Development Level

Tbio 42 | 10,625
Tdark 16 | 7,003
Tchem 9 | 1,890
Tclin 5 | 602

IMPC Term

preweaning lethality, complete... 6 | 633
abnormal lens morphology 3 | 73
embryonic lethality prior to o... 3 | 148
embryonic lethality prior to t... 3 | 187
preweaning lethality, incomple... 3 | 260
abnormal behavior 2 | 226
abnormal embryo size 2 | 112
decreased body weight 2 | 174
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 68
abnormal behavioral response t... 1 | 52
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal head shape 1 | 4
abnormal limb morphology 1 | 7
abnormal maxilla morphology 1 | 16
abnormal outer ear morphology 1 | 1
abnormal retinal vasculature m... 1 | 15
absent startle reflex 1 | 15
aorta dilation 1 | 3
cataract 1 | 26
cyanosis 1 | 6
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating glucose ... 1 | 121
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
hemorrhage 1 | 12
hyperactivity 1 | 108
hypoactivity 1 | 89
immune system phenotype 1 | 17
increased cardiac stroke volum... 1 | 1
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating creatine... 1 | 2
increased circulating free fat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased exploration in new e... 1 | 56
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 25
increased or absent threshold ... 1 | 128
male infertility 1 | 62
prenatal lethality prior to he... 1 | 64
small testis 1 | 37

Disease

osteosarcoma 37 | 7,933
ovarian cancer 35 | 8,484
medulloblastoma, large-cell 27 | 6,234
psoriasis 26 | 6,685
glioblastoma 25 | 5,572
atypical teratoid / rhabdoid tumor 20 | 4,369
lung cancer 20 | 4,466
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
invasive ductal carcinoma 15 | 2,950
pilocytic astrocytoma 15 | 3,086
adult high grade glioma 13 | 2,148
interstitial cystitis 13 | 2,299
oligodendroglioma 13 | 2,849
malignant mesothelioma 12 | 3,162
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Breast cancer 11 | 3,094
primitive neuroectodermal tumor 11 | 3,031
subependymal giant cell astrocytoma 11 | 2,287
Cancer 10 | 2,346
astrocytic glioma 10 | 2,241
ependymoma 10 | 2,514
lung carcinoma 10 | 2,844
non-small cell lung cancer 10 | 2,798
astrocytoma 9 | 1,493
cutaneous lupus erythematosus 9 | 1,056
lung adenocarcinoma 9 | 2,713
pediatric high grade glioma 9 | 2,712
pituitary cancer 9 | 1,972
tuberculosis 9 | 1,557
ulcerative colitis 9 | 2,087
Carcinoma 8 | 2,147
cystic fibrosis 8 | 1,665
ductal carcinoma in situ 8 | 1,745
group 4 medulloblastoma 8 | 1,875
medulloblastoma 8 | 1,524
Atopic dermatitis 7 | 944
Obesity 7 | 616
Pick disease 7 | 1,893
Rheumatoid Arthritis 7 | 1,160
adrenocortical carcinoma 7 | 1,427
breast carcinoma 7 | 1,614
group 3 medulloblastoma 7 | 2,254
pancreatic cancer 7 | 2,300
Multiple myeloma 6 | 1,327
colon cancer 6 | 1,475
posterior fossa group B ependymoma 6 | 1,530
Parkinson's disease 5 | 364
aldosterone-producing adenoma 5 | 664
diabetes mellitus 5 | 1,663
juvenile dermatomyositis 5 | 1,189
primary pancreatic ductal adenocarcinoma 5 | 1,271
sonic hedgehog group medulloblastoma 5 | 1,482
Multiple Sclerosis 4 | 498
Neurodegenerative disease 4 | 383
Toxic encephalopathy 4 | 131
Vascular disease 4 | 281
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 430
gastric carcinoma 4 | 832
nasopharyngeal carcinoma 4 | 1,056
posterior fossa group A ependymoma 4 | 1,511
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064
Cocaine dependence 3 | 24
Epilepsy 3 | 346
Leigh disease 3 | 81
Schizophrenia 3 | 501
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 918
acute quadriplegic myopathy 3 | 1,157
non-small cell lung carcinoma 3 | 413
primary Sjogren syndrome 3 | 789
urothelial carcinoma 3 | 318
Acquired metabolic disease 2 | 267
Adenoma 2 | 165
Alzheimer's disease 2 | 644
Amyotrophic Lateral Sclerosis 2 | 431
Animal Mammary Neoplasms 2 | 136
Attention deficit hyperactivity disorder 2 | 156
Colorectal Neoplasms 2 | 217
Coronary artery disease 2 | 240
Gout 2 | 93
Hirschsprung's disease 2 | 42
Malaria 2 | 140
Mammary Neoplasms 2 | 410
Mammary Neoplasms, Experimental 2 | 150
Neoplastic Syndromes, Hereditary 2 | 48
Nicotine dependence 2 | 53
Osteoporosis 2 | 257
Paraganglioma 2 | 12
Pellagra 2 | 25
Prostatic Neoplasms 2 | 471
acute myeloid leukemia 2 | 780
chronic lymphosyte leukemia 2 | 232
dermatomyositis 2 | 933
fibroadenoma 2 | 557
inflammatory breast cancer 2 | 404
mucosa-associated lymphoid tissue lymphoma 2 | 480

Tissue

Digestive Tract 72 | 18,473
Endocrine System 72 | 18,512
Nervous System 72 | 18,561
Urinary Tract 72 | 18,444
Female tissues 71 | 18,647
Liver and Pancreas 71 | 18,136
Skin and soft tissues 71 | 18,115
Blood and immune system 70 | 17,995
Cardiovascular System 70 | 17,958
Male tissues 70 | 17,969
Respiratory system 70 | 17,484

Target Family

Non-IDG 38 | 11,971
Enzyme 17 | 4,146
Transcription Factor 9 | 1,400
Ion Channel 3 | 341
Transporter 2 | 473
Epigenetic 1 | 242
GPCR 1 | 406
Kinase 1 | 634

Jensen-KB Tissue

Substantia nigra 72 | 72
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Malate dehydrogenase, cytoplasmic MDH1 Tbio Enzyme -2.61325 409.6 244
Zinc finger and SCAN domain-containing protein 1 ZSCAN1 Tbio Transcription Factor -1.37888 19.7 80
Zinc finger protein 439 ZNF439 Tdark Transcription Factor 0.00000 14
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.59340 415.3 337
Glutathione synthetase GSS Tbio Enzyme -2.75264 568.9 200
Zinc finger protein 34 ZNF34 Tdark Transcription Factor -0.42943 2.59 44
Ribosomal L1 domain-containing protein 1 RSL1D1 Tbio Non-IDG -1.24451 20.3 112
Zinc finger protein 584 ZNF584 Tdark Transcription Factor 0.17 31
Vasodilator-stimulated phosphoprotein VASP Tbio Non-IDG -2.92544 883.0 726
SUN domain-containing protein 1 SUN1 Tbio Non-IDG -1.65634 48.2 53