Development Level

Tbio 195 | 11,445
Tdark 92 | 6,588
Tchem 30 | 1,598
Tclin 13 | 613

Collection

RFA-RM-18-021 6 | 328
Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 10 | 499
abnormal behavior 6 | 298
decreased vertical activity 5 | 208
decreased total body fat amoun... 4 | 207
increased circulating sodium l... 4 | 71
increased mean corpuscular hem... 4 | 96
abnormal bone structure 3 | 187
abnormal embryo size 3 | 220
embryonic lethality prior to o... 3 | 239
enlarged heart 3 | 210
hyperactivity 3 | 148
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased mean platelet volume 3 | 45
abnormal seminal vesicle morph... 2 | 114
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased circulating glucose ... 2 | 126
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 31
decreased mean corpuscular vol... 2 | 79
edema 2 | 59
embryonic lethality prior to t... 2 | 278
hydrometra 2 | 53
impaired righting response 2 | 26
increased blood urea nitrogen ... 2 | 48
increased bone mineral content 2 | 108
increased circulating creatini... 2 | 38
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
prenatal lethality prior to he... 2 | 87
prolonged ST segment 2 | 36
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal nail morphology 1 | 8
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased basophil cell number 1 | 16
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased startle reflex 1 | 75
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
enlarged spleen 1 | 41
female infertility 1 | 60
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased aggression 1 | 4
increased bone mineral density 1 | 72
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
male infertility 1 | 123
prolonged QT interval 1 | 38
short tibia 1 | 97
small testis 1 | 58
vertebral transformation 1 | 12

Disease

Carcinoma 179 | 11,493
osteosarcoma 156 | 7,950
ovarian cancer 151 | 8,520
psoriasis 122 | 6,694
medulloblastoma, large-cell 94 | 6,241
glioblastoma 89 | 5,792
lung cancer 85 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 83 | 3,291
atypical teratoid / rhabdoid tumor 80 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 75 | 2,989
ependymoma 74 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 73 | 2,955
Breast cancer 72 | 3,578
lung adenocarcinoma 69 | 2,716
adult high grade glioma 64 | 3,801
non-small cell lung cancer 64 | 2,890
invasive ductal carcinoma 58 | 2,951
pancreatic cancer 58 | 2,398
colon cancer 56 | 1,478
group 3 medulloblastoma 56 | 4,104
lung carcinoma 53 | 2,843
interstitial cystitis 51 | 2,312
Astrocytoma, Pilocytic 50 | 3,081
malignant mesothelioma 49 | 3,232
subependymal giant cell astrocytoma 49 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 48 | 1,962
ulcerative colitis 45 | 1,819
Cancer 44 | 2,499
oligodendroglioma 42 | 2,850
tuberculosis 41 | 2,010
ductal carcinoma in situ 38 | 1,745
primitive neuroectodermal tumor 38 | 3,035
astrocytic glioma 37 | 2,597
Kidney cancer 36 | 2,613
Pick disease 35 | 1,894
cystic fibrosis 35 | 1,696
active ulcerative colitis 33 | 764
nasopharyngeal carcinoma 33 | 1,058
diabetes mellitus 32 | 1,728
pituitary cancer 32 | 1,972
breast carcinoma 31 | 1,638
active Crohn's disease 30 | 922
cutaneous lupus erythematosus 30 | 1,057
Multiple myeloma 29 | 1,332
Autosomal recessive predisposition 28 | 1,442
primary pancreatic ductal adenocarcinoma 26 | 1,109
non primary Sjogren syndrome sicca 24 | 891
adrenocortical carcinoma 23 | 1,428
spina bifida 23 | 1,074
juvenile dermatomyositis 20 | 1,187
Atopic dermatitis 19 | 952
Melanoma 19 | 711
Rheumatoid arthritis 18 | 1,191
acute quadriplegic myopathy 18 | 1,158
group 4 medulloblastoma 18 | 1,855
Schizophrenia 17 | 1,160
dermatomyositis 17 | 966
esophageal adenocarcinoma 17 | 737
Multiple Sclerosis 16 | 540
Waldenstrons macroglobulinemia 16 | 765
fibroadenoma 16 | 559
primary Sjogren syndrome 16 | 735
Crohn's disease 15 | 321
Epilepsy 15 | 792
hepatocellular carcinoma 15 | 547
pediatric high grade glioma 15 | 1,064
progressive supranuclear palsy 15 | 676
gastric carcinoma 14 | 807
Alcoholic Intoxication, Chronic 13 | 289
Cognitive delay 13 | 608
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
Muscle hypotonia 13 | 571
Obesity 13 | 678
astrocytoma 13 | 1,146
chronic rhinosinusitis 13 | 512
Intellectual disability 12 | 1,016
Liver Cirrhosis, Experimental 12 | 769
Liver cancer 12 | 604
Seizures 12 | 596
pancreatic carcinoma 12 | 562
sarcoidosis 12 | 370
Alzheimer's disease 11 | 658
acute myeloid leukemia 11 | 783
gastric cancer 11 | 459
nephrosclerosis 11 | 333
Atherosclerosis 10 | 291
Down syndrome 10 | 499
Duchenne muscular dystrophy 10 | 601
Dull intelligence 10 | 645
Endometriosis 10 | 540
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Poor school performance 10 | 645
cystic fibrosis and chronic rhinosinusitis 10 | 214
medulloblastoma 10 | 720
non-small cell lung carcinoma 10 | 317
urothelial carcinoma 10 | 318
Prostatic Neoplasms 9 | 495

Tissue

Digestive Tract 322 | 17,369
Endocrine System 319 | 18,159
Skin and soft tissues 319 | 17,230
Female tissues 317 | 17,400
Urinary Tract 317 | 16,678
Liver and Pancreas 315 | 16,750
Male tissues 314 | 17,142
Blood and immune system 309 | 16,909
Nervous System 306 | 16,725
Respiratory system 303 | 16,393
Cardiovascular System 290 | 15,192

Target Family

Non-IDG 180 | 12,091
Enzyme 85 | 4,145
Transcription Factor 22 | 1,400
Transporter 16 | 473
Ion Channel 8 | 344
Kinase 8 | 634
GPCR 7 | 408
Epigenetic 3 | 242
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Small intestine 330 | 330
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alcohol dehydrogenase 6 ADH6 Tbio Enzyme -1.84121 71.7 117
Serine/threonine-protein kinase pim-3 PIM3 Tchem Kinase -1.87886 77.4 105
Rho GTPase-activating protein 9 ARHGAP9 Tbio Enzyme -1.74771 54.3 35
Magnesium-dependent phosphatase 1 MDP1 Tdark Enzyme -0.52288 4.23 35
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
Uncharacterized protein C2orf42 C2orf42 Tdark Non-IDG 0.95 0.09 69
POU domain, class 2, transcription factor 3 POU2F3 Tbio Transcription Factor -2.50813 322.4 96
THO complex subunit 7 homolog THOC7 Tbio Non-IDG -0.34772 2.04 61
Acid-sensing ion channel 5 ASIC5 Tbio Ion Channel -0.41218 3.22 86
RING finger protein 186 RNF186 Tdark Non-IDG -0.60669 4.57 78