Development Level

Tbio 73 | 11,445
Tchem 10 | 1,598
Tclin 5 | 613
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 8 | 979
cardiovascular system phenotyp... 2 | 36
embryonic lethality prior to o... 2 | 239
increased lean body mass 2 | 172
preweaning lethality, incomple... 2 | 499
abnormal allantois morphology 1 | 8
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal pancreas morphology 1 | 13
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin pigmentation 1 | 1
abnormal spleen morphology 1 | 55
cataract 1 | 92
cyanosis 1 | 7
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased bone mineral density 1 | 126
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
female infertility 1 | 60
increased anti-nuclear antigen... 1 | 19
increased anxiety-related resp... 1 | 2
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality 1 | 28
prolonged ST segment 1 | 36
short tibia 1 | 97
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 66 | 11,493
ovarian cancer 56 | 8,520
osteosarcoma 45 | 7,950
psoriasis 43 | 6,694
Cancer 37 | 2,499
lung cancer 37 | 4,740
Breast cancer 34 | 3,578
medulloblastoma, large-cell 32 | 6,241
glioblastoma 29 | 5,792
group 3 medulloblastoma 27 | 4,104
atypical teratoid / rhabdoid tumor 26 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
ependymoma 21 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
pancreatic cancer 21 | 2,398
Waldenstrons macroglobulinemia 20 | 765
invasive ductal carcinoma 20 | 2,951
Multiple myeloma 19 | 1,332
Kidney cancer 18 | 2,613
lung adenocarcinoma 18 | 2,716
malignant mesothelioma 18 | 3,232
non-small cell lung cancer 18 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
dermatomyositis 17 | 966
subependymal giant cell astrocytoma 17 | 2,287
colon cancer 16 | 1,478
Astrocytoma, Pilocytic 14 | 3,081
adrenocortical carcinoma 13 | 1,428
adult high grade glioma 13 | 3,801
primitive neuroectodermal tumor 13 | 3,035
ulcerative colitis 13 | 1,819
acute quadriplegic myopathy 12 | 1,158
Prostatic Neoplasms 11 | 495
ductal carcinoma in situ 11 | 1,745
lung carcinoma 11 | 2,843
astrocytoma 10 | 1,146
diabetes mellitus 10 | 1,728
group 4 medulloblastoma 10 | 1,855
nasopharyngeal carcinoma 10 | 1,058
pancreatic carcinoma 10 | 562
tuberculosis 10 | 2,010
Pick disease 9 | 1,894
breast carcinoma 9 | 1,638
oligodendroglioma 9 | 2,850
Breast Neoplasms 8 | 445
Liver Cirrhosis, Experimental 8 | 769
Schizophrenia 8 | 1,160
cystic fibrosis 8 | 1,696
interstitial cystitis 8 | 2,312
juvenile dermatomyositis 8 | 1,187
primary Sjogren syndrome 8 | 735
primary pancreatic ductal adenocarcinoma 8 | 1,109
Alzheimer's disease 7 | 658
Intellectual disability 7 | 1,016
Mammary Neoplasms 7 | 425
Rheumatoid arthritis 7 | 1,191
gastric cancer 7 | 459
progressive supranuclear palsy 7 | 676
spina bifida 7 | 1,074
Autosomal recessive predisposition 6 | 1,442
Neurodegenerative disease 6 | 414
Neuropathy 6 | 261
astrocytic glioma 6 | 2,597
cutaneous lupus erythematosus 6 | 1,057
medulloblastoma 6 | 720
Adenocarcinoma of lung 5 | 142
Amyotrophic lateral sclerosis 5 | 451
Asthma 5 | 385
Atopic dermatitis 5 | 952
Carcinoma, Hepatocellular 5 | 228
Disease Models, Animal 5 | 155
Duchenne muscular dystrophy 5 | 601
Kidney disease 5 | 430
Leukemia, Myelocytic, Acute 5 | 120
Liver carcinoma 5 | 240
Melanoma 5 | 711
Myocardial Ischemia 5 | 169
Neoplasm Metastasis 5 | 168
Prostate cancer 5 | 175
Stomach Neoplasms 5 | 300
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
esophageal adenocarcinoma 5 | 737
hepatocellular carcinoma 5 | 547
mucosa-associated lymphoid tissue lymphoma 5 | 484
non primary Sjogren syndrome sicca 5 | 891
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
Anemia 4 | 365
Bipolar Disorder 4 | 666
Depressive disorder 4 | 409
Down syndrome 4 | 499
Endometriosis 4 | 540
Heart disease 4 | 306
Mood Disorders 4 | 184
Multiple Sclerosis 4 | 540
Parkinson's disease 4 | 392
acute myeloid leukemia 4 | 783
gastric carcinoma 4 | 807
posterior fossa group B ependymoma 4 | 416

Tissue

Blood and immune system 89 | 16,909
Digestive Tract 88 | 17,369
Endocrine System 88 | 18,159
Female tissues 88 | 17,400
Male tissues 88 | 17,142
Nervous System 88 | 16,725
Skin and soft tissues 88 | 17,230
Liver and Pancreas 86 | 16,750
Urinary Tract 86 | 16,678
Respiratory system 84 | 16,393
Cardiovascular System 82 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 22 | 4,145
Transcription Factor 5 | 1,400
Epigenetic 4 | 242
Kinase 4 | 634
Ion Channel 3 | 344
GPCR 1 | 408

Jensen-KB Tissue

Prostate cancer cell line 91 | 91
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Pronephros 717 | 717
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA-binding protein Raly RALY Tbio Non-IDG -1.12263 14.4 176
Leucine-rich repeat-containing protein 26 LRRC26 Tbio Ion Channel -1.02699 11.3 81
Anterior gradient protein 2 homolog AGR2 Tbio Non-IDG -2.07496 136.6 594
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.30083 17.8 141
Jupiter microtubule associated homolog 1 JPT1 Tbio Non-IDG -2.53516 338.4 183
CTP synthase 1 CTPS1 Tbio Enzyme -2.29349 196.5 107
Sec1 family domain-containing protein 1 SCFD1 Tbio Non-IDG -1.50460 33.8 170
Tomoregulin-2 TMEFF2 Tbio Non-IDG -1.87758 86.0 194
DNA (cytosine-5)-methyltransferase 1 DNMT1 Tclin Enzyme -3.21333 1562.7 1125
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169