Development Level

Tbio 60 | 11,445
Tdark 9 | 6,588
Tchem 5 | 1,598

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

decreased body weight 3 | 161
hyperactivity 3 | 148
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased mean corpuscular hem... 2 | 50
decreased total body fat amoun... 2 | 207
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
cataract 1 | 92
decreased anxiety-related resp... 1 | 12
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased heart left ventricle... 1 | 28
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hemorrhage 1 | 23
increased bone mineral content 1 | 108
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
increased vertical activity 1 | 24
tremors 1 | 39

Disease

Carcinoma 58 | 11,493
ovarian cancer 46 | 8,520
osteosarcoma 42 | 7,950
psoriasis 28 | 6,694
glioblastoma 24 | 5,792
medulloblastoma, large-cell 24 | 6,241
ependymoma 23 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
atypical teratoid / rhabdoid tumor 21 | 5,112
lung cancer 21 | 4,740
invasive ductal carcinoma 18 | 2,951
Kidney cancer 17 | 2,613
adult high grade glioma 17 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
malignant mesothelioma 15 | 3,232
lung adenocarcinoma 13 | 2,716
oligodendroglioma 13 | 2,850
Astrocytoma, Pilocytic 12 | 3,081
group 3 medulloblastoma 12 | 4,104
group 4 medulloblastoma 12 | 1,855
primitive neuroectodermal tumor 12 | 3,035
Breast cancer 11 | 3,578
Cancer 11 | 2,499
astrocytic glioma 11 | 2,597
cutaneous lupus erythematosus 11 | 1,057
cystic fibrosis 11 | 1,696
interstitial cystitis 11 | 2,312
pituitary cancer 11 | 1,972
subependymal giant cell astrocytoma 11 | 2,287
non-small cell lung cancer 10 | 2,890
ductal carcinoma in situ 9 | 1,745
pancreatic cancer 9 | 2,398
Pick disease 8 | 1,894
acute quadriplegic myopathy 8 | 1,158
breast carcinoma 8 | 1,638
lung carcinoma 8 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Schizophrenia 7 | 1,160
astrocytoma 7 | 1,146
spina bifida 7 | 1,074
tuberculosis 7 | 2,010
Autosomal recessive predisposition 6 | 1,442
Multiple myeloma 6 | 1,332
Rheumatoid arthritis 6 | 1,191
active Crohn's disease 6 | 922
colon cancer 6 | 1,478
Liver cancer 5 | 604
active ulcerative colitis 5 | 764
aldosterone-producing adenoma 5 | 665
dermatomyositis 5 | 966
nasopharyngeal carcinoma 5 | 1,058
primary pancreatic ductal adenocarcinoma 5 | 1,109
progressive supranuclear palsy 5 | 676
ulcerative colitis 5 | 1,819
Atopic dermatitis 4 | 952
Down syndrome 4 | 499
Infertility 4 | 188
Waldenstrons macroglobulinemia 4 | 765
adrenocortical carcinoma 4 | 1,428
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
non primary Sjogren syndrome sicca 4 | 891
sonic hedgehog group medulloblastoma 4 | 467
Acquired metabolic disease 3 | 336
Amyotrophic lateral sclerosis 3 | 451
Cognitive delay 3 | 608
Duchenne muscular dystrophy 3 | 601
Endometrial cancer 3 | 311
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Kidney disease 3 | 430
Mental and motor retardation 3 | 608
Prostatic Neoplasms 3 | 495
Small head 3 | 374
acute myeloid leukemia 3 | 783
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
Adenoma 2 | 167
Aggressive behavior 2 | 75
Alzheimer's disease 2 | 658
Attention deficit hyperactivity disorder 2 | 278
Cholestasis 2 | 155
Chronic obstructive pulmonary disease 2 | 184
Depressive disorder 2 | 409
Endometriosis 2 | 540
Epilepsy 2 | 792
Hepatomegaly 2 | 285
Male infertility 2 | 206
Seizures 2 | 596
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
glioblastoma multiforme 2 | 142
mucosa-associated lymphoid tissue lymphoma 2 | 484
pediatric high grade glioma 2 | 1,064
urothelial carcinoma 2 | 318

Tissue

Endocrine System 73 | 18,159
Skin and soft tissues 73 | 17,230
Digestive Tract 72 | 17,369
Female tissues 72 | 17,400
Liver and Pancreas 72 | 16,750
Blood and immune system 70 | 16,909
Respiratory system 70 | 16,393
Urinary Tract 70 | 16,678
Cardiovascular System 69 | 15,192
Male tissues 69 | 17,142
Nervous System 68 | 16,725

Target Family

Non-IDG 43 | 12,091
Enzyme 14 | 4,145
Transcription Factor 8 | 1,400
Epigenetic 4 | 242
Transporter 3 | 473
Kinase 2 | 634

Jensen-KB Tissue

Salivary gland 74 | 74
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase SHPRH SHPRH Tbio Epigenetic -0.99196 10.7 137
Telomerase protein component 1 TEP1 Tbio Enzyme -1.74492 50.6 71
Lysine-specific demethylase 3A KDM3A Tchem Epigenetic -1.83544 74.7 253
Homeobox protein Meis3 MEIS3 Tbio Transcription Factor -0.89952 8.38 256
Mucin-5B MUC5B Tbio Non-IDG -3.20322 1552.2 177
Centrosomal protein of 120 kDa CEP120 Tbio Non-IDG -0.93215 7.32 49
POU domain, class 6, transcription factor 1 POU6F1 Tbio Transcription Factor -1.33252 21.4 205
GDP-D-glucose phosphorylase 1 GDPGP1 Tbio Enzyme -0.94612 9.60 37
Protein NOXP20 FAM114A1 Tdark Non-IDG -0.21560 1.63 25
Membrane cofactor protein CD46 Tbio Non-IDG -2.94025 875.6 770