Development Level

Tbio 53 | 11,445
Tdark 13 | 6,588
Tchem 7 | 1,598
Tclin 1 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic growth retardation 4 | 106
abnormal embryo size 3 | 220
decreased circulating glucose ... 2 | 126
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hair growth 1 | 10
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal maxilla morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal tail morphology 1 | 25
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased grip strength 1 | 41
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 54 | 11,493
ovarian cancer 44 | 8,520
osteosarcoma 36 | 7,950
psoriasis 34 | 6,694
medulloblastoma, large-cell 32 | 6,241
atypical teratoid / rhabdoid tumor 31 | 5,112
glioblastoma 30 | 5,792
ependymoma 29 | 4,679
Astrocytoma, Pilocytic 22 | 3,081
lung cancer 21 | 4,740
group 3 medulloblastoma 20 | 4,104
adult high grade glioma 19 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
invasive ductal carcinoma 18 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
astrocytic glioma 16 | 2,597
oligodendroglioma 16 | 2,850
primitive neuroectodermal tumor 16 | 3,035
subependymal giant cell astrocytoma 16 | 2,287
Breast cancer 15 | 3,578
malignant mesothelioma 15 | 3,232
non-small cell lung cancer 14 | 2,890
Pick disease 13 | 1,894
adrenocortical carcinoma 13 | 1,428
Kidney cancer 12 | 2,613
breast carcinoma 12 | 1,638
lung carcinoma 12 | 2,843
pituitary cancer 12 | 1,972
tuberculosis 12 | 2,010
acute quadriplegic myopathy 11 | 1,158
cystic fibrosis 11 | 1,696
ductal carcinoma in situ 11 | 1,745
colon cancer 10 | 1,478
group 4 medulloblastoma 10 | 1,855
juvenile dermatomyositis 10 | 1,187
lung adenocarcinoma 10 | 2,716
pancreatic cancer 10 | 2,398
Atopic dermatitis 9 | 952
Schizophrenia 9 | 1,160
diabetes mellitus 9 | 1,728
pediatric high grade glioma 9 | 1,064
Neurodegenerative disease 8 | 414
active Crohn's disease 8 | 922
active ulcerative colitis 8 | 764
astrocytoma 8 | 1,146
dermatomyositis 8 | 966
interstitial cystitis 8 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Down syndrome 7 | 499
Cancer 6 | 2,499
Liver Cirrhosis, Experimental 6 | 769
Neuropathy 6 | 261
aldosterone-producing adenoma 6 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
non primary Sjogren syndrome sicca 6 | 891
progressive supranuclear palsy 6 | 676
Alzheimer's disease 5 | 658
Autosomal recessive predisposition 5 | 1,442
Rheumatoid arthritis 5 | 1,191
acute myeloid leukemia 5 | 783
hereditary spastic paraplegia 5 | 318
primary pancreatic ductal adenocarcinoma 5 | 1,109
Amyotrophic lateral sclerosis 4 | 451
Cerebellar Ataxia 4 | 304
Charcot-Marie-Tooth disease 4 | 62
Duchenne muscular dystrophy 4 | 601
Infantile onset 4 | 238
Intellectual disability 4 | 1,016
Melanoma 4 | 711
Parkinson's disease 4 | 392
Waldenstrons macroglobulinemia 4 | 765
fibroadenoma 4 | 559
medulloblastoma 4 | 720
sarcoidosis 4 | 370
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Abnormality of the immune system 3 | 18
Alcoholic Intoxication, Chronic 3 | 289
Attention deficit hyperactivity disorder 3 | 278
Chronic Lymphocytic Leukemia 3 | 262
Congenital pes cavus 3 | 88
Congestive heart failure 3 | 113
Coronary artery disease 3 | 268
Deglutition Disorders 3 | 132
Kidney disease 3 | 430
Large intestine cancer 3 | 126
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Paraplegia 3 | 74
Skin cancer 3 | 469
Slow progression 3 | 89
cutaneous lupus erythematosus 3 | 1,057
gastric carcinoma 3 | 807
inflammatory breast cancer 3 | 286
nasopharyngeal carcinoma 3 | 1,058
primary Sjogren syndrome 3 | 735
urothelial carcinoma 3 | 318
head and neck cancer 2 | 271

Tissue

Endocrine System 74 | 18,159
Digestive Tract 72 | 17,369
Female tissues 72 | 17,400
Nervous System 72 | 16,725
Skin and soft tissues 72 | 17,230
Male tissues 71 | 17,142
Liver and Pancreas 69 | 16,750
Urinary Tract 69 | 16,678
Respiratory system 68 | 16,393
Blood and immune system 67 | 16,909
Cardiovascular System 61 | 15,192

Target Family

Non-IDG 47 | 12,091
Enzyme 15 | 4,145
Transcription Factor 5 | 1,400
Transporter 3 | 473
GPCR 2 | 408
Ion Channel 2 | 344

Jensen-KB Tissue

Spinal cord 74 | 74
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
Homeobox protein Hox-D9 HOXD9 Tbio Transcription Factor -1.52954 36.2 137
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tbio Enzyme -1.93041 83.4 177
Transcription factor SOX-21 SOX21 Tbio Transcription Factor -1.47198 29.1 106
Proton-coupled folate transporter SLC46A1 Tchem Transporter -2.23182 177.1 76
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase METTL16 Tbio Enzyme -0.54935 4.80 160
E3 ubiquitin-protein ligase RNF19A RNF19A Tbio Enzyme -1.12489 15.5 142
Guanylate-binding protein 4 GBP4 Tbio Non-IDG -1.68193 45.8 122
Peripheral myelin protein 22 PMP22 Tbio Non-IDG -2.50612 344.4 262
Myelin protein P0 MPZ Tbio Non-IDG -2.55919 360.1 301