Development Level

Tbio 275 | 10,625
Tdark 104 | 7,003
Tchem 60 | 1,890
Tclin 17 | 602

Collection

Eligible Kinase Proteins 2 | 134
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 14 | 633
decreased grip strength 6 | 123
abnormal behavior 5 | 226
decreased body weight 5 | 174
preweaning lethality, incomple... 5 | 260
cardiovascular system phenotyp... 4 | 35
decreased bone mineral content 4 | 157
decreased circulating glucose ... 4 | 121
decreased lean body mass 4 | 195
decreased total body fat amoun... 4 | 186
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 4 | 187
enlarged heart 4 | 111
increased or absent threshold ... 4 | 128
increased sacral vertebrae num... 4 | 62
abnormal bone structure 3 | 131
abnormal retina morphology 3 | 100
decreased circulating triglyce... 3 | 83
decreased erythrocyte cell num... 3 | 43
decreased lumbar vertebrae num... 3 | 62
decreased startle reflex 3 | 48
hypoactivity 3 | 89
increased mean corpuscular vol... 3 | 91
abnormal cornea morphology 2 | 24
abnormal embryo size 2 | 112
abnormal iris morphology 2 | 12
abnormal lens morphology 2 | 73
decreased body length 2 | 108
decreased caudal vertebrae num... 2 | 49
decreased circulating HDL chol... 2 | 77
decreased circulating choleste... 2 | 85
decreased circulating free fat... 2 | 39
decreased circulating fructosa... 2 | 31
decreased circulating insulin ... 2 | 75
decreased circulating serum al... 2 | 79
decreased circulating total pr... 2 | 41
decreased heart rate variabili... 2 | 11
decreased hematocrit 2 | 25
decreased hemoglobin content 2 | 53
decreased leukocyte cell numbe... 2 | 54
decreased rib number 2 | 59
decreased threshold for audito... 2 | 32
hydrometra 2 | 13
increased bone mineral content 2 | 92
increased circulating alkaline... 2 | 119
increased circulating aspartat... 2 | 17
increased circulating calcium ... 2 | 32
increased circulating choleste... 2 | 53
increased circulating sodium l... 2 | 71
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 93
increased mean corpuscular hem... 2 | 25
irregularly shaped pupil 2 | 7
small liver 2 | 8
abnormal coping response 1 | 12
abnormal heart morphology 1 | 51
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal placenta morphology 1 | 4
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal tail movements 1 | 12
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
absent pinna reflex 1 | 21
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased Ly6C high monocyte n... 1 | 18
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 5
decreased circulating potassiu... 1 | 17
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased total retina thickne... 1 | 20
dilated heart left ventricle 1 | 10
embryonic growth retardation 1 | 28
enlarged spleen 1 | 26
hydrops fetalis 1 | 22
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased blood uric acid leve... 1 | 5
increased circulating HDL chol... 1 | 63
increased circulating iron lev... 1 | 25
increased effector memory CD4-... 1 | 15
increased grip strength 1 | 83
increased startle reflex 1 | 38
oligodactyly 1 | 14
prolonged PR interval 1 | 4
small thymus 1 | 11
straub tail 1 | 26
trunk curl 1 | 15
vertebral fusion 1 | 23

