Development Level

Tbio 406 | 11,445
Tdark 74 | 6,588
Tchem 53 | 1,598
Tclin 16 | 613

Collection

Kinase: IDG Consortium (Target... 5 | 125
Ion Channel: IDG Consortium (T... 4 | 99

IMPC Phenotype

preweaning lethality, complete... 40 | 979
abnormal embryo size 11 | 220
abnormal bone structure 9 | 187
decreased vertical activity 9 | 208
embryonic lethality prior to t... 9 | 278
preweaning lethality, incomple... 9 | 499
decreased circulating glucose ... 8 | 126
edema 7 | 59
embryonic lethality prior to o... 7 | 239
decreased body weight 6 | 161
decreased fasted circulating g... 6 | 65
increased bone mineral content 6 | 108
abnormal behavior 5 | 298
abnormal sleep behavior 5 | 70
decreased bone mineral density 5 | 126
decreased lean body mass 5 | 135
decreased prepulse inhibition 5 | 82
decreased total body fat amoun... 5 | 207
increased or absent threshold ... 5 | 101
abnormal limb bud morphology 4 | 17
abnormal vocalization 4 | 21
decreased bone mineral content 4 | 151
decreased circulating creatini... 4 | 39
decreased grip strength 4 | 116
decreased leukocyte cell numbe... 4 | 73
enlarged heart 4 | 210
hyperactivity 4 | 148
impaired glucose tolerance 4 | 75
increased circulating alkaline... 4 | 122
increased circulating choleste... 4 | 66
increased hematocrit 4 | 46
increased total body fat amoun... 4 | 134
small testis 4 | 58
abnormal craniofacial morpholo... 3 | 33
abnormal facial morphology 3 | 17
abnormal neural tube closure 3 | 46
decreased circulating alkaline... 3 | 46
decreased circulating choleste... 3 | 93
decreased circulating total pr... 3 | 49
embryonic growth retardation 3 | 106
increased body length 3 | 32
increased hemoglobin content 3 | 45
increased lean body mass 3 | 172
increased leukocyte cell numbe... 3 | 47
increased mean corpuscular hem... 3 | 96
increased startle reflex 3 | 112
pallor 3 | 34
prenatal lethality 3 | 28
shortened RR interval 3 | 17
abnormal behavioral response t... 2 | 66
abnormal body wall morphology 2 | 9
abnormal coat-hair pigmentatio... 2 | 64
abnormal embryo turning 2 | 31
abnormal heart morphology 2 | 162
abnormal joint morphology 2 | 23
abnormal kidney morphology 2 | 65
abnormal lens morphology 2 | 81
abnormal limb morphology 2 | 13
abnormal placenta size 2 | 20
abnormal retinal vasculature m... 2 | 27
abnormal seminal vesicle morph... 2 | 114
abnormal skin coloration 2 | 25
abnormal vibrissa morphology 2 | 25
anophthalmia 2 | 33
brachydactyly 2 | 19
cataract 2 | 92
cleft palate 2 | 8
decreased body length 2 | 101
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased erythrocyte cell num... 2 | 62
decreased lymphocyte cell numb... 2 | 83
decreased mean platelet volume 2 | 25
decreased neutrophil cell numb... 2 | 42
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
enlarged lymph nodes 2 | 37
enlarged spleen 2 | 41
facial cleft 2 | 3
hemorrhage 2 | 23
hydrometra 2 | 53
increased blood urea nitrogen ... 2 | 48
increased body weight 2 | 25
increased caudal vertebrae num... 2 | 7
increased circulating iron lev... 2 | 30
increased circulating serum al... 2 | 22
increased circulating total pr... 2 | 28
increased erythrocyte cell num... 2 | 39
increased heart rate 2 | 23
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
persistence of hyaloid vascula... 2 | 33
polydactyly 2 | 7
syndactyly 2 | 23
thrombocytopenia 2 | 56
tremors 2 | 39
decreased T cell number 1 | 15
decreased circulating amylase ... 1 | 28
decreased total retina thickne... 1 | 17
thin ventricular wall 1 | 24

