Development Level

Tbio 550 | 11,445
Tdark 93 | 6,588
Tchem 62 | 1,598
Tclin 12 | 613

Collection

RFA-RM-18-021 4 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 79 | 979
embryonic lethality prior to t... 20 | 278
embryonic lethality prior to o... 19 | 239
preweaning lethality, incomple... 19 | 499
abnormal embryo size 17 | 220
increased lean body mass 15 | 172
abnormal behavior 12 | 298
decreased total body fat amoun... 12 | 207
decreased body weight 10 | 161
abnormal heart morphology 9 | 162
hypoactivity 9 | 132
prenatal lethality prior to he... 9 | 87
decreased hematocrit 8 | 46
decreased prepulse inhibition 8 | 82
enlarged heart 8 | 210
increased total body fat amoun... 8 | 134
abnormal neural tube closure 7 | 46
decreased erythrocyte cell num... 7 | 62
decreased mean corpuscular hem... 7 | 50
abnormal behavioral response t... 6 | 66
abnormal bone structure 6 | 187
abnormal coat-hair pigmentatio... 6 | 64
decreased circulating choleste... 6 | 93
decreased circulating serum al... 6 | 82
decreased circulating triglyce... 6 | 79
decreased hemoglobin content 6 | 68
decreased startle reflex 6 | 75
embryonic growth retardation 6 | 106
increased bone mineral content 6 | 108
increased circulating alkaline... 6 | 122
increased or absent threshold ... 6 | 101
increased startle reflex 6 | 112
decreased bone mineral content 5 | 151
decreased lean body mass 5 | 135
hydrometra 5 | 53
improved glucose tolerance 5 | 79
limb grasping 5 | 41
small superior vagus ganglion 5 | 74
thrombocytosis 5 | 27
abnormal eye morphology 4 | 68
abnormal lens morphology 4 | 81
abnormal placenta size 4 | 20
abnormal skin coloration 4 | 25
cardiovascular system phenotyp... 4 | 36
corneal opacity 4 | 32
decreased body length 4 | 101
decreased caudal vertebrae num... 4 | 53
decreased circulating alanine ... 4 | 47
decreased circulating total pr... 4 | 49
decreased grip strength 4 | 116
decreased leukocyte cell numbe... 4 | 73
decreased lymphocyte cell numb... 4 | 83
decreased vertical activity 4 | 208
edema 4 | 59
hyperactivity 4 | 148
increased bone mineral density 4 | 72
increased circulating HDL chol... 4 | 80
increased circulating choleste... 4 | 66
male infertility 4 | 123
prolonged QT interval 4 | 38
prolonged ST segment 4 | 36
small testis 4 | 58
abnormal forebrain development 3 | 20
abnormal locomotor activation 3 | 16
abnormal pericardium morpholog... 3 | 26
abnormal seminal vesicle morph... 3 | 114
cataract 3 | 92
decreased blood urea nitrogen ... 3 | 51
decreased circulating fructosa... 3 | 30
decreased circulating insulin ... 3 | 76
decreased circulating iron lev... 3 | 32
decreased fasted circulating g... 3 | 65
decreased mean corpuscular vol... 3 | 79
enlarged uterus 3 | 11
hemorrhage 3 | 23
impaired glucose tolerance 3 | 75
impaired pupillary reflex 3 | 26
increased body temperature 3 | 9
increased circulating amylase ... 3 | 25
increased fasted circulating g... 3 | 76
increased mean corpuscular hem... 3 | 96
increased mean corpuscular vol... 3 | 92
increased mean platelet volume 3 | 45
increased monocyte cell number 3 | 63
increased red blood cell distr... 3 | 34
pale yolk sac 3 | 25
pallor 3 | 34
prenatal lethality 3 | 28
abnormal gait 2 | 69
abnormal liver size 2 | 5
abnormal retinal vasculature m... 2 | 27
anophthalmia 2 | 33
decreased circulating HDL chol... 2 | 68
decreased circulating creatini... 2 | 39
increased body weight 2 | 25
increased circulating fructosa... 2 | 13
increased circulating phosphat... 2 | 26
increased circulating sodium l... 2 | 71
microphthalmia 2 | 26
short tibia 2 | 97

