Development Level

Tbio 142 | 10,625
Tdark 44 | 7,003
Tchem 32 | 1,890
Tclin 8 | 602

Collection

Eligible Ion Channel Proteins 2 | 117
Eligible Kinase Proteins 1 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 12 | 633
abnormal retina morphology 3 | 100
decreased circulating HDL chol... 3 | 77
increased mean corpuscular hem... 3 | 93
abnormal lens morphology 2 | 73
decreased granulocyte number 2 | 8
decreased lean body mass 2 | 195
embryonic lethality prior to t... 2 | 187
increased B cell number 2 | 23
increased grip strength 2 | 83
increased heart rate 2 | 17
increased leukocyte cell numbe... 2 | 37
increased mature B cell number 2 | 12
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
increased sacral vertebrae num... 2 | 62
prenatal lethality prior to he... 2 | 64
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal embryo size 1 | 112
abnormal eye anterior chamber ... 1 | 3
abnormal hindbrain development 1 | 24
abnormal hindlimb morphology 1 | 2
abnormal kidney morphology 1 | 30
abnormal limb position 1 | 3
abnormal lip morphology 1 | 2
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal seminal vesicle morph... 1 | 47
abnormal skin pigmentation 1 | 1
abnormal sleep behavior 1 | 63
cataract 1 | 26
decreased CD4-positive, CD25-p... 1 | 24
decreased CD8-positive, alpha-... 1 | 26
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 53
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating magnesiu... 1 | 11
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased eosinophil cell numb... 1 | 41
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased hemoglobin content 1 | 53
decreased late germinal center... 1 | 2
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased monocyte cell number 1 | 28
decreased myeloid cell number ... 1 | 1
decreased pre-pro B cell numbe... 1 | 2
decreased pro-B cell number 1 | 2
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
enlarged heart 1 | 111
hyperactivity 1 | 108
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased CD5-positive Ly6C-po... 1 | 4
increased T cell number 1 | 15
increased bone mineral content 1 | 92
increased circulating LDL chol... 1 | 15
increased circulating aspartat... 1 | 17
increased circulating creatine... 1 | 2
increased circulating total pr... 1 | 20
increased early germinal cente... 1 | 2
increased effector memory CD4-... 1 | 15
increased fasted circulating g... 1 | 68
increased immature B cell numb... 1 | 1
increased pre-B cell number 1 | 1
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
polydactyly 1 | 22
short tibia 1 | 82
shortened PQ interval 1 | 6
shortened PR interval 1 | 5
shortened RR interval 1 | 19
shortened ST segment 1 | 9

