Development Level

Tbio 279 | 10,625
Tdark 82 | 7,003
Tchem 53 | 1,890
Tclin 11 | 602

Collection

Eligible non-olfactory GPCR Proteins 3 | 143
Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 21 | 633
abnormal behavior 10 | 226
preweaning lethality, incomple... 9 | 260
abnormal retina morphology 6 | 100
decreased body weight 6 | 174
decreased lean body mass 6 | 195
decreased total body fat amoun... 6 | 186
enlarged spleen 6 | 26
abnormal spleen morphology 5 | 36
decreased circulating insulin ... 5 | 75
embryonic lethality prior to o... 5 | 148
increased fasted circulating g... 5 | 68
decreased grip strength 4 | 123
decreased leukocyte cell numbe... 4 | 54
embryonic lethality prior to t... 4 | 187
increased exploration in new e... 4 | 56
increased hemoglobin content 4 | 45
increased or absent threshold ... 4 | 128
abnormal bone structure 3 | 131
abnormal eye morphology 3 | 38
abnormal lens morphology 3 | 73
decreased body length 3 | 108
decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
decreased caudal vertebrae num... 3 | 49
decreased circulating serum al... 3 | 79
decreased heart weight 3 | 44
decreased lymphocyte cell numb... 3 | 9
decreased startle reflex 3 | 48
enlarged heart 3 | 111
hypoactivity 3 | 89
increased bone mineral content 3 | 92
increased circulating alkaline... 3 | 119
increased circulating iron lev... 3 | 25
limb grasping 3 | 35
abnormal QRS complex 2 | 25
abnormal behavioral response t... 2 | 52
abnormal bone mineralization 2 | 55
abnormal cranium morphology 2 | 32
abnormal digit morphology 2 | 13
abnormal maxilla morphology 2 | 16
abnormal response to tactile s... 2 | 16
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
cardiovascular system phenotyp... 2 | 35
cataract 2 | 26
decreased NK cell number 2 | 16
decreased circulating alkaline... 2 | 41
decreased circulating free fat... 2 | 39
decreased circulating phosphat... 2 | 15
decreased circulating triglyce... 2 | 83
decreased neutrophil cell numb... 2 | 37
hyperactivity 2 | 108
immune system phenotype 2 | 17
improved glucose tolerance 2 | 56
increased blood urea nitrogen ... 2 | 44
increased circulating phosphat... 2 | 24
increased circulating potassiu... 2 | 31
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 93
increased neutrophil cell numb... 2 | 15
increased rib number 2 | 41
increased total body fat amoun... 2 | 57
long tibia 2 | 13
short tibia 2 | 82
abnormal coat appearance 1 | 25
abnormal heart morphology 1 | 51
abnormal locomotor activation 1 | 26
abnormal motor capabilities/co... 1 | 4
abnormal retinal inner nuclear... 1 | 5
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
convulsive seizures 1 | 11
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased blood urea nitrogen ... 1 | 31
decreased circulating sodium l... 1 | 18
decreased vertical activity 1 | 22
female infertility 1 | 34
increased CD4-positive, CD25-p... 1 | 18
increased body length 1 | 20
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased sacral vertebrae num... 1 | 62
prenatal lethality prior to he... 1 | 64
straub tail 1 | 26
tremors 1 | 34
vertebral fusion 1 | 23

