Development Level

Tbio 201 | 11,651
Tchem 49 | 1,388
Tdark 24 | 6,593
Tclin 12 | 612

Collection

Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 26 | 979
preweaning lethality, incomple... 12 | 499
abnormal behavior 6 | 298
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 5 | 278
decreased circulating triglyce... 4 | 79
decreased vertical activity 4 | 208
cataract 3 | 92
decreased circulating HDL chol... 3 | 68
decreased erythrocyte cell num... 3 | 62
decreased startle reflex 3 | 75
decreased total body fat amoun... 3 | 207
improved glucose tolerance 3 | 79
increased hemoglobin content 3 | 45
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
increased or absent threshold ... 3 | 101
thrombocytopenia 3 | 56
abnormal embryo size 2 | 220
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal sleep behavior 2 | 70
abnormal snout morphology 2 | 23
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased heart left ventricle... 2 | 28
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
enlarged spleen 2 | 41
hemorrhage 2 | 23
increased blood uric acid leve... 2 | 5
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
increased grip strength 2 | 41
increased mean corpuscular hem... 2 | 96
increased startle reflex 2 | 112
short tibia 2 | 97
small superior vagus ganglion 2 | 74
abnormal body wall morphology 1 | 9
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal esophagus morphology 1 | 5
abnormal gait 1 | 69
abnormal limb bud morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
cleft palate 1 | 8
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
microphthalmia 1 | 26
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small testis 1 | 58
small thymus 1 | 16
syndactyly 1 | 23
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 197 | 11,493
ovarian cancer 182 | 8,520
osteosarcoma 166 | 7,950
psoriasis 131 | 6,694
lung cancer 117 | 4,740
glioblastoma 116 | 5,792
medulloblastoma, large-cell 116 | 6,241
Cancer 105 | 2,499
atypical teratoid / rhabdoid tumor 91 | 5,112
ependymoma 79 | 4,679
group 3 medulloblastoma 79 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 71 | 3,291
adult high grade glioma 67 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 66 | 2,989
invasive ductal carcinoma 64 | 2,951
malignant mesothelioma 64 | 3,232
non-small cell lung cancer 62 | 2,890
Breast cancer 60 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 60 | 2,955
Kidney cancer 58 | 2,613
oligodendroglioma 58 | 2,850
Astrocytoma, Pilocytic 57 | 3,081
primitive neuroectodermal tumor 55 | 3,035
interstitial cystitis 52 | 2,312
ulcerative colitis 52 | 1,819
Multiple myeloma 51 | 1,332
lung carcinoma 51 | 2,843
Waldenstrons macroglobulinemia 50 | 765
pancreatic cancer 50 | 2,398
tuberculosis 50 | 2,010
astrocytic glioma 49 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 48 | 1,962
subependymal giant cell astrocytoma 48 | 2,287
lung adenocarcinoma 47 | 2,716
Rheumatoid arthritis 43 | 1,191
dermatomyositis 41 | 966
juvenile dermatomyositis 41 | 1,187
Pick disease 40 | 1,894
astrocytoma 38 | 1,146
cutaneous lupus erythematosus 38 | 1,057
acute quadriplegic myopathy 37 | 1,158
diabetes mellitus 37 | 1,728
primary Sjogren syndrome 36 | 735
group 4 medulloblastoma 30 | 1,855
Autosomal recessive predisposition 29 | 1,442
Liver Cirrhosis, Experimental 29 | 769
ductal carcinoma in situ 29 | 1,745
cystic fibrosis 28 | 1,696
colon cancer 27 | 1,478
adrenocortical carcinoma 26 | 1,428
breast carcinoma 26 | 1,638
Schizophrenia 25 | 1,160
acute myeloid leukemia 25 | 783
pediatric high grade glioma 25 | 1,064
non primary Sjogren syndrome sicca 22 | 891
Alzheimer's disease 21 | 658
pituitary cancer 21 | 1,972
nasopharyngeal carcinoma 19 | 1,058
Atopic dermatitis 18 | 952
Duchenne muscular dystrophy 18 | 601
gastric carcinoma 18 | 807
primary pancreatic ductal adenocarcinoma 18 | 1,109
progressive supranuclear palsy 18 | 676
Asthma 16 | 385
Down syndrome 16 | 499
active Crohn's disease 16 | 922
spina bifida 16 | 1,074
Arthritis 15 | 290
Breast Neoplasms 15 | 445
Intellectual disability 15 | 1,016
Short stature 15 | 531
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 510
hepatocellular carcinoma 15 | 547
Mammary Neoplasms 14 | 425
Multiple Sclerosis 14 | 540
Vascular disease 14 | 319
aldosterone-producing adenoma 14 | 665
pancreatic carcinoma 14 | 562
Dull intelligence 13 | 645
Hypersensitivity reaction type II disease 13 | 253
Liver cancer 13 | 604
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645
esophageal adenocarcinoma 13 | 737
Amyotrophic lateral sclerosis 12 | 451
Bipolar Disorder 12 | 666
Cognitive delay 12 | 608
Endometriosis 12 | 540
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
Arthritis, Rheumatoid 11 | 174
Crohn's disease 11 | 321
gastric cancer 11 | 459
medulloblastoma 11 | 720
periodontitis 11 | 293
Epilepsy 10 | 792
Kidney disease 10 | 430
Melanoma 10 | 711

Tissue

Digestive Tract 278 | 17,369
Skin and soft tissues 278 | 17,230
Liver and Pancreas 277 | 16,750
Blood and immune system 276 | 16,909
Endocrine System 276 | 18,159
Female tissues 276 | 17,400
Male tissues 276 | 17,142
Urinary Tract 273 | 16,678
Respiratory system 272 | 16,393
Cardiovascular System 268 | 15,192
Nervous System 266 | 16,725

Target Family

Non-IDG 190 | 12,091
Enzyme 44 | 4,145
Kinase 18 | 634
Transcription Factor 17 | 1,400
Epigenetic 10 | 242
GPCR 2 | 408
Ion Channel 2 | 344
TF/Epigenetic 2 | 38
Transporter 1 | 473

Jensen-KB Tissue

T-lymphocyte 286 | 286
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAP kinase-interacting serine/threonine-protein kinase 1 MKNK1 Tchem Kinase -1.71576 46.7 408
Lamina-associated polypeptide 2, isoform alpha TMPO Tbio Non-IDG -2.11834 246.0 283
Lamina-associated polypeptide 2, isoforms beta/gamma TMPO Tbio Non-IDG -2.11834 246.0 283
Epsin-1 EPN1 Tbio Non-IDG -1.52389 32.5 163
THUMP domain-containing protein 1 THUMPD1 Tbio Non-IDG -2.79570 617.3 85
Integrin beta-7 ITGB7 Tclin Non-IDG -1.63572 38.4 374
Tumor necrosis factor receptor superfamily member 18 TNFRSF18 Tbio Non-IDG -2.34111 233.7 604
Ras-specific guanine nucleotide-releasing factor RalGPS2 RALGPS2 Tdark Non-IDG -0.16734 2.43 84
Vasoactive intestinal polypeptide receptor 2 VIPR2 Tchem GPCR -2.20668 142.1 255
CCAAT/enhancer-binding protein gamma CEBPG Tbio Transcription Factor -0.92558 8.45 248