Development Level

Tbio 435 | 11,445
Tdark 98 | 6,588
Tchem 69 | 1,598
Tclin 18 | 613

Collection

Kinase: IDG Consortium (Target... 3 | 125
GPCR: IDG Consortium (Complete... 2 | 25
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 21 | 979
preweaning lethality, incomple... 17 | 499
enlarged heart 9 | 210
decreased body weight 7 | 161
decreased circulating glucose ... 7 | 126
decreased circulating serum al... 7 | 82
decreased total body fat amoun... 7 | 207
decreased vertical activity 7 | 208
embryonic lethality prior to t... 7 | 278
hyperactivity 7 | 148
abnormal heart morphology 6 | 162
decreased lean body mass 6 | 135
decreased leukocyte cell numbe... 6 | 73
increased circulating alkaline... 6 | 122
short tibia 6 | 97
abnormal behavior 5 | 298
abnormal gait 5 | 69
decreased bone mineral content 5 | 151
decreased circulating choleste... 5 | 93
decreased circulating triglyce... 5 | 79
decreased grip strength 5 | 116
decreased lymphocyte cell numb... 5 | 83
embryonic lethality prior to o... 5 | 239
increased bone mineral density 5 | 72
increased lean body mass 5 | 172
abnormal embryo size 4 | 220
decreased bone mineral density 4 | 126
decreased circulating total pr... 4 | 49
impaired glucose tolerance 4 | 75
increased hematocrit 4 | 46
increased neutrophil cell numb... 4 | 46
increased startle reflex 4 | 112
increased total body fat amoun... 4 | 134
small superior vagus ganglion 4 | 74
decreased blood urea nitrogen ... 3 | 51
decreased caudal vertebrae num... 3 | 53
decreased circulating HDL chol... 3 | 68
decreased circulating chloride... 3 | 30
decreased circulating insulin ... 3 | 76
decreased erythrocyte cell num... 3 | 62
decreased hematocrit 3 | 46
decreased hemoglobin content 3 | 68
embryonic growth retardation 3 | 106
improved glucose tolerance 3 | 79
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased fasted circulating g... 3 | 76
increased leukocyte cell numbe... 3 | 47
thrombocytopenia 3 | 56
abnormal behavioral response t... 2 | 66
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
abnormal coat appearance 2 | 31
abnormal coat- hair morphology 2 | 19
abnormal coat-hair pigmentatio... 2 | 64
abnormal eye morphology 2 | 68
abnormal kidney morphology 2 | 65
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased circulating alkaline... 2 | 46
decreased circulating free fat... 2 | 31
decreased circulating sodium l... 2 | 22
decreased fasted circulating g... 2 | 65
decreased heart weight 2 | 27
decreased lactate dehydrogenas... 2 | 16
decreased mature B cell number 2 | 7
decreased prepulse inhibition 2 | 82
hydrometra 2 | 53
hypoactivity 2 | 132
increased B cell number 2 | 9
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased circulating chloride... 2 | 41
increased circulating creatini... 2 | 38
increased circulating glucose ... 2 | 24
increased circulating insulin ... 2 | 3
increased circulating iron lev... 2 | 30
increased erythrocyte cell num... 2 | 39
increased grip strength 2 | 41
increased heart weight 2 | 62
increased mean corpuscular hem... 2 | 36
increased monocyte cell number 2 | 63
increased prepulse inhibition 2 | 32
polycystic kidney 2 | 15
prenatal lethality 2 | 28
prenatal lethality prior to he... 2 | 87
vertebral transformation 2 | 12
abnormal ear morphology 1 | 9
abnormal optic disc morphology 1 | 10
abnormal vertebrae morphology 1 | 18
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating potassiu... 1 | 20
decreased neutrophil cell numb... 1 | 42
impaired pupillary reflex 1 | 26
increased cardiac muscle contr... 1 | 8
increased circulating triglyce... 1 | 42
increased mean corpuscular vol... 1 | 92

