Targets

Target Filters...

This is where graphics are reside..

Name	Gene	Development Level	Target Family	Log Novelty	Pubmed Score	Antibody Count
Fc receptor-like protein 3	FCRL3	Tbio	Non-IDG	-1.78373	68.9	58
COBW domain-containing protein 1	CBWD1	Tbio	Non-IDG	-1.58263	37.3	79
DnaJ homolog subfamily A member 4	DNAJA4	Tbio	Non-IDG	-0.49544	2.67	105
Cell cycle control protein 50A	TMEM30A	Tbio	Non-IDG	-1.01830	9.66	25
Sequestosome-1	SQSTM1	Tbio	Non-IDG	-2.71345	536.6	655
Calcium-dependent secretion activator 2	CADPS2	Tbio	Non-IDG	-1.08328	13.0	28
GATA zinc finger domain-containing protein 1	GATAD1	Tbio	Transcription Factor	-0.78711	6.39	100
TNF receptor-associated factor 6	TRAF6	Tbio	Non-IDG	-2.67984	438.1	349
CHRNA7-FAM7A fusion protein	CHRFAM7A	Tbio	Non-IDG	-1.78124	84.1	71
Regulation of nuclear pre-mRNA domain-containing protein 1A	RPRD1A	Tbio	Non-IDG	-0.74843	7.15	73

	Tbio	316 \| 10,625
	Tdark	121 \| 7,003
	Tchem	65 \| 1,890
	Tclin	17 \| 602

	Eligible Kinase Proteins	6 \| 134
	Eligible Ion Channel Proteins	2 \| 117
	Eligible non-olfactory GPCR Proteins	1 \| 145

	preweaning lethality, complete...	19 \| 633
	decreased lean body mass	10 \| 195
	abnormal behavior	9 \| 226
	preweaning lethality, incomple...	9 \| 260
	decreased total body fat amoun...	8 \| 186
	increased mean corpuscular vol...	7 \| 91
	decreased body weight	6 \| 174
	decreased hematocrit	6 \| 25
	decreased hemoglobin content	6 \| 53
	abnormal lens morphology	5 \| 73
	decreased bone mineral content	5 \| 157
	decreased erythrocyte cell num...	5 \| 43
	embryonic lethality prior to t...	5 \| 187
	hypoactivity	5 \| 89
	abnormal bone structure	4 \| 131
	decreased bone mineral density	4 \| 126
	decreased caudal vertebrae num...	4 \| 49
	decreased circulating glucose ...	4 \| 121
	decreased circulating serum al...	4 \| 79
	decreased mean corpuscular hem...	4 \| 34
	decreased prepulse inhibition	4 \| 52
	embryonic lethality prior to o...	4 \| 148
	increased circulating alkaline...	4 \| 119
	increased circulating creatini...	4 \| 29
	increased circulating serum al...	4 \| 25
	increased exploration in new e...	4 \| 56
	abnormal bone mineralization	3 \| 55
	abnormal embryo size	3 \| 112
	abnormal locomotor activation	3 \| 26
	abnormal retina morphology	3 \| 100
	abnormal retinal pigmentation	3 \| 61
	abnormal skin morphology	3 \| 23
	abnormal spleen morphology	3 \| 36
	decreased circulating iron lev...	3 \| 25
	decreased circulating triglyce...	3 \| 83
	decreased fasted circulating g...	3 \| 49
	decreased grip strength	3 \| 123
	decreased heart weight	3 \| 44
	decreased leukocyte cell numbe...	3 \| 54
	enlarged heart	3 \| 111
	increased B cell number	3 \| 23
	increased blood urea nitrogen ...	3 \| 44
	increased bone mineral content	3 \| 92
	increased lean body mass	3 \| 107
	increased or absent threshold ...	3 \| 128
	limb grasping	3 \| 35
	thrombocytosis	3 \| 23
	abnormal coat/hair pigmentatio...	2 \| 54
	abnormal eye morphology	2 \| 38
	abnormal heart morphology	2 \| 51
	abnormal posture	2 \| 5
	abnormal rib morphology	2 \| 28
	abnormal sleep behavior	2 \| 63
	abnormal startle reflex	2 \| 14
	abnormal thoracic vertebrae mo...	2 \| 16
	abnormal vertebral arch morpho...	2 \| 9
	decreased CD8-positive, alpha-...	2 \| 26
	decreased T cell number	2 \| 31
	decreased body length	2 \| 108
	decreased cervical vertebrae n...	2 \| 12
	decreased circulating HDL chol...	2 \| 77
	decreased circulating alkaline...	2 \| 41
	decreased circulating choleste...	2 \| 85
	decreased circulating free fat...	2 \| 39
	decreased circulating glycerol...	2 \| 19
	decreased circulating phosphat...	2 \| 15
	decreased circulating thyroxin...	2 \| 5
	decreased circulating total pr...	2 \| 41
	decreased granulocyte number	2 \| 8
	decreased mean corpuscular vol...	2 \| 50
	decreased mean platelet volume	2 \| 12
	decreased rib number	2 \| 59
	decreased startle reflex	2 \| 48
	enlarged lymph nodes	2 \| 27
	enlarged urinary bladder	2 \| 4
	hydrops fetalis	2 \| 22
	impaired glucose tolerance	2 \| 52
	increased body length	2 \| 20
	increased circulating amylase ...	2 \| 13
	increased circulating calcium ...	2 \| 32
	increased circulating chloride...	2 \| 43
	increased circulating phosphat...	2 \| 24
	increased circulating thyroxin...	2 \| 7
	increased circulating total pr...	2 \| 20
	increased grip strength	2 \| 83
	increased hematocrit	2 \| 36
	increased hemoglobin content	2 \| 45
	increased leukocyte cell numbe...	2 \| 37
	increased mean corpuscular hem...	2 \| 93
	increased mean corpuscular hem...	2 \| 25
	increased rib number	2 \| 41
	increased sacral vertebrae num...	2 \| 62
	increased vertical activity	2 \| 18
	tremors	2 \| 34
	vertebral fusion	2 \| 23
	vertebral transformation	2 \| 12
	abnormal behavioral response t...	1 \| 52
	abnormal cranium morphology	1 \| 32
	abnormal tooth morphology	1 \| 24
	decreased NK cell number	1 \| 16