Disease

osteosarcoma 226 | 7,933
ovarian cancer 220 | 8,484
psoriasis 156 | 6,685
medulloblastoma, large-cell 147 | 6,234
lung cancer 134 | 4,466
glioblastoma 133 | 5,572
atypical teratoid / rhabdoid tumor 98 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 93 | 3,289
Breast cancer 88 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 82 | 2,988
malignant mesothelioma 82 | 3,162
non-small cell lung cancer 76 | 2,798
Cancer 75 | 2,346
invasive ductal carcinoma 74 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 73 | 2,956
lung carcinoma 72 | 2,844
interstitial cystitis 71 | 2,299
pilocytic astrocytoma 66 | 3,086
lung adenocarcinoma 65 | 2,713
pediatric high grade glioma 65 | 2,712
primitive neuroectodermal tumor 65 | 3,031
oligodendroglioma 63 | 2,849
ependymoma 57 | 2,514
ulcerative colitis 55 | 2,087
Multiple myeloma 54 | 1,327
pancreatic cancer 54 | 2,300
adult high grade glioma 52 | 2,148
group 3 medulloblastoma 51 | 2,254
subependymal giant cell astrocytoma 50 | 2,287
tuberculosis 50 | 1,557
pancreatic ductal adenocarcinoma liver metastasis 48 | 1,795
Pick disease 47 | 1,893
cutaneous lupus erythematosus 45 | 1,056
ductal carcinoma in situ 45 | 1,745
astrocytic glioma 44 | 2,241
breast carcinoma 41 | 1,614
primary Sjogren syndrome 41 | 789
Carcinoma 40 | 2,147
group 4 medulloblastoma 38 | 1,875
colon cancer 37 | 1,475
sonic hedgehog group medulloblastoma 37 | 1,482
Rheumatoid Arthritis 36 | 1,160
medulloblastoma 35 | 1,524
juvenile dermatomyositis 34 | 1,189
pituitary cancer 34 | 1,972
cystic fibrosis 33 | 1,665
acute quadriplegic myopathy 31 | 1,157
astrocytoma 31 | 1,493
diabetes mellitus 31 | 1,663
Atopic dermatitis 30 | 944
adrenocortical carcinoma 30 | 1,427
dermatomyositis 29 | 933
primary pancreatic ductal adenocarcinoma 28 | 1,271
Waldenstrons macroglobulinemia 27 | 765
posterior fossa group A ependymoma 26 | 1,511
posterior fossa group B ependymoma 26 | 1,530
tuberculosis and treatment for 6 months 26 | 686
active Crohn's disease 25 | 918
gastric carcinoma 25 | 832
nasopharyngeal carcinoma 22 | 1,056
acute myeloid leukemia 20 | 780
non primary Sjogren syndrome sicca 19 | 840
Duchenne muscular dystrophy 18 | 602
IGA Glomerulonephritis 18 | 454
hepatocellular carcinoma 18 | 532
sarcoidosis 18 | 358
spina bifida 18 | 1,064
aldosterone-producing adenoma 17 | 664
Down syndrome 16 | 548
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 499
esophageal adenocarcinoma 16 | 737
pancreatic carcinoma 16 | 567
gastric cancer 15 | 430
periodontitis 15 | 269
Endometriosis 14 | 535
Intellectual disability 14 | 573
Multiple Sclerosis 14 | 498
atypical teratoid/rhabdoid tumor 14 | 1,095
Alzheimer's disease 13 | 644
mucosa-associated lymphoid tissue lymphoma 13 | 480
progressive supranuclear palsy 13 | 674
Asthma 12 | 349
Peripheral Neuropathy 12 | 303
tuberculosis and treatment for 3 months 11 | 327
Obesity 10 | 616
Schizophrenia 10 | 501
inflammatory breast cancer 10 | 404
non-small cell lung carcinoma 10 | 413
Amyotrophic Lateral Sclerosis 9 | 431
Epilepsy 9 | 346
Stomach Neoplasms 9 | 282
Vascular disease 9 | 281
hereditary spastic paraplegia 9 | 313
Crohn's disease 8 | 304
Heart disease 8 | 279
Hypersensitivity reaction type II disease 8 | 235
Prostatic Neoplasms 8 | 471
chronic rhinosinusitis 8 | 512
fibroadenoma 8 | 557
head and neck cancer and chronic obstructive pulmonary disease 8 | 237

Tissue

Female tissues 421 | 18,647
Nervous System 421 | 18,561
Digestive Tract 420 | 18,473
Endocrine System 420 | 18,512
Urinary Tract 420 | 18,444
Blood and immune system 419 | 17,995
Liver and Pancreas 418 | 18,136
Male tissues 417 | 17,969
Respiratory system 416 | 17,484
Skin and soft tissues 416 | 18,115
Cardiovascular System 415 | 17,958

Target Family

Non-IDG 247 | 11,971
Enzyme 98 | 4,146
Transcription Factor 34 | 1,400
Kinase 13 | 634
GPCR 10 | 406
Transporter 9 | 473
Ion Channel 6 | 341
Epigenetic 4 | 242
TF/Epigenetic 3 | 38
oGPCR 1 | 421

Jensen-KB Tissue

Thymus 425 | 425
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein THEMIS2 THEMIS2 Tbio Non-IDG -1.15987 17.5 42
Beta-galactoside alpha-2,6-sialyltransferase 1 ST6GAL1 Tchem Enzyme -2.37851 255.2 269
Lymphoid-restricted membrane protein LRMP Tbio Non-IDG -1.17754 15.9 54
Interleukin enhancer-binding factor 2 ILF2 Tbio Non-IDG -1.51960 36.4 249
Sialoadhesin SIGLEC1 Tbio Non-IDG -2.22508 195.6 309
Zinc finger protein 788 ZNF788 Tdark Non-IDG 0.00000 0
Mitochondrial ribonuclease P protein 3 KIAA0391 Tbio Enzyme 66.3 56
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -1.97274 103.1 38
Beta-1-syntrophin SNTB1 Tbio Non-IDG -1.02258 8.71 102
60S ribosomal protein L38 RPL38 Tdark Non-IDG -1.39563 24.2 45