Development Level

Tbio 212 | 10,625
Tdark 82 | 7,003
Tchem 33 | 1,890
Tclin 16 | 602

Collection

Eligible non-olfactory GPCR Proteins 2 | 143
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 23 | 633
embryonic lethality prior to t... 9 | 187
decreased total body fat amoun... 8 | 186
decreased lean body mass 7 | 195
embryonic lethality prior to o... 7 | 148
abnormal embryo size 5 | 112
decreased body weight 4 | 174
decreased circulating glucose ... 4 | 121
decreased circulating insulin ... 4 | 75
embryonic growth retardation 4 | 28
prenatal lethality 4 | 16
abnormal coat/hair pigmentatio... 3 | 54
abnormal retina morphology 3 | 100
decreased body length 3 | 108
decreased bone mineral content 3 | 157
decreased grip strength 3 | 123
decreased threshold for audito... 3 | 32
increased circulating sodium l... 3 | 71
increased exploration in new e... 3 | 56
increased lean body mass 3 | 107
increased mean corpuscular hem... 3 | 93
short tibia 3 | 82
abnormal behavior 2 | 226
abnormal bone structure 2 | 131
abnormal embryo turning 2 | 15
abnormal lens morphology 2 | 73
abnormal neural tube closure 2 | 37
decreased circulating calcium ... 2 | 33
decreased circulating triglyce... 2 | 83
decreased mean corpuscular vol... 2 | 50
enlarged heart 2 | 111
increased bone mineral density 2 | 52
increased fasted circulating g... 2 | 68
increased mean platelet volume 2 | 19
male infertility 2 | 62
microphthalmia 2 | 15
prenatal lethality prior to he... 2 | 64
preweaning lethality, incomple... 2 | 260
abnormal brain morphology 1 | 6
abnormal cornea morphology 1 | 24
abnormal craniofacial morpholo... 1 | 12
abnormal forebrain morphology 1 | 4
abnormal head shape 1 | 4
abnormal heart morphology 1 | 51
abnormal locomotor activation 1 | 26
abnormal neural tube morpholog... 1 | 8
abnormal placenta morphology 1 | 4
abnormal placenta size 1 | 10
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin coloration 1 | 18
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
abnormal tail bud morphology 1 | 6
anophthalmia 1 | 20
decreased bone mineral density 1 | 126
decreased circulating fructosa... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating serum al... 1 | 79
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
edema 1 | 11
enlarged lymph nodes 1 | 27
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating aspartat... 1 | 17
increased circulating free fat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating glycerol... 1 | 11
increased circulating phosphat... 1 | 24
increased circulating total pr... 1 | 20
increased effector memory CD4-... 1 | 15
increased gamma-delta T cell n... 1 | 16
increased granulocyte number 1 | 8
increased grip strength 1 | 83
increased mature B cell number 1 | 12
increased respiratory quotient 1 | 12
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
pallor 1 | 13
prolonged QRS complex duration 1 | 2
shortened QT interval 1 | 4
shortened RR interval 1 | 19
small adrenal glands 1 | 15
small spleen 1 | 11
small superior vagus ganglion 1 | 20

