Development Level

Tbio 303 | 11,445
Tdark 104 | 6,588
Tchem 51 | 1,598
Tclin 12 | 613

Collection

GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 33 | 979
preweaning lethality, incomple... 12 | 499
decreased body weight 9 | 161
abnormal bone structure 8 | 187
embryonic lethality prior to o... 7 | 239
abnormal behavior 6 | 298
decreased grip strength 6 | 116
embryonic lethality prior to t... 6 | 278
increased startle reflex 6 | 112
abnormal embryo size 5 | 220
abnormal seminal vesicle morph... 5 | 114
enlarged heart 5 | 210
abnormal gait 4 | 69
decreased vertical activity 4 | 208
embryonic growth retardation 4 | 106
hypoactivity 4 | 132
increased heart weight 4 | 62
increased lean body mass 4 | 172
increased monocyte cell number 4 | 63
small superior vagus ganglion 4 | 74
abnormal eye morphology 3 | 68
cataract 3 | 92
decreased blood urea nitrogen ... 3 | 51
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased neutrophil cell numb... 3 | 42
decreased total body fat amoun... 3 | 207
edema 3 | 59
enlarged lymph nodes 3 | 37
hydrometra 3 | 53
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 76
abnormal coat-hair pigmentatio... 2 | 64
abnormal heart morphology 2 | 162
abnormal limb morphology 2 | 13
abnormal nail morphology 2 | 8
abnormal optic disc morphology 2 | 10
abnormal response to new envir... 2 | 10
abnormal retina morphology 2 | 71
abnormal tail morphology 2 | 25
decreased circulating calcium ... 2 | 36
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
hemorrhage 2 | 23
improved glucose tolerance 2 | 79
increased body weight 2 | 25
increased circulating glucose ... 2 | 24
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased mean platelet volume 2 | 45
increased total body fat amoun... 2 | 134
short tibia 2 | 97
tremors 2 | 39
abnormal body wall morphology 1 | 9
abnormal coat appearance 1 | 31
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
brachydactyly 1 | 19
cleft palate 1 | 8
corneal opacity 1 | 32
decreased IgE level 1 | 6
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased mean platelet volume 1 | 25
enlarged epididymis 1 | 31
increased blood urea nitrogen ... 1 | 48
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased vertical activity 1 | 24
long tibia 1 | 25
prenatal lethality 1 | 28
small testis 1 | 58
syndactyly 1 | 23
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 320 | 11,493
ovarian cancer 232 | 8,520
osteosarcoma 215 | 7,950
psoriasis 187 | 6,694
medulloblastoma, large-cell 174 | 6,241
glioblastoma 150 | 5,792
lung cancer 142 | 4,740
atypical teratoid / rhabdoid tumor 127 | 5,112
Breast cancer 118 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 116 | 3,291
ependymoma 114 | 4,679
non-small cell lung cancer 101 | 2,890
pancreatic cancer 98 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 94 | 2,955
malignant mesothelioma 94 | 3,232
invasive ductal carcinoma 91 | 2,951
lung adenocarcinoma 91 | 2,716
Cancer 89 | 2,499
adult high grade glioma 88 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 85 | 2,989
group 3 medulloblastoma 81 | 4,104
interstitial cystitis 79 | 2,312
Astrocytoma, Pilocytic 77 | 3,081
lung carcinoma 76 | 2,843
primitive neuroectodermal tumor 76 | 3,035
Kidney cancer 71 | 2,613
group 4 medulloblastoma 64 | 1,855
pituitary cancer 64 | 1,972
ductal carcinoma in situ 63 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 61 | 1,962
ulcerative colitis 57 | 1,819
astrocytic glioma 56 | 2,597
oligodendroglioma 56 | 2,850
breast carcinoma 54 | 1,638
tuberculosis 54 | 2,010
nasopharyngeal carcinoma 52 | 1,058
cystic fibrosis 51 | 1,696
spina bifida 51 | 1,074
colon cancer 46 | 1,478
Autosomal recessive predisposition 44 | 1,442
diabetes mellitus 42 | 1,728
Atopic dermatitis 41 | 952
subependymal giant cell astrocytoma 41 | 2,287
acute quadriplegic myopathy 40 | 1,158
esophageal adenocarcinoma 40 | 737
Pick disease 39 | 1,894
adrenocortical carcinoma 39 | 1,428
primary pancreatic ductal adenocarcinoma 38 | 1,109
Multiple myeloma 37 | 1,332
active Crohn's disease 37 | 922
astrocytoma 35 | 1,146
juvenile dermatomyositis 35 | 1,187
cutaneous lupus erythematosus 33 | 1,057
Rheumatoid arthritis 31 | 1,191
Schizophrenia 31 | 1,160
pediatric high grade glioma 31 | 1,064
dermatomyositis 30 | 966
Intellectual disability 27 | 1,016
active ulcerative colitis 26 | 764
medulloblastoma 25 | 720
Liver cancer 23 | 604
Obesity 22 | 678
pancreatic carcinoma 22 | 562
Dull intelligence 20 | 645
Endometriosis 20 | 540
Low intelligence 20 | 645
Mental Retardation 20 | 645
Mental deficiency 20 | 645
Poor school performance 20 | 645
aldosterone-producing adenoma 20 | 665
fibroadenoma 20 | 559
gastric carcinoma 20 | 807
non primary Sjogren syndrome sicca 19 | 891
progressive supranuclear palsy 19 | 676
Alzheimer's disease 18 | 658
Amyotrophic lateral sclerosis 18 | 451
Liver Cirrhosis, Experimental 18 | 769
Waldenstrons macroglobulinemia 18 | 765
acute myeloid leukemia 18 | 783
primary Sjogren syndrome 18 | 735
sonic hedgehog group medulloblastoma 18 | 467
Cognitive delay 17 | 608
Global developmental delay 17 | 608
Melanoma 17 | 711
Mental and motor retardation 17 | 608
Prostatic Neoplasms 17 | 495
Short stature 17 | 531
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 510
head and neck cancer 17 | 271
Epilepsy 16 | 792
Seizures 15 | 596
cystic fibrosis and chronic rhinosinusitis 15 | 214
mucosa-associated lymphoid tissue lymphoma 15 | 484
Acquired metabolic disease 14 | 336
Anemia 14 | 365
Cleft Palate 14 | 271
Parkinson's disease 14 | 392
gastric cancer 14 | 459
hepatocellular carcinoma 14 | 547
Duchenne muscular dystrophy 13 | 601