Disease

ovarian cancer 233 | 8,484
osteosarcoma 208 | 7,933
psoriasis 168 | 6,685
medulloblastoma, large-cell 161 | 6,234
glioblastoma 139 | 5,572
lung cancer 137 | 4,466
Breast cancer 115 | 3,094
atypical teratoid / rhabdoid tumor 112 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 105 | 3,289
invasive ductal carcinoma 100 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 99 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 99 | 2,988
interstitial cystitis 96 | 2,299
lung carcinoma 93 | 2,844
pancreatic cancer 89 | 2,300
non-small cell lung cancer 88 | 2,798
lung adenocarcinoma 85 | 2,713
malignant mesothelioma 80 | 3,162
pilocytic astrocytoma 78 | 3,086
oligodendroglioma 75 | 2,849
primitive neuroectodermal tumor 72 | 3,031
cystic fibrosis 71 | 1,665
Cancer 70 | 2,346
pediatric high grade glioma 70 | 2,712
ulcerative colitis 68 | 2,087
group 3 medulloblastoma 64 | 2,254
ductal carcinoma in situ 62 | 1,745
ependymoma 62 | 2,514
astrocytic glioma 61 | 2,241
colon cancer 56 | 1,475
pituitary cancer 56 | 1,972
subependymal giant cell astrocytoma 53 | 2,287
tuberculosis 53 | 1,557
astrocytoma 52 | 1,493
breast carcinoma 52 | 1,614
Pick disease 50 | 1,893
pancreatic ductal adenocarcinoma liver metastasis 49 | 1,795
Multiple myeloma 48 | 1,327
adult high grade glioma 48 | 2,148
Carcinoma 47 | 2,147
acute quadriplegic myopathy 46 | 1,157
primary pancreatic ductal adenocarcinoma 45 | 1,271
medulloblastoma 42 | 1,524
spina bifida 40 | 1,064
group 4 medulloblastoma 39 | 1,875
juvenile dermatomyositis 39 | 1,189
diabetes mellitus 36 | 1,663
adrenocortical carcinoma 35 | 1,427
posterior fossa group A ependymoma 34 | 1,511
posterior fossa group B ependymoma 34 | 1,530
dermatomyositis 33 | 933
active Crohn's disease 32 | 918
sonic hedgehog group medulloblastoma 31 | 1,482
Endometriosis 29 | 535
acute myeloid leukemia 29 | 780
Rheumatoid Arthritis 28 | 1,160
Prostatic Neoplasms 27 | 471
nasopharyngeal carcinoma 27 | 1,056
Atopic dermatitis 26 | 944
non primary Sjogren syndrome sicca 26 | 840
gastric carcinoma 25 | 832
pancreatic carcinoma 25 | 567
cutaneous lupus erythematosus 24 | 1,056
esophageal adenocarcinoma 24 | 737
Waldenstrons macroglobulinemia 23 | 765
atypical teratoid/rhabdoid tumor 23 | 1,095
fibroadenoma 22 | 557
primary Sjogren syndrome 21 | 789
progressive supranuclear palsy 21 | 674
Alzheimer's disease 20 | 644
aldosterone-producing adenoma 20 | 664
Duchenne muscular dystrophy 19 | 602
active ulcerative colitis 18 | 477
Prostate cancer 17 | 172
tuberculosis and treatment for 6 months 17 | 686
Amyotrophic Lateral Sclerosis 16 | 431
IGA Glomerulonephritis 16 | 454
Kidney disease 16 | 396
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 499
Multiple Sclerosis 15 | 498
chronic rhinosinusitis 15 | 512
gastric cancer 15 | 430
hepatocellular carcinoma 15 | 532
inflammatory breast cancer 15 | 404
Asthma 14 | 349
Hypertension 14 | 287
Mammary Neoplasms 14 | 410
Parkinson's disease 14 | 364
Polycystic Ovary Syndrome 14 | 332
sarcoidosis 14 | 358
Down syndrome 13 | 548
head and neck cancer and chronic obstructive pulmonary disease 13 | 237
hereditary spastic paraplegia 13 | 313
tuberculosis and treatment for 3 months 13 | 327
Arthritis 11 | 248
Cerebrovascular disease 11 | 231
Coronary artery disease 11 | 240
Obesity 11 | 616
Schizophrenia 11 | 501
nephrosclerosis 11 | 329

Tissue

Female tissues 451 | 18,647
Digestive Tract 450 | 18,473
Male tissues 450 | 17,969
Blood and immune system 448 | 17,995
Liver and Pancreas 448 | 18,136
Nervous System 448 | 18,561
Cardiovascular System 447 | 17,958
Urinary Tract 447 | 18,444
Endocrine System 446 | 18,512
Skin and soft tissues 443 | 18,115
Respiratory system 441 | 17,484

