Development Level

Tbio 184 | 10,625
Tchem 58 | 1,890
Tdark 30 | 7,003
Tclin 12 | 602

IMPC Term

preweaning lethality, complete... 13 | 633
abnormal behavior 6 | 226
embryonic lethality prior to o... 5 | 148
embryonic lethality prior to t... 5 | 187
preweaning lethality, incomple... 5 | 260
decreased bone mineral content 3 | 157
decreased caudal vertebrae num... 3 | 49
decreased circulating free fat... 3 | 39
decreased circulating glucose ... 3 | 121
decreased circulating triglyce... 3 | 83
decreased lean body mass 3 | 195
decreased total body fat amoun... 3 | 186
increased bone mineral content 3 | 92
increased circulating alkaline... 3 | 119
increased grip strength 3 | 83
increased hemoglobin content 3 | 45
abnormal embryo size 2 | 112
abnormal kidney morphology 2 | 30
abnormal neural tube closure 2 | 37
decreased body weight 2 | 174
decreased circulating HDL chol... 2 | 77
decreased effector memory CD8-... 2 | 24
decreased eosinophil cell numb... 2 | 41
decreased erythrocyte cell num... 2 | 43
decreased hematocrit 2 | 25
decreased hemoglobin content 2 | 53
decreased lymphocyte cell numb... 2 | 9
decreased neutrophil cell numb... 2 | 37
enlarged heart 2 | 111
improved glucose tolerance 2 | 56
increased blood uric acid leve... 2 | 5
increased granulocyte number 2 | 8
increased mean corpuscular hem... 2 | 93
increased or absent threshold ... 2 | 128
abnormal body wall morphology 1 | 7
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal esophagus morphology 1 | 4
abnormal facial morphology 1 | 9
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal sleep behavior 1 | 63
abnormal snout morphology 1 | 18
cataract 1 | 26
cleft palate 1 | 6
cyanosis 1 | 6
decreased CD4-positive, CD25-p... 1 | 24
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased basophil cell number 1 | 11
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating iron lev... 1 | 25
decreased circulating phosphat... 1 | 15
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
embryonic growth retardation 1 | 28
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
hemorrhage 1 | 12
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
increased B cell number 1 | 23
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased rib number 1 | 41
increased startle reflex 1 | 38
increased vertical activity 1 | 18
oligodactyly 1 | 14
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
small superior vagus ganglion 1 | 20
straub tail 1 | 26
thrombocytopenia 1 | 46
thrombocytosis 1 | 23
tremors 1 | 34

