure 4 | 200

Tissue

Digestive Tract 121 | 17,369
Endocrine System 121 | 18,159
Female tissues 121 | 17,400
Liver and Pancreas 121 | 16,750
Male tissues 121 | 17,142
Skin and soft tissues 121 | 17,230
Nervous System 120 | 16,725
Respiratory system 120 | 16,393
Blood and immune system 119 | 16,909
Urinary Tract 119 | 16,678
Cardiovascular System 118 | 15,192

Target Family

Non-IDG 71 | 12,091
Enzyme 28 | 4,145
Transcription Factor 13 | 1,400
Epigenetic 2 | 242
GPCR 2 | 408
Kinase 2 | 634
Nuclear Receptor 2 | 48
Transporter 2 | 473

Jensen-KB Tissue

Uterine endometrium 122 | 122
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase RNF216 RNF216 Tbio Enzyme -1.27012 17.8 170
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Protein misato homolog 1 MSTO1 Tbio Non-IDG -1.77593 58.1 65
Condensin-2 complex subunit G2 NCAPG2 Tbio Non-IDG -0.75957 5.48 110
DNA annealing helicase and endonuclease ZRANB3 ZRANB3 Tbio Enzyme -2.18014 154.3 36
Ketimine reductase mu-crystallin CRYM Tbio Enzyme -1.70644 52.5 199
O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS Tbio Enzyme -2.11362 120.5 120
Transmembrane protein 170A TMEM170A Tdark Non-IDG 0.00000 1.18 3
Leucine-rich repeat transmembrane neuronal protein 3 LRRTM3 Tbio Non-IDG -0.66354 6.01 60
Lysophospholipid acyltransferase 5 LPCAT3 Tbio Enzyme -2.21771 162.8 32