Development Level

Tbio 19 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
convulsive seizures 1 | 13
decreased caudal vertebrae num... 1 | 53
embryonic lethality prior to t... 1 | 278
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 18 | 11,493
ovarian cancer 17 | 8,520
glioblastoma 12 | 5,792
lung cancer 12 | 4,740
osteosarcoma 12 | 7,950
Breast cancer 9 | 3,578
ependymoma 9 | 4,679
medulloblastoma, large-cell 9 | 6,241
psoriasis 9 | 6,694
atypical teratoid / rhabdoid tumor 8 | 5,112
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung adenocarcinoma 8 | 2,716
ulcerative colitis 8 | 1,819
Autosomal recessive predisposition 7 | 1,442
Intellectual disability 7 | 1,016
Short stature 7 | 531
pancreatic cancer 7 | 2,398
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
malignant mesothelioma 6 | 3,232
primary pancreatic ductal adenocarcinoma 6 | 1,109
Cancer 5 | 2,499
Liver Cirrhosis, Experimental 5 | 769
Pick disease 5 | 1,894
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Astrocytoma, Pilocytic 4 | 3,081
Duchenne muscular dystrophy 4 | 601
Dull intelligence 4 | 645
Hernia, Inguinal 4 | 89
Hypertensive disease 4 | 292
Kidney cancer 4 | 2,613
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Muscle hypotonia 4 | 571
Obesity 4 | 678
Orbital separation excessive 4 | 244
Poor school performance 4 | 645
acute myeloid leukemia 4 | 783
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
diabetes mellitus 4 | 1,728
esophageal adenocarcinoma 4 | 737
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Coarse facial features 3 | 108
Cognitive delay 3 | 608
Constipation 3 | 181
Degenerative polyarthritis 3 | 115
Dyschezia 3 | 135
Epilepsy 3 | 792
Exophthalmos 3 | 112
Feeding difficulties in infancy 3 | 175
Glaucoma 3 | 239
Global developmental delay 3 | 608
Gout 3 | 106
Hypertension 3 | 396
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Osteoarthritis 3 | 184
Osteoporosis 3 | 363
Polycystic ovary syndrome 3 | 360
Prominent eyes 3 | 96
Prominent globes 3 | 96
Protruding eyes 3 | 96
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
Seizures 3 | 596
Sensorineural Hearing Loss (disorder) 3 | 284
Thickened facial skin with coarse facial features 3 | 108
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
non primary Sjogren syndrome sicca 3 | 891
pediatric high grade glioma 3 | 1,064
pterygium 3 | 76
spina bifida 3 | 1,074
Congenital anomaly of face 2 | 56
Congenital clubfoot 2 | 109
Heartburn 2 | 78
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Macrotia 2 | 87
Prominent ear 2 | 56
Protruding ears 2 | 56

Tissue

Blood and immune system 24 | 16,909
Cardiovascular System 24 | 15,192
Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Nervous System 24 | 16,725
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678

Target Family

Enzyme 9 | 4,145
Non-IDG 9 | 12,091
Kinase 3 | 634
Transcription Factor 2 | 1,400
Transporter 1 | 473

Jensen-KB Tissue

Skin fibroblast 24 | 24
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Isobutyryl-CoA dehydrogenase, mitochondrial ACAD8 Tbio Enzyme -1.14784 13.9 150
Galactocerebrosidase GALC Tbio Enzyme -2.56924 363.2 143
C-C motif chemokine 13 CCL13 Tbio Non-IDG -2.02640 99.2 264
Lysine-specific demethylase hairless HR Tbio Enzyme -1.13301 12.4 99
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.55611 364.6 174
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Elastin ELN Tbio Non-IDG -3.36288 2144.5 299
Equilibrative nucleoside transporter 3 SLC29A3 Tbio Transporter -2.44355 273.3 75
Zinc finger and BTB domain-containing protein 7B ZBTB7B Tbio Transcription Factor -1.80662 70.1 218
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ENPP1 Tchem Enzyme -2.74480 552.8 275