Development Level

Tbio 229 | 11,445
Tdark 49 | 6,588
Tchem 40 | 1,598
Tclin 13 | 613

Collection

Kinase: IDG Consortium (Target... 4 | 125
Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 19 | 979
decreased total body fat amoun... 7 | 207
abnormal behavior 6 | 298
embryonic lethality prior to t... 6 | 278
abnormal embryo size 5 | 220
increased lean body mass 5 | 172
preweaning lethality, incomple... 5 | 499
abnormal coat-hair pigmentatio... 4 | 64
decreased vertical activity 4 | 208
embryonic lethality prior to o... 4 | 239
hyperactivity 4 | 148
male infertility 4 | 123
abnormal lens morphology 3 | 81
abnormal retina morphology 3 | 71
abnormal sleep behavior 3 | 70
cataract 3 | 92
decreased body weight 3 | 161
decreased circulating glucose ... 3 | 126
decreased grip strength 3 | 116
decreased neutrophil cell numb... 3 | 42
embryonic growth retardation 3 | 106
enlarged heart 3 | 210
increased bone mineral content 3 | 108
increased caudal vertebrae num... 3 | 7
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal retinal blood vessel ... 2 | 26
decreased circulating choleste... 2 | 93
decreased circulating free fat... 2 | 31
decreased erythrocyte cell num... 2 | 62
decreased exploration in new e... 2 | 11
decreased fasted circulating g... 2 | 65
decreased lymphocyte cell numb... 2 | 83
decreased startle reflex 2 | 75
enlarged epididymis 2 | 31
enlarged spleen 2 | 41
female infertility 2 | 60
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating glucose ... 2 | 24
increased circulating potassiu... 2 | 29
increased circulating total pr... 2 | 28
increased erythrocyte cell num... 2 | 39
increased grip strength 2 | 41
increased heart rate 2 | 23
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased mean corpuscular vol... 2 | 92
increased neutrophil cell numb... 2 | 46
small superior vagus ganglion 2 | 74
small testis 2 | 58
thrombocytosis 2 | 27
abnormal body wall morphology 1 | 9
abnormal embryo turning 1 | 31
abnormal optic disc morphology 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased hematocrit 1 | 46
decreased total retina thickne... 1 | 17
decreased urine magnesium leve... 1 | 3
edema 1 | 59
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
limb grasping 1 | 41
long tibia 1 | 25
shortened RR interval 1 | 17
small kidney 1 | 16

