Development Level

Tbio 63 | 11,651
Tdark 17 | 6,593
Tchem 4 | 1,388

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

embryonic lethality prior to t... 3 | 278
preweaning lethality, complete... 3 | 979
abnormal embryo size 2 | 220
decreased lymphocyte cell numb... 2 | 83
enlarged heart 2 | 210
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal sensory capabilities-... 1 | 8
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating glycerol... 1 | 16
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytosis 1 | 27
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 50 | 11,493
ovarian cancer 40 | 8,520
medulloblastoma, large-cell 37 | 6,241
osteosarcoma 34 | 7,950
atypical teratoid / rhabdoid tumor 28 | 5,112
glioblastoma 28 | 5,792
psoriasis 28 | 6,694
ependymoma 27 | 4,679
group 3 medulloblastoma 27 | 4,104
lung cancer 27 | 4,740
primitive neuroectodermal tumor 19 | 3,035
adult high grade glioma 17 | 3,801
oligodendroglioma 17 | 2,850
lung adenocarcinoma 15 | 2,716
Astrocytoma, Pilocytic 14 | 3,081
Breast cancer 14 | 3,578
malignant mesothelioma 14 | 3,232
non-small cell lung cancer 14 | 2,890
Kidney cancer 13 | 2,613
astrocytic glioma 13 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
invasive ductal carcinoma 12 | 2,951
Autosomal recessive predisposition 11 | 1,442
pancreatic cancer 11 | 2,398
Cancer 10 | 2,499
Pick disease 9 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung carcinoma 9 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
pituitary cancer 9 | 1,972
subependymal giant cell astrocytoma 9 | 2,287
tuberculosis 9 | 2,010
Intellectual disability 8 | 1,016
Retinitis Pigmentosa 8 | 226
adrenocortical carcinoma 8 | 1,428
ductal carcinoma in situ 8 | 1,745
Abnormality of retinal pigmentation 7 | 111
Difficulties with night vision 7 | 87
Keratoconus 7 | 113
Night Blindness 7 | 101
Nystagmus 7 | 317
Photodysphoria 7 | 121
Photophobia 7 | 121
Retinal pigment epithelial abnormality 7 | 111
breast carcinoma 7 | 1,638
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
nasopharyngeal carcinoma 7 | 1,058
ulcerative colitis 7 | 1,819
Cataract 6 | 297
Dull intelligence 6 | 645
Electroretinogram abnormal 6 | 95
Endometriosis 6 | 540
Glaucoma 6 | 239
Lens Opacities 6 | 231
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Multiple myeloma 6 | 1,332
Obesity 6 | 678
Poor school performance 6 | 645
Abnormality of the retinal vasculature 5 | 59
Alzheimer's disease 5 | 658
Anteverted nostril 5 | 191
Atopic dermatitis 5 | 952
Atypical scarring of skin 5 | 62
Blind Vision 5 | 111
Blindness, Legal 5 | 110
Broad flat nasal bridge 5 | 236
Conductive hearing loss 5 | 123
Congenital anomaly of testis 5 | 52
Congenital hypoplasia of penis 5 | 176
Hyperinsulinism 5 | 133
Hypogonadism 5 | 173
Liver cancer 5 | 604
Nasal bridge wide 5 | 236
Night blindness, progressive 5 | 51
Ophthalmoplegia 5 | 106
Optic Atrophy 5 | 242
Retinal Degeneration 5 | 106
Sensorineural Hearing Loss (disorder) 5 | 284
acute myeloid leukemia 5 | 783
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
dermatomyositis 5 | 966
pediatric high grade glioma 5 | 1,064
Epilepsy 4 | 792
Melanoma 4 | 711
Reduced visual acuity 4 | 63
cone-rod dystrophy 4 | 59
juvenile dermatomyositis 4 | 1,187
primary Sjogren syndrome 4 | 735
Schizophrenia 3 | 1,160
acute quadriplegic myopathy 3 | 1,158
chronic rhinosinusitis 3 | 512
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
esophageal adenocarcinoma 3 | 737
spina bifida 3 | 1,074

Tissue

Digestive Tract 82 | 17,369
Endocrine System 82 | 18,159
Male tissues 82 | 17,142
Nervous System 81 | 16,725
Skin and soft tissues 81 | 17,230
Respiratory system 80 | 16,393
Female tissues 79 | 17,400
Liver and Pancreas 79 | 16,750
Blood and immune system 78 | 16,909
Urinary Tract 77 | 16,678
Cardiovascular System 72 | 15,192

Target Family

Non-IDG 51 | 12,091
Enzyme 19 | 4,145
Transcription Factor 5 | 1,400
Epigenetic 3 | 242
Kinase 2 | 634
Transporter 2 | 473
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Retinoblastoma cell 84 | 84
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase MAK MAK Tchem Kinase -1.20155 15.2 266
Centrosomal protein of 83 kDa CEP83 Tdark Non-IDG -0.47180 2.89 0
Secretogranin-3 SCG3 Tbio Non-IDG -1.59072 42.1 169
Protein phosphatase 1 regulatory subunit 3B PPP1R3B Tbio Enzyme -2.49697 300.9 94
U4/U6 small nuclear ribonucleoprotein Prp31 PRPF31 Tbio Non-IDG -1.84397 72.4 216
Vasculin GPBP1 Tdark Non-IDG -0.50909 2.70 62
Band 4.1-like protein 5 EPB41L5 Tbio Non-IDG -1.31136 21.8 109
Tumor protein D54 TPD52L2 Tbio Non-IDG -1.84480 69.0 150
CDK5 regulatory subunit-associated protein 1 CDK5RAP1 Tbio Non-IDG -1.30040 19.0 133
Spermatid perinuclear RNA-binding protein STRBP Tdark Non-IDG -1.84543 68.4 48