Development Level

Tbio 316 | 10,625
Tdark 121 | 7,003
Tchem 65 | 1,890
Tclin 17 | 602

Collection

Eligible Kinase Proteins 6 | 134
Eligible Ion Channel Proteins 2 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 19 | 633
decreased lean body mass 10 | 195
abnormal behavior 9 | 226
preweaning lethality, incomple... 9 | 260
decreased total body fat amoun... 8 | 186
increased mean corpuscular vol... 7 | 91
decreased body weight 6 | 174
decreased hematocrit 6 | 25
decreased hemoglobin content 6 | 53
abnormal lens morphology 5 | 73
decreased bone mineral content 5 | 157
decreased erythrocyte cell num... 5 | 43
embryonic lethality prior to t... 5 | 187
hypoactivity 5 | 89
abnormal bone structure 4 | 131
decreased bone mineral density 4 | 126
decreased caudal vertebrae num... 4 | 49
decreased circulating glucose ... 4 | 121
decreased circulating serum al... 4 | 79
decreased mean corpuscular hem... 4 | 34
decreased prepulse inhibition 4 | 52
embryonic lethality prior to o... 4 | 148
increased circulating alkaline... 4 | 119
increased circulating creatini... 4 | 29
increased circulating serum al... 4 | 25
increased exploration in new e... 4 | 56
abnormal bone mineralization 3 | 55
abnormal embryo size 3 | 112
abnormal locomotor activation 3 | 26
abnormal retina morphology 3 | 100
abnormal retinal pigmentation 3 | 61
abnormal skin morphology 3 | 23
abnormal spleen morphology 3 | 36
decreased circulating iron lev... 3 | 25
decreased circulating triglyce... 3 | 83
decreased fasted circulating g... 3 | 49
decreased grip strength 3 | 123
decreased heart weight 3 | 44
decreased leukocyte cell numbe... 3 | 54
enlarged heart 3 | 111
increased B cell number 3 | 23
increased blood urea nitrogen ... 3 | 44
increased bone mineral content 3 | 92
increased lean body mass 3 | 107
increased or absent threshold ... 3 | 128
limb grasping 3 | 35
thrombocytosis 3 | 23
abnormal coat/hair pigmentatio... 2 | 54
abnormal eye morphology 2 | 38
abnormal heart morphology 2 | 51
abnormal posture 2 | 5
abnormal rib morphology 2 | 28
abnormal sleep behavior 2 | 63
abnormal startle reflex 2 | 14
abnormal thoracic vertebrae mo... 2 | 16
abnormal vertebral arch morpho... 2 | 9
decreased CD8-positive, alpha-... 2 | 26
decreased T cell number 2 | 31
decreased body length 2 | 108
decreased cervical vertebrae n... 2 | 12
decreased circulating HDL chol... 2 | 77
decreased circulating alkaline... 2 | 41
decreased circulating choleste... 2 | 85
decreased circulating free fat... 2 | 39
decreased circulating glycerol... 2 | 19
decreased circulating phosphat... 2 | 15
decreased circulating thyroxin... 2 | 5
decreased circulating total pr... 2 | 41
decreased granulocyte number 2 | 8
decreased mean corpuscular vol... 2 | 50
decreased mean platelet volume 2 | 12
decreased rib number 2 | 59
decreased startle reflex 2 | 48
enlarged lymph nodes 2 | 27
enlarged urinary bladder 2 | 4
hydrops fetalis 2 | 22
impaired glucose tolerance 2 | 52
increased body length 2 | 20
increased circulating amylase ... 2 | 13
increased circulating calcium ... 2 | 32
increased circulating chloride... 2 | 43
increased circulating phosphat... 2 | 24
increased circulating thyroxin... 2 | 7
increased circulating total pr... 2 | 20
increased grip strength 2 | 83
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 93
increased mean corpuscular hem... 2 | 25
increased rib number 2 | 41
increased sacral vertebrae num... 2 | 62
increased vertical activity 2 | 18
tremors 2 | 34
vertebral fusion 2 | 23
vertebral transformation 2 | 12
abnormal behavioral response t... 1 | 52
abnormal cranium morphology 1 | 32
abnormal tooth morphology 1 | 24
decreased NK cell number 1 | 16

