Development Level

Tbio 991 | 10,625
Tdark 337 | 7,003
Tchem 179 | 1,890
Tclin 41 | 602

Collection

Eligible non-olfactory GPCR Proteins 5 | 145
Eligible Ion Channel Proteins 3 | 117
Eligible Kinase Proteins 2 | 134

IMPC Term

preweaning lethality, complete... 70 | 633
abnormal behavior 32 | 226
preweaning lethality, incomple... 25 | 260
decreased lean body mass 23 | 195
embryonic lethality prior to o... 23 | 148
embryonic lethality prior to t... 23 | 187
decreased total body fat amoun... 21 | 186
decreased body length 15 | 108
decreased body weight 15 | 174
decreased bone mineral content 15 | 157
increased mean corpuscular hem... 15 | 93
decreased bone mineral density 14 | 126
decreased circulating choleste... 14 | 85
enlarged heart 13 | 111
hyperactivity 13 | 108
increased bone mineral content 13 | 92
abnormal coat/hair pigmentatio... 12 | 54
abnormal retina morphology 12 | 100
decreased circulating HDL chol... 12 | 77
abnormal embryo size 11 | 112
decreased circulating glucose ... 11 | 121
increased bone mineral density 11 | 52
increased or absent threshold ... 11 | 128
abnormal lens morphology 10 | 73
decreased grip strength 10 | 123
decreased startle reflex 10 | 48
increased circulating HDL chol... 10 | 63
increased circulating alkaline... 10 | 119
increased lean body mass 10 | 107
short tibia 10 | 82
abnormal bone structure 9 | 131
abnormal behavioral response t... 8 | 52
decreased circulating fructosa... 8 | 31
decreased circulating serum al... 8 | 79
decreased hemoglobin content 8 | 53
hypoactivity 8 | 89
increased grip strength 8 | 83
increased mean corpuscular vol... 8 | 91
prenatal lethality prior to he... 8 | 64
decreased caudal vertebrae num... 7 | 49
decreased circulating alanine ... 7 | 53
decreased circulating insulin ... 7 | 75
decreased circulating triglyce... 7 | 83
decreased heart weight 7 | 44
increased circulating choleste... 7 | 53
increased circulating phosphat... 7 | 24
abnormal gait 6 | 51
decreased erythrocyte cell num... 6 | 43
decreased fasted circulating g... 6 | 49
decreased prepulse inhibition 6 | 52
improved glucose tolerance 6 | 56
increased exploration in new e... 6 | 56
increased fasted circulating g... 6 | 68
increased total body fat amoun... 6 | 57
abnormal retinal pigmentation 5 | 61
cataract 5 | 26
decreased circulating LDL chol... 5 | 37
decreased circulating total pr... 5 | 41
decreased lumbar vertebrae num... 5 | 62
decreased rib number 5 | 59
increased gamma-delta T cell n... 5 | 16
increased sacral vertebrae num... 5 | 62
abnormal QRS complex 4 | 25
abnormal bone mineralization 4 | 55
abnormal cornea morphology 4 | 24
abnormal heart morphology 4 | 51
abnormal spleen morphology 4 | 36
abnormal tail morphology 4 | 17
decreased T cell number 4 | 31
decreased circulating aspartat... 4 | 27
decreased circulating calcium ... 4 | 33
decreased circulating chloride... 4 | 32
decreased circulating iron lev... 4 | 25
decreased circulating phosphat... 4 | 15
decreased eosinophil cell numb... 4 | 41
decreased hematocrit 4 | 25
decreased monocyte cell number 4 | 28
female infertility 4 | 34
hydrops fetalis 4 | 22
small testis 4 | 37
straub tail 4 | 26
tremors 4 | 34
abnormal coat appearance 3 | 25
abnormal epididymis morphology 3 | 31
abnormal heart left ventricle ... 3 | 20
abnormal skin coloration 3 | 18
abnormal sleep behavior 3 | 63
abnormal vocalization 3 | 21
cardiovascular system phenotyp... 3 | 35
decreased circulating potassiu... 3 | 17
decreased mean corpuscular vol... 3 | 50
decreased neutrophil cell numb... 3 | 37
enlarged spleen 3 | 26
increased body length 3 | 20
increased circulating aspartat... 3 | 17
increased circulating chloride... 3 | 43
increased circulating iron lev... 3 | 25
increased circulating sodium l... 3 | 71
increased hemoglobin content 3 | 45
vertebral fusion 3 | 23