Disease

ovarian cancer 148 | 8,484
osteosarcoma 112 | 7,933
lung cancer 93 | 4,466
psoriasis 84 | 6,685
medulloblastoma, large-cell 83 | 6,234
glioblastoma 74 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 63 | 3,289
atypical teratoid / rhabdoid tumor 58 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 56 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 54 | 2,956
malignant mesothelioma 51 | 3,162
Multiple myeloma 50 | 1,327
pancreatic cancer 50 | 2,300
Breast cancer 49 | 3,094
non-small cell lung cancer 47 | 2,798
invasive ductal carcinoma 46 | 2,950
lung carcinoma 45 | 2,844
subependymal giant cell astrocytoma 39 | 2,287
Cancer 37 | 2,346
pancreatic ductal adenocarcinoma liver metastasis 37 | 1,795
interstitial cystitis 36 | 2,299
Pick disease 35 | 1,893
Waldenstrons macroglobulinemia 34 | 765
dermatomyositis 33 | 933
lung adenocarcinoma 33 | 2,713
oligodendroglioma 33 | 2,849
pilocytic astrocytoma 33 | 3,086
adult high grade glioma 30 | 2,148
ulcerative colitis 30 | 2,087
astrocytic glioma 29 | 2,241
ductal carcinoma in situ 29 | 1,745
group 3 medulloblastoma 29 | 2,254
ependymoma 28 | 2,514
pediatric high grade glioma 28 | 2,712
astrocytoma 26 | 1,493
pituitary cancer 26 | 1,972
cystic fibrosis 25 | 1,665
diabetes mellitus 25 | 1,663
primitive neuroectodermal tumor 25 | 3,031
acute quadriplegic myopathy 24 | 1,157
colon cancer 23 | 1,475
juvenile dermatomyositis 23 | 1,189
adrenocortical carcinoma 22 | 1,427
posterior fossa group A ependymoma 22 | 1,511
Rheumatoid Arthritis 21 | 1,160
tuberculosis 21 | 1,557
medulloblastoma 20 | 1,524
primary pancreatic ductal adenocarcinoma 20 | 1,271
nasopharyngeal carcinoma 19 | 1,056
sonic hedgehog group medulloblastoma 19 | 1,482
Atopic dermatitis 17 | 944
breast carcinoma 17 | 1,614
primary Sjogren syndrome 17 | 789
group 4 medulloblastoma 16 | 1,875
spina bifida 16 | 1,064
Carcinoma 15 | 2,147
acute myeloid leukemia 14 | 780
progressive supranuclear palsy 14 | 674
Polycystic Ovary Syndrome 13 | 332
aldosterone-producing adenoma 13 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 13 | 499
esophageal adenocarcinoma 13 | 737
pancreatic carcinoma 13 | 567
Duchenne muscular dystrophy 12 | 602
gastric carcinoma 12 | 832
non primary Sjogren syndrome sicca 12 | 840
posterior fossa group B ependymoma 12 | 1,530
Prostatic Neoplasms 11 | 471
active Crohn's disease 11 | 918
tuberculosis and treatment for 6 months 11 | 686
Down syndrome 10 | 548
cutaneous lupus erythematosus 10 | 1,056
Endometriosis 9 | 535
Liver carcinoma 9 | 217
Obesity 9 | 616
atypical teratoid/rhabdoid tumor 9 | 1,095
hereditary spastic paraplegia 9 | 313
IGA Glomerulonephritis 8 | 454
Mammary Neoplasms 8 | 410
Peripheral Neuropathy 8 | 303
Amyotrophic Lateral Sclerosis 7 | 431
Asthma 7 | 349
Kidney disease 7 | 396
chronic rhinosinusitis 7 | 512
hepatocellular carcinoma 7 | 532
non-small cell lung carcinoma 7 | 413
Alzheimer's disease 6 | 644
Hypertension 6 | 287
Intellectual disability 6 | 573
Liver disease 6 | 219
Pancreatitis 6 | 97
Stomach Neoplasms 6 | 282
mucosa-associated lymphoid tissue lymphoma 6 | 480
urothelial carcinoma 6 | 318
Contact Dermatitis 5 | 80
Crohn's disease 5 | 304
Hypersensitivity reaction type II disease 5 | 235
fibroadenoma 5 | 557
gastric cancer 5 | 430
nephrosclerosis 5 | 329

Tissue

Female tissues 224 | 18,647
Male tissues 224 | 17,969
Blood and immune system 223 | 17,995
Cardiovascular System 223 | 17,958
Digestive Tract 223 | 18,473
Endocrine System 223 | 18,512
Liver and Pancreas 223 | 18,136
Nervous System 223 | 18,561
Respiratory system 223 | 17,484
Urinary Tract 223 | 18,444
Skin and soft tissues 221 | 18,115

Target Family

Non-IDG 124 | 11,971
Enzyme 73 | 4,146
Transcription Factor 9 | 1,400
Kinase 8 | 634
Transporter 5 | 473
Ion Channel 3 | 341
Epigenetic 2 | 242
GPCR 1 | 406
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Urinary bladder 226 | 226
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Protein-tyrosine kinase 6 PTK6 Tchem Kinase -2.14303 167.1 320
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Ferritin light chain FTL Tbio Non-IDG -2.37909 242.0 430
U2 snRNP-associated SURP motif-containing protein U2SURP Tdark Non-IDG -0.36798 2.16 82
Fibrinogen-like protein 1 FGL1 Tbio Non-IDG -1.32495 25.3 213
Nucleoporin-like protein 2 NUPL2 Tbio Non-IDG -0.99049 10.1 66
Bladder cancer-associated protein BLCAP Tbio Non-IDG -1.44304 29.7 26
Gamma-glutamylcyclotransferase GGCT Tbio Enzyme -2.15784 135.0 114
Ral GTPase-activating protein subunit alpha-2 RALGAPA2 Tdark Enzyme -0.60322 4.19 29