Disease

ovarian cancer 315 | 8,484
osteosarcoma 289 | 7,933
psoriasis 214 | 6,685
medulloblastoma, large-cell 201 | 6,234
glioblastoma 186 | 5,572
lung cancer 159 | 4,466
atypical teratoid / rhabdoid tumor 145 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 139 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 137 | 3,289
Breast cancer 124 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 121 | 2,988
malignant mesothelioma 111 | 3,162
non-small cell lung cancer 111 | 2,798
invasive ductal carcinoma 110 | 2,950
lung adenocarcinoma 104 | 2,713
oligodendroglioma 104 | 2,849
interstitial cystitis 102 | 2,299
lung carcinoma 101 | 2,844
pilocytic astrocytoma 101 | 3,086
pancreatic cancer 97 | 2,300
primitive neuroectodermal tumor 93 | 3,031
pediatric high grade glioma 90 | 2,712
ependymoma 89 | 2,514
astrocytic glioma 84 | 2,241
subependymal giant cell astrocytoma 82 | 2,287
ulcerative colitis 82 | 2,087
pituitary cancer 78 | 1,972
Cancer 76 | 2,346
group 4 medulloblastoma 76 | 1,875
Pick disease 74 | 1,893
Carcinoma 73 | 2,147
pancreatic ductal adenocarcinoma liver metastasis 70 | 1,795
adult high grade glioma 69 | 2,148
ductal carcinoma in situ 69 | 1,745
cystic fibrosis 68 | 1,665
group 3 medulloblastoma 63 | 2,254
juvenile dermatomyositis 60 | 1,189
acute quadriplegic myopathy 58 | 1,157
tuberculosis 58 | 1,557
posterior fossa group B ependymoma 57 | 1,530
spina bifida 54 | 1,064
medulloblastoma 53 | 1,524
adrenocortical carcinoma 52 | 1,427
breast carcinoma 52 | 1,614
nasopharyngeal carcinoma 51 | 1,056
colon cancer 49 | 1,475
diabetes mellitus 49 | 1,663
primary pancreatic ductal adenocarcinoma 49 | 1,271
Multiple myeloma 48 | 1,327
Rheumatoid Arthritis 48 | 1,160
astrocytoma 48 | 1,493
posterior fossa group A ependymoma 44 | 1,511
cutaneous lupus erythematosus 41 | 1,056
sonic hedgehog group medulloblastoma 40 | 1,482
active Crohn's disease 38 | 918
tuberculosis and treatment for 6 months 37 | 686
chronic rhinosinusitis 35 | 512
atypical teratoid/rhabdoid tumor 34 | 1,095
primary Sjogren syndrome 34 | 789
Atopic dermatitis 33 | 944
hepatocellular carcinoma 33 | 532
Waldenstrons macroglobulinemia 32 | 765
aldosterone-producing adenoma 32 | 664
acute myeloid leukemia 31 | 780
dermatomyositis 31 | 933
gastric carcinoma 31 | 832
autosomal dominant Emery-Dreifuss muscular dystrophy 30 | 499
progressive supranuclear palsy 29 | 674
fibroadenoma 26 | 557
pancreatic carcinoma 26 | 567
Down syndrome 25 | 548
esophageal adenocarcinoma 25 | 737
IGA Glomerulonephritis 24 | 454
mucosa-associated lymphoid tissue lymphoma 24 | 480
Alzheimer's disease 23 | 644
Duchenne muscular dystrophy 23 | 602
Obesity 22 | 616
non-small cell lung carcinoma 22 | 413
Intellectual disability 21 | 573
gastric cancer 21 | 430
Amyotrophic Lateral Sclerosis 20 | 431
head and neck cancer 20 | 270
Asthma 18 | 349
Endometriosis 18 | 535
non primary Sjogren syndrome sicca 18 | 840
hereditary spastic paraplegia 17 | 313
Osteoporosis 16 | 257
active ulcerative colitis 16 | 477
cystic fibrosis and chronic rhinosinusitis 16 | 213
sarcoidosis 16 | 358
Hypertension 15 | 287
glioblastoma multiforme 15 | 347
Schizophrenia 14 | 501
urothelial carcinoma 14 | 318
Prostatic Neoplasms 13 | 471
Anemia 12 | 252
Autistic Disorder 12 | 320
Bipolar Disorder 12 | 266
Multiple Sclerosis 12 | 498
Neurodegenerative disease 12 | 383

Tissue

Endocrine System 512 | 18,512
Female tissues 511 | 18,647
Liver and Pancreas 511 | 18,136
Nervous System 511 | 18,561
Respiratory system 511 | 17,484
Blood and immune system 510 | 17,995
Cardiovascular System 510 | 17,958
Digestive Tract 510 | 18,473
Male tissues 510 | 17,969
Urinary Tract 510 | 18,444
Skin and soft tissues 509 | 18,115

Target Family

Non-IDG 291 | 11,971
Enzyme 118 | 4,146
Transcription Factor 39 | 1,400
Transporter 22 | 473
Kinase 20 | 634
Ion Channel 9 | 341
Epigenetic 8 | 242
GPCR 8 | 406
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38

Jensen-KB Tissue

Trachea 519 | 519
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
EGF-like repeat and discoidin I-like domain-containing protein 3 EDIL3 Tbio Non-IDG -1.83671 93.1 157
Monocarboxylate transporter 14 SLC16A14 Tdark Transporter -0.69265 4.88 34
Testis-specific gene 10 protein TSGA10 Tbio Non-IDG -1.05563 13.1 82
Beta-galactoside alpha-2,6-sialyltransferase 1 ST6GAL1 Tchem Enzyme -2.37851 255.2 269
Epidermal growth factor receptor kinase substrate 8 EPS8 Tbio Enzyme -1.80380 77.2 248
Pleckstrin homology domain-containing family G member 7 PLEKHG7 Tdark Non-IDG 0.90 0.13 3
Ankyrin repeat domain-containing protein 26 ANKRD26 Tbio Non-IDG -1.28843 22.9 87
Dimethylaniline monooxygenase [N-oxide-forming] 5 FMO5 Tbio Enzyme -0.93021 9.11 128
Apoptosis inhibitor 5 API5 Tbio Non-IDG -1.32754 23.5 171
Zinc finger protein 493 ZNF493 Tdark Transcription Factor 0.48 0.38 48