Disease

ovarian cancer 891 | 8,492
osteosarcoma 701 | 7,933
psoriasis 563 | 6,685
medulloblastoma, large-cell 528 | 6,234
glioblastoma 515 | 5,572
lung cancer 463 | 4,473
atypical teratoid / rhabdoid tumor 328 | 4,369
malignant mesothelioma 320 | 3,163
intraductal papillary-mucinous neoplasm (IPMN) 299 | 3,289
Breast cancer 281 | 3,099
intraductal papillary-mucinous adenoma (IPMA) 266 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 261 | 2,988
invasive ductal carcinoma 251 | 2,950
oligodendroglioma 251 | 2,849
pediatric high grade glioma 249 | 2,712
primitive neuroectodermal tumor 248 | 3,031
non-small cell lung cancer 246 | 2,798
Cancer 242 | 2,346
pilocytic astrocytoma 239 | 3,086
lung adenocarcinoma 237 | 2,714
pancreatic cancer 233 | 2,300
ependymoma 219 | 2,514
Multiple myeloma 213 | 1,328
group 3 medulloblastoma 206 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 202 | 1,795
ulcerative colitis 198 | 2,087
subependymal giant cell astrocytoma 194 | 2,287
astrocytic glioma 186 | 2,241
adult high grade glioma 171 | 2,148
interstitial cystitis 168 | 2,299
Pick disease 166 | 1,893
diabetes mellitus 165 | 1,663
lung carcinoma 165 | 2,844
group 4 medulloblastoma 160 | 1,875
cystic fibrosis 159 | 1,670
astrocytoma 158 | 1,493
ductal carcinoma in situ 153 | 1,745
pituitary cancer 153 | 1,972
breast carcinoma 147 | 1,614
posterior fossa group A ependymoma 145 | 1,511
colon cancer 140 | 1,475
tuberculosis 136 | 1,563
primary pancreatic ductal adenocarcinoma 135 | 1,271
acute quadriplegic myopathy 134 | 1,157
juvenile dermatomyositis 130 | 1,189
adrenocortical carcinoma 129 | 1,427
dermatomyositis 120 | 967
Carcinoma 119 | 2,147
sonic hedgehog group medulloblastoma 113 | 1,482
Rheumatoid Arthritis 112 | 1,171
medulloblastoma 109 | 1,524
esophageal adenocarcinoma 104 | 737
Waldenstrons macroglobulinemia 101 | 765
non primary Sjogren syndrome sicca 100 | 840
Atopic dermatitis 98 | 944
atypical teratoid/rhabdoid tumor 96 | 1,095
spina bifida 96 | 1,064
gastric carcinoma 93 | 832
active Crohn's disease 87 | 918
acute myeloid leukemia 83 | 785
cutaneous lupus erythematosus 82 | 1,056
nasopharyngeal carcinoma 80 | 1,056
Duchenne muscular dystrophy 76 | 602
posterior fossa group B ependymoma 71 | 1,530
tuberculosis and treatment for 6 months 62 | 686
progressive supranuclear palsy 61 | 674
Obesity 60 | 616
hepatocellular carcinoma 59 | 550
primary Sjogren syndrome 59 | 789
Down syndrome 58 | 548
autosomal dominant Emery-Dreifuss muscular dystrophy 57 | 499
inflammatory breast cancer 56 | 404
Alzheimer's disease 54 | 644
Intellectual disability 51 | 573
aldosterone-producing adenoma 51 | 664
IGA Glomerulonephritis 50 | 454
Prostatic Neoplasms 48 | 471
Endometriosis 46 | 535
fibroadenoma 46 | 557
pancreatic carcinoma 42 | 567
active ulcerative colitis 40 | 477
Melanoma 38 | 261
Neurodegenerative disease 38 | 383
Polycystic Ovary Syndrome 37 | 335
Stomach Neoplasms 37 | 282
gastric cancer 37 | 436
Liver carcinoma 36 | 217
Mammary Neoplasms 36 | 410
Multiple Sclerosis 36 | 498
Amyotrophic Lateral Sclerosis 35 | 432
interstitial lung disease 35 | 292
Vascular disease 33 | 281
mucosa-associated lymphoid tissue lymphoma 33 | 480
Schizophrenia 32 | 503
periodontitis 31 | 269
chronic rhinosinusitis 30 | 512
Peripheral Neuropathy 29 | 303
Kidney disease 28 | 397
tuberculosis and treatment for 3 months 28 | 327
urothelial carcinoma 28 | 318

Tissue

Digestive Tract 1,532 | 18,473
Nervous System 1,532 | 18,561
Female tissues 1,531 | 18,647
Endocrine System 1,530 | 18,512
Blood and immune system 1,527 | 17,995
Urinary Tract 1,527 | 18,444
Liver and Pancreas 1,524 | 18,136
Cardiovascular System 1,523 | 17,958
Male tissues 1,523 | 17,969
Skin and soft tissues 1,521 | 18,115
Respiratory system 1,512 | 17,484

Target Family

Non-IDG 904 | 11,969
Enzyme 438 | 4,146
Transcription Factor 83 | 1,400
Kinase 43 | 634
Transporter 31 | 473
Epigenetic 25 | 242
GPCR 12 | 408
Ion Channel 9 | 341
Nuclear Receptor 3 | 48

Jensen-KB Tissue

Skin 1,548 | 1,548
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Prostate gland epithelium 456 | 456
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GPI mannosyltransferase 4 PIGZ Tdark Enzyme -1.17375 14.4 26
Solute carrier family 25 member 33 SLC25A33 Tbio Transporter -0.28165 1.49 35
Psoriasis susceptibility 1 candidate gene 2 protein PSORS1C2 Tbio Non-IDG -1.03330 10.2 12
E3 ubiquitin-protein ligase RNF115 RNF115 Tbio Enzyme -1.29757 20.6 76
Zinc finger protein 577 ZNF577 Tdark Transcription Factor -0.21748 0.65 44
Latexin LXN Tbio Enzyme -2.51597 319.1 359
MRG/MORF4L-binding protein MRGBP Tbio Non-IDG -0.60412 4.30 131
Lipopolysaccharide-induced tumor necrosis factor-alpha factor LITAF Tbio Transcription Factor -2.00894 100.6 155
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 Tbio Enzyme -2.08075 121.5 75
5'-nucleotidase domain-containing protein 3 NT5DC3 Tdark Enzyme -1.72530 52.1 19