Disease

Carcinoma 389 | 11,493
osteosarcoma 326 | 7,950
ovarian cancer 282 | 8,520
psoriasis 222 | 6,694
glioblastoma 204 | 5,792
medulloblastoma, large-cell 191 | 6,241
lung cancer 167 | 4,740
atypical teratoid / rhabdoid tumor 150 | 5,112
interstitial cystitis 150 | 2,312
invasive ductal carcinoma 143 | 2,951
lung carcinoma 140 | 2,843
Breast cancer 131 | 3,578
non-small cell lung cancer 130 | 2,890
ependymoma 125 | 4,679
Cancer 123 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 123 | 3,291
adult high grade glioma 121 | 3,801
lung adenocarcinoma 118 | 2,716
group 3 medulloblastoma 116 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 116 | 2,989
malignant mesothelioma 114 | 3,232
Astrocytoma, Pilocytic 113 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 112 | 2,955
ulcerative colitis 109 | 1,819
pancreatic cancer 108 | 2,398
tuberculosis 105 | 2,010
subependymal giant cell astrocytoma 99 | 2,287
Kidney cancer 89 | 2,613
primitive neuroectodermal tumor 83 | 3,035
breast carcinoma 82 | 1,638
diabetes mellitus 80 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 77 | 1,962
cutaneous lupus erythematosus 73 | 1,057
group 4 medulloblastoma 70 | 1,855
cystic fibrosis 69 | 1,696
oligodendroglioma 69 | 2,850
ductal carcinoma in situ 67 | 1,745
primary Sjogren syndrome 67 | 735
astrocytic glioma 62 | 2,597
adrenocortical carcinoma 61 | 1,428
pituitary cancer 61 | 1,972
Rheumatoid arthritis 60 | 1,191
Pick disease 59 | 1,894
juvenile dermatomyositis 59 | 1,187
Liver Cirrhosis, Experimental 57 | 769
primary pancreatic ductal adenocarcinoma 55 | 1,109
Autosomal recessive predisposition 53 | 1,442
astrocytoma 51 | 1,146
colon cancer 48 | 1,478
acute quadriplegic myopathy 43 | 1,158
pediatric high grade glioma 42 | 1,064
Multiple myeloma 41 | 1,332
dermatomyositis 41 | 966
gastric carcinoma 41 | 807
Atopic dermatitis 39 | 952
nasopharyngeal carcinoma 39 | 1,058
Duchenne muscular dystrophy 36 | 601
spina bifida 35 | 1,074
Schizophrenia 33 | 1,160
active Crohn's disease 33 | 922
acute myeloid leukemia 33 | 783
esophageal adenocarcinoma 33 | 737
Melanoma 32 | 711
pancreatic carcinoma 32 | 562
Intellectual disability 30 | 1,016
non primary Sjogren syndrome sicca 30 | 891
Obesity 29 | 678
Waldenstrons macroglobulinemia 29 | 765
hepatocellular carcinoma 29 | 547
mucosa-associated lymphoid tissue lymphoma 29 | 484
gastric cancer 28 | 459
Chronic Lymphocytic Leukemia 26 | 262
fibroadenoma 26 | 559
Liver cancer 25 | 604
active ulcerative colitis 24 | 764
sonic hedgehog group medulloblastoma 24 | 467
Multiple Sclerosis 23 | 540
head and neck cancer and chronic obstructive pulmonary disease 23 | 239
periodontitis 23 | 293
Atherosclerosis 22 | 291
aldosterone-producing adenoma 22 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 22 | 510
progressive supranuclear palsy 22 | 676
Arthritis, Rheumatoid 21 | 174
posterior fossa group A ependymoma 21 | 468
Epilepsy 20 | 792
head and neck cancer 20 | 271
Short stature 19 | 531
Kidney disease 18 | 430
Muscle hypotonia 18 | 571
Polycystic ovary syndrome 18 | 360
chronic lymphosyte leukemia 18 | 204
medulloblastoma 18 | 720
sarcoidosis 18 | 370
Alzheimer's disease 17 | 658
Cognitive delay 17 | 608
Endometriosis 17 | 540
Global developmental delay 17 | 608
Mental and motor retardation 17 | 608
Prostatic Neoplasms 17 | 495

Tissue

Digestive Tract 611 | 17,369
Blood and immune system 609 | 16,909
Female tissues 606 | 17,400
Skin and soft tissues 606 | 17,230
Endocrine System 605 | 18,159
Liver and Pancreas 604 | 16,750
Urinary Tract 604 | 16,678
Male tissues 601 | 17,142
Respiratory system 597 | 16,393
Nervous System 585 | 16,725
Cardiovascular System 574 | 15,192

Target Family

Non-IDG 373 | 12,091
Enzyme 135 | 4,145
Transcription Factor 40 | 1,400
Kinase 18 | 634
Transporter 14 | 473
Epigenetic 13 | 242
GPCR 13 | 408
Ion Channel 8 | 344
Nuclear Receptor 4 | 48
TF/Epigenetic 2 | 38

Jensen-KB Tissue

Spleen 620 | 620
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinoic acid receptor responder protein 3 RARRES3 Tbio Non-IDG -1.84020 71.0 164
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Uridine-cytidine kinase-like 1 UCKL1 Tdark Kinase -0.15970 2.21 110
Krueppel-like factor 2 KLF2 Tbio Transcription Factor -2.30630 216.2 308
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
L-amino-acid oxidase IL4I1 Tbio Enzyme -2.79074 622.3 53
Solute carrier family 12 member 7 SLC12A7 Tbio Transporter -1.46102 28.2 156
Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 Tbio Enzyme -0.79764 6.35 32
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Mediator of RNA polymerase II transcription subunit 15 MED15 Tbio Enzyme -1.60315 40.6 144