Development Level

Tbio 164 | 11,651
Tdark 36 | 6,593
Tchem 21 | 1,388
Tclin 7 | 612

Collection

RFA-RM-18-021 4 | 328
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 22 | 979
preweaning lethality, incomple... 6 | 499
decreased vertical activity 4 | 208
embryonic lethality prior to t... 4 | 278
abnormal embryo size 3 | 220
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased circulating chloride... 3 | 30
decreased lean body mass 3 | 135
decreased total body fat amoun... 3 | 207
increased mean corpuscular hem... 3 | 96
increased or absent threshold ... 3 | 101
abnormal retina morphology 2 | 71
brachydactyly 2 | 19
decreased bone mineral content 2 | 151
decreased threshold for audito... 2 | 26
increased fasted circulating g... 2 | 76
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
syndactyly 2 | 23
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryonic autopod pla... 1 | 2
abnormal eye anterior chamber ... 1 | 9
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal hindlimb morphology 1 | 2
abnormal joint morphology 1 | 23
abnormal limb position 1 | 3
abnormal lip morphology 1 | 2
abnormal neural tube closure 1 | 46
abnormal placenta morphology 1 | 5
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal skin pigmentation 1 | 1
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal urinary bladder morph... 1 | 11
absent pinna reflex 1 | 23
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased food intake 1 | 13
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased circulating total pr... 1 | 28
increased grip strength 1 | 41
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
prenatal lethality 1 | 28
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
shortened RR interval 1 | 17
shortened ST segment 1 | 10
unresponsive to tactile stimul... 1 | 8

Disease

ovarian cancer 149 | 8,520
osteosarcoma 112 | 7,950
Carcinoma 110 | 11,493
lung cancer 94 | 4,740
medulloblastoma, large-cell 83 | 6,241
psoriasis 82 | 6,694
glioblastoma 78 | 5,792
atypical teratoid / rhabdoid tumor 65 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 56 | 2,989
ependymoma 55 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 54 | 2,955
Breast cancer 53 | 3,578
malignant mesothelioma 52 | 3,232
Multiple myeloma 50 | 1,332
pancreatic cancer 50 | 2,398
non-small cell lung cancer 49 | 2,890
invasive ductal carcinoma 46 | 2,951
lung carcinoma 45 | 2,843
group 3 medulloblastoma 44 | 4,104
adult high grade glioma 43 | 3,801
pancreatic ductal adenocarcinoma liver metastasis 41 | 1,962
Cancer 40 | 2,499
subependymal giant cell astrocytoma 38 | 2,287
interstitial cystitis 36 | 2,312
Pick disease 34 | 1,894
Waldenstrons macroglobulinemia 33 | 765
dermatomyositis 33 | 966
lung adenocarcinoma 32 | 2,716
oligodendroglioma 32 | 2,850
Astrocytoma, Pilocytic 31 | 3,081
astrocytic glioma 30 | 2,597
ductal carcinoma in situ 29 | 1,745
diabetes mellitus 28 | 1,728
cystic fibrosis 26 | 1,696
Autosomal recessive predisposition 25 | 1,442
pituitary cancer 25 | 1,972
tuberculosis 25 | 2,010
acute quadriplegic myopathy 24 | 1,158
primitive neuroectodermal tumor 24 | 3,035
Kidney cancer 23 | 2,613
astrocytoma 23 | 1,146
juvenile dermatomyositis 23 | 1,187
ulcerative colitis 23 | 1,819
adrenocortical carcinoma 22 | 1,428
colon cancer 22 | 1,478
Rheumatoid arthritis 21 | 1,191
group 4 medulloblastoma 21 | 1,855
nasopharyngeal carcinoma 18 | 1,058
Atopic dermatitis 17 | 952
breast carcinoma 17 | 1,638
primary Sjogren syndrome 17 | 735
primary pancreatic ductal adenocarcinoma 16 | 1,109
spina bifida 16 | 1,074
Epilepsy 15 | 792
Liver Cirrhosis, Experimental 15 | 769
Bipolar Disorder 14 | 666
Schizophrenia 14 | 1,160
acute myeloid leukemia 14 | 783
pediatric high grade glioma 14 | 1,064
progressive supranuclear palsy 14 | 676
Polycystic ovary syndrome 13 | 360
Seizures 13 | 596
aldosterone-producing adenoma 13 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 510
esophageal adenocarcinoma 13 | 737
non primary Sjogren syndrome sicca 13 | 891
Duchenne muscular dystrophy 12 | 601
Prostatic Neoplasms 12 | 495
pancreatic carcinoma 12 | 562
Intellectual disability 11 | 1,016
active Crohn's disease 11 | 922
active ulcerative colitis 11 | 764
gastric carcinoma 11 | 807
medulloblastoma 11 | 720
Carcinoma, Hepatocellular 10 | 228
Down syndrome 10 | 499
Failure to gain weight 10 | 365
Pediatric failure to thrive 10 | 365
cutaneous lupus erythematosus 10 | 1,057
Cognitive delay 9 | 608
Endometriosis 9 | 540
Global developmental delay 9 | 608
Hepatomegaly 9 | 285
Liver carcinoma 9 | 240
Mental and motor retardation 9 | 608
Muscle hypotonia 9 | 571
Obesity 9 | 678
hereditary spastic paraplegia 9 | 318
Breast Neoplasms 8 | 445
Dull intelligence 8 | 645
Hypertension 8 | 396
Low intelligence 8 | 645
Mammary Neoplasms 8 | 425
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
sonic hedgehog group medulloblastoma 8 | 467
tuberculosis and treatment for 6 months 8 | 409
Nystagmus 7 | 317

Tissue

Female tissues 224 | 17,400
Blood and immune system 223 | 16,909
Digestive Tract 223 | 17,369
Endocrine System 223 | 18,159
Skin and soft tissues 223 | 17,230
Urinary Tract 223 | 16,678
Liver and Pancreas 222 | 16,750
Male tissues 222 | 17,142
Respiratory system 222 | 16,393
Nervous System 220 | 16,725
Cardiovascular System 215 | 15,192

Target Family

Non-IDG 125 | 12,091
Enzyme 73 | 4,145
Transcription Factor 10 | 1,400
Kinase 8 | 634
Transporter 5 | 473
Ion Channel 3 | 344
Epigenetic 2 | 242
GPCR 1 | 408
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Urinary bladder 228 | 228
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
WW domain-containing adapter protein with coiled-coil WAC Tbio Non-IDG -1.93384 84.9 87
Programmed cell death protein 10 PDCD10 Tbio Non-IDG -1.63894 37.2 185
High affinity cationic amino acid transporter 1 SLC7A1 Tbio Transporter -2.71485 501.4 143
COMM domain-containing protein 10 COMMD10 Tdark Non-IDG -0.12222 1.52 104
DNA-directed RNA polymerase I subunit RPA43 TWISTNB Tdark Enzyme -0.05799 1.13 69
Zinc transporter ZIP1 SLC39A1 Tbio Transporter -1.89903 75.9 61
4-hydroxy-2-oxoglutarate aldolase, mitochondrial HOGA1 Tbio Enzyme -1.37549 1.73 7
Chymotrypsin-C CTRC Tchem Enzyme -2.46349 293.5 81
Serine palmitoyltransferase 3 SPTLC3 Tbio Enzyme -1.26166 18.5 24