Tissue

Skin and soft tissues 455 | 17,230
Endocrine System 454 | 18,159
Digestive Tract 452 | 17,369
Female tissues 450 | 17,400
Blood and immune system 448 | 16,909
Male tissues 446 | 17,142
Urinary Tract 445 | 16,678
Liver and Pancreas 439 | 16,750
Respiratory system 432 | 16,393
Nervous System 430 | 16,725
Cardiovascular System 422 | 15,192

Target Family

Non-IDG 261 | 12,091
Enzyme 111 | 4,145
Transcription Factor 43 | 1,400
Transporter 16 | 473
Kinase 14 | 634
Epigenetic 9 | 242
oGPCR 7 | 421
Ion Channel 5 | 344
GPCR 2 | 408
Nuclear Receptor 2 | 48

Jensen-KB Tissue

Tongue 470 | 470
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Adenylate kinase 2, mitochondrial AK2 Tbio Kinase -2.00007 98.7 330
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Acidic leucine-rich nuclear phosphoprotein 32 family member E ANP32E Tbio Non-IDG -0.82034 5.60 97
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Epithelial membrane protein 1 EMP1 Tbio Non-IDG -2.60119 387.7 88
Elongation factor G, mitochondrial GFM1 Tbio Non-IDG -2.39993 250.5 121
Integrin beta-like protein 1 ITGBL1 Tbio Non-IDG -0.73415 6.42 83
Ankyrin repeat and SOCS box protein 15 ASB15 Tdark Non-IDG -0.67669 6.19 6
Transcription factor HES-2 HES2 Tdark Transcription Factor -0.19957 1.87 213