Development Level

Tbio 295 | 11,445
Tdark 86 | 6,588
Tchem 34 | 1,598
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 37 | 979
embryonic lethality prior to t... 13 | 278
embryonic lethality prior to o... 12 | 239
abnormal behavior 11 | 298
increased lean body mass 10 | 172
abnormal embryo size 8 | 220
preweaning lethality, incomple... 8 | 499
decreased circulating glucose ... 7 | 126
decreased body weight 6 | 161
decreased total body fat amoun... 6 | 207
enlarged heart 6 | 210
male infertility 6 | 123
short tibia 6 | 97
decreased bone mineral content 4 | 151
decreased bone mineral density 4 | 126
decreased circulating triglyce... 4 | 79
decreased lean body mass 4 | 135
decreased vertical activity 4 | 208
embryonic growth retardation 4 | 106
enlarged spleen 4 | 41
hyperactivity 4 | 148
hypoactivity 4 | 132
increased circulating alkaline... 4 | 122
increased mean corpuscular hem... 4 | 36
abnormal behavioral response t... 3 | 66
abnormal bone structure 3 | 187
abnormal heart morphology 3 | 162
abnormal retina morphology 3 | 71
cataract 3 | 92
decreased body length 3 | 101
decreased circulating choleste... 3 | 93
decreased mean corpuscular vol... 3 | 79
female infertility 3 | 60
increased grip strength 3 | 41
increased mean corpuscular hem... 3 | 96
increased mean corpuscular vol... 3 | 92
increased prepulse inhibition 3 | 32
increased startle reflex 3 | 112
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal embryo turning 2 | 31
abnormal kidney morphology 2 | 65
abnormal liver morphology 2 | 17
abnormal rib morphology 2 | 10
abnormal sleep behavior 2 | 70
corneal opacity 2 | 32
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating aspartat... 2 | 34
decreased circulating iron lev... 2 | 32
decreased circulating potassiu... 2 | 20
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular hem... 2 | 50
decreased red blood cell distr... 2 | 41
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating free fat... 2 | 20
increased circulating glucose ... 2 | 24
increased circulating total pr... 2 | 28
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
increased red blood cell distr... 2 | 34
increased total body fat amoun... 2 | 134
pale yolk sac 2 | 25
pallor 2 | 34
small testis 2 | 58
thrombocytopenia 2 | 56
vertebral transformation 2 | 12
abnormal cornea morphology 1 | 31
abnormal epididymis morphology 1 | 42
abnormal heart looping 1 | 5
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal spleen morphology 1 | 55
decreased circulating bilirubi... 1 | 19
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
long tibia 1 | 25
small thymus 1 | 16
vertebral fusion 1 | 23