Disease

Carcinoma 318 | 11,493
ovarian cancer 281 | 8,520
osteosarcoma 231 | 7,950
psoriasis 210 | 6,694
medulloblastoma, large-cell 187 | 6,241
glioblastoma 177 | 5,792
atypical teratoid / rhabdoid tumor 165 | 5,112
lung cancer 151 | 4,740
group 3 medulloblastoma 142 | 4,104
ependymoma 140 | 4,679
Breast cancer 136 | 3,578
adult high grade glioma 114 | 3,801
Kidney cancer 112 | 2,613
invasive ductal carcinoma 106 | 2,951
non-small cell lung cancer 105 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 104 | 3,291
primitive neuroectodermal tumor 101 | 3,035
acute quadriplegic myopathy 97 | 1,158
lung adenocarcinoma 97 | 2,716
malignant mesothelioma 96 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 95 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 95 | 2,989
Astrocytoma, Pilocytic 93 | 3,081
astrocytic glioma 89 | 2,597
oligodendroglioma 81 | 2,850
lung carcinoma 80 | 2,843
pancreatic cancer 80 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 76 | 1,962
Autosomal recessive predisposition 75 | 1,442
ductal carcinoma in situ 75 | 1,745
pituitary cancer 71 | 1,972
Multiple myeloma 69 | 1,332
breast carcinoma 64 | 1,638
diabetes mellitus 63 | 1,728
Cancer 62 | 2,499
subependymal giant cell astrocytoma 62 | 2,287
Pick disease 58 | 1,894
colon cancer 58 | 1,478
dermatomyositis 57 | 966
group 4 medulloblastoma 56 | 1,855
cystic fibrosis 53 | 1,696
interstitial cystitis 53 | 2,312
tuberculosis 53 | 2,010
ulcerative colitis 50 | 1,819
adrenocortical carcinoma 49 | 1,428
Duchenne muscular dystrophy 46 | 601
juvenile dermatomyositis 46 | 1,187
Myopathy 43 | 185
spina bifida 40 | 1,074
Rheumatoid arthritis 38 | 1,191
pediatric high grade glioma 38 | 1,064
primary pancreatic ductal adenocarcinoma 37 | 1,109
Waldenstrons macroglobulinemia 36 | 765
astrocytoma 35 | 1,146
Epilepsy 34 | 792
Intellectual disability 33 | 1,016
Liver Cirrhosis, Experimental 33 | 769
Melanoma 31 | 711
Muscle hypotonia 31 | 571
Obesity 31 | 678
hereditary spastic paraplegia 31 | 318
Schizophrenia 30 | 1,160
Heart disease 28 | 306
cutaneous lupus erythematosus 28 | 1,057
non primary Sjogren syndrome sicca 28 | 891
esophageal adenocarcinoma 27 | 737
gastric carcinoma 27 | 807
Amyotrophic lateral sclerosis 26 | 451
Atopic dermatitis 26 | 952
Cognitive delay 26 | 608
Dull intelligence 26 | 645
Global developmental delay 26 | 608
Low intelligence 26 | 645
Mental Retardation 26 | 645
Mental and motor retardation 26 | 608
Mental deficiency 26 | 645
Poor school performance 26 | 645
Seizures 26 | 596
Skin cancer 26 | 469
Liver cancer 25 | 604
aldosterone-producing adenoma 25 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 25 | 510
active ulcerative colitis 24 | 764
fibroadenoma 24 | 559
progressive supranuclear palsy 24 | 676
nasopharyngeal carcinoma 23 | 1,058
Hypertrophic Cardiomyopathy 22 | 117
Alzheimer's disease 21 | 658
Cardiomyopathy 21 | 116
Creatine phosphokinase serum increased 21 | 110
Elevated creatine kinase 21 | 110
active Crohn's disease 21 | 922
acute myeloid leukemia 21 | 783
limb girdle muscular dystrophy 2A 21 | 213
medulloblastoma 21 | 720
Acquired scoliosis 20 | 281
Cardiomyopathy, Dilated 20 | 83
Curvature of spine 20 | 282
Endometrial cancer 20 | 311
Coronary artery disease 19 | 268

Tissue

Digestive Tract 542 | 17,369
Skin and soft tissues 542 | 17,230
Endocrine System 540 | 18,159
Male tissues 536 | 17,142
Female tissues 529 | 17,400
Urinary Tract 523 | 16,678
Blood and immune system 520 | 16,909
Cardiovascular System 519 | 15,192
Liver and Pancreas 519 | 16,750
Nervous System 516 | 16,725
Respiratory system 505 | 16,393

Target Family

Non-IDG 339 | 12,091
Enzyme 118 | 4,145
Kinase 22 | 634
Transcription Factor 21 | 1,400
Transporter 20 | 473
Ion Channel 15 | 344
Epigenetic 7 | 242
Nuclear Receptor 5 | 48
GPCR 1 | 408
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Skeletal muscle 549 | 549
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
Ankyrin repeat and SOCS box protein 5 ASB5 Tdark Non-IDG 0.03 1.06 75
Myomesin-1 MYOM1 Tbio Non-IDG -1.21420 16.8 127
Tubulin alpha-8 chain TUBA8 Tbio Non-IDG -0.87821 7.61 118
Electrogenic sodium bicarbonate cotransporter 1 SLC4A4 Tbio Transporter -2.63743 436.2 124
Mitogen-activated protein kinase kinase kinase 4 MAP3K4 Tbio Kinase -1.49704 31.8 244
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial MCCC1 Tbio Enzyme -1.91194 82.4 102
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Ankyrin repeat and SOCS box protein 12 ASB12 Tdark Non-IDG 0.00000 52