Disease

Carcinoma 530 | 11,493
ovarian cancer 478 | 8,520
osteosarcoma 386 | 7,950
medulloblastoma, large-cell 291 | 6,241
glioblastoma 268 | 5,792
psoriasis 264 | 6,694
lung cancer 261 | 4,740
atypical teratoid / rhabdoid tumor 254 | 5,112
group 3 medulloblastoma 224 | 4,104
ependymoma 214 | 4,679
Kidney cancer 211 | 2,613
Breast cancer 194 | 3,578
malignant mesothelioma 160 | 3,232
Cancer 157 | 2,499
primitive neuroectodermal tumor 154 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 152 | 3,291
adult high grade glioma 146 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 139 | 2,989
oligodendroglioma 126 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 125 | 2,955
invasive ductal carcinoma 125 | 2,951
non-small cell lung cancer 122 | 2,890
lung adenocarcinoma 119 | 2,716
astrocytic glioma 113 | 2,597
Multiple myeloma 108 | 1,332
pancreatic cancer 106 | 2,398
Pick disease 105 | 1,894
group 4 medulloblastoma 91 | 1,855
Astrocytoma, Pilocytic 87 | 3,081
pancreatic ductal adenocarcinoma liver metastasis 86 | 1,962
subependymal giant cell astrocytoma 83 | 2,287
acute quadriplegic myopathy 82 | 1,158
Waldenstrons macroglobulinemia 81 | 765
colon cancer 80 | 1,478
dermatomyositis 80 | 966
Intellectual disability 79 | 1,016
pituitary cancer 74 | 1,972
juvenile dermatomyositis 72 | 1,187
astrocytoma 71 | 1,146
tuberculosis 68 | 2,010
diabetes mellitus 67 | 1,728
ductal carcinoma in situ 66 | 1,745
lung carcinoma 66 | 2,843
adrenocortical carcinoma 65 | 1,428
Rheumatoid arthritis 64 | 1,191
breast carcinoma 64 | 1,638
ulcerative colitis 63 | 1,819
interstitial cystitis 61 | 2,312
cystic fibrosis 59 | 1,696
pediatric high grade glioma 57 | 1,064
Autosomal recessive predisposition 54 | 1,442
Dull intelligence 51 | 645
Low intelligence 51 | 645
Mental Retardation 51 | 645
Mental deficiency 51 | 645
Poor school performance 51 | 645
acute myeloid leukemia 49 | 783
non primary Sjogren syndrome sicca 48 | 891
spina bifida 48 | 1,074
Liver cancer 47 | 604
primary pancreatic ductal adenocarcinoma 45 | 1,109
Cognitive delay 44 | 608
Global developmental delay 44 | 608
Mental and motor retardation 44 | 608
Short stature 44 | 531
nasopharyngeal carcinoma 44 | 1,058
Schizophrenia 43 | 1,160
Small head 40 | 374
medulloblastoma 39 | 720
Endometrial cancer 37 | 311
Epilepsy 36 | 792
Breast Neoplasms 34 | 445
progressive supranuclear palsy 34 | 676
Mammary Neoplasms 32 | 425
Muscle hypotonia 32 | 571
gastric carcinoma 32 | 807
Amyotrophic lateral sclerosis 31 | 451
Endometriosis 30 | 540
Strabismus 30 | 270
tuberculosis and treatment for 6 months 30 | 409
Alzheimer's disease 29 | 658
Melanoma 29 | 711
Seizures 29 | 596
primary Sjogren syndrome 29 | 735
aldosterone-producing adenoma 27 | 665
Cryptorchidism 26 | 296
hepatocellular carcinoma 26 | 547
Duchenne muscular dystrophy 25 | 601
Fetal Growth Retardation 25 | 189
Hypoplastic mandible condyle 25 | 275
Infant, Small for Gestational Age 25 | 176
Intrauterine retardation 25 | 176
Mandibular hypoplasia 25 | 275
Micrognathism 25 | 275
active Crohn's disease 25 | 922
pancreatic carcinoma 25 | 562
Atopic dermatitis 24 | 952
autosomal dominant Emery-Dreifuss muscular dystrophy 24 | 510
Bipolar Disorder 23 | 666
Prostatic Neoplasms 23 | 495

Tissue

Endocrine System 706 | 18,159
Digestive Tract 705 | 17,369
Female tissues 704 | 17,400
Male tissues 704 | 17,142
Liver and Pancreas 703 | 16,750
Skin and soft tissues 703 | 17,230
Urinary Tract 703 | 16,678
Blood and immune system 702 | 16,909
Respiratory system 701 | 16,393
Nervous System 700 | 16,725
Cardiovascular System 689 | 15,192

Target Family

Non-IDG 406 | 12,091
Enzyme 178 | 4,145
Transcription Factor 58 | 1,400
Epigenetic 30 | 242
Kinase 22 | 634
Transporter 11 | 473
GPCR 4 | 408
TF/Epigenetic 4 | 38
Ion Channel 3 | 344
Nuclear Receptor 1 | 48

