Development Level

Tbio 46 | 11,651
Tdark 17 | 6,593
Tchem 5 | 1,388
Tclin 5 | 612

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased body weight 2 | 161
decreased grip strength 2 | 116
hyperactivity 2 | 148
increased circulating sodium l... 2 | 71
male infertility 2 | 123
small testis 2 | 58
abnormal behavioral response t... 1 | 66
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal limb morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal outer ear morphology 1 | 3
abnormal retinal vasculature m... 1 | 27
abnormal sleep behavior 1 | 70
absent startle reflex 1 | 24
anophthalmia 1 | 33
aorta dilation 1 | 3
cyanosis 1 | 7
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
dilated heart left ventricle 1 | 11
enlarged heart 1 | 210
female infertility 1 | 60
hemorrhage 1 | 23
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased cardiac stroke volum... 1 | 1
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating creatine... 1 | 5
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 48 | 11,493
osteosarcoma 37 | 7,950
ovarian cancer 35 | 8,520
glioblastoma 28 | 5,792
medulloblastoma, large-cell 27 | 6,241
psoriasis 26 | 6,694
atypical teratoid / rhabdoid tumor 22 | 5,112
lung cancer 20 | 4,740
adult high grade glioma 19 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
ependymoma 17 | 4,679
Astrocytoma, Pilocytic 16 | 3,081
group 3 medulloblastoma 16 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
invasive ductal carcinoma 15 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
interstitial cystitis 13 | 2,312
oligodendroglioma 13 | 2,850
malignant mesothelioma 12 | 3,232
non-small cell lung cancer 12 | 2,890
Breast cancer 11 | 3,578
Kidney cancer 11 | 2,613
Schizophrenia 11 | 1,160
primitive neuroectodermal tumor 11 | 3,035
subependymal giant cell astrocytoma 11 | 2,287
Autosomal recessive predisposition 10 | 1,442
Cancer 10 | 2,499
astrocytic glioma 10 | 2,597
group 4 medulloblastoma 10 | 1,855
lung carcinoma 10 | 2,843
tuberculosis 10 | 2,010
Epilepsy 9 | 792
astrocytoma 9 | 1,146
cutaneous lupus erythematosus 9 | 1,057
lung adenocarcinoma 9 | 2,716
pituitary cancer 9 | 1,972
ulcerative colitis 9 | 1,819
breast carcinoma 8 | 1,638
cystic fibrosis 8 | 1,696
ductal carcinoma in situ 8 | 1,745
Atopic dermatitis 7 | 952
Bipolar Disorder 7 | 666
Dysarthria 7 | 192
Muscle hypotonia 7 | 571
Obesity 7 | 678
Pick disease 7 | 1,894
Rheumatoid arthritis 7 | 1,191
Seizures 7 | 596
Vascular disease 7 | 319
adrenocortical carcinoma 7 | 1,428
pancreatic cancer 7 | 2,398
Cerebellar Ataxia 6 | 304
Depressive disorder 6 | 409
Intellectual disability 6 | 1,016
Multiple myeloma 6 | 1,332
Nystagmus 6 | 317
colon cancer 6 | 1,478
Cognitive delay 5 | 608
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Liver Cirrhosis, Experimental 5 | 769
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Neurodegenerative disease 5 | 414
Optic Atrophy 5 | 242
Parkinson's disease 5 | 392
Poor school performance 5 | 645
Respiratory Failure 5 | 104
Sensorineural Hearing Loss (disorder) 5 | 284
aldosterone-producing adenoma 5 | 665
diabetes mellitus 5 | 1,728
juvenile dermatomyositis 5 | 1,187
Blepharoptosis 4 | 231
Fatigue 4 | 182
Hyperreflexia 4 | 209
Mental Depression 4 | 333
Multiple Sclerosis 4 | 540
Muscle Spasticity 4 | 195
Retinitis Pigmentosa 4 | 226
Strabismus 4 | 270
Toxic encephalopathy 4 | 141
esophageal adenocarcinoma 4 | 737
gastric cancer 4 | 459
gastric carcinoma 4 | 807
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
posterior fossa group A ependymoma 4 | 468
progressive supranuclear palsy 4 | 676
spina bifida 4 | 1,074
Attention deficit hyperactivity disorder 3 | 278
Failure to gain weight 3 | 365
Pediatric failure to thrive 3 | 365
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
urothelial carcinoma 3 | 318

Tissue

Male tissues 73 | 17,142
Blood and immune system 72 | 16,909
Endocrine System 72 | 18,159
Female tissues 72 | 17,400
Digestive Tract 71 | 17,369
Liver and Pancreas 71 | 16,750
Nervous System 71 | 16,725
Respiratory system 71 | 16,393
Skin and soft tissues 70 | 17,230
Urinary Tract 69 | 16,678
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 39 | 12,091
Enzyme 17 | 4,145
Transcription Factor 9 | 1,400
Ion Channel 3 | 344
Transporter 2 | 473
Epigenetic 1 | 242
GPCR 1 | 408
Kinase 1 | 634

Jensen-KB Tissue

Substantia nigra 73 | 73
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ganglioside GM2 activator GM2A Tbio Non-IDG -2.03952 111.9 325
Soluble calcium-activated nucleotidase 1 CANT1 Tbio Enzyme -1.42839 27.2 210
Protein sprouty homolog 2 SPRY2 Tbio Non-IDG -1.90829 87.6 217
Complement C1q tumor necrosis factor-related protein 3 C1QTNF3 Tbio Non-IDG -2.37205 248.3 107
SUN domain-containing protein 1 SUN1 Tbio Non-IDG -1.74780 53.6 58
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 ABHD5 Tbio Enzyme -1.95524 94.8 243
Ena/VASP-like protein EVL Tbio Non-IDG -2.21334 170.1 137
Probable lysosomal cobalamin transporter LMBRD1 Tbio Non-IDG -2.10518 126.1 54
DNA mismatch repair protein Mlh1 MLH1 Tbio Non-IDG -3.34283 2352.6 495
COBW domain-containing protein 2 CBWD2 Tdark Non-IDG 0.00000 27