Development Level

Tbio 362 | 10,625
Tdark 199 | 7,003
Tchem 35 | 1,890
Tclin 4 | 602

Collection

Eligible Kinase Proteins 4 | 134
Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 23 | 633
preweaning lethality, incomple... 12 | 260
abnormal behavior 10 | 226
decreased body weight 7 | 174
decreased total body fat amoun... 7 | 186
embryonic lethality prior to t... 7 | 187
decreased grip strength 6 | 123
embryonic lethality prior to o... 6 | 148
increased lean body mass 6 | 107
increased or absent threshold ... 6 | 128
abnormal bone mineralization 5 | 55
abnormal embryo size 5 | 112
abnormal spleen morphology 5 | 36
decreased bone mineral content 5 | 157
decreased lean body mass 5 | 195
decreased prepulse inhibition 5 | 52
decreased rib number 5 | 59
hyperactivity 5 | 108
hypoactivity 5 | 89
male infertility 5 | 62
abnormal retina morphology 4 | 100
increased grip strength 4 | 83
increased mean corpuscular hem... 4 | 93
prenatal lethality prior to he... 4 | 64
short tibia 4 | 82
abnormal cranium morphology 3 | 32
abnormal lens morphology 3 | 73
decreased NK cell number 3 | 16
decreased bone mineral density 3 | 126
decreased caudal vertebrae num... 3 | 49
decreased circulating choleste... 3 | 85
decreased circulating serum al... 3 | 79
decreased heart weight 3 | 44
decreased hemoglobin content 3 | 53
decreased leukocyte cell numbe... 3 | 54
enlarged heart 3 | 111
enlarged spleen 3 | 26
increased circulating alkaline... 3 | 119
increased exploration in new e... 3 | 56
increased fasted circulating g... 3 | 68
increased hemoglobin content 3 | 45
increased mean corpuscular hem... 3 | 25
increased mean corpuscular vol... 3 | 91
abnormal bone structure 2 | 131
abnormal coat/hair pigmentatio... 2 | 54
abnormal eye morphology 2 | 38
abnormal femur morphology 2 | 14
abnormal iris morphology 2 | 12
abnormal locomotor activation 2 | 26
abnormal rib morphology 2 | 28
abnormal seminal vesicle morph... 2 | 47
abnormal skin condition 2 | 6
abnormal skin morphology 2 | 23
abnormal sleep behavior 2 | 63
abnormal snout morphology 2 | 18
abnormal vocalization 2 | 21
cardiovascular system phenotyp... 2 | 35
cataract 2 | 26
corneal opacity 2 | 25
decreased NK T cell number 2 | 28
decreased blood urea nitrogen ... 2 | 31
decreased circulating amylase ... 2 | 24
decreased circulating glucose ... 2 | 121
decreased circulating insulin ... 2 | 75
decreased lumbar vertebrae num... 2 | 62
decreased mature B cell number 2 | 25
decreased mean corpuscular vol... 2 | 50
decreased red blood cell distr... 2 | 11
decreased startle reflex 2 | 48
decreased vertical activity 2 | 22
improved glucose tolerance 2 | 56
increased body weight 2 | 42
increased bone mineral content 2 | 92
increased bone mineral density 2 | 52
increased circulating aspartat... 2 | 17
increased circulating choleste... 2 | 53
increased erythrocyte cell num... 2 | 26
increased heart rate 2 | 17
increased neutrophil cell numb... 2 | 15
increased respiratory quotient 2 | 12
increased startle reflex 2 | 38
shortened RR interval 2 | 19
small testis 2 | 37
thrombocytopenia 2 | 46
thrombocytosis 2 | 23
abnormal heart morphology 1 | 51
abnormal neural tube closure 1 | 37
abnormal retinal pigmentation 1 | 61
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
absent pinna reflex 1 | 21
decreased cervical vertebrae n... 1 | 12
decreased circulating magnesiu... 1 | 11
decreased eosinophil cell numb... 1 | 41
decreased mean corpuscular hem... 1 | 34
embryonic growth retardation 1 | 28
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased mean platelet volume 1 | 19
prenatal lethality 1 | 16