Jensen-KB Tissue

Pronephros 717 | 717
Brain 7,346 | 7,346
Liver 5,008 | 5,008
Cervical carcinoma cell 4,944 | 4,944
Erythroleukemia cell 4,300 | 4,300
Testis 3,897 | 3,897
Placenta 3,079 | 3,079
T-cell chronic lymphocytic leu... 2,346 | 2,346
Lung 2,286 | 2,286
Skin 1,556 | 1,556
Uterus 1,493 | 1,493
Kidney 1,299 | 1,299
Colon 1,063 | 1,063
Eye 856 | 856
Pancreas 833 | 833
Muscle 725 | 725
Cerebellum 698 | 698
Ovary 691 | 691
Bone marrow 636 | 636
Amygdala 627 | 627
Spleen 620 | 620
Teratocarcinoma cell 604 | 604
Heart 583 | 583
Blood 567 | 567
Lymph 563 | 563
Colonic cancer cell 562 | 562
Skeletal muscle 549 | 549
Blood platelet 538 | 538
Hippocampus 531 | 531
Trachea 525 | 525
Tongue 470 | 470
Prostate gland epithelium 457 | 457
Thymus 427 | 427
Uterine cervix 418 | 418
Mammary gland 415 | 415
Melanoma cell line 364 | 364
BTO:0000379 352 | 352
Umbilical cord blood 344 | 344
Retina 337 | 337
Thalamus 331 | 331
Small intestine 330 | 330
T-lymphocyte 286 | 286
Plasma cell 284 | 284
B-lymphocyte cell line 272 | 272
Hepatoma cell 244 | 244
Urinary bladder 228 | 228
Breast cancer cell 221 | 221
Brain cortex cell line 215 | 215
Leukocyte 206 | 206
CL-48 cell 200 | 200
Interstitial cell of Cajal 192 | 192
Neuroblastoma cell 187 | 187
Ovary cancer cell 185 | 185
Peripheral nervous system 184 | 184
Stomach 182 | 182
Adrenal gland 177 | 177
Cerebral cortex 159 | 159
Lymph node 151 | 151
Synovium 148 | 148
Thyroid gland 144 | 144
Fibroblast 139 | 139
Keratinocyte 139 | 139
Adipose tissue 136 | 136
Duodenum 136 | 136
Peripheral blood 134 | 134
B-cell lymphoma cell 130 | 130
Hypophysis 128 | 128
Uterine endometrium 122 | 122
Hypothalamus 117 | 117
Subthalamic nucleus 114 | 114
Caudate nucleus 109 | 109
Lung cancer cell 103 | 103
Prostate cancer cell line 91 | 91
Aorta 86 | 86
Lymphocyte 86 | 86
Retinoblastoma cell 84 | 84
Colonic adenocarcinoma cell 81 | 81
Monocyte 78 | 78
Dendritic cell 77 | 77
Lymphoblast 74 | 74
Salivary gland 74 | 74
Spinal cord 74 | 74
Substantia nigra 73 | 73
Renal cell carcinoma cell 72 | 72
Leukemia cell 69 | 69
Corpus callosum 67 | 67
Esophagus 65 | 65
Lymphoid tissue 60 | 60
Scalp 59 | 59
Endothelial cell 57 | 57
Saliva 56 | 56
Colonic mucosa 55 | 55
Hair root 55 | 55
Lymphoma cell 53 | 53
Gastric mucosa 52 | 52
Bone 51 | 51
Pericardium 50 | 50
Prepuce 50 | 50
Umbilical vein endothelial cel... 49 | 49
Uterine endometrial cancer cel... 49 | 49

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Septin-11 SEPT11 Tbio Non-IDG -1.47747 32.4 127
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Zinc finger protein 638 ZNF638 Tbio Non-IDG -0.68946 6.04 67
Leucine-rich repeat flightless-interacting protein 2 LRRFIP2 Tbio Non-IDG -0.65733 4.88 129
KN motif and ankyrin repeat domain-containing protein 2 KANK2 Tbio Non-IDG -0.97803 8.39 131
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Chromodomain-helicase-DNA-binding protein 4 CHD4 Tbio Epigenetic -2.22229 159.7 203
Plakophilin-2 PKP2 Tbio Non-IDG -2.10355 135.3 243
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Polyadenylate-binding protein 4-like PABPC4L Tdark Non-IDG 0.00000 1.00 49