Disease

ovarian cancer 250 | 8,520
Carcinoma 242 | 11,493
osteosarcoma 206 | 7,950
psoriasis 146 | 6,694
glioblastoma 143 | 5,792
medulloblastoma, large-cell 140 | 6,241
lung cancer 136 | 4,740
atypical teratoid / rhabdoid tumor 124 | 5,112
ependymoma 103 | 4,679
Breast cancer 100 | 3,578
group 3 medulloblastoma 96 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 92 | 3,291
astrocytic glioma 80 | 2,597
malignant mesothelioma 78 | 3,232
adult high grade glioma 77 | 3,801
non-small cell lung cancer 76 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 74 | 2,989
oligodendroglioma 71 | 2,850
lung adenocarcinoma 69 | 2,716
invasive ductal carcinoma 68 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 66 | 2,955
Cancer 64 | 2,499
pancreatic cancer 64 | 2,398
Multiple myeloma 62 | 1,332
primitive neuroectodermal tumor 62 | 3,035
subependymal giant cell astrocytoma 57 | 2,287
Astrocytoma, Pilocytic 56 | 3,081
lung carcinoma 55 | 2,843
breast carcinoma 53 | 1,638
ductal carcinoma in situ 53 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 51 | 1,962
Kidney cancer 50 | 2,613
adrenocortical carcinoma 49 | 1,428
pituitary cancer 48 | 1,972
group 4 medulloblastoma 46 | 1,855
diabetes mellitus 45 | 1,728
colon cancer 44 | 1,478
juvenile dermatomyositis 44 | 1,187
tuberculosis 43 | 2,010
acute quadriplegic myopathy 42 | 1,158
primary pancreatic ductal adenocarcinoma 41 | 1,109
Pick disease 37 | 1,894
interstitial cystitis 37 | 2,312
nasopharyngeal carcinoma 36 | 1,058
ulcerative colitis 36 | 1,819
Waldenstrons macroglobulinemia 35 | 765
astrocytoma 35 | 1,146
cystic fibrosis 35 | 1,696
dermatomyositis 35 | 966
non primary Sjogren syndrome sicca 34 | 891
spina bifida 32 | 1,074
acute myeloid leukemia 27 | 783
Autosomal recessive predisposition 25 | 1,442
active Crohn's disease 25 | 922
Liver Cirrhosis, Experimental 23 | 769
esophageal adenocarcinoma 23 | 737
Duchenne muscular dystrophy 22 | 601
Intellectual disability 21 | 1,016
Schizophrenia 20 | 1,160
gastric carcinoma 20 | 807
pediatric high grade glioma 20 | 1,064
Amyotrophic lateral sclerosis 19 | 451
Atopic dermatitis 18 | 952
Endometriosis 18 | 540
Rheumatoid arthritis 18 | 1,191
aldosterone-producing adenoma 18 | 665
cutaneous lupus erythematosus 18 | 1,057
gastric cancer 18 | 459
hepatocellular carcinoma 18 | 547
Breast Neoplasms 17 | 445
progressive supranuclear palsy 17 | 676
tuberculosis and treatment for 6 months 17 | 409
Alzheimer's disease 16 | 658
active ulcerative colitis 16 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 510
fibroadenoma 15 | 559
posterior fossa group B ependymoma 15 | 416
primary Sjogren syndrome 15 | 735
Dull intelligence 14 | 645
Low intelligence 14 | 645
Mammary Neoplasms 14 | 425
Mental Retardation 14 | 645
Mental deficiency 14 | 645
Neurodegenerative disease 14 | 414
Poor school performance 14 | 645
pancreatic carcinoma 14 | 562
posterior fossa group A ependymoma 13 | 468
sonic hedgehog group medulloblastoma 13 | 467
Bipolar Disorder 12 | 666
Cognitive delay 12 | 608
Global developmental delay 12 | 608
Hypertension 12 | 396
Mental and motor retardation 12 | 608
interstitial lung disease 12 | 298
medulloblastoma 12 | 720
Crohn's disease 11 | 321
Polycystic ovary syndrome 11 | 360
Prostatic Neoplasms 11 | 495
chronic rhinosinusitis 11 | 512
limb girdle muscular dystrophy 2A 11 | 213

Tissue

Digestive Tract 409 | 17,369
Endocrine System 409 | 18,159
Female tissues 409 | 17,400
Blood and immune system 408 | 16,909
Skin and soft tissues 408 | 17,230
Urinary Tract 406 | 16,678
Liver and Pancreas 404 | 16,750
Male tissues 404 | 17,142
Nervous System 404 | 16,725
Respiratory system 401 | 16,393
Cardiovascular System 394 | 15,192

Target Family

Non-IDG 262 | 12,091
Enzyme 97 | 4,145
Transcription Factor 24 | 1,400
Kinase 12 | 634
Epigenetic 10 | 242
Transporter 8 | 473
Ion Channel 3 | 344
GPCR 2 | 408

Jensen-KB Tissue

Uterine cervix 418 | 418
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acidic leucine-rich nuclear phosphoprotein 32 family member E ANP32E Tbio Non-IDG -0.82034 5.60 97
Iron-sulfur cluster assembly 1 homolog, mitochondrial ISCA1 Tbio Non-IDG -1.68100 45.7 44
GAS2-like protein 3 GAS2L3 Tbio Non-IDG -0.65733 5.79 78
Methyl-CpG-binding domain protein 3 MBD3 Tbio Transcription Factor -0.85800 7.92 309
Calcium homeostasis modulator protein 3 CALHM3 Tdark Ion Channel -0.10646 0.35 86
Beta-citrylglutamate synthase B RIMKLB Tdark Enzyme -0.33579 2.63 48
Endoplasmic reticulum-Golgi intermediate compartment protein 2 ERGIC2 Tbio Non-IDG -0.85082 8.58 126
Signal peptidase complex subunit 1 SPCS1 Tdark Enzyme -0.80900 6.46 44
Isobutyryl-CoA dehydrogenase, mitochondrial ACAD8 Tbio Enzyme -1.14784 13.9 150
Histone-lysine N-methyltransferase KMT5C KMT5C Tchem Epigenetic 1.18 0.06 46