Development Level

Tbio 34 | 11,651
Tdark 13 | 6,593
Tchem 2 | 1,388

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
anophthalmia 1 | 33
decreased B cell number 1 | 5
decreased IgG1 level 1 | 8
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hydrometra 1 | 53
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased startle reflex 1 | 112
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
scaly skin 1 | 4
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
thick ventricular wall 1 | 7
thrombocytopenia 1 | 56

Disease

Carcinoma 36 | 11,493
ovarian cancer 31 | 8,520
osteosarcoma 25 | 7,950
medulloblastoma, large-cell 24 | 6,241
glioblastoma 21 | 5,792
atypical teratoid / rhabdoid tumor 17 | 5,112
ependymoma 17 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
psoriasis 15 | 6,694
lung cancer 14 | 4,740
non-small cell lung cancer 14 | 2,890
pancreatic cancer 14 | 2,398
Breast cancer 12 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
Cancer 11 | 2,499
adult high grade glioma 11 | 3,801
Astrocytoma, Pilocytic 9 | 3,081
Pick disease 9 | 1,894
adrenocortical carcinoma 9 | 1,428
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
malignant mesothelioma 9 | 3,232
oligodendroglioma 9 | 2,850
Kidney cancer 8 | 2,613
group 3 medulloblastoma 8 | 4,104
Intellectual disability 7 | 1,016
astrocytic glioma 7 | 2,597
hepatocellular carcinoma 7 | 547
juvenile dermatomyositis 7 | 1,187
nasopharyngeal carcinoma 7 | 1,058
pancreatic carcinoma 7 | 562
primitive neuroectodermal tumor 7 | 3,035
lung adenocarcinoma 6 | 2,716
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Adenoma 5 | 167
Atopic dermatitis 5 | 952
Autosomal recessive predisposition 5 | 1,442
Dull intelligence 5 | 645
Familial adenomatous polyposis 5 | 32
Low intelligence 5 | 645
Lynch syndrome 5 | 35
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Rheumatoid arthritis 5 | 1,191
Sebaceous adenoma 5 | 26
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
gastric cancer 5 | 459
group 4 medulloblastoma 5 | 1,855
lung carcinoma 5 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Epilepsy 4 | 792
Liver Cirrhosis, Experimental 4 | 769
Multiple myeloma 4 | 1,332
Seizures 4 | 596
astrocytoma 4 | 1,146
breast carcinoma 4 | 1,638
invasive ductal carcinoma 4 | 2,951
pediatric high grade glioma 4 | 1,064
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109
progressive supranuclear palsy 4 | 676
spina bifida 4 | 1,074
tuberculosis and treatment for 6 months 4 | 409
Breast Neoplasms 3 | 445
Cognitive delay 3 | 608
Endometriosis 3 | 540
Global developmental delay 3 | 608
Mammary Neoplasms 3 | 425
Mental and motor retardation 3 | 608
Parkinson's disease 3 | 392
Schizophrenia 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
interstitial cystitis 3 | 2,312
medulloblastoma 3 | 720
sonic hedgehog group medulloblastoma 3 | 467
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis and treatment for 3 months 3 | 179
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Duchenne muscular dystrophy 2 | 601
Leukemia 2 | 104
Multiple Sclerosis 2 | 540
Polycystic ovary syndrome 2 | 360
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
dermatomyositis 2 | 966
primary Sjogren syndrome 2 | 735
urothelial carcinoma 2 | 318

Tissue

Endocrine System 44 | 18,159
Female tissues 44 | 17,400
Skin and soft tissues 44 | 17,230
Blood and immune system 43 | 16,909
Digestive Tract 43 | 17,369
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Respiratory system 43 | 16,393
Urinary Tract 43 | 16,678
Cardiovascular System 42 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 15 | 4,145
Transcription Factor 4 | 1,400
Transporter 3 | 473
Epigenetic 1 | 242

Jensen-KB Tissue

Uterine endometrial cancer cel... 49 | 49
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase RNF114 RNF114 Tbio Enzyme -1.03564 12.8 142
Probable tRNA pseudouridine synthase 1 TRUB1 Tbio Enzyme -0.96379 8.38 91
WAS/WASL-interacting protein family member 1 WIPF1 Tbio Non-IDG -2.03820 107.4 108
Histone lysine demethylase PHF8 PHF8 Tchem Epigenetic -1.50422 40.0 77
Beta-actin-like protein 2 ACTBL2 Tbio Non-IDG -0.75651 5.61 47
Nucleoporin p54 NUP54 Tbio Non-IDG -0.79147 5.89 76
WD repeat-containing protein 44 WDR44 Tdark Non-IDG -0.46177 3.31 26
TCDD-inducible poly [ADP-ribose] polymerase TIPARP Tbio Enzyme -2.47339 285.2 57
Nuclear envelope integral membrane protein 1 NEMP1 Tdark Non-IDG -0.09691 1.96 20
Zinc finger protein 550 ZNF550 Tdark Transcription Factor 0.00000 102