	ovarian cancer	315 \| 8,492
	osteosarcoma	289 \| 7,933
	psoriasis	214 \| 6,685
	medulloblastoma, large-cell	201 \| 6,234
	glioblastoma	186 \| 5,572
	lung cancer	159 \| 4,473
	atypical teratoid / rhabdoid tumor	145 \| 4,369
	intraductal papillary-mucinous adenoma (IPMA)	139 \| 2,956
	intraductal papillary-mucinous neoplasm (IPMN)	137 \| 3,289
	Breast cancer	125 \| 3,099
	intraductal papillary-mucinous carcinoma (IPMC)	121 \| 2,988
	malignant mesothelioma	111 \| 3,163
	non-small cell lung cancer	111 \| 2,798
	invasive ductal carcinoma	110 \| 2,950
	lung adenocarcinoma	104 \| 2,714
	oligodendroglioma	104 \| 2,849
	interstitial cystitis	102 \| 2,299
	lung carcinoma	101 \| 2,844
	pilocytic astrocytoma	101 \| 3,086
	pancreatic cancer	97 \| 2,300
	primitive neuroectodermal tumor	93 \| 3,031
	pediatric high grade glioma	90 \| 2,712
	ependymoma	89 \| 2,514
	astrocytic glioma	84 \| 2,241
	subependymal giant cell astrocytoma	82 \| 2,287
	ulcerative colitis	82 \| 2,087
	pituitary cancer	78 \| 1,972
	Cancer	76 \| 2,346
	group 4 medulloblastoma	76 \| 1,875
	Pick disease	74 \| 1,893
	Carcinoma	73 \| 2,147
	pancreatic ductal adenocarcinoma liver metastasis	70 \| 1,795
	adult high grade glioma	69 \| 2,148
	ductal carcinoma in situ	69 \| 1,745
	cystic fibrosis	68 \| 1,670
	group 3 medulloblastoma	63 \| 2,254
	juvenile dermatomyositis	60 \| 1,189
	acute quadriplegic myopathy	58 \| 1,157
	tuberculosis	58 \| 1,563
	posterior fossa group B ependymoma	57 \| 1,530
	spina bifida	54 \| 1,064
	medulloblastoma	53 \| 1,524
	adrenocortical carcinoma	52 \| 1,427
	breast carcinoma	52 \| 1,614
	nasopharyngeal carcinoma	51 \| 1,056
	colon cancer	49 \| 1,475
	diabetes mellitus	49 \| 1,663
	primary pancreatic ductal adenocarcinoma	49 \| 1,271
	Multiple myeloma	48 \| 1,328
	Rheumatoid Arthritis	48 \| 1,171
	astrocytoma	48 \| 1,493
	posterior fossa group A ependymoma	44 \| 1,511
	cutaneous lupus erythematosus	41 \| 1,056
	sonic hedgehog group medulloblastoma	40 \| 1,482
	active Crohn's disease	38 \| 918
	tuberculosis and treatment for 6 months	37 \| 686
	chronic rhinosinusitis	35 \| 512
	atypical teratoid/rhabdoid tumor	34 \| 1,095
	primary Sjogren syndrome	34 \| 789
	Atopic dermatitis	33 \| 944
	hepatocellular carcinoma	33 \| 550
	Waldenstrons macroglobulinemia	32 \| 765
	aldosterone-producing adenoma	32 \| 664
	acute myeloid leukemia	31 \| 785
	dermatomyositis	31 \| 967
	gastric carcinoma	31 \| 832
	autosomal dominant Emery-Dreifuss muscular dystrophy	30 \| 499
	progressive supranuclear palsy	29 \| 674
	fibroadenoma	26 \| 557
	pancreatic carcinoma	26 \| 567
	Down syndrome	25 \| 548
	esophageal adenocarcinoma	25 \| 737
	IGA Glomerulonephritis	24 \| 454
	mucosa-associated lymphoid tissue lymphoma	24 \| 480
	Alzheimer's disease	23 \| 644
	Duchenne muscular dystrophy	23 \| 602
	Obesity	22 \| 616
	non-small cell lung carcinoma	22 \| 413
	Intellectual disability	21 \| 573
	gastric cancer	21 \| 436
	Amyotrophic Lateral Sclerosis	20 \| 432
	head and neck cancer	20 \| 270
	Asthma	18 \| 349
	Endometriosis	18 \| 535
	non primary Sjogren syndrome sicca	18 \| 840
	hereditary spastic paraplegia	17 \| 313
	Osteoporosis	16 \| 259
	active ulcerative colitis	16 \| 477
	cystic fibrosis and chronic rhinosinusitis	16 \| 213
	sarcoidosis	16 \| 368
	Hypertension	15 \| 293
	glioblastoma multiforme	15 \| 347
	Schizophrenia	14 \| 503
	urothelial carcinoma	14 \| 318
	Prostatic Neoplasms	13 \| 471
	Anemia	12 \| 252
	Autistic Disorder	12 \| 320
	Bipolar Disorder	12 \| 266
	Multiple Sclerosis	12 \| 498
	Neurodegenerative disease	12 \| 383

