Development Level

Tbio 230 | 11,651
Tdark 72 | 6,593
Tchem 26 | 1,388
Tclin 16 | 612

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 35 | 979
embryonic lethality prior to t... 10 | 278
abnormal embryo size 9 | 220
embryonic lethality prior to o... 9 | 239
decreased total body fat amoun... 7 | 207
preweaning lethality, incomple... 7 | 499
enlarged heart 6 | 210
abnormal heart morphology 5 | 162
decreased vertical activity 5 | 208
embryonic growth retardation 5 | 106
abnormal behavior 4 | 298
decreased body weight 4 | 161
decreased circulating insulin ... 4 | 76
decreased grip strength 4 | 116
hypoactivity 4 | 132
increased lean body mass 4 | 172
male infertility 4 | 123
prenatal lethality 4 | 28
short tibia 4 | 97
abnormal coat-hair pigmentatio... 3 | 64
abnormal lens morphology 3 | 81
abnormal neural tube closure 3 | 46
cataract 3 | 92
decreased lean body mass 3 | 135
decreased mean corpuscular vol... 3 | 79
increased circulating sodium l... 3 | 71
increased total body fat amoun... 3 | 134
prenatal lethality prior to he... 3 | 87
abnormal bone structure 2 | 187
abnormal embryo turning 2 | 31
abnormal forebrain morphology 2 | 10
abnormal kidney morphology 2 | 65
abnormal retina morphology 2 | 71
abnormal skin coloration 2 | 25
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
impaired pupillary reflex 2 | 26
increased circulating aspartat... 2 | 15
increased mean corpuscular hem... 2 | 96
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
microphthalmia 2 | 26
pallor 2 | 34
small superior vagus ganglion 2 | 74
abnormal bone mineralization 1 | 38
abnormal brain morphology 1 | 13
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal head shape 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal midbrain morphology 1 | 10
abnormal neural tube morpholog... 1 | 12
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal posture 1 | 2
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spine curvature 1 | 9
abnormal tail bud morphology 1 | 8
absent testes 1 | 6
anophthalmia 1 | 33
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glycerol... 1 | 16
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
edema 1 | 59
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating glycerol... 1 | 9
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased prepulse inhibition 1 | 32
shortened RR interval 1 | 17
small adrenal glands 1 | 16
small spleen 1 | 19