Disease

ovarian cancer 181 | 8,484
osteosarcoma 165 | 7,933
psoriasis 132 | 6,685
medulloblastoma, large-cell 117 | 6,234
lung cancer 113 | 4,466
glioblastoma 110 | 5,572
Cancer 101 | 2,346
atypical teratoid / rhabdoid tumor 73 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 71 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 66 | 2,988
invasive ductal carcinoma 64 | 2,950
malignant mesothelioma 62 | 3,162
non-small cell lung cancer 62 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 60 | 2,956
pediatric high grade glioma 60 | 2,712
oligodendroglioma 58 | 2,849
pilocytic astrocytoma 57 | 3,086
ulcerative colitis 57 | 2,087
primitive neuroectodermal tumor 55 | 3,031
Breast cancer 54 | 3,094
Multiple myeloma 52 | 1,327
interstitial cystitis 51 | 2,299
lung carcinoma 51 | 2,844
Waldenstrons macroglobulinemia 50 | 765
pancreatic cancer 48 | 2,300
subependymal giant cell astrocytoma 48 | 2,287
lung adenocarcinoma 47 | 2,713
astrocytoma 45 | 1,493
Rheumatoid Arthritis 44 | 1,160
group 3 medulloblastoma 42 | 2,254
astrocytic glioma 41 | 2,241
dermatomyositis 41 | 933
ependymoma 41 | 2,514
juvenile dermatomyositis 41 | 1,189
tuberculosis 41 | 1,557
Pick disease 40 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 40 | 1,795
primary Sjogren syndrome 40 | 789
cutaneous lupus erythematosus 38 | 1,056
Carcinoma 37 | 2,147
acute quadriplegic myopathy 37 | 1,157
diabetes mellitus 36 | 1,663
group 4 medulloblastoma 35 | 1,875
adult high grade glioma 32 | 2,148
posterior fossa group A ependymoma 32 | 1,511
ductal carcinoma in situ 29 | 1,745
atypical teratoid/rhabdoid tumor 27 | 1,095
colon cancer 27 | 1,475
medulloblastoma 27 | 1,524
adrenocortical carcinoma 26 | 1,427
cystic fibrosis 26 | 1,665
breast carcinoma 25 | 1,614
primary pancreatic ductal adenocarcinoma 25 | 1,271
acute myeloid leukemia 24 | 780
sonic hedgehog group medulloblastoma 24 | 1,482
pituitary cancer 21 | 1,972
Alzheimer's disease 20 | 644
IGA Glomerulonephritis 19 | 454
tuberculosis and treatment for 6 months 19 | 686
Atopic dermatitis 18 | 944
Duchenne muscular dystrophy 18 | 602
gastric carcinoma 18 | 832
nasopharyngeal carcinoma 18 | 1,056
non primary Sjogren syndrome sicca 18 | 840
posterior fossa group B ependymoma 18 | 1,530
progressive supranuclear palsy 18 | 674
Down syndrome 16 | 548
active Crohn's disease 16 | 918
spina bifida 16 | 1,064
Arthritis 15 | 248
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 499
Asthma 14 | 349
Mammary Neoplasms 14 | 410
Vascular disease 14 | 281
pancreatic carcinoma 14 | 567
aldosterone-producing adenoma 13 | 664
esophageal adenocarcinoma 13 | 737
hepatocellular carcinoma 13 | 532
Multiple Sclerosis 12 | 498
Amyotrophic Lateral Sclerosis 11 | 431
Crohn's disease 11 | 304
Endometriosis 11 | 535
Hypersensitivity reaction type II disease 11 | 235
Intellectual disability 11 | 573
gastric cancer 11 | 430
Kidney disease 10 | 396
interstitial lung disease 10 | 291
periodontitis 10 | 269
Chronic Lymphocytic Leukemia 9 | 242
Inflammatory bowel disease 9 | 142
Neurodegenerative disease 9 | 383
sarcoidosis 9 | 358
HIV Infections 8 | 100
Lung disease 8 | 132
Prostatic Neoplasms 8 | 471
Stomach Neoplasms 8 | 282
chronic lymphosyte leukemia 8 | 232
chronic rhinosinusitis 8 | 512
fibroadenoma 8 | 557
hereditary spastic paraplegia 8 | 313

Tissue

Blood and immune system 277 | 17,995
Female tissues 277 | 18,647
Urinary Tract 277 | 18,444
Digestive Tract 276 | 18,473
Nervous System 276 | 18,561
Cardiovascular System 275 | 17,958
Endocrine System 275 | 18,512
Liver and Pancreas 275 | 18,136
Respiratory system 274 | 17,484
Skin and soft tissues 274 | 18,115
Male tissues 273 | 17,969

Target Family

Non-IDG 188 | 11,971
Enzyme 44 | 4,146
Kinase 18 | 634
Transcription Factor 17 | 1,400
Epigenetic 10 | 242
GPCR 2 | 406
Ion Channel 2 | 341
TF/Epigenetic 2 | 38
Transporter 1 | 473

Jensen-KB Tissue

T-lymphocyte 284 | 284
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methyl-CpG-binding protein 2 MECP2 Tchem Transcription Factor -3.22710 1827.6 567
Malate dehydrogenase, cytoplasmic MDH1 Tbio Enzyme -2.61325 409.6 244
F-actin-capping protein subunit alpha-1 CAPZA1 Tbio Non-IDG -1.28182 20.1 139
Interleukin enhancer-binding factor 3 ILF3 Tbio Non-IDG -2.09543 135.8 239
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.85843 68.9 516
Mitochondrial ribonuclease P protein 3 KIAA0391 Tbio Enzyme 66.3 56
Neuroblast differentiation-associated protein AHNAK AHNAK Tbio Non-IDG -1.61845 51.3 82
Actin-related protein 3 ACTR3 Tbio Non-IDG -1.25542 16.8 169
Interleukin-1 receptor type 1 IL1R1 Tclin Non-IDG -2.63413 362.9 482
Bromodomain-containing protein 2 BRD2 Tchem Epigenetic -2.42927 0.00000 306