	Endocrine System	512 \| 18,512
	Female tissues	511 \| 18,647
	Liver and Pancreas	511 \| 18,136
	Nervous System	511 \| 18,561
	Respiratory system	511 \| 17,484
	Blood and immune system	510 \| 17,995
	Cardiovascular System	510 \| 17,958
	Digestive Tract	510 \| 18,473
	Male tissues	510 \| 17,969
	Urinary Tract	510 \| 18,444
	Skin and soft tissues	509 \| 18,115

Development Level

Collection

IMPC Term

Disease

Tissue

Target Family

Jensen-KB Tissue

Drug Target Ontology

Target Development Level

Target Family

PANTHER Protein Ontology

Ligand

GTEx Tissue

HPA RNA Tissue

HPA Protein Tissue

HPM Tissue

JAX/MGI Phenotype

OMIM Phenotype

GWAS Trait

GO Component

UniProt Keywords

Grant Funding IC

Grant Activity

Data Source

	Non-IDG	291 \| 11,969
	Enzyme	118 \| 4,146
	Transcription Factor	39 \| 1,400
	Transporter	22 \| 473
	Kinase	20 \| 634
	Ion Channel	9 \| 341
	Epigenetic	8 \| 242
	GPCR	8 \| 408
	Nuclear Receptor	2 \| 48
	TF/Epigenetic	2 \| 38