Disease

ovarian cancer 356 | 8,484
osteosarcoma 307 | 7,933
glioblastoma 231 | 5,572
medulloblastoma, large-cell 221 | 6,234
psoriasis 188 | 6,685
atypical teratoid / rhabdoid tumor 169 | 4,369
lung cancer 153 | 4,466
primitive neuroectodermal tumor 139 | 3,031
Breast cancer 132 | 3,094
intraductal papillary-mucinous neoplasm (IPMN) 116 | 3,289
malignant mesothelioma 112 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 111 | 2,988
pediatric high grade glioma 111 | 2,712
ependymoma 108 | 2,514
oligodendroglioma 102 | 2,849
invasive ductal carcinoma 101 | 2,950
group 3 medulloblastoma 99 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 98 | 2,956
non-small cell lung cancer 96 | 2,798
astrocytic glioma 95 | 2,241
lung adenocarcinoma 90 | 2,713
pilocytic astrocytoma 89 | 3,086
Pick disease 84 | 1,893
lung carcinoma 76 | 2,844
subependymal giant cell astrocytoma 75 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 74 | 1,795
Carcinoma 72 | 2,147
pancreatic cancer 71 | 2,300
group 4 medulloblastoma 68 | 1,875
adult high grade glioma 67 | 2,148
ulcerative colitis 66 | 2,087
ductal carcinoma in situ 63 | 1,745
breast carcinoma 59 | 1,614
adrenocortical carcinoma 57 | 1,427
pituitary cancer 57 | 1,972
interstitial cystitis 54 | 2,299
posterior fossa group B ependymoma 54 | 1,530
sonic hedgehog group medulloblastoma 53 | 1,482
Cancer 50 | 2,346
cystic fibrosis 50 | 1,665
juvenile dermatomyositis 50 | 1,189
atypical teratoid/rhabdoid tumor 49 | 1,095
Multiple myeloma 46 | 1,327
astrocytoma 46 | 1,493
medulloblastoma 46 | 1,524
colon cancer 45 | 1,475
primary pancreatic ductal adenocarcinoma 43 | 1,271
posterior fossa group A ependymoma 39 | 1,511
tuberculosis 38 | 1,557
tuberculosis and treatment for 6 months 38 | 686
acute quadriplegic myopathy 35 | 1,157
progressive supranuclear palsy 35 | 674
spina bifida 34 | 1,064
Intellectual disability 33 | 573
non primary Sjogren syndrome sicca 33 | 840
dermatomyositis 31 | 933
Rheumatoid Arthritis 30 | 1,160
active Crohn's disease 30 | 918
diabetes mellitus 29 | 1,663
nasopharyngeal carcinoma 28 | 1,056
Atopic dermatitis 27 | 944
acute myeloid leukemia 27 | 780
Waldenstrons macroglobulinemia 26 | 765
IGA Glomerulonephritis 25 | 454
primary Sjogren syndrome 25 | 789
hepatocellular carcinoma 23 | 532
aldosterone-producing adenoma 22 | 664
pancreatic carcinoma 22 | 567
Neurodegenerative disease 21 | 383
cutaneous lupus erythematosus 20 | 1,056
gastric carcinoma 20 | 832
Duchenne muscular dystrophy 19 | 602
esophageal adenocarcinoma 19 | 737
fibroadenoma 17 | 557
Alzheimer's disease 16 | 644
chronic rhinosinusitis 16 | 512
gastric cancer 16 | 430
interstitial lung disease 16 | 291
Down syndrome 15 | 548
Epilepsy 15 | 346
Polycystic Ovary Syndrome 15 | 332
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 499
Chronic Lymphocytic Leukemia 12 | 242
Endometriosis 12 | 535
Obesity 12 | 616
Schizophrenia 12 | 501
hereditary spastic paraplegia 12 | 313
sarcoidosis 11 | 358
Acquired metabolic disease 10 | 267
Autistic Disorder 10 | 320
Mammary Neoplasms 10 | 410
Peripheral Neuropathy 10 | 303
Stomach Neoplasms 10 | 282
active ulcerative colitis 10 | 477
inflammatory breast cancer 10 | 404
non-inflammatory breast cancer 10 | 208
Amyotrophic Lateral Sclerosis 9 | 431
Craniofacial Abnormalities 9 | 147
Kidney disease 9 | 396
Microcephaly 9 | 149

Tissue

Blood and immune system 590 | 17,995
Female tissues 589 | 18,647
Nervous System 589 | 18,561
Digestive Tract 588 | 18,473
Endocrine System 588 | 18,512
Male tissues 588 | 17,969
Cardiovascular System 587 | 17,958
Urinary Tract 587 | 18,444
Liver and Pancreas 585 | 18,136
Respiratory system 583 | 17,484
Skin and soft tissues 581 | 18,115

Target Family

Non-IDG 342 | 11,971
Enzyme 152 | 4,146
Transcription Factor 55 | 1,400
Transporter 18 | 473
Kinase 14 | 634
Epigenetic 12 | 242
TF/Epigenetic 3 | 38
GPCR 2 | 406
Ion Channel 2 | 341

Jensen-KB Tissue

Teratocarcinoma cell 600 | 600
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Equilibrative nucleoside transporter 4 SLC29A4 Tbio Transporter -1.79381 73.1 189
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Nuclear autoantigenic sperm protein NASP Tbio Non-IDG -1.72078 58.3 103
Exocyst complex component 7 EXOC7 Tbio Non-IDG -1.72231 55.8 158
Transmembrane protease serine 7 TMPRSS7 Tdark Enzyme 0.24 0.97 63
Protein C21orf2 C21orf2 Tbio Non-IDG -1.66840 37.4 95
Protein Niban FAM129A Tbio Non-IDG -1.03213 12.4 149
U3 small nucleolar RNA-interacting protein 2 RRP9 Tbio Non-IDG -0.95790 8.59 56
Emerin EMD Tbio Non-IDG -2.77469 617.6 238
MAP7 domain-containing protein 3 MAP7D3 Tbio Non-IDG -0.92082 8.05 8