Development Level

Tbio 105 | 11,445
Tchem 23 | 1,598
Tdark 15 | 6,588
Tclin 5 | 613

Collection

GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 6 | 499
abnormal behavior 5 | 298
abnormal bone mineralization 3 | 38
abnormal embryo size 3 | 220
abnormal eye morphology 3 | 68
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
decreased T cell number 2 | 15
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased circulating creatini... 2 | 39
decreased heart weight 2 | 27
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
embryonic growth retardation 2 | 106
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating aspartat... 2 | 15
increased circulating chloride... 2 | 41
increased leukocyte cell numbe... 2 | 47
small spleen 2 | 19
abnormal QT variability 1 | 10
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal neural tube closure 1 | 46
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal tail movements 1 | 12
anophthalmia 1 | 33
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased kidney weight 1 | 1
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased B cell number 1 | 9
increased CD4-positive, alpha ... 1 | 4
increased T cell number 1 | 6
increased bone mineral content 1 | 108
increased circulating bilirubi... 1 | 16
increased circulating creatine... 1 | 5
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
macrophthalmia 1 | 2
mammalian phenotype 1 | 17
persistence of hyaloid vascula... 1 | 33
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
small adrenal glands 1 | 16
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 97 | 11,493
ovarian cancer 81 | 8,520
osteosarcoma 77 | 7,950
psoriasis 66 | 6,694
glioblastoma 60 | 5,792
lung cancer 58 | 4,740
atypical teratoid / rhabdoid tumor 47 | 5,112
medulloblastoma, large-cell 47 | 6,241
Astrocytoma, Pilocytic 38 | 3,081
invasive ductal carcinoma 38 | 2,951
ependymoma 37 | 4,679
lung carcinoma 37 | 2,843
malignant mesothelioma 37 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
adult high grade glioma 33 | 3,801
Cancer 31 | 2,499
group 3 medulloblastoma 31 | 4,104
interstitial cystitis 31 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 31 | 2,989
Breast cancer 30 | 3,578
non-small cell lung cancer 30 | 2,890
pancreatic cancer 29 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
lung adenocarcinoma 27 | 2,716
tuberculosis 27 | 2,010
ulcerative colitis 27 | 1,819
Multiple myeloma 22 | 1,332
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
colon cancer 21 | 1,478
juvenile dermatomyositis 21 | 1,187
cystic fibrosis 20 | 1,696
oligodendroglioma 20 | 2,850
subependymal giant cell astrocytoma 20 | 2,287
Rheumatoid arthritis 19 | 1,191
acute quadriplegic myopathy 19 | 1,158
cutaneous lupus erythematosus 19 | 1,057
pituitary cancer 19 | 1,972
Autosomal recessive predisposition 18 | 1,442
breast carcinoma 18 | 1,638
ductal carcinoma in situ 18 | 1,745
primary pancreatic ductal adenocarcinoma 18 | 1,109
group 4 medulloblastoma 17 | 1,855
primitive neuroectodermal tumor 17 | 3,035
primary Sjogren syndrome 16 | 735
Kidney cancer 15 | 2,613
Waldenstrons macroglobulinemia 15 | 765
adrenocortical carcinoma 15 | 1,428
astrocytic glioma 15 | 2,597
Liver Cirrhosis, Experimental 14 | 769
active Crohn's disease 14 | 922
dermatomyositis 14 | 966
diabetes mellitus 14 | 1,728
pediatric high grade glioma 14 | 1,064
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
Duchenne muscular dystrophy 11 | 601
active ulcerative colitis 11 | 764
astrocytoma 11 | 1,146
fibroadenoma 11 | 559
non primary Sjogren syndrome sicca 11 | 891
Schizophrenia 10 | 1,160
acute myeloid leukemia 10 | 783
nasopharyngeal carcinoma 10 | 1,058
Intellectual disability 9 | 1,016
Pick disease 9 | 1,894
gastric carcinoma 9 | 807
mucosa-associated lymphoid tissue lymphoma 9 | 484
periodontitis 9 | 293
Kidney disease 8 | 430
esophageal adenocarcinoma 8 | 737
Alzheimer's disease 7 | 658
Amyotrophic lateral sclerosis 7 | 451
Arthritis 7 | 290
Atherosclerosis 7 | 291
Atopic dermatitis 7 | 952
Bipolar Disorder 7 | 666
Cognitive delay 7 | 608
Dull intelligence 7 | 645
Global developmental delay 7 | 608
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental and motor retardation 7 | 608
Mental deficiency 7 | 645
Neurodegenerative disease 7 | 414
Optic Atrophy 7 | 242
Poor school performance 7 | 645
Prostatic Neoplasms 7 | 495
hereditary spastic paraplegia 7 | 318
medulloblastoma 7 | 720
posterior fossa group A ependymoma 7 | 468
Asthma 6 | 385
Cataract 6 | 297
Endometriosis 6 | 540
Hepatomegaly 6 | 285
Melanoma 6 | 711
Short stature 6 | 531
aldosterone-producing adenoma 6 | 665
limb girdle muscular dystrophy 2A 6 | 213
nephrosclerosis 6 | 333
progressive supranuclear palsy 6 | 676
spina bifida 6 | 1,074

Tissue

Blood and immune system 144 | 16,909
Digestive Tract 144 | 17,369
Endocrine System 144 | 18,159
Female tissues 144 | 17,400
Male tissues 144 | 17,142
Urinary Tract 144 | 16,678
Respiratory system 143 | 16,393
Skin and soft tissues 143 | 17,230
Liver and Pancreas 142 | 16,750
Cardiovascular System 139 | 15,192
Nervous System 139 | 16,725

Target Family

Non-IDG 88 | 12,091
Enzyme 39 | 4,145
Kinase 6 | 634
Transcription Factor 6 | 1,400
GPCR 3 | 408
Ion Channel 2 | 344
TF/Epigenetic 2 | 38
Epigenetic 1 | 242
Transporter 1 | 473

Jensen-KB Tissue

Synovium 148 | 148
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nascent polypeptide-associated complex subunit alpha NACA Tbio Non-IDG -1.15827 23.3 50
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243
Nuclear receptor 2C2-associated protein NR2C2AP Tbio Non-IDG -0.49369 3.49 124
Nascent polypeptide-associated complex subunit alpha, muscle-specific form NACA Tbio Non-IDG -1.15827 23.3 50
MBT domain-containing protein 1 MBTD1 Tdark Epigenetic -0.59314 4.06 83
Protein unc-13 homolog D UNC13D Tbio Non-IDG -1.93790 85.1 158
Eukaryotic translation initiation factor 3 subunit C EIF3C Tbio Non-IDG -1.20680 14.1 159
DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G Tbio Non-IDG -2.78510 662.2 477
Neuroblastoma suppressor of tumorigenicity 1 NBL1 Tbio Non-IDG -2.58132 362.9 217
Protein AF-9 MLLT3 Tbio Non-IDG -1.99555 93.8 210