Disease

ovarian cancer 236 | 8,484
osteosarcoma 175 | 7,933
lung cancer 109 | 4,466
glioblastoma 99 | 5,572
psoriasis 98 | 6,685
medulloblastoma, large-cell 96 | 6,234
Multiple myeloma 72 | 1,327
pancreatic ductal adenocarcinoma liver metastasis 63 | 1,795
group 3 medulloblastoma 59 | 2,254
atypical teratoid / rhabdoid tumor 58 | 4,369
Breast cancer 57 | 3,094
non-small cell lung cancer 55 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 53 | 3,289
malignant mesothelioma 48 | 3,162
pediatric high grade glioma 47 | 2,712
invasive ductal carcinoma 45 | 2,950
lung adenocarcinoma 43 | 2,713
diabetes mellitus 42 | 1,663
primitive neuroectodermal tumor 42 | 3,031
ependymoma 41 | 2,514
interstitial cystitis 41 | 2,299
tuberculosis 41 | 1,557
pilocytic astrocytoma 40 | 3,086
astrocytoma 39 | 1,493
Waldenstrons macroglobulinemia 38 | 765
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,988
pancreatic cancer 38 | 2,300
ulcerative colitis 38 | 2,087
subependymal giant cell astrocytoma 37 | 2,287
dermatomyositis 36 | 933
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,956
lung carcinoma 36 | 2,844
oligodendroglioma 36 | 2,849
acute quadriplegic myopathy 31 | 1,157
Rheumatoid Arthritis 29 | 1,160
non primary Sjogren syndrome sicca 29 | 840
acute myeloid leukemia 28 | 780
primary Sjogren syndrome 28 | 789
Cancer 27 | 2,346
astrocytic glioma 27 | 2,241
juvenile dermatomyositis 27 | 1,189
cutaneous lupus erythematosus 26 | 1,056
Pick disease 25 | 1,893
primary pancreatic ductal adenocarcinoma 23 | 1,271
group 4 medulloblastoma 22 | 1,875
breast carcinoma 20 | 1,614
medulloblastoma 20 | 1,524
atypical teratoid/rhabdoid tumor 19 | 1,095
gastric carcinoma 18 | 832
IGA Glomerulonephritis 17 | 454
adrenocortical carcinoma 17 | 1,427
adult high grade glioma 17 | 2,148
tuberculosis and treatment for 6 months 17 | 686
ductal carcinoma in situ 16 | 1,745
mucosa-associated lymphoid tissue lymphoma 16 | 480
posterior fossa group A ependymoma 16 | 1,511
posterior fossa group B ependymoma 16 | 1,530
active Crohn's disease 15 | 918
aldosterone-producing adenoma 14 | 664
esophageal adenocarcinoma 14 | 737
pituitary cancer 14 | 1,972
Diabetes mellitus type 2 13 | 69
Treatment Refractory Type 2 Diabetes Mellitus 13 | 53
cystic fibrosis 13 | 1,665
Carcinoma 12 | 2,147
head and neck cancer and chronic obstructive pulmonary disease 12 | 237
spina bifida 12 | 1,064
active ulcerative colitis 11 | 477
colon cancer 11 | 1,475
sonic hedgehog group medulloblastoma 11 | 1,482
Down syndrome 10 | 548
Intellectual disability 10 | 573
hereditary spastic paraplegia 10 | 313
Amyotrophic Lateral Sclerosis 9 | 431
Duchenne muscular dystrophy 9 | 602
Mammary Neoplasms 9 | 410
Obesity 9 | 616
hepatocellular carcinoma 9 | 532
Alzheimer's disease 8 | 644
Multiple Sclerosis 8 | 498
nasopharyngeal carcinoma 8 | 1,056
nephrosclerosis 8 | 329
sarcoidosis 8 | 358
Atherosclerosis 7 | 275
Coronary artery disease 7 | 240
Polycystic Ovary Syndrome 7 | 332
Prostatic Neoplasms 7 | 471
Stomach Neoplasms 7 | 282
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 499
pancreatic carcinoma 7 | 567
tuberculosis and treatment for 3 months 7 | 327
Anemia 6 | 252
Cardiovascular system disease 6 | 194
Chronic Lymphocytic Leukemia 6 | 242
Kidney disease 6 | 396
Parkinson's disease 6 | 364
chronic lymphosyte leukemia 6 | 232
Becker muscular dystrophy 5 | 187
inflammatory breast cancer 5 | 404
periodontitis 5 | 269

Tissue

Blood and immune system 343 | 17,995
Cardiovascular System 343 | 17,958
Endocrine System 343 | 18,512
Female tissues 343 | 18,647
Liver and Pancreas 343 | 18,136
Male tissues 343 | 17,969
Digestive Tract 342 | 18,473
Nervous System 342 | 18,561
Respiratory system 342 | 17,484
Urinary Tract 341 | 18,444
Skin and soft tissues 339 | 18,115

Target Family

Non-IDG 213 | 11,971
Enzyme 102 | 4,146
Transcription Factor 8 | 1,400
GPCR 6 | 406
Epigenetic 4 | 242
Kinase 4 | 634
Transporter 3 | 473
Ion Channel 2 | 341
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Umbilical cord blood 343 | 343
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial PGS1 Tdark Enzyme -0.35218 2.20 100
39S ribosomal protein L37, mitochondrial MRPL37 Tdark Non-IDG -0.30103 2.00 47
Serine/arginine repetitive matrix protein 2 SRRM2 Tbio Non-IDG -1.90106 71.6 51
Transmembrane protein 258 TMEM258 Tdark Non-IDG 0.12 1.54 5
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.90528 8199.7 1129
Very-long-chain enoyl-CoA reductase TECR Tbio Enzyme -2.58601 380.5 85
Platelet basic protein PPBP Tbio Non-IDG -3.18113 1540.1 348
Sialic acid-binding Ig-like lectin 15 SIGLEC15 Tbio Non-IDG -0.52504 6.12 82
Ubiquinone biosynthesis protein COQ9, mitochondrial COQ9 Tbio Non-IDG -1.98869 99.9 68
T-complex protein 1 subunit epsilon CCT5 Tbio Non-IDG -1.39059 24.5 183