Development Level

Tbio 177 | 10,625
Tdark 100 | 7,003
Tchem 37 | 1,890
Tclin 13 | 602

Collection

Eligible Ion Channel Proteins 5 | 117
Eligible Kinase Proteins 2 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

abnormal behavior 7 | 226
preweaning lethality, complete... 7 | 633
preweaning lethality, incomple... 6 | 260
decreased bone mineral content 5 | 157
abnormal retina morphology 4 | 100
decreased bone mineral density 4 | 126
decreased total body fat amoun... 4 | 186
hyperactivity 4 | 108
increased circulating sodium l... 4 | 71
abnormal eye morphology 3 | 38
decreased body length 3 | 108
decreased circulating glucose ... 3 | 121
increased mean corpuscular hem... 3 | 93
increased mean corpuscular vol... 3 | 91
short tibia 3 | 82
abnormal embryo size 2 | 112
abnormal lens morphology 2 | 73
decreased caudal vertebrae num... 2 | 49
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased mean corpuscular vol... 2 | 50
decreased rib number 2 | 59
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
hydrops fetalis 2 | 22
hypoactivity 2 | 89
increased bone mineral density 2 | 52
increased circulating alkaline... 2 | 119
increased mean platelet volume 2 | 19
increased startle reflex 2 | 38
prenatal lethality prior to he... 2 | 64
abnormal QRS complex 1 | 25
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal cervical vertebrae mo... 1 | 4
abnormal coat appearance 1 | 25
abnormal digit morphology 1 | 13
abnormal gait 1 | 51
abnormal locomotor activation 1 | 26
abnormal motor coordination/ b... 1 | 4
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal thoracic vertebrae mo... 1 | 16
anophthalmia 1 | 20
cardiovascular system phenotyp... 1 | 35
corneal opacity 1 | 25
decreased B cell number 1 | 30
decreased CD4-positive, CD25-p... 1 | 24
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C high monocyte n... 1 | 18
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased basophil cell number 1 | 11
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating serum al... 1 | 79
decreased effector memory CD4-... 1 | 6
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased total retina thickne... 1 | 20
enlarged spleen 1 | 26
impaired righting response 1 | 19
increased aggression 1 | 2
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased circulating serum al... 1 | 25
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart weight 1 | 37
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased red blood cell distr... 1 | 21
increased sacral vertebrae num... 1 | 62
limb grasping 1 | 35
prolonged QT interval 1 | 3
rib fusion 1 | 2
straub tail 1 | 26
vertebral fusion 1 | 23
vertebral transformation 1 | 12