	Trachea	519 \| 519
	Brain	7,308 \| 7,308
	Liver	4,988 \| 4,988
	Cervical carcinoma cell	4,915 \| 4,915
	Erythroleukemia cell	4,274 \| 4,274
	Testis	3,862 \| 3,862
	Placenta	3,062 \| 3,062
	T-cell chronic lymphocytic leu...	2,337 \| 2,337
	Lung	2,282 \| 2,282
	Skin	1,548 \| 1,548
	Uterus	1,472 \| 1,472
	Kidney	1,293 \| 1,293
	Colon	1,061 \| 1,061
	Eye	852 \| 852
	Pancreas	828 \| 828
	Muscle	721 \| 721
	Pronephros	715 \| 715
	Cerebellum	693 \| 693
	Ovary	690 \| 690
	Bone marrow	633 \| 633
	Amygdala	622 \| 622
	Spleen	617 \| 617
	Teratocarcinoma cell	600 \| 600
	Heart	582 \| 582
	Blood	570 \| 570
	Colonic cancer cell	562 \| 562
	Lymph	562 \| 562
	Skeletal muscle	543 \| 543
	Blood platelet	539 \| 539
	Hippocampus	528 \| 528
	Tongue	466 \| 466
	Prostate gland epithelium	456 \| 456
	Thymus	425 \| 425
	Mammary gland	415 \| 415
	Uterine cervix	414 \| 414
	Melanoma cell line	363 \| 363
	BTO:0000379	353 \| 353
	Umbilical cord blood	343 \| 343
	Retina	334 \| 334
	Thalamus	330 \| 330
	Small intestine	327 \| 327
	Plasma cell	286 \| 286
	T-lymphocyte	284 \| 284
	B-lymphocyte cell line	273 \| 273
	Hepatoma cell	242 \| 242
	Urinary bladder	226 \| 226
	Breast cancer cell	219 \| 219
	Brain cortex cell line	216 \| 216
	Leukocyte	205 \| 205
	CL-48 cell	198 \| 198
	Interstitial cell of Cajal	193 \| 193
	Neuroblastoma cell	187 \| 187
	Peripheral nervous system	183 \| 183
	Ovary cancer cell	181 \| 181
	Stomach	179 \| 179
	Adrenal gland	176 \| 176
	Cerebral cortex	159 \| 159
	Lymph node	148 \| 148
	Synovium	147 \| 147
	Thyroid gland	144 \| 144
	Keratinocyte	140 \| 140
	Fibroblast	139 \| 139
	Adipose tissue	136 \| 136
	Duodenum	135 \| 135
	Peripheral blood	135 \| 135
	B-cell lymphoma cell	130 \| 130
	Hypophysis	128 \| 128
	Uterine endometrium	122 \| 122
	Hypothalamus	116 \| 116
	Subthalamic nucleus	111 \| 111
	Caudate nucleus	109 \| 109
	Lung cancer cell	104 \| 104
	Prostate cancer cell line	90 \| 90
	Lymphocyte	86 \| 86
	Aorta	84 \| 84
	Retinoblastoma cell	84 \| 84
	Colonic adenocarcinoma cell	81 \| 81
	Monocyte	78 \| 78
	Dendritic cell	76 \| 76
	Lymphoblast	74 \| 74
	Salivary gland	74 \| 74
	Spinal cord	73 \| 73
	Renal cell carcinoma cell	72 \| 72
	Substantia nigra	72 \| 72
	Leukemia cell	69 \| 69
	Corpus callosum	67 \| 67
	Esophagus	65 \| 65
	Lymphoid tissue	60 \| 60
	Scalp	59 \| 59
	Endothelial cell	57 \| 57
	Saliva	56 \| 56
	Hair root	55 \| 55
	Colonic mucosa	54 \| 54
	Lymphoma cell	53 \| 53
	Gastric mucosa	52 \| 52
	Bone	51 \| 51
	Pericardium	50 \| 50
	Prepuce	50 \| 50
	Umbilical vein endothelial cel...	49 \| 49
	Uterine endometrial cancer cel...	49 \| 49