Target Family

Non-IDG 254 | 11,971
Enzyme 117 | 4,146
Transcription Factor 32 | 1,400
Transporter 15 | 473
Kinase 12 | 634
GPCR 9 | 406
Epigenetic 5 | 242
Ion Channel 5 | 341
Nuclear Receptor 4 | 48
oGPCR 2 | 421
TF/Epigenetic 1 | 38

Jensen-KB Tissue

Prostate gland epithelium 456 | 456
Brain 7,308 | 7,308
Liver 4,988 | 4,988
Cervical carcinoma cell 4,915 | 4,915
Erythroleukemia cell 4,274 | 4,274
Testis 3,862 | 3,862
Placenta 3,062 | 3,062
T-cell chronic lymphocytic leu... 2,337 | 2,337
Lung 2,282 | 2,282
Skin 1,548 | 1,548
Uterus 1,472 | 1,472
Kidney 1,293 | 1,293
Colon 1,061 | 1,061
Eye 852 | 852
Pancreas 828 | 828
Muscle 721 | 721
Pronephros 715 | 715
Cerebellum 693 | 693
Ovary 690 | 690
Bone marrow 633 | 633
Amygdala 622 | 622
Spleen 617 | 617
Teratocarcinoma cell 600 | 600
Heart 582 | 582
Blood 570 | 570
Colonic cancer cell 562 | 562
Lymph 562 | 562
Skeletal muscle 543 | 543
Blood platelet 539 | 539
Hippocampus 528 | 528
Trachea 519 | 519
Tongue 466 | 466
Thymus 425 | 425
Mammary gland 415 | 415
Uterine cervix 414 | 414
Melanoma cell line 363 | 363
BTO:0000379 353 | 353
Umbilical cord blood 343 | 343
Retina 334 | 334
Thalamus 330 | 330
Small intestine 327 | 327
Plasma cell 286 | 286
T-lymphocyte 284 | 284
B-lymphocyte cell line 273 | 273
Hepatoma cell 242 | 242
Urinary bladder 226 | 226
Breast cancer cell 219 | 219
Brain cortex cell line 216 | 216
Leukocyte 205 | 205
CL-48 cell 198 | 198
Interstitial cell of Cajal 193 | 193
Neuroblastoma cell 187 | 187
Peripheral nervous system 183 | 183
Ovary cancer cell 181 | 181
Stomach 179 | 179
Adrenal gland 176 | 176
Cerebral cortex 159 | 159
Lymph node 148 | 148
Synovium 147 | 147
Thyroid gland 144 | 144
Keratinocyte 140 | 140
Fibroblast 139 | 139
Adipose tissue 136 | 136
Duodenum 135 | 135
Peripheral blood 135 | 135
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 116 | 116
Subthalamic nucleus 111 | 111
Caudate nucleus 109 | 109
Lung cancer cell 104 | 104
Prostate cancer cell line 90 | 90
Lymphocyte 86 | 86
Aorta 84 | 84
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 76 | 76
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 73 | 73
Renal cell carcinoma cell 72 | 72
Substantia nigra 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Hair root 55 | 55
Colonic mucosa 54 | 54
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.31593 2169.0 108
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Tolloid-like protein 1 TLL1 Tbio Non-IDG -1.40066 23.4 60
Zinc-alpha-2-glycoprotein AZGP1 Tbio Non-IDG -2.14317 164.1 198
MAP7 domain-containing protein 3 MAP7D3 Tbio Non-IDG -0.92082 8.05 8
Cysteine protease ATG4A ATG4A Tbio Enzyme -0.98696 7.89 199
Metallothionein 1H-like protein 1 MT1HL1 Tdark Non-IDG -1.46194 29.2 0
Sulfate transporter SLC26A2 Tbio Transporter -2.43817 275.5 68
Very-long-chain enoyl-CoA reductase TECR Tbio Enzyme -2.58601 380.5 85
Transmembrane protein 71 TMEM71 Tdark Non-IDG 0.70 0.12 8