Disease

osteosarcoma 156 | 7,933
ovarian cancer 149 | 8,484
psoriasis 122 | 6,685
medulloblastoma, large-cell 94 | 6,234
glioblastoma 88 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 83 | 3,289
lung cancer 81 | 4,466
intraductal papillary-mucinous carcinoma (IPMC) 75 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 72 | 2,956
atypical teratoid / rhabdoid tumor 69 | 4,369
lung adenocarcinoma 69 | 2,713
Breast cancer 66 | 3,094
non-small cell lung cancer 61 | 2,798
invasive ductal carcinoma 58 | 2,950
ulcerative colitis 58 | 2,087
pancreatic cancer 57 | 2,300
colon cancer 55 | 1,475
lung carcinoma 54 | 2,844
interstitial cystitis 51 | 2,299
pilocytic astrocytoma 51 | 3,086
subependymal giant cell astrocytoma 49 | 2,287
malignant mesothelioma 48 | 3,162
pancreatic ductal adenocarcinoma liver metastasis 45 | 1,795
pediatric high grade glioma 44 | 2,712
Cancer 42 | 2,346
oligodendroglioma 42 | 2,849
ductal carcinoma in situ 38 | 1,745
primitive neuroectodermal tumor 38 | 3,031
ependymoma 36 | 2,514
adult high grade glioma 35 | 2,148
Pick disease 34 | 1,893
cystic fibrosis 33 | 1,665
group 3 medulloblastoma 33 | 2,254
nasopharyngeal carcinoma 33 | 1,056
astrocytic glioma 32 | 2,241
pituitary cancer 32 | 1,972
breast carcinoma 31 | 1,614
active Crohn's disease 30 | 918
cutaneous lupus erythematosus 30 | 1,056
tuberculosis 30 | 1,557
Multiple myeloma 29 | 1,327
diabetes mellitus 29 | 1,663
Carcinoma 28 | 2,147
primary pancreatic ductal adenocarcinoma 28 | 1,271
posterior fossa group B ependymoma 27 | 1,530
adrenocortical carcinoma 23 | 1,427
spina bifida 23 | 1,064
medulloblastoma 21 | 1,524
posterior fossa group A ependymoma 21 | 1,511
dermatomyositis 20 | 933
juvenile dermatomyositis 20 | 1,189
non primary Sjogren syndrome sicca 20 | 840
Atopic dermatitis 19 | 944
active ulcerative colitis 19 | 477
group 4 medulloblastoma 19 | 1,875
primary Sjogren syndrome 19 | 789
sonic hedgehog group medulloblastoma 19 | 1,482
Rheumatoid Arthritis 18 | 1,160
acute quadriplegic myopathy 18 | 1,157
astrocytoma 17 | 1,493
esophageal adenocarcinoma 17 | 737
Waldenstrons macroglobulinemia 16 | 765
fibroadenoma 16 | 557
tuberculosis and treatment for 6 months 16 | 686
hepatocellular carcinoma 15 | 532
progressive supranuclear palsy 15 | 674
Multiple Sclerosis 14 | 498
gastric carcinoma 14 | 832
atypical teratoid/rhabdoid tumor 13 | 1,095
chronic rhinosinusitis 13 | 512
non-small cell lung carcinoma 13 | 413
Crohn's disease 12 | 304
pancreatic carcinoma 12 | 567
sarcoidosis 12 | 358
Down syndrome 11 | 548
IGA Glomerulonephritis 11 | 454
acute myeloid leukemia 11 | 780
gastric cancer 11 | 430
Atherosclerosis 10 | 275
Duchenne muscular dystrophy 10 | 602
Endometriosis 10 | 535
Obesity 10 | 616
Schizophrenia 10 | 501
nephrosclerosis 10 | 329
urothelial carcinoma 10 | 318
Alcohol dependence 9 | 107
Barrett's esophagus 9 | 183
Liver disease 9 | 219
Prostatic Neoplasms 9 | 471
cystic fibrosis and chronic rhinosinusitis 9 | 213
Alzheimer's disease 8 | 644
Asthma 8 | 349
Coronary artery disease 8 | 240
Kidney disease 8 | 396
aldosterone-producing adenoma 8 | 664
facioscapulohumeral dystrophy 8 | 286
hereditary spastic paraplegia 8 | 313
periodontitis 8 | 269
Intellectual disability 7 | 573
mucosa-associated lymphoid tissue lymphoma 7 | 480

Tissue

Liver and Pancreas 322 | 18,136
Digestive Tract 320 | 18,473
Endocrine System 319 | 18,512
Female tissues 319 | 18,647
Nervous System 318 | 18,561
Urinary Tract 318 | 18,444
Cardiovascular System 316 | 17,958
Male tissues 316 | 17,969
Blood and immune system 315 | 17,995
Skin and soft tissues 314 | 18,115
Respiratory system 312 | 17,484

Target Family

Non-IDG 178 | 11,971
Enzyme 84 | 4,146
Transcription Factor 22 | 1,400
Transporter 16 | 473
Ion Channel 8 | 341
Kinase 8 | 634
GPCR 7 | 406
Epigenetic 3 | 242
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Small intestine 327 | 327
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
N-acetylated-alpha-linked acidic dipeptidase-like protein NAALADL1 Tbio Enzyme -1.30374 25.3 78
Angiogenin ANG Tbio Enzyme -2.89794 796.0 203
Sodium/nucleoside cotransporter 2 SLC28A2 Tchem Transporter -1.78327 62.8 105
Transmembrane and coiled-coil domain-containing protein 4 TMCO4 Tdark Non-IDG 0.85 0.08 54
Putative high mobility group protein B1-like 1 HMGB1P1 Tdark Non-IDG -3.17050 1948.8 0
Lipoma-preferred partner LPP Tbio Non-IDG -2.68601 520.6 153
5-hydroxytryptamine receptor 3A HTR3A Tclin Ion Channel -3.37968 2392.4 232
5'-3' exoribonuclease 1 XRN1 Tbio Enzyme -2.06818 114.2 45
Galanin receptor type 1 GALR1 Tchem GPCR -2.03181 105.6 243
Calcium-responsive transactivator SS18L1 Tbio Non-IDG -0.76611 6.13 75