Development Level

Tbio 50 | 11,445
Tchem 10 | 1,598
Tdark 7 | 6,588
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased total body fat amoun... 4 | 207
increased bone mineral content 3 | 108
increased lean body mass 3 | 172
abnormal retina morphology 2 | 71
absent pinna reflex 2 | 23
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal snout morphology 1 | 23
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
small adrenal glands 1 | 16
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 53 | 11,493
ovarian cancer 47 | 8,520
osteosarcoma 37 | 7,950
psoriasis 33 | 6,694
medulloblastoma, large-cell 27 | 6,241
glioblastoma 24 | 5,792
Cancer 22 | 2,499
lung cancer 22 | 4,740
atypical teratoid / rhabdoid tumor 20 | 5,112
group 3 medulloblastoma 20 | 4,104
ependymoma 16 | 4,679
Breast cancer 15 | 3,578
Kidney cancer 15 | 2,613
adult high grade glioma 15 | 3,801
pancreatic cancer 15 | 2,398
dermatomyositis 13 | 966
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
invasive ductal carcinoma 13 | 2,951
malignant mesothelioma 13 | 3,232
Astrocytoma, Pilocytic 12 | 3,081
Multiple myeloma 12 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Autosomal recessive predisposition 11 | 1,442
breast carcinoma 11 | 1,638
oligodendroglioma 11 | 2,850
Pick disease 10 | 1,894
Rheumatoid arthritis 10 | 1,191
Waldenstrons macroglobulinemia 10 | 765
astrocytic glioma 10 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
non-small cell lung cancer 10 | 2,890
tuberculosis 10 | 2,010
acute quadriplegic myopathy 9 | 1,158
colon cancer 9 | 1,478
lung carcinoma 9 | 2,843
Intellectual disability 8 | 1,016
Neurodegenerative disease 8 | 414
primary pancreatic ductal adenocarcinoma 8 | 1,109
ulcerative colitis 8 | 1,819
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Lung Neoplasms 7 | 232
Mental and motor retardation 7 | 608
astrocytoma 7 | 1,146
diabetes mellitus 7 | 1,728
group 4 medulloblastoma 7 | 1,855
juvenile dermatomyositis 7 | 1,187
pediatric high grade glioma 7 | 1,064
pituitary cancer 7 | 1,972
subependymal giant cell astrocytoma 7 | 2,287
Breast Neoplasms 6 | 445
Down syndrome 6 | 499
Dull intelligence 6 | 645
Failure to gain weight 6 | 365
Low intelligence 6 | 645
Mammary Neoplasms 6 | 425
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Pediatric failure to thrive 6 | 365
Poor school performance 6 | 645
cystic fibrosis 6 | 1,696
gastric carcinoma 6 | 807
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
non primary Sjogren syndrome sicca 6 | 891
Bipolar Disorder 5 | 666
Creatine phosphokinase serum increased 5 | 110
Elevated creatine kinase 5 | 110
Liver Cirrhosis, Experimental 5 | 769
Muscle hypotonia 5 | 571
Obesity 5 | 678
Sensorineural Hearing Loss (disorder) 5 | 284
Short stature 5 | 531
adrenocortical carcinoma 5 | 1,428
progressive supranuclear palsy 5 | 676
Alzheimer's disease 4 | 658
Cerebral atrophy 4 | 178
Isolated cases 4 | 72
Major Depressive Disorder 4 | 301
Multiple Sclerosis 4 | 540
Neuropathy 4 | 261
Nystagmus 4 | 317
Patent ductus arteriosus 4 | 90
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
Small head 4 | 374
Strabismus 4 | 270
Unipolar Depression 4 | 250
Vascular disease 4 | 319
active ulcerative colitis 4 | 764
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
chronic rhinosinusitis 4 | 512
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
fibroadenoma 4 | 559
nephrosclerosis 4 | 333
pancreatic carcinoma 4 | 562
primitive neuroectodermal tumor 4 | 3,035

Tissue

Digestive Tract 68 | 17,369
Endocrine System 68 | 18,159
Female tissues 68 | 17,400
Liver and Pancreas 68 | 16,750
Male tissues 68 | 17,142
Nervous System 68 | 16,725
Respiratory system 68 | 16,393
Skin and soft tissues 68 | 17,230
Urinary Tract 68 | 16,678
Blood and immune system 67 | 16,909
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 44 | 12,091
Enzyme 17 | 4,145
Kinase 7 | 634
Epigenetic 2 | 242
Transcription Factor 2 | 1,400

Jensen-KB Tissue

Renal cell carcinoma cell 72 | 72
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 608 ZNF608 Tdark Non-IDG -0.47998 2.60 62
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.85307 72.5 189
Cactin CACTIN Tbio Non-IDG -1.26544 19.0 50
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 PTPMT1 Tbio Enzyme -1.36243 23.0 109
Alanine--tRNA ligase, cytoplasmic AARS Tbio Enzyme -2.49617 295.2 140
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
GRIP and coiled-coil domain-containing protein 2 GCC2 Tbio Non-IDG -1.05613 12.1 143
Serine/threonine-protein kinase Nek1 NEK1 Tchem Kinase -1.62443 47.0 85
YTH domain-containing family protein 2 YTHDF2 Tbio Non-IDG -1.37929 18.0 88