Disease

ovarian cancer 238 | 8,520
osteosarcoma 176 | 7,950
Carcinoma 139 | 11,493
lung cancer 111 | 4,740
glioblastoma 101 | 5,792
psoriasis 98 | 6,694
medulloblastoma, large-cell 97 | 6,241
Multiple myeloma 73 | 1,332
atypical teratoid / rhabdoid tumor 72 | 5,112
group 3 medulloblastoma 71 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 67 | 1,962
ependymoma 60 | 4,679
Breast cancer 59 | 3,578
non-small cell lung cancer 56 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 53 | 3,291
tuberculosis 50 | 2,010
malignant mesothelioma 49 | 3,232
invasive ductal carcinoma 45 | 2,951
diabetes mellitus 44 | 1,728
lung adenocarcinoma 43 | 2,716
primitive neuroectodermal tumor 42 | 3,035
Astrocytoma, Pilocytic 41 | 3,081
interstitial cystitis 41 | 2,312
adult high grade glioma 39 | 3,801
Waldenstrons macroglobulinemia 38 | 765
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,989
pancreatic cancer 38 | 2,398
Autosomal recessive predisposition 37 | 1,442
subependymal giant cell astrocytoma 37 | 2,287
dermatomyositis 36 | 966
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,955
lung carcinoma 36 | 2,843
oligodendroglioma 36 | 2,850
ulcerative colitis 34 | 1,819
astrocytic glioma 33 | 2,597
astrocytoma 33 | 1,146
acute quadriplegic myopathy 31 | 1,158
Cancer 30 | 2,499
non primary Sjogren syndrome sicca 30 | 891
Rheumatoid arthritis 28 | 1,191
acute myeloid leukemia 28 | 783
group 4 medulloblastoma 28 | 1,855
primary Sjogren syndrome 28 | 735
juvenile dermatomyositis 27 | 1,187
cutaneous lupus erythematosus 26 | 1,057
Intellectual disability 25 | 1,016
Pick disease 25 | 1,894
pediatric high grade glioma 25 | 1,064
Cognitive delay 22 | 608
Global developmental delay 22 | 608
Mental and motor retardation 22 | 608
Kidney cancer 20 | 2,613
breast carcinoma 20 | 1,638
primary pancreatic ductal adenocarcinoma 20 | 1,109
Dull intelligence 19 | 645
Low intelligence 19 | 645
Mental Retardation 19 | 645
Mental deficiency 19 | 645
Muscle hypotonia 19 | 571
Poor school performance 19 | 645
adrenocortical carcinoma 17 | 1,428
gastric carcinoma 17 | 807
mucosa-associated lymphoid tissue lymphoma 17 | 484
Epilepsy 16 | 792
Failure to gain weight 16 | 365
Pediatric failure to thrive 16 | 365
ductal carcinoma in situ 16 | 1,745
active Crohn's disease 15 | 922
active ulcerative colitis 15 | 764
aldosterone-producing adenoma 14 | 665
cystic fibrosis 14 | 1,696
esophageal adenocarcinoma 14 | 737
pituitary cancer 14 | 1,972
Diabetes mellitus type 2 13 | 69
Liver Cirrhosis, Experimental 13 | 769
Seizures 13 | 596
Treatment Refractory Type 2 Diabetes Mellitus 13 | 53
spina bifida 13 | 1,074
tuberculosis and treatment for 6 months 13 | 409
head and neck cancer and chronic obstructive pulmonary disease 12 | 239
Amyotrophic lateral sclerosis 11 | 451
Anemia 11 | 365
Cerebellar Ataxia 11 | 304
Schizophrenia 11 | 1,160
Short stature 11 | 531
colon cancer 11 | 1,478
Multiple Sclerosis 10 | 540
Obesity 10 | 678
hepatocellular carcinoma 10 | 547
hereditary spastic paraplegia 10 | 318
Breast Neoplasms 9 | 445
Disease Models, Animal 9 | 155
Duchenne muscular dystrophy 9 | 601
Mammary Neoplasms 9 | 425
Bipolar Disorder 8 | 666
Down syndrome 8 | 499
Hepatomegaly 8 | 285
Nystagmus 8 | 317
nasopharyngeal carcinoma 8 | 1,058
nephrosclerosis 8 | 333

Tissue

Blood and immune system 343 | 16,909
Digestive Tract 343 | 17,369
Urinary Tract 343 | 16,678
Endocrine System 342 | 18,159
Female tissues 342 | 17,400
Liver and Pancreas 342 | 16,750
Skin and soft tissues 342 | 17,230
Respiratory system 341 | 16,393
Male tissues 340 | 17,142
Nervous System 339 | 16,725
Cardiovascular System 338 | 15,192

Target Family

Non-IDG 214 | 12,091
Enzyme 102 | 4,145
Transcription Factor 8 | 1,400
GPCR 6 | 408
Epigenetic 4 | 242
Kinase 4 | 634
Transporter 3 | 473
Ion Channel 2 | 344
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Umbilical cord blood 344 | 344
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DBIRD complex subunit ZNF326 ZNF326 Tbio Non-IDG -0.42207 3.94 120
Trafficking protein particle complex subunit 2-like protein TRAPPC2L Tdark Non-IDG -0.18066 0.74 35
Probable ergosterol biosynthetic protein 28 ERG28 Tdark Non-IDG -1.25331 16.7 40
Activator of 90 kDa heat shock protein ATPase homolog 1 AHSA1 Tbio Enzyme -1.65208 50.3 564
Basic leucine zipper and W2 domain-containing protein 2 BZW2 Tbio Non-IDG -0.20261 1.21 83
Alpha-(1,3)-fucosyltransferase 7 FUT7 Tchem Enzyme -1.85814 81.0 121
Nuclear-interacting partner of ALK ZC3HC1 Tbio Non-IDG -2.13812 136.0 171
BRISC and BRCA1-A complex member 1 BABAM1 Tbio Non-IDG -1.20557 16.7 162
39S ribosomal protein L42, mitochondrial MRPL42 Tdark Non-IDG 0.02 0.40 139
COMM domain-containing protein 10 COMMD10 Tdark Non-IDG -0.12222 1.52 104