Disease

Carcinoma 217 | 11,493
ovarian cancer 187 | 8,520
medulloblastoma, large-cell 166 | 6,241
osteosarcoma 156 | 7,950
glioblastoma 147 | 5,792
atypical teratoid / rhabdoid tumor 141 | 5,112
ependymoma 125 | 4,679
psoriasis 121 | 6,694
group 3 medulloblastoma 105 | 4,104
adult high grade glioma 100 | 3,801
Astrocytoma, Pilocytic 96 | 3,081
lung cancer 96 | 4,740
primitive neuroectodermal tumor 92 | 3,035
oligodendroglioma 88 | 2,850
astrocytic glioma 82 | 2,597
lung carcinoma 77 | 2,843
malignant mesothelioma 76 | 3,232
Breast cancer 75 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 68 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 65 | 2,955
subependymal giant cell astrocytoma 65 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 63 | 2,989
non-small cell lung cancer 62 | 2,890
Pick disease 61 | 1,894
pancreatic cancer 61 | 2,398
invasive ductal carcinoma 57 | 2,951
lung adenocarcinoma 56 | 2,716
Kidney cancer 49 | 2,613
Cancer 46 | 2,499
pituitary cancer 46 | 1,972
tuberculosis 44 | 2,010
pancreatic ductal adenocarcinoma liver metastasis 42 | 1,962
interstitial cystitis 40 | 2,312
ulcerative colitis 39 | 1,819
adrenocortical carcinoma 38 | 1,428
group 4 medulloblastoma 38 | 1,855
cystic fibrosis 36 | 1,696
colon cancer 33 | 1,478
astrocytoma 31 | 1,146
Multiple myeloma 30 | 1,332
breast carcinoma 30 | 1,638
Autosomal recessive predisposition 29 | 1,442
Schizophrenia 28 | 1,160
ductal carcinoma in situ 28 | 1,745
pediatric high grade glioma 27 | 1,064
diabetes mellitus 26 | 1,728
primary pancreatic ductal adenocarcinoma 26 | 1,109
Rheumatoid arthritis 25 | 1,191
acute quadriplegic myopathy 22 | 1,158
juvenile dermatomyositis 22 | 1,187
spina bifida 22 | 1,074
Bipolar Disorder 21 | 666
Epilepsy 21 | 792
active Crohn's disease 21 | 922
cutaneous lupus erythematosus 21 | 1,057
dermatomyositis 21 | 966
Down syndrome 20 | 499
pancreatic carcinoma 20 | 562
progressive supranuclear palsy 20 | 676
aldosterone-producing adenoma 19 | 665
non primary Sjogren syndrome sicca 19 | 891
Alzheimer's disease 18 | 658
Parkinson's disease 18 | 392
Obesity 17 | 678
Waldenstrons macroglobulinemia 17 | 765
active ulcerative colitis 17 | 764
gastric cancer 17 | 459
primary Sjogren syndrome 17 | 735
Prostatic Neoplasms 16 | 495
acute myeloid leukemia 16 | 783
esophageal adenocarcinoma 16 | 737
medulloblastoma 16 | 720
nasopharyngeal carcinoma 16 | 1,058
Duchenne muscular dystrophy 15 | 601
Neurodegenerative disease 15 | 414
Seizures 14 | 596
gastric carcinoma 14 | 807
hepatocellular carcinoma 14 | 547
Atopic dermatitis 13 | 952
Depressive disorder 13 | 409
Liver Cirrhosis, Experimental 13 | 769
hereditary spastic paraplegia 13 | 318
sonic hedgehog group medulloblastoma 13 | 467
Intellectual disability 12 | 1,016
Melanoma 12 | 711
Mental Depression 12 | 333
Alcoholic Intoxication, Chronic 11 | 289
Liver cancer 11 | 604
Major Depressive Disorder 11 | 301
Multiple Sclerosis 11 | 540
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
chronic rhinosinusitis 11 | 512
fibroadenoma 11 | 559
posterior fossa group B ependymoma 11 | 416
Acquired metabolic disease 10 | 336
Amyotrophic lateral sclerosis 10 | 451
Muscle hypotonia 10 | 571
Unipolar Depression 10 | 250
nephrosclerosis 10 | 333
tuberculosis and treatment for 6 months 10 | 409

Tissue

Endocrine System 327 | 18,159
Female tissues 323 | 17,400
Nervous System 323 | 16,725
Digestive Tract 321 | 17,369
Male tissues 321 | 17,142
Skin and soft tissues 321 | 17,230
Liver and Pancreas 318 | 16,750
Urinary Tract 316 | 16,678
Blood and immune system 315 | 16,909
Respiratory system 313 | 16,393
Cardiovascular System 305 | 15,192

Target Family

Non-IDG 171 | 12,091
Enzyme 94 | 4,145
Transcription Factor 22 | 1,400
Transporter 19 | 473
Kinase 12 | 634
GPCR 6 | 408
Ion Channel 6 | 344
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Thalamus 331 | 331
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Sorting nexin-10 SNX10 Tbio Non-IDG -1.13183 16.8 72
GRB2-associated-binding protein 3 GAB3 Tbio Non-IDG -0.78182 5.77 104
Iron-sulfur cluster assembly 1 homolog, mitochondrial ISCA1 Tbio Non-IDG -1.68100 45.7 44
3-hydroxybutyrate dehydrogenase type 2 BDH2 Tbio Enzyme -1.15003 15.8 112
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase ADI1 Tbio Enzyme -2.05198 103.3 194
2-oxoglutarate dehydrogenase-like, mitochondrial OGDHL Tbio Enzyme -0.59292 3.63 46
Galactocerebrosidase GALC Tbio Enzyme -2.56924 363.2 143
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
Protein FAM118A FAM118A Tdark Non-IDG -0.04589 1.09 32